CN112155212A - Rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying and preparation method thereof - Google Patents
Rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying and preparation method thereof Download PDFInfo
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- CN112155212A CN112155212A CN202010953661.1A CN202010953661A CN112155212A CN 112155212 A CN112155212 A CN 112155212A CN 202010953661 A CN202010953661 A CN 202010953661A CN 112155212 A CN112155212 A CN 112155212A
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- beautifying
- oligosaccharide
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- detoxifying
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- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 title claims abstract description 42
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- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 title claims abstract description 42
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- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- WWUZIQQURGPMPG-KRWOKUGFSA-N sphingosine Chemical compound CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO WWUZIQQURGPMPG-KRWOKUGFSA-N 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the technical field of health-care food. The invention discloses a rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying, which is prepared from fructo-oligosaccharide, galacto-oligosaccharide, xylo-oligosaccharide, inulin, lotus leaf, fructus cannabis, rice ceramide, pomegranate juice, citric acid, sodium citrate and edible essence; the invention also discloses a preparation method of the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying, which comprises the steps of extracting lotus leaf and fructus cannabis, dissolving small materials, adding materials and post-treating with a sodium citrate additive. The rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying has good taste and convenient drinking, and caters to the consumption trend of modern people; according to the invention, fructo-oligosaccharide, galacto-oligosaccharide and inulin proliferate specific lactobacillus and bifidobacterium; xylo-oligosaccharides proliferate specific bifidobacteria; adds value to all prebiotics in the intestinal tract, synergistically grows, inhibits the growth of harmful bacteria, and regulates the balance of intestinal flora.
Description
Technical Field
The invention relates to the technical field of health-care food, in particular to a rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying and a preparation method thereof.
Background
With the development of economy and the improvement of living standard, people are more and more urgent to pursue beauty, and the beauty and the young are continuously maintained through cosmetics and skin care products. However, in recent years, more and more women have recognized that cosmetic skin care products alone cannot solve all the problems of beauty, and only by conditioning from the inside, beauty from the inside to the outside can be fundamentally realized. Therefore, the oral beauty drink is more and more concerned and pursued by women loving beauty. In the oral beauty market, collagen is unique, and collagen products are full of line on the market, however, most of the collagen products in the market only have the effects of whitening and tendering skin, and the oral moisturizing products are basically ignored.
With age, the normal stratum corneum water content is reduced. If the skin is dried without paying attention to the moisture retention, the increase of wrinkles is inevitably caused. After long-term development, wrinkles are inevitably distributed on the skin. When the water content in our skin stratum corneum is less than 10%, it is an indication that our skin has begun to run out of water. Skin is more likely to be skinned as it is drier. When the skin dries to a normal state, it is difficult to relieve it again by daily care. Skin that is skinned for a long time not only looks like a lack of spirit, but also affects mental health. Chronic dry skin is also a cause of several diseases such as psoriasis, ichthyosis, etc.
It is well known that women are more likely to constipation than men, and that constipation leads to the production of daily unused waste in the human gut, which accumulates to form "stubborn stool". The stubborn stool accumulated in the intestines can cause symptoms of abdominal distension, halitosis, dizziness, inappetence, hypodynamia and the like, and the stubborn stool accumulated in the intestines is continuously fermented and decayed due to the action of bacteria to generate harmful toxin gas which is absorbed into blood to stimulate and poison the skin, thereby causing skin diseases such as facial freckles, acnes, pustules, pimples, rough skin and the like. Therefore, to achieve the beauty from inside to outside fundamentally, moistening the intestines and freeing the bowels is the first step.
Disclosure of Invention
In order to solve the problems, the invention provides the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying, which can relax bowel and relieve constipation and also can moisturize and beautify the skin;
the invention also provides a preparation method of the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying, the method is simple and easy to implement, the raw materials are specially processed, the nutritional ingredients in the raw materials are fully extracted, the taste and the nutrition are richer, the product success rate is high, and the industrial mass production is facilitated.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
a rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying comprises the following raw materials in percentage by weight:
100-300 parts of fructo-oligosaccharide, 100-300 parts of galacto-oligosaccharide, 10-100 parts of xylo-oligosaccharide, 10-100 parts of inulin, 10-100 parts of lotus leaf, 10-100 parts of fructus cannabis, 0.1-6 parts of rice ceramide, 10-60 parts of pomegranate juice, 1-50 parts of citric acid, 0.5-50 parts of sodium citrate and 0.5-5 parts of edible essence; meanwhile, the water-based coating material comprises a proper amount of water, and the weight parts of the raw materials and the water are 950-1050 parts.
Preferably, the weight sum of the fructo-oligosaccharide and the inulin is 11-30% of the weight of the raw materials except water.
Rice ceramide is a ceramide extracted and refined from rice, is N-acyl sphingosine, is a compound formed by combining sphingosine and fatty acid through amide bonds, and has the functions of whitening, moisturizing, resisting aging, protecting skin and the like. Ceramide is the main component of intercellular lipid of stratum corneum, and is about 40-60% of the total amount; its excellent hydrophilic performance and unique arrangement mode can effectively prevent water loss. The content of ceramide in the horny layer is reduced along with the aging, meanwhile, the content of ceramide in the horny layer can be reduced due to atopic dermatitis and the like, and the ceramide in the skin can be increased after the rice ceramide is orally taken, so that the water holding capacity of the skin is improved.
Pomegranate contains rich antioxidant bioactive substances such as tannin, anthocyanin, flavonoid, etc., wherein the most important are ellagic acid tannin punicalagin and ellagic acid. Ellagic acid is a well-known significant whitening ingredient and was published and approved by the world health organization as a new whitening ingredient in 2004. Has obvious anti-saccharification effect: inhibiting the generation of AGEs, promoting the decomposition of AGEs, resisting oxidation, and inhibiting melanin deposition.
The fructo-oligosaccharide can promote the growth of beneficial bacteria such as lactobacillus and bifidobacterium in the intestinal tract, and the beneficial bacteria can generate short-chain fatty acids, wherein the short-chain fatty acids are mainly acetic acid, propionic acid and butyric acid, and can maintain the acidic environment of the intestinal tract, thereby inhibiting the growth and reproduction of pathogenic bacteria and maintaining the microecological balance of the intestinal tract.
Galacto-oligosaccharide is one of the functional oligosaccharides that have been developed internationally at present, and it is a functional oligosaccharide with natural properties. In nature, animal milk contains trace amount of galactooligosaccharide, human breast milk contains more galactooligosaccharide, and the establishment of bifidobacterium flora in infants depends on the galactooligosaccharide component in the breast milk to a great extent. It is an important prebiotic in breast milk and its safety has been widely recognized. The galactooligosaccharide has the effects of proliferating intestinal Bacillus bifidus and lactobacillus simultaneously, inhibiting growth of harmful bacteria, promoting gastrointestinal peristalsis, and improving intestinal function. Galactooligosaccharides are the only ones that can be utilized by the 8 large beneficial bacteria in the human intestine.
Xylo-oligosaccharide is the oligosaccharide which is found to be effective in the minimum dosage at present, and the effective intake is 0.7-1.5 g/d. The xylo-oligosaccharide has high selective proliferation effect on probiotics such as bifidobacterium, lactobacillus and the like, but has obvious inhibition effect on pathogenic bacteria such as escherichia coli, enterococcus, clostridium and the like. The capacity of proliferating bifidobacteria is 20 times higher than other oligosaccharides.
Lotus leaves, recorded in compendium of materia Medica, "lotus leaves are fit to be thin and bad". Modern pharmacological research shows that the lotus leaf has multiple biological activities of resisting oxidation, reducing fat, losing weight, treating cardiovascular diseases and the like. The main active ingredients of the lotus leaves are flavonoids and alkaloids substances, and the lotus leaves can effectively decompose fat in vivo and can be discharged out of the body strongly. Nuciferine can be strongly and densely distributed on the intestinal wall of a human body to form a fat isolation film to prevent fat absorption and fat accumulation, and has a strong fat rejection effect, so that people can gradually feel dislike meat, fishy and greasy food. Therefore, has excellent weight-losing efficacy and excellent lipid-lowering effect.
Huo Ma ren, recorded in Shen nong Ben Cao Jing (Shen nong's herbal), is listed as the top grade, has the effects of nourishing yin, tonifying deficiency, moistening dryness, lubricating intestines, tonifying middle-jiao and Qi, etc. Fructus Cannabis has bidirectional therapeutic effect on constipation and diarrhea. Fructus cannabis can stimulate intestinal mucosa, increase secretion, accelerate peristalsis, reduce water absorption of large intestine and has purgative effect, and traditional Chinese medicine is commonly used as a formula component for treating constipation clinically and can also be used for treating constipation symptoms caused by psychotropic drugs.
The oral liquid has the advantages that the raw materials are simple and easy to obtain and moderate in cost, the formula is used for carrying out a large number of experiments on the screening of the types of the raw materials, the used raw materials are compared with the products and the processes of various suppliers, the taste is selected through comparative evaluation, the proportion is also the optimal dosage scientifically optimized through a large number of scientific experimental designs and practices, and the health of the preparation can be guaranteed only on the premise of adding the raw materials and the proportion of the raw materials; especially, the addition amount of fructo-oligosaccharide and inulin is required to be between 11% and 30%, no body feeling exists below 11%, and body feeling is too strong above 30%, so that the experience of consumers is seriously influenced.
A preparation method of an oral liquid containing rice ceramide for moisturizing, beautifying, detoxifying and beautifying comprises the following steps:
a) extracting lotus leaves and fructus cannabis: crushing lotus leaves and fructus cannabis, then leaching with hot water, filtering after leaching, and concentrating the filtrate to obtain the concentrated juice with the density of 1.02-1.08 g/cm3Obtaining concentrated solution of lotus leaves and fructus cannabis for later use;
b) dissolving small materials: dissolving xylo-oligosaccharide and inulin in hot water to obtain a feed liquid, and inputting the feed liquid into a mixing tank;
c) material input: adding fructo-oligosaccharide, galacto-oligosaccharide, pomegranate juice, edible essence and concentrated lotus leaf and fructus cannabis solution into a mixing tank;
d) adding citric acid and sodium citrate: dissolving citric acid and sodium citrate in hot water to obtain an acid solution, and adding the acid solution into a dosing tank; e) and (5) post-treatment.
Preferably, the step a) is specifically that the lotus leaves and the fructus cannabis are crushed and sieved by a sieve of 15-25 meshes, the lotus leaves and the fructus cannabis are placed in an extraction tank, 8-12 times of hot water with the temperature of 85-95 ℃ is added, heat preservation stirring extraction is carried out for 1.5-2.5 hours, filtering is carried out, 6-10 times of hot water with the temperature of 85-95 ℃ is added into filter residues, heat preservation stirring extraction is carried out for 0.5-1.5 hours, filtering is carried out, filtrates obtained in two times of extraction are combined, and vacuum concentration is carried out until the density is 1.02-1.3Obtaining concentrated solution of lotus leaves and fructus cannabis for later use.
Preferably, the step b) is specifically that 180-220L of 85-95 ℃ hot water is added into a small material tank, stirring is carried out, the small material tank is started to circulate, xylo-oligosaccharide is added firstly, inulin is added after stirring is carried out for 4-6 minutes, the inulin is added and stirred to be completely dissolved, and then the prepared feed liquid is input into a material mixing tank.
Preferably, the step d) is specifically to add citric acid and sodium citrate into 8-12L of 85-95 ℃ hot water, stir to completely dissolve the citric acid and the sodium citrate to obtain an acid solution, and add the acid solution into the batching tank.
Preferably, the acid solution is added to the batching tank after all other raw materials are added to the batching tank. I.e., the acid solution is added last to the batching tank.
Preferably, the step e) is specifically that the rest of water is added, and the mixture is stirred to uniformly mix the feed liquid; and (5) filling and sterilizing.
Therefore, the invention has the following beneficial effects:
1. the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying has good taste and convenient drinking, and caters to the consumption trend of modern people;
2. the rice ceramide used in the invention is safe and effective to take orally, and is matched with pomegranate juice with various beauty benefits such as oxidation resistance, saccharification resistance and the like, so that the moisture is preserved, the color spots and the whiteness of skin are improved, and the moisture preservation and the beauty are realized;
3. according to the invention, fructo-oligosaccharide, galacto-oligosaccharide, xylo-oligosaccharide and inulin are combined, and the fructo-oligosaccharide, galacto-oligosaccharide and inulin proliferate specific lactobacillus and bifidobacterium; xylo-oligosaccharides proliferate specific bifidobacteria; each has a strong emphasis on the value-added and synergistic growth of all prebiotics in the intestinal tract; inhibiting the growth of harmful bacteria and regulating the balance of intestinal flora; the lotus leaves and the fructus cannabis can promote intestinal peristalsis and coordinate with the effect of moistening.
Detailed Description
The technical solution of the present invention will be further described with reference to the following embodiments.
It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the present invention, all the equipments and materials are commercially available or commonly used in the industry, and the methods in the following examples are conventional in the art unless otherwise specified.
General examples
A rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying comprises the following raw materials in percentage by weight:
100-300 parts of fructo-oligosaccharide, 100-300 parts of galacto-oligosaccharide, 10-100 parts of xylo-oligosaccharide, 10-100 parts of inulin, 10-100 parts of lotus leaf, 10-100 parts of fructus cannabis, 0.1-6 parts of rice ceramide, 10-60 parts of pomegranate juice, 1-50 parts of citric acid, 0.5-50 parts of sodium citrate and 0.5-5 parts of edible essence; meanwhile, the fertilizer contains a proper amount of water, and the total weight of the raw materials and the water is 950-1050 parts; the weight sum of the fructo-oligosaccharide and the inulin is 11-30% of the weight of the raw materials except water.
A preparation method of an oral liquid containing rice ceramide for moisturizing, beautifying, detoxifying and beautifying comprises the following steps:
a) extracting lotus leaves and fructus cannabis: crushing lotus leaves and fructus cannabis, sieving the crushed lotus leaves and fructus cannabis with a 15-25-mesh sieve, putting the crushed lotus leaves and fructus cannabis into an extraction tank, adding 8-12 times of 85-95 ℃ hot water, performing heat preservation stirring extraction for 1.5-2.5 hours, filtering, adding 6-10 times of 85-95 ℃ hot water into filter residues, performing heat preservation stirring extraction for 0.5-1.5 hours, filtering, combining filtrates obtained by two times of extraction, and performing vacuum concentration until the density is 1.02-1.08 g/cm3Obtaining concentrated solution of lotus leaves and fructus cannabis for later use;
b) dissolving small materials: adding 180-220L of hot water with the temperature of 85-95 ℃ into a small material tank, stirring, starting the small material tank to circulate, adding xylo-oligosaccharide, stirring for 4-6 minutes, then adding inulin, stirring to completely dissolve the inulin, and inputting the prepared feed liquid into a material mixing tank;
c) material input: adding fructo-oligosaccharide, galacto-oligosaccharide, pomegranate juice, edible essence and concentrated lotus leaf and fructus cannabis solution into a mixing tank;
d) adding citric acid and sodium citrate: adding citric acid and sodium citrate into 8-12L of 85-95 ℃ hot water, stirring to completely dissolve to obtain an acid solution, adding the citric acid and sodium citrate solution into a mixing tank, and finally adding the acid solution in all the raw materials into the mixing tank;
e) and (3) post-treatment: adding the balance of water, and stirring to uniformly mix the feed liquid; and (5) filling and sterilizing.
Examples 1 to 3:
the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying, which is disclosed by the invention, is prepared according to the ingredients in the following table 1.
Table 1: EXAMPLES 1 to 3 ingredients
The preparation method of the embodiment 1-3 is as follows:
a) extracting lotus leaves and fructus cannabis: pulverizing folium Nelumbinis and fructus Cannabis, sieving with 20 mesh sieve, placing into extraction tank, adding 10 times of 90 deg.C hot water, extracting under stirring for 2 hr, filtering, adding 8 times of 90 deg.C hot water into the residue, extracting under stirring for 1 hr, filtering, mixing the filtrates, vacuum concentrating to density of 1.05g/cm3Obtaining concentrated solution of lotus leaves and fructus cannabis for later use;
b) dissolving small materials: adding 200L of 90 ℃ hot water into a small material tank, stirring, starting the small material tank to circulate, adding xylo-oligosaccharide, stirring for 5 minutes, adding inulin, stirring for 10 minutes to completely dissolve the inulin, and then starting an infusion pump to input the prepared material liquid into the material tank;
c) material input: adding fructo-oligosaccharide, galacto-oligosaccharide, pomegranate juice, edible essence and concentrated lotus leaf and fructus cannabis solution into a mixing tank;
d) adding citric acid and sodium citrate: adding citric acid and sodium citrate into 10L of 90 ℃ hot water, stirring to completely dissolve to obtain an acid solution, and adding the citric acid and sodium citrate solution into a mixing tank; adding acid solution in all the raw materials into a batching tank at last;
e) and (3) post-treatment: adding the balance of water, and stirring for 15 minutes to uniformly mix the feed liquid; the 50mL glass bottles were filled and sterilized.
Comparative examples 1 to 7:
the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying, which is disclosed by the invention, is prepared according to the ingredients in the following table 2.
Table 2 comparative examples 1 to 7 were compounded:
the preparation method of comparative examples 1 to 7 is the same as that of examples 1 to 3, and the corresponding preparation steps are omitted for components not included in comparative examples 1 to 7.
The following trial experiments of the oral liquid are described below.
Firstly, intestinal flora experiment:
1. comparative examples 1,2, 3, 4 and example 1 compared, 50 women of 25-60 years old were searched in this market for voluntary experiments, with the average age at 41.3 years. The experimenters had different constipation problems, and were divided into 5 groups on average according to age, with no statistical difference between groups. Each group of experimenters respectively eat the oral liquid of the embodiment and the comparative example, and take the oral liquid once a day before sleeping, 1 bottle each time, and respectively carry out intestinal flora determination before trial taking and after 30 days.
Before test taking and after 12h of last taking, taking feces aseptically, diluting in 10 times series, and selecting appropriate dilution to inoculate on BBL, sodium azide-crystal violet-esculin, eosin methylene blue, LBS, TSC and modified GAM agar medium. After culturing, identifying and counting bacterial colonies according to bacterial colony morphology, gram staining microscopy, biochemical reaction and the like, calculating the number of bacteria in wet excrement per gram, and taking the number of the bacteria to perform statistical treatment.
2. The experimental results are shown in table 3 below;
table 3:
before the test, the values of bifidobacterium + enterococcus + enterobacter + lactobacillus and clostridium perfringens + bacteroides of the groups of the comparative examples 1,2, 3 and 4 and the example 1 are not obviously different and have comparability. After the test clothes of comparative examples 1,2, 3 and 4 and example 1, the values of bifidobacterium, enterococcus, enterobacter and lactobacillus are increased, and various prebiotic combinations are shown to have the proliferation effect on probiotics such as bifidobacterium, enterobacter, lactobacillus and the like and the inhibition effect on harmful bacteria such as clostridium perfringens and bacteroides and the like, and compared with example 1, the formula of the comparative example 1 is less in fructooligosaccharide; comparative example 2 compared to example 1, the formulation had less galacto-oligosaccharides; comparative example 3 compared to example 1, there was less xylo-oligosaccharide in the formulation; comparative example 4 inulin was omitted from the formulation relative to example 1; comparative examples 1,2, 3, and 4 with respect to example 1, example 1 showed the greatest increase in beneficial bacteria and the greatest decrease in harmful bacteria, and it is sufficient to show that the combination of fructooligosaccharide + galactooligosaccharide + xylooligosaccharide + inulin is superior to any three of them.
Second, study of moisturizing and beautifying effects
1. Comparative examples 5, 6 and 7 and examples 1,2 and 3, 60 women of 25 to 45 years old were searched in this market for voluntary experiments, with the average age at 35.6 years. The experimenters have different skin problems, and are averagely divided into 6 groups according to skin and age states, and the groups have no statistical difference. The oral liquids of the examples and the comparative examples were taken once a day by 1 bottle each time before sleeping by each group of experimenters.
2. The experimental results are shown in table 4 below;
table 4:
as is clear from the experimental results, examples 1,2 and 3 showed little difference in the effects of lightening skin spots, improving the whiteness of skin and increasing the moisturization of skin.
Compared with the comparative example 5, the example 1 has one more phytoceramide rice ceramide, and the result shows that the difference is the largest skin moisture degree within 3 months, the comparative example 5 is not improved basically after 3 months, the example 1 is improved by 50 percent, the difference is huge, and simultaneously, the reduction of the mottle degree and the skin whiteness degree is also obvious in the example 1, thereby showing that the phytoceramide rice ceramide has an important effect on moisturizing and beautifying.
Comparative example 6 compared with example 1, the product does not contain fructo-oligosaccharide solution, galacto-oligosaccharide solution, xylo-oligosaccharide and inulin, and the result shows that the color spot development degree, the skin whiteness and the skin moisture degree are all inferior to those of example 1 in 1 month, 2 months and 3 months, which shows that the fructo-oligosaccharide solution, the galacto-oligosaccharide solution, the xylo-oligosaccharide and the inulin can relax the bowel to achieve the effects of expelling toxin and beautifying, and meanwhile, the lotus leaf and fructus cannabis are added to benefit the effects of expelling toxin and beautifying.
The results of comparative example 7 and example 1 lack lotus leaves and fructus cannabis, and show that the color spot development degree, the skin whiteness degree and the skin moisture degree are inferior to those of example 1 in 1 month, 2 months and 3 months, so that the lotus leaves and fructus cannabis have the promotion effect on relaxing bowel and expelling toxin and beautifying.
In conclusion, the phytoceramide rice ceramide can increase the skin moisture, and the pomegranate juice can lighten color spots and whiten the skin, so that the combination effect of the phytoceramide rice ceramide and the pomegranate juice is better; the fructo-oligosaccharide liquid, the galacto-oligosaccharide liquid, the xylo-oligosaccharide and the inulin can regulate intestinal tracts, promote the growth of beneficial bacteria and inhibit the growth of harmful bacteria so as to inhibit the generation of toxins, and the lotus leaves and the fructus cannabis have the effect of relaxing bowel.
Third, study of laxative action
1. Comparative examples 6 and 7 were compared with example 1, and 60 constipation patients collected from a hospital in this city were randomly selected, each half of the patients was aged 30-50 years, the average age was 40.5 years, the course of disease was 2-5 years, and the average was 3.1 years.
2. Patients were divided on average into 3 groups with no statistical difference between groups. Each group of patients consumed the oral liquid of example 1 and the oral liquid of the comparative example once a day, and drunk 1 bottle each time in an empty stomach every day. The administration is continued for 2 weeks.
3. Basis of evaluation
The evaluation of the experimental results was based on "notice of issue (health food inspection and evaluation technical specification) (2003 edition) by the ministry of health issued on 24.2.2003 by the ministry of health.
4. The influence of defecation times
TABLE 5 comparison of defecation times before and during use (times/week) (+ -SD)
| Grouping | Number of examples | Before use | Second week after use | Difference value |
| Example 1 | 20 | 2.37±0.59 | 5.8±0.85 | 3.43±0.63 |
| Comparative example 6 | 20 | 2.41±0.68 | 3.98±0.67 | 1.59±0.78 |
| Comparative example 7 | 20 | 2.39±0.65 | 4.95±0.55 | 2.54±0.62 |
Before the test, the defecation times of the groups of example 1 and comparative examples 6 and 7 are not obviously different and are comparable. The number of stools in the group of example 1 was significantly increased the second week after use of example 1, compared to before use.
Comparative example 6 increased the number of stools compared with before and after 2 weeks of use, but the increased number of stools was slightly smaller compared with after two weeks of example 1, indicating that fructo-oligosaccharide, galacto-oligosaccharide, xylo-oligosaccharide and inulin have an accelerating effect on the number of stools.
Comparative example 7 increased the number of stools compared with 2 weeks before use, but slightly less after two weeks compared with example 1, indicating that lotus leaves and hemp seeds have an accelerating effect on the number of stools.
5. Influence of defecation
TABLE 6 integral comparison of fecal status before and during use (+ -SD)
| Grouping | Number of examples | Before use | Second week after use | Difference value |
| Example 1 | 20 | 1.85±0.66 | 0.72±0.50 | 1.13±0.57 |
| Comparative example 6 | 20 | 1.86±0.72 | 1.21±0.83 | 0.65±0.75 |
| Comparative example 7 | 20 | 1.88±0.59 | 0.92±0.52 | 0.96±0.63 |
Before the test feeding, the integral of the fecal status of the groups of example 1 and comparative examples 2 and 3 has no significant difference and has comparability. The fecal status score for the group of example 1 was significantly lower than that before the group of example 1, the second week after the group of example 1 was used.
Comparative example 6 the integral of fecal status decreased before and after 2 weeks of use, but the integral of fecal status decreased slightly less compared to example 1 after two weeks, indicating that fructooligosaccharides, galactooligosaccharides, xylooligosaccharides and inulin have a promoting effect on the integral of fecal status.
Comparative example 7 the integral of fecal status decreased before use compared to 2 weeks of use, but the integral of fecal status decreased slightly less compared to two weeks of example 1, indicating that lotus leaf and hemp seed have a promoting effect on the integral of fecal status.
6. Effect of defecation Properties
TABLE 7 comparison of fecal character integral before and during use (+ -SD)
| Grouping | Number of examples | Before use | Second week after use | Difference value |
| Example 1 | 20 | 1.35±0.68 | 0.71±0.33 | 0.64±0.54 |
| Comparative example 6 | 20 | 1.32±0.58 | 0.99±0.49 | 0.33±0.63 |
| Comparative example 7 | 20 | 1.33±0.65 | 0.86±0.63 | 0.47±0.67 |
Before the test feeding, the fecal character scores of the example 1 and the comparative examples 2 and 3 are not obviously different and have comparability. The second week after example 1 use, the fecal trait score for the example 1 group was significantly lower than before use.
Comparative example 6 the integral of fecal properties decreased compared before and after 2 weeks of use, but the integral of fecal status decreased slightly less compared to example 1 after two weeks, indicating that fructooligosaccharides, galactooligosaccharides, xylooligosaccharides and inulin have a promoting effect on the integral of fecal properties.
Comparative example 7 the stool trait score decreased before and after 2 weeks of use, but the stool trait score decreased slightly less after two weeks of use compared to example 1, indicating that lotus leaf and hemp seed have a promoting effect on the stool trait score.
From the above results, it is found that fructo-oligosaccharide, galacto-oligosaccharide, xylo-oligosaccharide, inulin, lotus leaf and fructus cannabis are all used to promote the increase of defecation frequency, the decrease of the integral of fecal status and the integral of fecal traits, but none of them is necessary.
7. Conclusion
The results show that: after the oral liquid is used, the color spot, the skin whiteness and the skin moisture are greatly improved, and the defecation frequency, the defecation condition and the defecation shape are also greatly improved. In conclusion, the combination mode of the invention can generate mutual synergistic effect, thereby effectively improving the skin condition and maintaining beauty and keeping young.
The rice ceramide can increase skin moisture, the pomegranate juice can lighten color spots and skin whiteness, and the combination of the rice ceramide and the pomegranate juice has prominent moisturizing and beautifying effects; the fructo-oligosaccharide liquid, the galacto-oligosaccharide liquid, the xylo-oligosaccharide and the inulin have synergistic effect and can regulate intestinal tracts, promote the growth of beneficial bacteria and inhibit the growth of harmful bacteria so as to inhibit the generation of toxins, and the lotus leaves and the fructus cannabis have the effect of relaxing bowels. Meanwhile, on the basis of promoting toxin expelling and beautifying, the moisturizing and beautifying effects of the rice ceramide and the pomegranate juice can be promoted, and the beauty from inside to outside is realized.
It will be understood that modifications and variations can be made by persons skilled in the art in light of the above teachings and all such modifications and variations are intended to be included within the scope of the invention as defined in the appended claims.
Claims (8)
1. The rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying is characterized by comprising the following raw materials in parts by weight:
100-300 parts of fructo-oligosaccharide, 100-300 parts of galacto-oligosaccharide, 10-100 parts of xylo-oligosaccharide, 10-100 parts of inulin, 10-100 parts of lotus leaf, 10-100 parts of fructus cannabis, 0.1-6 parts of rice ceramide, 10-60 parts of pomegranate juice, 1-50 parts of citric acid, 0.5-50 parts of sodium citrate and 0.5-5 parts of edible essence; meanwhile, the water treatment agent comprises a proper amount of water, and the total weight of the raw materials and the water is 950-1050 parts.
2. The rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying as claimed in claim 1, is characterized in that:
the sum of the weight of the fructo-oligosaccharide and the weight of the inulin is 11-30% of the weight of the raw materials except water.
3. A preparation method of an oral liquid containing rice ceramide for moisturizing, beautifying, detoxifying and beautifying is characterized by comprising the following steps:
a) extracting lotus leaves and fructus cannabis: crushing lotus leaves and fructus cannabis, then leaching with hot water, filtering after leaching, and concentrating the filtrate to obtain the concentrated juice with the density of 1.02-1.05 g/cm3Obtaining concentrated solution of lotus leaves and fructus cannabis for later use;
b) dissolving small materials: dissolving xylo-oligosaccharide and inulin in hot water to obtain a feed liquid, and inputting the feed liquid into a mixing tank;
c) material input: adding fructo-oligosaccharide, galacto-oligosaccharide, pomegranate juice, edible essence and concentrated lotus leaf and fructus cannabis solution into a mixing tank;
d) adding citric acid and sodium citrate: dissolving citric acid and sodium citrate in hot water to obtain an acid solution, and adding the acid solution into a dosing tank;
e) and (5) post-treatment.
4. The preparation method of the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying according to claim 3 is characterized by comprising the following steps of:
the step a) is specifically that lotus leaves and fructus cannabis are crushed and sieved by a sieve of 15-25 meshes, the lotus leaves and fructus cannabis are placed in an extraction tank, 8-12 times of hot water at 85-95 ℃ is added, heat preservation stirring extraction is carried out for 1.5-2.5 hours, filtering is carried out, 6-10 times of hot water at 85-95 ℃ is added into filter residues, heat preservation stirring extraction is carried out for 0.5-1.5 hours, filtering is carried out, filtrate obtained in two times of extraction is combined, and vacuum concentration is carried out until the density is 1.02-1.08 g/cm3Obtaining concentrated solution of lotus leaves and fructus cannabis for later use.
5. The preparation method of the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying according to claim 3 is characterized by comprising the following steps of:
and b) specifically, adding 180-220L of 85-95 ℃ hot water into a small material tank, stirring, starting the small material tank to circulate, adding xylo-oligosaccharide, stirring for 4-6 minutes, then adding inulin, stirring to completely dissolve the inulin, and then inputting the prepared feed liquid into the material tank.
6. The preparation method of the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying according to claim 3 is characterized by comprising the following steps of:
and d) specifically, adding citric acid and sodium citrate into 8-12L of 85-95 ℃ hot water, stirring to completely dissolve to obtain an acid solution, and adding the acid solution into a batching tank.
7. The preparation method of the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying according to claim 3 is characterized by comprising the following steps of:
the acid solution is added into the batching tank after other raw materials are added into the batching tank.
8. The preparation method of the rice ceramide-containing oral liquid for moisturizing, beautifying, detoxifying and beautifying according to claim 3 is characterized by comprising the following steps of:
the step e) is specifically that the rest of water is added, and the mixture is stirred to uniformly mix the feed liquid; and (5) filling and sterilizing.
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