CN104489462A - Xylooligosaccharide probiotic powder - Google Patents
Xylooligosaccharide probiotic powder Download PDFInfo
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- CN104489462A CN104489462A CN201410748099.3A CN201410748099A CN104489462A CN 104489462 A CN104489462 A CN 104489462A CN 201410748099 A CN201410748099 A CN 201410748099A CN 104489462 A CN104489462 A CN 104489462A
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- 239000000843 powder Substances 0.000 title claims abstract description 76
- HEBKCHPVOIAQTA-NGQZWQHPSA-N d-xylitol Chemical compound OC[C@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-NGQZWQHPSA-N 0.000 title claims abstract description 67
- 239000006041 probiotic Substances 0.000 title claims abstract description 31
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 31
- 230000000529 probiotic effect Effects 0.000 title claims abstract description 25
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims abstract description 29
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/113—Acidophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/21—Streptococcus, lactococcus
- A23V2400/249—Thermophilus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/517—Bifidum
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/533—Longum
Abstract
The invention discloses xylooligosaccharide probiotic powder which is prepared from the following raw materials in parts by weight: 100-1500 parts of xylooligosaccharide, 500-2000 parts of honey powder, 500-2000 parts of sorbitol, 100-1000 parts of konjac glucomannan, 100-700 parts of probiotics, and 500-3000 parts of apple fruit powder, wherein the probiotics are selected from one or more of the bacteria. Due to the combination of the probiotics and prebiotic xylooligosaccharide, the xylooligosaccharide probiotic powder can achieve the physiological effect of the probiotics, and can selectively increase the number of the probiotics, so that the effect of the xylooligosaccharide probiotic powder is more significant and lasting, intestinal floras are balanced, and the intestinal health is improved so as to achieve the purpose of improving constipation for a long time.
Description
Technical field
The invention belongs to technical field of health care food, relate to a kind of xylo-oligosaccharide probiotic powder.
Background technology
In recent years, the incidence of the functional consitipation caused due to factors such as rhythm of life quickening, dietary factor, drug effects constantly raises, particularly city white collar, diet is too meticulous, lack move, often travel on business trips, stress crosses big city and causes constipation.Constipation can make the intensely dark pool of skin form acne, color spot, and cause lassitude, have the fidgets, belly distending pain, prolonged constipation also can cause anus intestines complication, even can cause the carcinoma of the rectum, colon cancer.
At present, in the product that relaxes bowel conventional on market, major part is containing irritant purgatives such as cassia seed, folium sennae, rheum officinale, saltcake, stimulates neuron in intestines wall to cause enterocinesia to increase, although the object of rapid defaecation can be reached, but long-term taking cathartic, easily forms pharmacological dependence, also intestines melanose may be caused, infringement enteric nervous system, the power of colon is weakened, thus increases the weight of constipation, even some medicine is under then bitter cold is rushed down, impairing the spleen and stomach, totally unfavorable to human body.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of xylo-oligosaccharide probiotic powder relaxed bowel, probio is combined with prebiotics xylo-oligosaccharide, both can play the physiological action of probio, optionally increase again the quantity of probio, and make it act on more significantly lasting, balance intestinal flora, improve intestinal health, avoid the defect relaxed bowel existing for product circulated in market, and reach the object improving constipation for a long time.
The present invention is achieved by the following technical solutions:
The xylo-oligosaccharide probiotic powder relaxed bowel is be made up of the raw material of following weight portion: xylo-oligosaccharide 100 ~ 1500 parts, honey powder 500 ~ 2000 parts, sorbierite 500 ~ 2000 parts, konjac glucomannan 100 ~ 1000 parts, probio 100 ~ 700 parts, apple powder 500 ~ 3000 parts.
Further, described probio is selected from least one in bifidobacterium longum, bifidobacterium bifidum, bifidobacterium lactis, streptococcus thermophilus, lactobacillus paraceasi, lactobacillus acidophilus or Lactobacillus rhamnosus.
Preferably, the described xylo-oligosaccharide probiotic powder relaxed bowel, it is be made up of the raw material of following weight portion: xylo-oligosaccharide 800 ~ 1200 parts, honey powder 1200 ~ 1500 parts, sorbierite 1200 ~ 1500 parts, konjac glucomannan 100 ~ 500 parts, probio 200 ~ 400 parts, apple powder 1800 ~ 2000 parts.
Preferably, the described xylo-oligosaccharide probiotic powder relaxed bowel is be made up of the raw material of following weight portion: xylo-oligosaccharide 700 ~ 800 parts, honey powder 800 ~ 900 parts, sorbierite 1500 ~ 1600 parts, konjac glucomannan 100 ~ 300 parts, bifidobacterium longum 40 ~ 60 parts, bifidobacterium bifidum 40 ~ 60 parts, bifidobacterium lactis 40 ~ 60 parts, streptococcus thermophilus 40 ~ 60 parts, lactobacillus paraceasi 40 ~ 60 parts, lactobacillus acidophilus 40 ~ 60 parts, apple powder 500 ~ 3000 parts.
Present invention also offers the preparation method of the above-mentioned xylo-oligosaccharide probiotic powder relaxed bowel, it is characterized in that,
(1) get the raw materials ready: first by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 80 ~ 85 DEG C of dryings 3 ~ 4 hours, make moisture control at <3%, then cross 100 mesh sieves;
(2) weigh: temperature 18 ~ 26 DEG C between control operation, relative humidity <30%, supplementary material is taken: xylo-oligosaccharide 100 ~ 1500 parts by following parts by weight, honey powder 500 ~ 2000 parts, sorbierite 500 ~ 2000 parts, konjac glucomannan 100 ~ 1000 parts, probio 100 ~ 700 parts, apple powder 500 ~ 3000 parts, for subsequent use;
(3) mix: temperature 18 ~ 26 DEG C between control operation, relative humidity <30%, by above-mentioned material Multidirectional motion type mixer mixing 15 ~ 20 minutes, makes to mix, obtain total mixture material, water activity controls within the scope of <0.2; Obtain xylo-oligosaccharide probiotic powder.
The xylo-oligosaccharide probiotic powder that prepared by said method relax bowel.
The application of the above-mentioned xylo-oligosaccharide probiotic powder relaxed bowel in preparation defaecation ease constipation drinks.
The preparation method that present invention also offers a kind of xylo-oligosaccharide probio health products is:
(1) get the raw materials ready: first by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 85 DEG C of dryings about 3 hours, make moisture control at <3%, then cross 100 mesh sieves.
(2) weigh: temperature 18 ~ 26 DEG C between control operation, relative humidity <30%, accurately takes supplementary material needed for formula ratio, for subsequent use.
(3) mix: temperature 18 ~ 26 DEG C between control operation, relative humidity <30%, by above-mentioned material Multidirectional motion type mixer mixing about 20 minutes, makes to mix, obtain total mixture material, water activity controls within the scope of <0.2.
(4) packing: temperature 18 ~ 26 DEG C between control operation, relative humidity less than 30%, uses automatic nitrogen-charging packing machine to carry out nitrogen-filled packaging in total mixture material.
(5) check: by enterprise's mark requirement, sampling Detection is carried out to sample, require xylo-oligosaccharide content>=18g/100g in sample, probio content>=10
, 10cfu/100g.Whether sample for reference packaging is complete, whether has gas leak phenomenon.
(6) packaging warehouse-in: external packing, vanning will be carried out by packing specification by product after the assay was approved.Be placed in by packaged product in shady and cool dry warehouse, Ku Wen is not higher than 25 DEG C, and relative humidity is not higher than 75%.
Xylo-oligosaccharide probio health products of the present invention, when taking, dissolve by less than 50 DEG C warm waters and take after mixing it with water.
Xylo-oligosaccharide probio health products of the present invention, take after meal half an hour.
Xylo-oligosaccharide probio health products of the present invention, in formula the pharmacology of each raw material and drug effect as follows:
Xylo-oligosaccharide is one of functional oligose that Bifidobacterium cultivation effect is best in human body intestinal canal up to now, is described as " super bifidobacterium ".The SCFA that bifidobacteria metabolize xylo-oligosaccharide produces, can reduce gut pH, while the breeding of other harmful bacterias of suppression, can also promote intestines peristalsis, increase ight soil wettability, promote defecation, prevent the generation of constipation.Xylo-oligosaccharide or a kind of bidirectional modulation agent, also have certain effect to alleviation symptom of diarrhea.
Sorbierite can be produced by Reduction of Glucose, it is a kind of nutritive sweeteners, absorbed lentamente in vivo, and blood glucose value not increasing, is reasonable NMF and interfacial agent, the height utilizing sorbierite to bring oozes effect, allow more moisture infiltrate enteric cavity, softening stool, stimulates intestines wall, cause defecation to react to reflectivity, reach the effect of relief of constipation.
Clinical practice proves, honey has good purging and intestine lubricating action, it is good laxative, can be used as a kind of comparatively ideal medicine, be the jinx for the treatment of habitual constipation, atonic constipation and pregnant woman constipation etc., have obvious facilitation to Small intestine advance activity, and significantly shorten the defaecation time, honey powder had both remained the nutritional labeling of honey, was convenient to processing and utilization again.
The main component of konjac glucomannan is Glucomannan.Glucomannan is solubility hemicellulose, can absorb water, water conservation, and increases faecal volume and mellowness by glycolysis, is beneficial to defaecation, prevents constipation.Glucomannan is again a kind of natural plant gum, can water holding thickening, increases the stability of product.
Functional consitipation is general closely related with intestinal bacilli illness, supplements the beneficial bacteria of intestinal tract such as Bifidobacterium, recovers gut flora and balances, can relief of constipation effectively.The acetic acid that bifidobacteria metabolize produces and lactic acid pH value are 2.8 ~ 3.1, make enteron aisle be acid, can control by harmful microbial abnormal fermentation, reduce the generation of toxic metabolic products, and stimulate enterocinesia, thus reduce the taken in excess of moisture and relief of constipation symptom.
Lactobacillus has acidproof, that acid producing ability is strong feature, and, suppression small bowel bacterial overgrowth active by antagonism harmful microorganism carrys out regulating intestinal canal flora, has and maintains intestinal flora balance, improve the several functions such as immunity of organisms.
Apple contains abundant dietary fiber-pectin, and the pectin in apple can absorb the moisture of volume 2.5 times own, can increase faecal volume softer stool, promotes intestines peristalsis, plays the effect relaxed bowel.
Xylo-oligosaccharide probio health products of the present invention, use beneficial bacteria of intestinal tract and prebiotics xylo-oligosaccharide, intestine microenvironment can be improved, also added honey powder, sorbierite, konjac glucomannan, apple powder in addition, possesses the function of probiotics, demulcent cathartics, permeability purgatives, bulk-forming laxative simultaneously, and can not have side effects, the object of long-term Constipation can be reached.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1 prepares xylo-oligosaccharide probio health products
Formula is: xylo-oligosaccharide 800 grams, honey powder 1200 grams, sorbierite 800 grams, konjac glucomannan 100 grams, bifidobacterium bifidum (1,000 hundred million/gram) 40 grams, bifidobacterium lactis (1,000 hundred million/gram) 40 grams, lactobacillus paraceasi (1,000 hundred million/gram) 60 grams, lactobacillus acidophilus (1,000 hundred million/gram) 60 grams, apple powder 2000 grams.
Preparation method is:
First by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 85 DEG C of dryings about 3 hours, moisture is made to control at <3%, then 100 mesh sieves are crossed, accurately take supplementary material needed for formula ratio, raw material is mixed, then automatic nitrogen-charging packaging 5g/ bag is carried out, temperature 18 ~ 26 DEG C between operating process control operation, relative humidity <30%.
Dissolve by less than 50 DEG C warm waters when taking and take after mixing it with water.
Embodiment 2 prepares xylo-oligosaccharide probio health products
Formula is: xylo-oligosaccharide 1000 grams, honey powder 1000 grams, sorbierite 1000 grams, konjac glucomannan 150 grams, bifidobacterium longum (1,000 hundred million/gram) 50 grams, bifidobacterium bifidum (1,000 hundred million/gram) 50 grams, lactobacillus acidophilus (10,000,000,000/gram) 50 grams, streptococcus thermophilus (10,000,000,000/gram) 50 grams, apple powder 1800 grams.
Preparation method is:
First by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 85 DEG C of dryings about 3 hours, moisture is made to control at <3%, then 100 mesh sieves are crossed, accurately take supplementary material needed for formula ratio, raw material is mixed, then automatic nitrogen-charging packaging 5g/ bag is carried out, temperature 18 ~ 26 DEG C between operating process control operation, relative humidity <30%.
Dissolve by less than 50 DEG C warm waters when taking and take after mixing it with water.
Embodiment 3 prepares xylo-oligosaccharide probio health products
Formula is: xylo-oligosaccharide 1200 grams, honey powder 800 grams, sorbierite 1200 grams, konjac glucomannan 200 grams, bifidobacterium longum (1,000 hundred million/gram) 60 grams, bifidobacterium lactis (1,000 hundred million/gram) 60 grams, lactobacillus paraceasi (1,000 hundred million/gram) 40 grams, streptococcus thermophilus (1,000 hundred million/gram) 40 grams, apple powder 1600 grams.
Preparation method is:
First by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 85 DEG C of dryings about 3 hours, moisture is made to control at <3%, then 100 mesh sieves are crossed, accurately take supplementary material needed for formula ratio, raw material is mixed, then automatic nitrogen-charging packaging 5g/ bag is carried out, temperature 18 ~ 26 DEG C between operating process control operation, relative humidity <30%.
Embodiment 4 prepares xylo-oligosaccharide probio health products
Formula is: xylo-oligosaccharide 750 grams, honey powder 850 grams, sorbierite 1500 grams, konjac glucomannan 180 grams, bifidobacterium longum (1,000 hundred million/gram) 45 grams, bifidobacterium bifidum (1,000 hundred million/gram) 45 grams, bifidobacterium lactis (1,000 hundred million/gram) 45 grams, streptococcus thermophilus (1,000 hundred million/gram) 60 grams, lactobacillus paraceasi (1,000 hundred million/gram) 60 grams, lactobacillus acidophilus (1,000 hundred million/gram) 60 grams, apple powder 1500 grams.
Preparation method is:
First by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 85 DEG C of dryings about 3 hours, moisture is made to control at <3%, then 100 mesh sieves are crossed, accurately take supplementary material needed for formula ratio, raw material is mixed, then automatic nitrogen-charging packaging 5g/ bag is carried out, temperature 18 ~ 26 DEG C between operating process control operation, relative humidity <30%.
Embodiment 5 prepares xylo-oligosaccharide probio health products
Formula is: xylo-oligosaccharide 700 grams, honey powder 800 grams, sorbierite 1500 grams, konjac glucomannan 220 grams, bifidobacterium longum (1,000 hundred million/gram) 60 grams, bifidobacterium bifidum (1,000 hundred million/gram) 60 grams, bifidobacterium lactis (1,000 hundred million/gram) 40 grams, streptococcus thermophilus (1,000 hundred million/gram) 50 grams, lactobacillus paraceasi (1,000 hundred million/gram) 50 grams, lactobacillus acidophilus (1,000 hundred million/gram) 50 grams, apple powder 1700 grams.
Preparation method is:
First by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 85 DEG C of dryings about 3 hours, moisture is made to control at <3%, then 100 mesh sieves are crossed, accurately take supplementary material needed for formula ratio, raw material is mixed, then automatic nitrogen-charging packaging 5g/ bag is carried out, temperature 18 ~ 26 DEG C between operating process control operation, relative humidity <30%.
Embodiment 6 prepares xylo-oligosaccharide probio health products
Formula is: xylo-oligosaccharide 800 grams, honey powder 890 grams, sorbierite 1600 grams, konjac glucomannan 160 grams, bifidobacterium longum (1,000 hundred million/gram) 50 grams, bifidobacterium bifidum (1,000 hundred million/gram) 50 grams, bifidobacterium lactis (1,000 hundred million/gram) 50 grams, streptococcus thermophilus (1,000 hundred million/gram) 40 grams, lactobacillus paraceasi (1,000 hundred million/gram) 60 grams, Lactobacillus rhamnosus (1,000 hundred million/gram) 60 grams, apple powder 1200 grams.
Preparation method is:
First by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 85 DEG C of dryings about 3 hours, moisture is made to control at <3%, then 100 mesh sieves are crossed, accurately take supplementary material needed for formula ratio, raw material is mixed, then automatic nitrogen-charging packaging 5g/ bag is carried out, temperature 18 ~ 26 DEG C between operating process control operation, relative humidity <30%.
Dissolve by less than 50 DEG C warm waters when taking and take after mixing it with water.
Case-data: clinical practice 100 example, women 62 example, 22 ~ 50 years old age, the male sex 38 example, 25 ~ 48 years old age, 35 years old mean age.Three days non-defecation person 34 examples, 4 days non-defecation person 38 examples, 5 days non-defecation person 26 examples, 7 days non-defecation person 2 examples.The all inactive various charthartic of patient before treatment.
Methods for the treatment of: the medicine of embodiment of taking after mixing it with water 3, once a day, each potion (dosage that embodiment 3 provides is the amount of potion) two weeks is a course for the treatment of.
Therapeutic evaluation:
Effective: clinical symptom disappearance, stool once a day, stablizes two weeks.
Effective: clinical symptoms substantially disappear or are clearly better, the normal or number of times of defecating obviously increases.
Invalid: symptom or times of defecation are not improved.
Treatment results: 100 routine constipation persons, effective 71 examples, effective 22 examples, invalid 7 examples, obvious effective rate 71%, total effective rate 93%, does not all find toxic and side effect, and patient easily accepts.
Clinical model case:
Case 1: Chen, female, 20 years old, student enrollment, because of lack exercise and learning pressure excessive, frequent constipation, show as stool stiff, even one week defecation once, the dim Huang of face, belly distending pain, take the xylo-oligosaccharide probiotic powder health products of embodiment 4 after 5 days, somatosensory is light, and constipation is eased, continue to take two weeks, defecation is normal.
Case 2: Lee, man, 31 years old, be engaged in IT industry and be sitting in the time before computer more than 12 hours every day, motion is few, and operating pressure is large, prolonged constipation, have the fidgets, with crossing cathartic, take the xylo-oligosaccharide probiotic powder health products of embodiment 5 after one week, defecation frequency significantly increases, after adhering to taking one month, symptom is eliminated substantially.
Case 3: Wang, female, 45 years old, clerk, initial just slight constipation, namely alleviates after taking constipation-relieving tea to some extent, but find that constipation increases the weight of all the more after taking defaecation product for a long time, final charthartic is invalid, often suffers from abdominal pain unbearably, takes the xylo-oligosaccharide probiotic powder health products of embodiment 6, after about two weeks, constipation symptom improves, and after adhering to taking one month, symptom is eliminated substantially.
The xylo-oligosaccharide probiotic powder sense organ evaluating meter that table 1 relaxes bowel
Note: sensory evaluation is 10 people group evaluation results
Although above-mentioned, the specific embodiment of the present invention is described; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendment or distortion that creative work can make still within protection scope of the present invention.
Claims (6)
1. the xylo-oligosaccharide probiotic powder relaxed bowel, it is characterized in that, it is be made up of the raw material of following weight portion: xylo-oligosaccharide 100 ~ 1500 parts, honey powder 500 ~ 2000 parts, sorbierite 500 ~ 2000 parts, konjac glucomannan 100 ~ 1000 parts, probio 100 ~ 700 parts, apple powder 500 ~ 3000 parts.
2. the xylo-oligosaccharide probiotic powder relaxed bowel as claimed in claim 1, it is characterized in that, described probio is selected from least one in bifidobacterium longum, bifidobacterium bifidum, bifidobacterium lactis, streptococcus thermophilus, lactobacillus paraceasi, lactobacillus acidophilus or Lactobacillus rhamnosus.
3. the xylo-oligosaccharide probiotic powder relaxed bowel as claimed in claim 1, it is characterized in that, it is be made up of the raw material of following weight portion: xylo-oligosaccharide 800 ~ 1200 parts, honey powder 1200 ~ 1500 parts, sorbierite 1200 ~ 1500 parts, konjac glucomannan 100 ~ 500 parts, probio 200 ~ 400 parts, apple powder 1800 ~ 2000 parts.
4. the xylo-oligosaccharide probiotic powder relaxed bowel as claimed in claim 1, is characterized in that, is to be made up of the raw material of following weight portion: xylo-oligosaccharide 700 ~ 800 parts, honey powder 800 ~ 900 parts, sorbierite 1500 ~ 1600 parts, konjac glucomannan 100 ~ 300 parts, bifidobacterium longum 40 ~ 60 parts, bifidobacterium bifidum 40 ~ 60 parts, bifidobacterium lactis 40 ~ 60 parts, streptococcus thermophilus 40 ~ 60 parts, lactobacillus paraceasi 40 ~ 60 parts, lactobacillus acidophilus 40 ~ 60 parts, apple powder 500 ~ 3000 parts.
5. a preparation method for the xylo-oligosaccharide probiotic powder relaxed bowel, is characterized in that,
(1) get the raw materials ready: first by xylo-oligosaccharide, honey powder, sorbierite, konjac glucomannan, apple powder in 80 ~ 85 DEG C of dryings 3 ~ 4 hours, make moisture control at <3%, then cross 100 mesh sieves;
(2) weigh: temperature 18 ~ 26 DEG C between control operation, relative humidity <30%, supplementary material is taken: xylo-oligosaccharide 100 ~ 1500 parts by following parts by weight, honey powder 500 ~ 2000 parts, sorbierite 500 ~ 2000 parts, konjac glucomannan 100 ~ 1000 parts, probio 100 ~ 700 parts, apple powder 500 ~ 3000 parts, for subsequent use;
(3) mix: temperature 18 ~ 26 DEG C between control operation, relative humidity <30%, by above-mentioned material Multidirectional motion type mixer mixing 15 ~ 20 minutes, makes to mix, obtain total mixture material, water activity controls within the scope of <0.2; Obtain xylo-oligosaccharide probio to relax bowel probiotic powder.
6. the application of the xylo-oligosaccharide probiotic powder relaxed bowel described in claim 1 or 2 in preparation defaecation ease constipation drinks.
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| CN106616586A (en) * | 2016-10-14 | 2017-05-10 | 千亿达（天津）科技有限公司 | Health-care probiotics powder for intestines and stomachs |
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| CN106616586A (en) * | 2016-10-14 | 2017-05-10 | 千亿达（天津）科技有限公司 | Health-care probiotics powder for intestines and stomachs |
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| CN109497484A (en) * | 2018-10-10 | 2019-03-22 | 广东科贸职业学院 | A kind of preparation method of the solid honey ball containing profitable probliotics |
| CN109497484B (en) * | 2018-10-10 | 2021-05-11 | 广东科贸职业学院 | Preparation method of solid bee honey pills containing probiotics |
| CN113713080A (en) * | 2021-07-09 | 2021-11-30 | 武汉自然萃创新科技有限公司 | Probiotic honey dew |
| WO2023155714A1 (en) * | 2022-02-21 | 2023-08-24 | 美慕(北京)科技有限公司 | Microbial composition, method for preparing same, and use thereof |
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