CN104223074A

CN104223074A - Total-nutrition formula food for preventing constipation

Info

Publication number: CN104223074A
Application number: CN201410473824.0A
Authority: CN
Inventors: 胡安然
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-09-17
Filing date: 2014-09-17
Publication date: 2014-12-24

Abstract

The invention provides total-nutrition formula food for a patient with constipation, and relates to specific total-nutrition formula food or non-total-nutrition formula food. According to requirements of general rules of formula food for specific medical purposes and physical characteristics of the patient with constipation, various medicinal and edible Chinese herb extract essences which are extracted with a prehydrolysis SBE technology , various microencapsulated probiotics, oligopeptide extracted through biological enzymolysis, prebiotics, amino acid, poria cocos, puerarin roots, carbohydrate, multiple vitamins and mineral substances are adopted in the formula food to be smashed and mixed to prepare the food. The food not only can be taken as a single nutrition source to meet the nutritional requirement of the patient with constipation, but also has the functions of loosening the bowel to relieve constipation, nourishing yin to moisten dryness, nourishing liver and kidney, clearing heat, removing food retention, removing food stagnation, facilitating feces excretion, relieving internal heat or fever, lubricating intestines and preventing constipation.

Description

The full nutritional formulas of constipation

Technical field

The invention belongs to integration of drinking and medicinal herbs class formula and food technology field, specifically the Traditional Chinese Medicine marrow of " Chinese medicine of integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds the full nutritional formulas of constipation, specific full nutritional formulas or the non-fully nutritional formulas made for auxiliary material with small peptide, prebiotics, amino acid, carbohydrate, B B-complex, composite mineral matter.

Background technology

Constipation is one of comparatively common modern sub-health state, and be mainly in the gastrointestinal function imbalance persons such as the brain worker of sitting of bending over the desk, student, the traditional Chinese medical science thinks that constipation belongs to the result of large functional disorder of intestine, mainly contains following several respects.(1) insufficiency of the spleen mistake fortune, this is the most common interpretation of the cause, onset and process of an illness of constipation, lose if insufficiency of the spleen in transporting, the duty being then elevated discrepancy is uncomfortable, show as constipation with insufficiency of the spleen disease, stool is how first dry rear soft, defecate not smooth, defecation inability, within many days, do not defecate almost bitter without institute yet, this kind of is comparatively common, many by improper diet, sitting lacks the bad life habits such as motion and causes, (2) sthenia gastropyrexia, stomach, intestine and small intestine all dependent territory is dirty, though the main department of large intestine weeds out the old and bring forth the new, conduction waste matter, but its gas led by the logical effect of falling of stomach Qi, stomach intestine and small intestine is real to be integrated, the stomach channel of foot-Yang-ming walk the positive side of human body through up and down inside and outside, that people's body atmosphere led, stomach Qi is suitable to reduce to, to reduce to benefit, effect imbalance falls in Ruo Qitong, inside accumulate heat-transmission and then occur that stomach is through excessive heat syndrome, show as constipation, anus dryness and heat, the red arteries and veins number of halitosis dry tongue etc., (3) to suffer from a deficiency of the kidney constipation, the kidney controlling urination and defecation, front and back two the moon all led by kidney, kidney is the pass of stomach, under physiological condition, the nourishing of kidney essense is the basis that large intestine keeps smart Tianjin moist, the temperature effect of leading to of kidney qi is the power keeping smart Tianjin spreading, therefore pungently to moisturize, kidney essense negative and positive vigour ensure that two just normal in the normal gasification of the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, if kidney essence deficiency, negative and positive gasification is not normal, cloth and dry and astringent not smooth is lost in large intestine essence Tianjin, this constipation belongs to person who suffer from deficiency of kidney Yang, (4) lung qi closing, the lung and the large intestine being interior-exteriorly related, main a surname of lung qi sends out prompt drop and belongs to dirty for cloudy, the main excretion waste matter of large intestine belongs to FU-organs belonging to YANG, cloudy rise sun to fall this physiology often.If the exterior tightened by exogenous pathogens, lung qi loses in a surname logical, and cause internal organs gas to lead to and fall, just there will be the momentary constipation of dry and hard excrement, " integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science; The traditional Chinese medical science is always emphasized " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet; Allow people dispel slight illness in the process enjoying cuisines, avoid and have an injection, take medicine, even pain of surgery.

For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And the full nutritional formulas of wholefood clear stipulaties: 2.1.1 in China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 specific full nutritional formulas: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition.

Traditional Chinese medical science traditional medicine is thought: " spleen (i.e. digestive system) is the foundation of acquired constitution ", and stomach health is healthy basis, and 99% of human nutrition needs by intestinal absorption, and intestinal bowel disease is also the source of ten thousand diseases; But along with the age is larger, in enteron aisle, profitable strain (probio) ratio reduces gradually; As Bifidobacterium Bifidum accounts for 98% infant period, be down to 10% to during the middle age, within 65 years old, only account for 5% later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies display, normal flora human consumption, immunity and disease-resistant etc. in have many irreplaceable effects; The change of gut flora composition and the generation of various diseases, particularly intestines problem develop closely related, and find from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one intervenes control method safely and effectively.

The relation of constipation and gut flora: constipation is a kind of illness, through investigation, constipation is a kind of quite general illness, have the men and women of significant proportion all to live through constipation, cause the factor of constipation a lot, wherein gut flora is a very important factor, healthy enteron aisle is the gut flora interwoveness useful with the inside, under healthiness condition, the beneficial bacterium in intestinal flora is preponderated, and its representative is as Bifidobacterium, lactobacillus etc.Such as, Bifidobacterium, it has important function in the normal intestines peristalsis of maintenance, because Bifidobacterium and other obligate anaerobic bacterium have product acid function, it can make to be in a sour environment in enteric cavity, there is regulating intestinal canal normal creepage of gastrointestinal functions, maintain the effect of physiological function, if when intestinal bifidobacteria lacks, the wriggling function of enteron aisle reduces, ight soil in enteric cavity just not easily excretes, cause constipation, long-term constipation can make harmful substance repetitious stimulation intestines walls a large amount of in ight soil, just likely produce the carcinoma of the rectum, normal fecal stools contains the moisture content of 70-80%, the maintenance of these moisture content just has benefited from attachment and the existence of intestinal flora, so maintain the health of health, in maintenance intestines, beneficial bacterium is preponderated is very necessary, so, long-term habits constipation is not Normal appearances, should attach the importance.

Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter composition compound prescription, utilize the product that probio is primary raw material in addition, but also do not find the constitutive character in conjunction with constipation patient, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials is the full nutritional formulas that auxiliary material is made, specific full nutritional formulas or similar products.

goal of the invention

The object of the invention is on the theoretical treatment method of succession traditional Chinese medical science marrow, the initiative extract by the probio of multiple raising body immunity and " Chinese medicine of integration of drinking and medicinal herbs " compound combines, add with small peptide, amino acid, carbohydrate, multivitamin, several mineral materials is auxiliary material, constipation patient institute essential nutrients can not only be supplemented, improve body nutrition condition, can also and utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutritional formulas that the acceptable applicable constipation patient of people is edible, specific full nutritional formulas or non-fully nutritional formulas.

summary of the invention:

This R&D team is according to the requirement of " special medicine purposes formula food general rule ", in conjunction with the constitutive character of constipation patient, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears benefit ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt the Chinese medical extract elite of two or more medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets constipation patient, relax bowel in addition, nourishing yin to moisten dryness, nourishing liver and kidney, heat-clearing disappears long-pending, lead stagnant defaecation, the full nutritional formulas of removing toxic substances laxation and anti-effect treated constipation, specific full nutritional formulas or non-fully nutritional formulas (compound prescription be combined into).

1, the main component of the present invention's formula is:

Chinese medical extract is dirty with being adjusted to main principle from the liver,spleen,kidney three theory of traditional Chinese medical science according to the constitutive character of constipation patient, utilizes the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and chooses following several large class medicine and carry out compatibility, wherein: folium sennae is purged heat capable stagnant, defaecation, Li Shui, stagnate for thermojunction, constipation is suffered from abdominal pain, oedema turgor, stem of noble dendrobium reinforcing stomach reg fluid, nourishing Yin and clearing heat, rhubarb major function is stasis removing, relieving constipation by purgation, stagnate for Gastrointestinal excess heat, constipation, plantain seed Li Shui, heat-clearing, improving eyesight, eliminate the phlegm, the beneficial spleen qi-restoratives of fructus cannabis energy, nourishing yin to moisten dryness, defaecation, brush-cherry seed has moisturizes laxation, lower gas is capable stagnant, effect of inducing diuresis for removing edema, perillaseed droping gas dissolving phlegm, relieving cough and asthma, relax bowel, sterculia seed heat-clearing, moistening lung, relieve sore throat, removing toxic substances, dandelion is clearing heat and detoxicating, diuresis dissipating bind, cassia seed has clearing away the liver-fire, wines used as antirheumatic, tonifying kidney and improving eyesight, the effect such as relax bowel, konjaku konjaku is cold in nature, pungent, poisonous, can be promoting blood circulation and removing blood stasis, removing toxicity for detumescence, wide intestines defaecation, resolving phlegm and softening hard masses, lily Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, radix polygonati officinalis yin-nourishing, moisturizes, and relieving restlessness is quenched the thirst,

Medicinal and edible Chinese medicine extract of the present invention refers to the stem of noble dendrobium, folium sennae, rhubarb, the Radix Astragali, plantain seed, Cordyceps militaris, fructus cannabis, brush-cherry seed, perillaseed, the sterculia seed, dandelion, Radix Glycyrrhizae, cassia seed, radish seed, lily, radix polygonati officinalis, aloe, orange peel, hawthorn, mulberry fruit, dried orange peel, almond, Chinese yam, dark plum, sea-buckthorn, Momordica grosvenori, peach kernel, sealwort, rde bean, konjaku Fructus Hordei Germinatus, cordate houttuynia, honeysuckle, spirulina, dietary fiber, yeast wherein two or more or all, biological enzymolysis or prehydrolysis SBE is adopted to extract and microencapsulation, mixture after spray-dried and cryodesiccated extract.

2, multiple probio: make probio major part can arrive enteron aisle by the strong acid environment of stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote the absorption to trace element, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, obviously can reduce the level of intestinal endotoxemia and the generation of preventing liver injury; Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by urease-producing in suppression enteron aisle and the growth of producing ammonium bacteria, builds up resistance;

Multiple probio of the present invention all adopts the probio after microencapsulation, except streptococcus thermophilus, wherein Bifidobacterium: refer to that bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum are wherein a kind of, several or all mix; Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus are wherein a kind of, several or all mix.

3, small peptide: be oligopeptide, refer to the small molecule protein utilizing bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is at below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need directly to absorb through digestion, bioavailability is high, absorbing and utilizing the amino acid and complete protein that are better than dissociating, can be applicable in Protein intake food, especially for the crowd that abilities of digestive and absorption is low, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function improving small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,

Small peptide of the present invention refers to that marine collagen peptide, wheat oligopeptide, maize oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.

4. prebiotics: with short probio intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most enteron aisle spoilage organisms, but beneficial bacteria in human body can be promoted---the growth and breeding of lactobacillus, Bifidobacterium, thus spoilage organisms can be suppressed to grow, contribute to improving and maintaining enteron aisle normal function; Long-term edible can to delay senility, defaecation, raising immunity, the absorptivity that alleviates burden of liver, improve nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, knot intestinal pH is reduced, suppresses the growth of intestinal harmful bacillus; Water-Electrolyte in small intestine is made to be trapped in enteric cavity, produce and highly ooze effect, stimulate enterocinesia to cause laxative, thus promote the discharge of intestinal endotoxin and other toxicants, lactulose also can directly endotoxin in deactivation enteron aisle, reduce gut pH, extensively model is applied to the treatment of enhancing child resistant;

Prebiotics of the present invention is 2 classes

A. very strong field planting effect prebiotics is had to external source probio: the extract of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, stachyose, yeast wherein several or all mix;

B. common prebiotics: oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix;

Originally oligoisomaltose, stachyose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix is referred to.

5, carbohydrate: carbohydrate is by carbon, hydrogen and oxygen three kinds of element compositions, it is for human body provides nutrient the most cheap in three of heat energy kinds of main nutrients, when taking in sufficient, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,

Carbohydrate of the present invention refers to glucose, fructose, galactolipin, lactose, Arabinose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

6. amino acid: be divided into essential amino acid and nonessential amino acid, is the base unit forming protein, gives protein specific molecular morphosis, make it have biochemical activity; Absorb appropriate methionine and contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances; Leucine can repair muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress cancer growth, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to changing the ammonia in blood into urea and excreting out; For hyperammonemia, hepatic dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses nervous by vegetative nerve and alimentary canal that is that cause festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improving water flood and adjustment mood;

Amino acid of the present invention refers to Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

7. vitamin and mineral matter:

Vitamin and mineral matter are the nutrients of needed by human, the nutrient of the vitamin added in the present invention to be vitamin and mineral matter be needed by human;

The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix;

The mineral matter added in the present invention is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;

In the present invention, the addition of vitamin and minerals is with reference to GB14880 " food enrichment use sanitary standard ", GB2760 " food additives use standard " performs, now for 1000g finished product, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

8. the present invention is with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent treating constipation significantly improves compared with the like product of market.

9. adopt above-mentioned integrated innovation technique various batching to be mixed solid beverage, the granule of making powdery, and be distributed into 10g/ bag, with about 150ml, 45 degree of warm waters are directly drunk or are taken in through nasal feeding after dissolving; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

The characteristic of this full nutritional formulas of filling a prescription and the following aspects is mainly manifested in the effect of body:

1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with the constitutive character of constipation patient, the achievement in research developments such as the advanced physiology of comprehensive nowadays American Harvard University, medicine, nutrition and clinical practice, vary with each individual, gold compatibility.

2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is adopted to be primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter for auxiliary material, the organic assembling of various batching, various function is merged, and by the synergy between active ingredient, humidification effect.

3. have effective absorbency, utilize formula of the present invention, various component adopts the food of suitable ratio collocation preparation, in isotonic state after a certain amount of water-soluble solution, small intestine can be arrived quickly through stomach, absorb fast, completely, constipation patient desired nutritional can be supplemented rapidly.

4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicine, containing several functions active component, not only increase the concentration of function factor, reduce the absorption of various impurity, contribute to alleviating liver kidney burden, have and strengthen the effect of resistance of human body, relax bowel in addition, nourishing yin to moisten dryness, nourishing liver and kidney, heat-clearing disappear long-pending, lead stagnant defaecation, removing toxic substances laxation and anti-effect treated constipation.

5. probio contained in the present invention's formula, multiple probio can safeguard enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and raising body are to the absorption of calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve host to the tolerance of radioactive ray, lactobacillus significantly increases intestinal mucosal immune globulin A (SIgA) content, to body intestinal mucosa local immunity, there is regulating action, regulate stomach, intestines Tiny ecosystem, calcium can be improved, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, the absorption of cholesterol can also be reduced.

6. formula food of the present invention with the food source property bioactive short peptide in multiple source for nitrogenous source, because small peptide does not need digestion and Absorbable rod, more be conducive to the utilization of body, can effectively improve constipation patient negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, improves the absorbability of intestinal mucosa.

7. this prescription have employed this team by over nearly 3 year to the achievement that the key technology of probio field planting mechanism in enteron aisle is studied, improve " Chinese medicine of integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence combining prebiotics can play the key elements such as field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula greatly strengthen the field planting effect to external source probio.

8. prebiotics contained in the present invention's formula; by promoting the growth and breeding of probio in intestines; suppress the growth of spoilage organisms; form one protective barrier at intestinal mucosal surface simultaneously; the damage of enteron aisle spoilage organisms to intestinal mucosa can be resisted; reduce the absorption of intestinal toxic material; intestines peristalsis can also be promoted; accelerate the discharge of residuals in intestines; constipation can be prevented; and by promoting that the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy.

9, in the present invention's formula, contained carbohydrate is for human body provides three of heat energy kinds of main nutrients, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce.

10, contained in the present invention's formula amino acid, it is the base unit forming protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances, muscle can be repaired, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development.

11, formula food of the present invention is containing multivitamin and mineral matter, can supplement rapidly the micronutrient needed for constipation patient, small peptide by with the chelating of calcium, iron, zinc etc. after, further increase the absorptivity of mineral matter element.

12, not fatty and cholesterol in the present invention's formula, while supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, avoid the adverse effect of the high protein diet such as meat, egg.

Detailed description of the invention

Below by following examples, the invention will be further described, and it will contribute to understanding the present invention.

Embodiment one

Realizing the full nutritional formulas of the object of the invention constipation is constitutive character in conjunction with constipation patient, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with the Chinese medical extract elite of two or more medicine-food two-purpose, multiple probio, small peptide for primary raw material, the food made for auxiliary material with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;

Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose: stem of noble dendrobium 14g, folium sennae 14g, rhubarb 14g, Radix Astragali 12g, plantain seed 12g, Cordyceps militaris 12g, fructus cannabis 12g, brush-cherry seed 12g, perillaseed 12g, sterculia seed 10g, dandelion 10g, Radix Glycyrrhizae 10g, cassia seed 10g, radish seed 10g, lily 10g, radix polygonati officinalis 10g, aloe 8g, orange peel 8g, hawthorn 8g, mulberry fruit 8g, dried orange peel 8g, almond 8g, Chinese yam 8g, dark plum 8g, sea-buckthorn 6g, Momordica grosvenori 6g, peach kernel 6g, sealwort 6g, rde bean 6g, konjaku 6g, Fructus Hordei Germinatus 6g, cordate houttuynia 6g, honeysuckle 4g, spirulina 4g, dietary fiber 4g, yeast 4g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 100g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

First will to be the stem of noble dendrobium during making, folium sennae, rhubarb, the Radix Astragali, plantain seed, fructus cannabis, brush-cherry seed, perillaseed, the sterculia seed, dandelion, Radix Glycyrrhizae, cassia seed, radish seed, lily, radix polygonati officinalis, aloe, orange peel, hawthorn, mulberry fruit, dried orange peel, dark plum, sea-buckthorn, Momordica grosvenori, sealwort, cordate houttuynia, honeysuckle, the membrane of a chicken's gizzard, Chinese yam, Gorgon fruit soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid, rde bean, konjaku, Fructus Hordei Germinatus, spirulina, dietary fiber, yeast, coix seed, almond, Cordyceps militaris, carbohydrate, peach kernel, carry out pasteurization after multivitamin and mineral matter are pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, with about 150ml, 45 degree of warm waters are directly drunk or are taken in through nasal feeding after dissolving, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

Embodiment two

The full nutritional formulas of above-mentioned constipation also comprises following component by weight: the extract of medicine-food two-purpose: fructus cannabis 10g, brush-cherry seed 10g, Cordyceps militaris 10g, perillaseed 10g, sterculia seed 10g, dandelion 10g, Radix Glycyrrhizae 8g, cassia seed 8g, radish seed 8g, lily 8g, radix polygonati officinalis 8g, aloe 8g, orange peel 8g, hawthorn 6g, mulberry fruit 6g, dried orange peel 6g, almond 6g, Chinese yam 6g, dark plum 6g, sea-buckthorn 6g, Momordica grosvenori 6g, peach kernel 6g, sealwort 4g, rde bean 4g, Fructus Hordei Germinatus 4g, cordate houttuynia 4g, honeysuckle 4g, spirulina 2g, konjaku 2g, dietary fiber 2g, yeast 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

Embodiment three

The full nutritional formulas of above-mentioned constipation also comprises following component by weight: the extract of medicine-food two-purpose: fructus cannabis 10g, brush-cherry seed 10g, Cordyceps militaris 10g, perillaseed 10g, sterculia seed 10g, dandelion 10g, Radix Glycyrrhizae 8g, cassia seed 8g, radish seed 8g, lily 8g, radix polygonati officinalis 8g, aloe 8g, orange peel 8g, hawthorn 6g, mulberry fruit 6g, dried orange peel 6g, almond 6g, Chinese yam 6g, dark plum 6g, sea-buckthorn 6g, Momordica grosvenori 6g, peach kernel 6g, sealwort 4g, rde bean 4g, Fructus Hordei Germinatus 4g, cordate houttuynia 4g, honeysuckle 4g, spirulina 2g, konjaku 2g, dietary fiber 2g, yeast 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 150g, carbohydrate 100g.

The present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent treating constipation significantly improves compared with the like product of market.

Claims

1. the full nutritional formulas of constipation, it is characterized in that the constitutive character in conjunction with constipation patient, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with the Chinese medical extract elite of two or more medicine-food two-purpose, multiple probio, small peptide for primary raw material, the food made for auxiliary material with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;

Its preparation method is first by the stem of noble dendrobium, folium sennae, rhubarb, the Radix Astragali, plantain seed, fructus cannabis, brush-cherry seed, perillaseed, the sterculia seed, dandelion, Radix Glycyrrhizae, cassia seed, radish seed, lily, radix polygonati officinalis, aloe, orange peel, hawthorn, mulberry fruit, dried orange peel, dark plum, sea-buckthorn, Momordica grosvenori, sealwort, cordate houttuynia, honeysuckle, the membrane of a chicken's gizzard, Chinese yam, Gorgon fruit soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid, rde bean, konjaku, Fructus Hordei Germinatus, spirulina, dietary fiber, yeast, coix seed, almond, Cordyceps militaris, carbohydrate, peach kernel, carry out pasteurization after multivitamin and mineral matter are pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, with about 150ml, 45 degree of warm waters are directly drunk or are taken in through nasal feeding after dissolving, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.

2. the full nutritional formulas formula of constipation according to claim 1, it is characterized in that described medicine-food two-purpose Chinese herbal medicine extract is: the stem of noble dendrobium, folium sennae, rhubarb, the Radix Astragali, plantain seed, Cordyceps militaris, fructus cannabis, brush-cherry seed, perillaseed, the sterculia seed, dandelion, Radix Glycyrrhizae, cassia seed, radish seed, lily, radix polygonati officinalis, aloe, orange peel, hawthorn, mulberry fruit, dried orange peel, almond, Chinese yam, dark plum, sea-buckthorn, Momordica grosvenori, peach kernel, sealwort, rde bean, konjaku Fructus Hordei Germinatus, cordate houttuynia, honeysuckle, spirulina, dietary fiber, yeast wherein two or more or all mix.

3. the full nutritional formulas formula of constipation according to claim 1, is characterised in that and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food according to described formula mixing.

4. the full nutritional formulas formula of constipation according to claim 1, is characterized in that described prebiotics is. have that very strong field planting effect prebiotics is Chinese yam to external source probio, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, the extract of jerusalem artichoke, stachyose, yeast and common prebiotics wherein several or all mix.

5. require the full nutritional formulas formula of the constipation described in 1, it is characterized in that described amino acid is Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

6. the full nutritional formulas formula of constipation according to claim 1, is characterized in that described carbohydrate is Arabinose, glucose, fructose, galactolipin, lactose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

7. the full nutritional formulas formula of constipation according to claim 1, is characterized in that with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the anti-effect that treats constipation of product is significantly improved compared with the like product of market.

8. the full nutritional formulas formula of constipation according to claim 1, is characterized in that described vitamin is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix; Described mineral matter is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix.

9. the full nutritional formulas formula of constipation according to claim 1, is characterized in that described small peptide is marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide is wherein a kind of, several or all mix.