CN104996994A - Chronic obstructive pulmonary disease specific full nutritional formula food - Google Patents

Abstract

The present invention belongs to the technical field of medicine food homology formulas and new resource food, and specifically provides a chronic obstructive pulmonary disease specific full nutritional formula food. The formula is based on the requirements of the "General rules for formula food with special medical purposes" and is combined with the physical characteristics of chronic obstructive pulmonary patients, and a variety of medicinal and edible traditional Chinese medicines are reasonably combined according to the quintessence theory of traditional Chinese medicine. The food is prepared from various edible and medicinal Chinese herb extracts extracted with pre-hydrolysis SBE technology, various microencapsulated probiotics, short peptides extracted through biological enzymolysis, prebiotics, amino acids, carbohydrates, healthy functional fats, vitamins and minerals. According to the invention, the obtained formula food can be adopted as the sole nutrition source to meet the nutritional needs of the chronic obstructive pulmonary disease patients, and can further provide effects of spleen strengthening and lung tonifying, heat-clearing and detoxicating, spleen-stomach invigorating and Qi replenishing, phlegm dissipating and cough stopping, lung tonifying and heat clearing, and chronic obstructive pulmonary disease preventing and curing.

Description

The specific full nutritional formulas of COPD

Technical field

The invention belongs to integration of drinking and medicinal herbs class formula and new resource food technical field, specifically the Traditional Chinese Medicine marrow of " Chinese medicine of integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds with small peptide, prebiotics, amino acid, carbohydrate, the specific full nutrient formulation of control COPD that has the grease of health care, B B-complex, composite mineral matter to make for auxiliary material.

Background technology

COPD is a kind of chronic bronchitis and (or) pulmonary emphysema with airflow obstruction feature, the common chronic disease of pulmonary heart disease and respiratory failure can be further development of, react relevant with the abnormal inflammatory of pernicious gas and deleterious particle, chronic bronchitis is often because of caused by many factors comprehensive and long-term action.Onset and flu have substantial connection, how to fall ill in the season that climate change is more violent, respiratory tract repeatedly virus infections and Secondary bacterial infections is the major reason causing chronic bronchitis to become development and disease aggravation, the relation of smoking and chronic bronchitis is also affirmative, smoker is higher than the illness rate of non-smoker 2 ~ 8 times, and smoking period is more of a specified duration, day smoking capacity larger, illness rate is higher, and smoking cessation can make the state of an illness alleviate.In addition, Long Term Contact industrial dust, atmosphere pollution and intolerance factors are also often the reasons causing chronic bronchitis, and Abwehrkraft des Koepers reduces, respiratory system defense function is impaired, is the internal factor of morbidity, during obstructive ventilatory disorder chronic bronchiolitis, narrow due to small airway, block or subside, result in obstructive ventilatory disorder, residual volume(RV) in alveolar is increased, and, the inflammation of peribronchiolar, make alveolar wall destruction, elasticity weakens, more have influence on the exhaust capacity of lung, tip lung tissue is then expanded because residual volume(RV) is on the increase, alveolar pores expand, alveolar septum also ruptures, the alveolar of expansion merges mutually and forms wind-puff blister cavities, in addition, during ramuscule is gas-tight plug, the air sucked can enter (i.e. alveolar effluent ventilation) in the alveolar of inaccessible far-end through the Lambert hole be present between bronchiole and alveolar, and when exhaling, Lambert hole closes, air can not be discharged, also be cause gas-storing capacity in alveolar to increase, the factor that Palv increases.Elastoser increases, activity increases the relevant endogenous protease mainly elastoser that discharges of neutrophil leucocyte and monocyte occurs with pulmonary emphysema, this enzyme can be degraded the elasticin in lung tissue, the collagen in connective tissue matrix and proteoglycan, destroys alveolar wall structure.Chronic bronchitis with Lung infection, especially smoker, the neutrophil leucocyte oozed out in lung tissue and monocyte more, volume elastoser can be discharged.Meanwhile, neutrophil leucocyte and monocyte also can generate a large amount of oxygen radical, and the methionine that can be oxidized alpha1-antitrypsin activated centre makes it inactivation.Alpha1-antitrypsin is the mortifier of elastoser, then enhances the damaging action of elastoser after inactivation." integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science; The traditional Chinese medical science is always emphasized " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet; Allow people dispel slight illness in the process enjoying cuisines, avoid and have an injection, take medicine, even pain of surgery;

For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard traditional Chinese medicine food clear stipulaties: the specific full nutrient formulation of 2.1.1: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 specific full nutrient formulation: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition;

Traditional Chinese medical science traditional medicine is thought: " spleen (i.e. digestive system) is the foundation of acquired constitution ", and stomach health is healthy basis, and 99% of human nutrition needs by intestinal absorption, and intestinal bowel disease is also the source of ten thousand diseases; But along with the age is larger, in enteron aisle, profitable strain (probio) ratio reduces gradually; As Bifidobacterium accounts for 98% infant period, be down to 10% to during the middle age, within 65 years old, only account for 5% later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies display, normal flora human consumption, immunity and disease-resistant etc. in have many irreplaceable effects; The change of gut flora composition and the generation of various diseases, particularly intestines problem develop closely related, and find from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one intervenes control method safely and effectively;

COPD also there will be intestinal microecology imbalance, and COPD can cause lung aerobic bacteria, fungi showed increased, and anaerobic bacteria significantly reduces, enteron aisle aerobic bacteria, fungi, more blank group of Escherichia coli are significantly increased, and anaerobic bacteria, bacteroid and Bifidobacterium significantly reduce, and the antituberculotic application that chronic obstructive pulmonary disease patients undergoing is a large amount of for a long time, normal floras a large amount of in enteron aisle is killed, increase the weight of the colony balance imbalance in enteron aisle, Bifidobacterium, Bacillus acidi lactici is anaerobic bacteria main in enteron aisle, it plays biological containment function in body bifid, resist invasion and the field planting of alien bacteria, chronic obstructive pulmonary disease patients undergoing intestinal flora dysequilibrium, Bifidobacteriums etc. are run off in a large number, body's immunity is caused to decline, lapsing to of COPD disease is relevant with body's immunity, the raising of immunologic function contributes to the absorption of tuberculosis, prompting chronic obstructive pulmonary disease patients undergoing is while antituberculosis drugs treat, probiotics should be supplemented, to recover the balance of intestinal flora, improve the immunologic function of body, promote the absorption of tuberculosis,

Though direct probiotic oral has certain effect, but due to probio cannot field planting in enteron aisle, and stop, occupy-place is little, easily run off, withdraw rear harmful bacteria and easily recur, associated patient needs long-term taking, and treatment cycle is long, often uses afterwards that recurrence rate is very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by the key technology research to probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts " Chinese medicine of the integration of drinking and medicinal herbs " compound seeking to improve probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can play field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity etc. of raising probiotic cell, based on above-mentioned key element, suitable food materials screen from tens of kinds " Chinese medicines of integration of drinking and medicinal herbs " in this seminar, Late Cambrian interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and inulin and stachyose, yeast, after Glu etc., very strong field planting effect is had to external source probio, prescription for probio in enteral microecological formulation is selected to provide experimental basis,

Favourable is in the market primary raw material in order to eat source property small peptide, add the Radix Codonopsis of medicine-food two-purpose, the bighead atractylodes rhizome, the Radix Astragali, the tuber of stemona, the fruit of Chinese magnoliavine, the extract of Cordyceps sinensis etc., B B-complex and mineral matter, composition compound prescription, utilize the product that probio is primary raw material in addition, but also do not find the constitutive character in conjunction with Patients with Chronic Obstructive Pulmonary Disease, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of more than ten kinds medicine-food two-purposes, multiple probio, prebiotics is primary raw material, with small peptide, amino acid, carbohydrate, there is the grease of health care, B B-complex, the full nutrient formulation that composite mineral matter auxiliary material is made, specific full nutrient formulation or similar products.

goal of the invention

The object of the invention is on the theoretical treatment method of succession traditional Chinese medical science marrow, the initiative extract by multiple anti-COPD probio and " Chinese medicine of integration of drinking and medicinal herbs " compound combines, add with small peptide, amino acid, carbohydrate, there is the grease of health care, B B-complex, composite mineral matter is auxiliary material, Patients with Chronic Obstructive Pulmonary Disease institute essential nutrients can not only be supplemented, improve body nutrition condition, can also and utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutrient formulation that the acceptable applicable Patients with Chronic Obstructive Pulmonary Disease of people is edible, specific full nutrient formulation or nonspecific full nutrient formulation.

summary of the invention:

This R&D team is according to the requirement of " special medicine purposes formula food general rule ": 1) fatty energy supply ratio should be 30%-55%; When fatty energy supply is than >40%, the energy that medium chain triglyceride (MCT) provides should be the 10%-20% of gross energy.2) if add n-3 aliphatic acid (in EPA and DHA), the energy supply ratio in formula should be 1%-6%, does corresponding requirements to the energy supply of linoleic acid and alpha-linolenic acid than no longer simultaneously, in conjunction with the constitutive character of Patients with Chronic Obstructive Pulmonary Disease, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears benefit ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt Chinese medical extract elite and the new resource food of one or more medicine-food two-purposes, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, there is the grease of health care, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets Patients with Chronic Obstructive Pulmonary Disease, also has clearing heat and eliminating phlegm, warming lung to reduce watery phlegm, promoting blood circulation and removing blood stasis, to activate yang a surname's numbness, reinforce the spleen to benefit the lung, invigorate the lung and the kidney, supplementing qi and nourishing yin and control COPD specific full nutrient formulation (compound prescription be combined into),

1. the main component of the present invention's formula is:

Chinese medical extract is dirty with being adjusted to main principle from the liver,spleen,kidney three theory of traditional Chinese medical science according to the constitutive character of Patients with Chronic Obstructive Pulmonary Disease, utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function control COPD, and choose following several large class medicine and carry out compatibility; Wherein: invigorate the lung and the kidney: Cordyceps sinensis, lucidum spore powder, Cordyceps militaris, the sterculia seed, Momordica grosvenori, Radix Isatidis, loguat leaf, ginseng, Guangdong Cordyceps militaris, Saussurea involucrata culture, the Radix Astragali, coix seed, the stem of noble dendrobium; Clearing heat and detoxicating:, Chinese mesona herb (celestial grass), selfheal, frangipanis, Radix Glycyrrhizae, honeysuckle radix polygonati officinalis, the membrane of a chicken's gizzard, Bulbus Fritillariae Cirrhosae, the fruit of Chinese magnoliavine; Tonifying middle-Jiao and Qi; Radix Codonopsis, the bighead atractylodes rhizome, almond, lotus seeds, radix platycodi, spina date seed; Preventing phlegm from forming and stopping coughing: Liu Yazi, combined spicebush leaf, French beans, radix platycodi, chrysanthemum, lily, lotus seeds;

Medicinal and edible Chinese medicine extract of the present invention refers to lucidum spore powder, Radix Codonopsis, the bighead atractylodes rhizome, the Radix Astragali, lily, the fruit of Chinese magnoliavine, Cordyceps sinensis, Bulbus Fritillariae Cirrhosae, the stem of noble dendrobium, Cordyceps militaris, the sterculia seed, Momordica grosvenori, Radix Isatidis, loguat leaf, cordate houttuynia, ginseng, Radix Glycyrrhizae, date, honeysuckle, coix seed, radix polygonati officinalis, the membrane of a chicken's gizzard, French beans, chrysanthemum, spina date seed, almond, lotus seeds, radix platycodi, line leaf broom top, Liu Yazi, eucommia Bark male flower, ampelopsis grossdentata leaf, phoenix peony, combined spicebush leaf, leaf of Moringa, Gynura divaricata, Chinese mesona herb (celestial grass), selfheal, frangipanis, Acerola cherry fruit, Opuntia ficus, Leaves of Hippophae L, radix bardanae, cynanchum auriculatum Royle, Guangdong Cordyceps militaris, Saussurea involucrata culture, breast mineral salt one wherein, several or whole, biological enzymolysis or prehydrolysis SBE is adopted to extract and microencapsulation, spray-dried and cryodesiccated extract all mixes,

2. many kinds of probios: make probio major part can arrive enteron aisle by the strong acid environment of stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote the absorption to trace element, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, obviously can reduce the level of intestinal endotoxemia and the generation of preventing liver injury; Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, research application enteron aisle is had not absorb rifamycin antibiotic former times bright (rifaximin), by suppressing the growth of urease-producing and product ammonium bacteria in enteron aisle, prevent and treat the generation of COPD encephalopathic;

Multiple probio of the present invention all adopts the probio after microencapsulation, and the probio described in it is: Bifidobacterium, lactobacillus, streptococcus thermophilus, Pediococcus acidilactici are wherein a kind of, several or all mix;

Bifidobacterium above a refers to: bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, animal bifidobacteria (bifidobacterium lactis);

Lactobacillus above b refers to: lactobacillus acidophilus, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii subspecies, lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus, lactobacillus paraceasi, Lactobacillus crispatus, lactobacillus delbruockii subspecies bulgaricus, lactobacillus reuteri;

3. small peptide: be oligopeptide, refer to the small molecule protein utilizing bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is at below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need directly to absorb through digestion, bioavailability is high, absorbing and utilizing the amino acid and complete protein that are better than dissociating, can be applicable in Protein intake food, especially for the crowd that abilities of digestive and absorption is low, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function improving small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,

Small peptide of the present invention refers to that maize oligopeptide, wheat oligopeptide, marine collagen peptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix;

4. prebiotics: with short probio intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most enteron aisle spoilage organisms, but beneficial bacteria in human body can be promoted---the growth and breeding of lactobacillus, Bifidobacterium, thus spoilage organisms can be suppressed to grow, contribute to improving and maintaining enteron aisle normal function; Long-term edible can to delay senility, defaecation, raising immunity, the absorptivity that alleviates burden of liver, improve nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, knot intestinal pH is reduced, suppresses the growth of intestinal harmful bacillus; Water-Electrolyte in small intestine is made to be trapped in enteric cavity, produce and highly ooze effect, enterocinesia is stimulated to cause laxative, thus promote the discharge of intestinal endotoxin and other toxicants, lactulose also can directly endotoxin in deactivation enteron aisle, reduce gut pH, extensively model is applied to the treatment of COPD encephalopathic;

Prebiotics of the present invention is 2 classes

A. have very strong field planting effect prebiotics to external source probio: Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin extract;

B. common prebiotics: oligoisomaltose, FOS, trehalose, soyabean oligosaccharides, xylo-oligosaccharide, cotton seed compound sugar, stachyose, yeast;

Prebiotics of the present invention is: the extract of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin, cotton seed compound sugar, stachyose, yeast, oligoisomaltose, trehalose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix;

5. carbohydrate: carbohydrate is by carbon, hydrogen and oxygen three kinds of element compositions, it is for human body provides nutrient the most cheap in three of heat energy kinds of main nutrients, when taking in sufficient, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,

Carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, polyfructosan, galactolipin, lactose, glucose, maltose, carbohydrate, has the grease of health care, starch, glycogen one wherein, several or all mix;

6. there is the grease of health care to refer to there is health-care effect to the person, and finished product energy can be increased, make the energy contained by the every 100g of finished product of the present invention should be not less than 295kJ (70kcal); As the street cleaner that fish oil is human vas, can also prevention of arterial sclerosis, apoplexy and heart disease.Fish oil is the diseases such as hypertension, coronary heart disease, headstroke, diabetes, rheumatic arthritis, cancer; Linseed oil has fat-reducing, reduces cholesterol, improves the effects such as renal function; Peony seed oil has reducing blood lipid and hypotensive, strengthens autoimmunity, prevention diabetes, effect of anti-curing cancers; Samara oil prevents and treats hypertension, high fat of blood, effect of the illnesss such as vascular sclerosis;

Of the present invention have the grease of health care to refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix,

7. amino acid: be divided into essential amino acid and nonessential amino acid, is the base unit forming protein, gives protein specific molecular morphosis, make it have biochemical activity; Absorb appropriate methionine and contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances; Leucine can repair muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress cancer growth, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to changing the ammonia in blood into urea and excreting out; For hyperammonemia, hepatic dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses nervous by vegetative nerve and alimentary canal that is that cause festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improving water flood and adjustment mood;

Amino acid of the present invention refers to Glu, GABA, pearl Gly-His-Lys, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix;

8. vitamin and mineral matter: vitamin and mineral matter are the nutrients of needed by human, the nutrient of the vitamin added in the present invention to be vitamin and mineral matter be needed by human;

The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix;

The mineral matter added in the present invention is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;

In the present invention, the addition of vitamin and minerals performs with reference to " special medicine purposes formula food general rule ", and existing for 1000g finished product, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e0.02g, Cobastab u0.03g, potassium citrate 0.03g, natrium citricum 0.04, tricalcium phosphate 0.0003g, magnesium chloride 0.0003g g, potassium chloride 0.0003g, phosphatidase 0 .002g, Choline Chloride 0.002g, magnesium monohydrogen phosphate 0.002g, L-AA 0.1g, sodium chloride 0.02g, ascorbyl palmitate 0.1g, ferric pyrophosphate 0.003g, zinc sulfate 0.0003g, niacinamide 0.0003g, mixed tocopherol concentrate 0.0003g, D-VB5 calcium 0.0003g, ferrous sulfate 0.002g, manganese sulfate 0.002g, dl-α-D-α-tocopherol acetate 0.0003g, puridoxine hydrochloride 0.02g, thiamine hydrochloride 0.02g, riboflavin 0.0003g, palmitic acid 0.0003g, vitamin A 0.0003g, copper sulphate 0.002g, beta carotene 0.002g, potassium molybdate 0.1g, KI 0.1g, chromium chloride 0.1g, sodium selenate 0.1g, Bio 0.1g, phytondione 0.02g, vitamine D3 0.02g, cyanocobalamin 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, fluorine 0.00001g,

The present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat COPD significantly improves compared with the like product of market;

9. adopt above-mentioned integrated innovation technique various batching to be mixed solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add black sesame powder etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out in clean dried environment;

The characteristic of the specific full nutrient formulation of this formula and the following aspects is mainly manifested in the effect of body:

1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with the constitutive character of Patients with Chronic Obstructive Pulmonary Disease, the achievement in research developments such as the advanced physiology of comprehensive nowadays American Harvard University, medicine, nutrition and clinical practice, vary with each individual, gold compatibility;

2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", the Chinese medical extract elite of more than 10 kinds medicine-food two-purposes, multiple probio, prebiotics is adopted to be primary raw material, with prebiotics, carbohydrate, amino acid, the grease having health care, multivitamin and mineral matter for auxiliary material, the organic assembling of various batching, various function is merged, and by the synergy between active ingredient, humidification effect;

3. there is effective absorbency, utilize formula of the present invention, various component adopts the food of suitable ratio collocation preparation, in isotonic state after a certain amount of water-soluble solution, small intestine can be arrived quickly through stomach, absorb quick, complete, Patients with Chronic Obstructive Pulmonary Disease desired nutritional can be supplemented rapidly, not increase the burden of lung;

4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicine, containing several functions active component, not only increase the concentration of function factor, reduce the absorption of various impurity, contribute to alleviating liver kidney burden, have and strengthen the effect of resistance of human body, also have effect of invigorating the spleen benefit lung, clearing heat and detoxicating, tonifying middle-Jiao and Qi, preventing phlegm from forming and stopping coughing, tonifying lung heat-clearing and control COPD;

5. probio contained in the present invention's formula, multiple probio can safeguard enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and raising body are to the absorption of calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve host to the tolerance of radioactive ray, lactobacillus significantly increases intestinal mucosal immune globulin A (SIgA) content, to body intestinal mucosa local immunity, there is regulating action, regulate stomach, intestines Tiny ecosystem, calcium can be improved, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, the absorption of cholesterol can also be reduced,

6. formula food of the present invention with the food source property bioactive short peptide in multiple source for nitrogenous source, because small peptide does not need digestion and Absorbable rod, more be conducive to the utilization of body, can effectively improve Patients with Chronic Obstructive Pulmonary Disease negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, improves the absorbability of intestinal mucosa;

7. this prescription have employed this team by the achievement to probio key technology research of field planting mechanism in enteron aisle over nearly 3 year, improve " Chinese medicine of integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence combining prebiotics can play the key elements such as field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula greatly strengthen the field planting effect to external source probio;

8. prebiotics contained in the present invention's formula, by promoting the growth and breeding of probio in intestines, suppress the growth of spoilage organisms, form one protective barrier at intestinal mucosal surface simultaneously, the damage of enteron aisle spoilage organisms to intestinal mucosa can be resisted, reduce the absorption of intestinal toxic material, intestines peristalsis can also be promoted, accelerate the discharge of residuals in intestines, constipation can be prevented, and by promoting that the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivator such as small peptide and active polysaccharide has synergy;

9. in the present invention's formula, contained carbohydrate is for human body provides three of heat energy kinds of main nutrients, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) that conveys hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce;

10. in the present invention's formula, the contained grease of health care that has not only has health-care effect to the person, and provides the energy needed for normal life for human body, makes the energy contained by the every 100g of finished product of the present invention should be not less than 295kJ (70kcal);

Amino acid contained in 11. the present invention's formulas, it is the base unit forming protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances, muscle can be repaired, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development;

12. formula foods of the present invention containing multivitamin and mineral matter, can supplement rapidly the micronutrient needed for Patients with Chronic Obstructive Pulmonary Disease, small peptide by with the chelating of calcium, iron, zinc etc. after, further increase the absorptivity of mineral matter element;

Not fatty and cholesterol in 13. the present invention's formulas, while supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, avoid the adverse effect of the high protein diet such as meat, egg.

Detailed description of the invention

Below by following case study on implementation, the invention will be further described, and it will contribute to understanding the present invention.

Case study on implementation one

Realizing the specific full nutrient formulation of the object of the invention COPD is constitutive character in conjunction with Patients with Chronic Obstructive Pulmonary Disease, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, multiple probio, small peptide for primary raw material, with the specific full nutrient formulation having the grease of health care, prebiotics, carbohydrate, amino acid, n-3 aliphatic acid and multivitamin, several mineral materials is made for auxiliary material;

Fill a prescription by following raw materials according and consumption thereof, the extract of medicine-food two-purpose and new resource food: lucidum spore powder 14g, Radix Codonopsis 12g, bighead atractylodes rhizome 12g, Radix Astragali 10g, lily 10g, fruit of Chinese magnoliavine 10g, Cordyceps sinensis 9g, Bulbus Fritillariae Cirrhosae 9g, stem of noble dendrobium 8g, Cordyceps militaris 8g, sterculia seed 8g, Momordica grosvenori 8g, Radix Isatidis 7g, loguat leaf 7g, cordate houttuynia 7g, ginseng 7g, Radix Glycyrrhizae 7g, date 7g, honeysuckle 7g, coix seed 7g, radix polygonati officinalis 6g, the membrane of a chicken's gizzard 6g, French beans 6g, chrysanthemum 6g, spina date seed 6g, almond 6g, lotus seeds 5g, radix platycodi 5g, line leaf broom top 5g, Liu Yazi 5g, eucommia Bark male flower 5g, ampelopsis grossdentata leaf 5g, phoenix peony 4g, combined spicebush leaf 4g, leaf of Moringa 4g, Gynura divaricata 4g, Chinese mesona herb (celestial grass) 4g, selfheal 3g, frangipanis 3g, Acerola cherry fruit 3g, Opuntia ficus 3g, Leaves of Hippophae L 3g, radix bardanae 2g, cynanchum auriculatum Royle 2g, the sub-2g of Guangdong Cordyceps militaris, Saussurea involucrata culture 1g, breast mineral salt 1g, multiple probio 300g, there is the grease 200g of health care, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, n-3 aliphatic acid 40g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e0.02g, Cobastab u0.03g, potassium citrate 0.03g, natrium citricum 0.04, tricalcium phosphate 0.0003g, magnesium chloride 0.0003g g, potassium chloride 0.0003g, phosphatidase 0 .002g, Choline Chloride 0.002g, magnesium monohydrogen phosphate 0.002g, L-AA 0.1g, sodium chloride 0.02g, ascorbyl palmitate 0.1g, ferric pyrophosphate 0.003g, zinc sulfate 0.0003g, niacinamide 0.0003g, mixed tocopherol concentrate 0.0003g, D-VB5 calcium 0.0003g, ferrous sulfate 0.002g, manganese sulfate 0.002g, dl-α-D-α-tocopherol acetate 0.0003g, puridoxine hydrochloride 0.02g, thiamine hydrochloride 0.02g, riboflavin 0.0003g, palmitic acid 0.0003g, vitamin A 0.0003g, copper sulphate 0.002g, beta carotene 0.002g, potassium molybdate 0.1g, KI 0.1g, chromium chloride 0.1g, sodium selenate 0.1g, Bio 0.1g, phytondione 0.02g, vitamine D3 0.02g, cyanocobalamin 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, fluorine 0.00001g,

First will to be Radix Codonopsis during making, the bighead atractylodes rhizome, the Radix Astragali, lily, the fruit of Chinese magnoliavine, Cordyceps sinensis, Bulbus Fritillariae Cirrhosae, the stem of noble dendrobium, the sterculia seed, Momordica grosvenori, Radix Isatidis, loguat leaf, cordate houttuynia, ginseng, Radix Glycyrrhizae, date, honeysuckle, coix seed, radix polygonati officinalis, the membrane of a chicken's gizzard, chrysanthemum, spina date seed, almond, radix platycodi, line leaf broom top, Liu Yazi, eucommia Bark male flower, ampelopsis grossdentata leaf, phoenix peony, combined spicebush leaf, leaf of Moringa, Gynura divaricata, Chinese mesona herb (celestial grass), selfheal, frangipanis, Acerola cherry fruit, Opuntia ficus, Leaves of Hippophae L, radix bardanae, add cycloheptaamylose after cynanchum auriculatum Royle, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract Cordyceps sinensis, Cordyceps militaris, lotus seeds, French beans, lucidum spore powder, Guangdong Cordyceps militaris, Saussurea involucrata culture, breast mineral salt, small peptide, prebiotics, amino acid, carbohydrate, there is the grease of health care, carry out pasteurization after multivitamin and mineral matter are pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require,

Manufacture craft of the present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat COPD significantly improves compared with the like product of market.

Case study on implementation two

The specific full nutrient formulation of above-mentioned COPD also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 8g, sterculia seed 8g, Momordica grosvenori 8g, Radix Isatidis 7g, loguat leaf 7g, cordate houttuynia 7g, ginseng 7g, Radix Glycyrrhizae 7g, date 7g, honeysuckle 7g, coix seed 7g, radix polygonati officinalis 6g, the membrane of a chicken's gizzard 6g, French beans 6g, chrysanthemum 6g, spina date seed 6g, almond 6g, lotus seeds 5g, radix platycodi 5g, line leaf broom top 5g, Liu Yazi 5g, eucommia Bark male flower 5g, ampelopsis grossdentata leaf 5g, phoenix peony 4g, combined spicebush leaf 4g, leaf of Moringa 4g, Gynura divaricata 4g, Chinese mesona herb (celestial grass) 4g, selfheal 3g, frangipanis 3g, Acerola cherry fruit 3g, Opuntia ficus 3g, Leaves of Hippophae L 3g, radix bardanae 2g, cynanchum auriculatum Royle 2g, the sub-2g of Guangdong Cordyceps militaris, Saussurea involucrata culture 1g, breast mineral salt 1g, prebiotics 350g, probio 300g, small peptide 150g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, carbohydrate, there is the grease of health care, 50g, vitamin and mineral matter 25g, and meet fatty energy supply ratio and should be 30%-55%, when fatty energy supply is than >40%, the energy that medium chain triglyceride (MCT) provides should be total energy: the 10%-20% of amount.2) if add n-3 aliphatic acid (in EPA and DHA), energy supply ratio in formula should be 1%-6%, do corresponding requirements to the energy supply of linoleic acid and alpha-linolenic acid than no longer, the energy contained by every 100g should be not less than 295kJ (70kcal) simultaneously.

Case study on implementation three

The specific full nutrient formulation of above-mentioned COPD also comprises following component by weight: the Chinese medical extract elite of several medicine-food two-purpose and new resource food 400g, prebiotics 350g, small peptide 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).

Case study on implementation four

The specific full nutrient formulation of above-mentioned COPD also comprises following component by weight: prebiotics 700g, small peptide 500g, carbohydrate 300g, multiple probio 300g, several amino acids 100g, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).

Case study on implementation five

The specific full nutrient formulation of above-mentioned COPD also comprises following component by weight: prebiotics 500g, small peptide 350g, carbohydrate 300g, multiple probio 250g, several amino acids 100g, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).

Case study on implementation six

The specific full nutrient formulation of above-mentioned COPD also comprises following component by weight: small peptide 350g, prebiotics 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).

Claims (10)

1. the specific full nutritional formulas of COPD, it is characterized in that the constitutive character in conjunction with Patients with Chronic Obstructive Pulmonary Disease, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, multiple probio, small peptide for primary raw material, with the specific full nutrient formulation having the grease of health care, prebiotics, carbohydrate, amino acid, n-3 aliphatic acid and multivitamin, several mineral materials is made for auxiliary material;

Fill a prescription by following raw materials according and consumption thereof, the extract of medicine-food two-purpose and new resource food: lucidum spore powder 14g, Radix Codonopsis 12g, bighead atractylodes rhizome 12g, Radix Astragali 10g, lily 10g, fruit of Chinese magnoliavine 10g, Cordyceps sinensis 9g, Bulbus Fritillariae Cirrhosae 9g, stem of noble dendrobium 8g, Cordyceps militaris 8g, sterculia seed 8g, Momordica grosvenori 8g, Radix Isatidis 7g, loguat leaf 7g, cordate houttuynia 7g, ginseng 7g, Radix Glycyrrhizae 7g, date 7g, honeysuckle 7g, coix seed 7g, radix polygonati officinalis 6g, the membrane of a chicken's gizzard 6g, French beans 6g, chrysanthemum 6g, spina date seed 6g, almond 6g, lotus seeds 5g, radix platycodi 5g, line leaf broom top 5g, Liu Yazi 5g, eucommia Bark male flower 5g, ampelopsis grossdentata leaf 5g, phoenix peony 4g, combined spicebush leaf 4g, leaf of Moringa 4g, Gynura divaricata 4g, Chinese mesona herb (celestial grass) 4g, selfheal 3g, frangipanis 3g, Acerola cherry fruit 3g, Opuntia ficus 3g, Leaves of Hippophae L 3g, radix bardanae 2g, cynanchum auriculatum Royle 2g, the sub-2g of Guangdong Cordyceps militaris, Saussurea involucrata culture 1g, breast mineral salt 1g, multiple probio 300g, there is the grease 200g of health care, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, n-3 aliphatic acid 40g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e0.02g, Cobastab u0.03g, potassium citrate 0.03g, natrium citricum 0.04, tricalcium phosphate 0.0003g, magnesium chloride 0.0003g g, potassium chloride 0.0003g, phosphatidase 0 .002g, Choline Chloride 0.002g, magnesium monohydrogen phosphate 0.002g, L-AA 0.1g, sodium chloride 0.02g, ascorbyl palmitate 0.1g, ferric pyrophosphate 0.003g, zinc sulfate 0.0003g, niacinamide 0.0003g, mixed tocopherol concentrate 0.0003g, D-VB5 calcium 0.0003g, ferrous sulfate 0.002g, manganese sulfate 0.002g, dl-α-D-α-tocopherol acetate 0.0003g, puridoxine hydrochloride 0.02g, thiamine hydrochloride 0.02g, riboflavin 0.0003g, palmitic acid 0.0003g, vitamin A 0.0003g, copper sulphate 0.002g, beta carotene 0.002g, potassium molybdate 0.1g, KI 0.1g, chromium chloride 0.1g, sodium selenate 0.1g, Bio 0.1g, phytondione 0.02g, vitamine D3 0.02g, cyanocobalamin 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, fluorine 0.00001g,

First will to be Radix Codonopsis during making, the bighead atractylodes rhizome, the Radix Astragali, lily, the fruit of Chinese magnoliavine, Cordyceps sinensis, Bulbus Fritillariae Cirrhosae, the stem of noble dendrobium, the sterculia seed, Momordica grosvenori, Radix Isatidis, loguat leaf, cordate houttuynia, ginseng, Radix Glycyrrhizae, date, honeysuckle, coix seed, radix polygonati officinalis, the membrane of a chicken's gizzard, chrysanthemum, spina date seed, almond, radix platycodi, line leaf broom top, Liu Yazi, eucommia Bark male flower, ampelopsis grossdentata leaf, phoenix peony, combined spicebush leaf, leaf of Moringa, Gynura divaricata, Chinese mesona herb (celestial grass), selfheal, frangipanis, Acerola cherry fruit, Opuntia ficus, Leaves of Hippophae L, radix bardanae, add cycloheptaamylose after cynanchum auriculatum Royle, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract Cordyceps sinensis, Cordyceps militaris, lotus seeds, French beans, lucidum spore powder, Guangdong Cordyceps militaris, Saussurea involucrata culture, breast mineral salt, small peptide, prebiotics, amino acid, carbohydrate, there is the grease of health care, carry out pasteurization after multivitamin and mineral matter are pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require,

Manufacture craft of the present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat COPD significantly improves compared with the like product of market.

2. the specific full nutritional formulas of COPD according to claim 1, it is characterized in that described medicine-food two-purpose Chinese herbal medicine extract and new resource food are: Radix Codonopsis, the bighead atractylodes rhizome, the Radix Astragali, lily, the fruit of Chinese magnoliavine, Cordyceps sinensis, Bulbus Fritillariae Cirrhosae, the stem of noble dendrobium, the sterculia seed, Momordica grosvenori, Radix Isatidis, loguat leaf, cordate houttuynia, ginseng, Radix Glycyrrhizae, date, honeysuckle, coix seed, radix polygonati officinalis, the membrane of a chicken's gizzard, chrysanthemum, spina date seed, almond, radix platycodi, line leaf broom top, Liu Yazi, eucommia Bark male flower, ampelopsis grossdentata leaf, phoenix peony, combined spicebush leaf, leaf of Moringa, Gynura divaricata, Chinese mesona herb (celestial grass), selfheal, frangipanis, Acerola cherry fruit, Opuntia ficus, Leaves of Hippophae L, radix bardanae, cynanchum auriculatum Royle, Cordyceps sinensis, Cordyceps militaris, lotus seeds, French beans, lucidum spore powder, Guangdong Cordyceps militaris, Saussurea involucrata culture, breast mineral salt one wherein, several or all mix.

3. the specific full nutritional formulas of COPD according to claim 1, is characterised in that and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food according to described formula mixing.

4. the specific full nutritional formulas of COPD according to claim 1, also comprises following component by weight: the Chinese medical extract elite of several medicine-food two-purpose and new resource food 400g, prebiotics 350g, small peptide 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; And meet fatty energy supply ratio and should be 30%-55%; When fatty energy supply is than >40%, the energy that medium chain triglyceride (MCT) provides should be total energy: the 10%-20% of amount.2) if add n-3 aliphatic acid (in EPA and DHA), energy supply ratio in formula should be 1%-6%, do corresponding requirements to the energy supply of linoleic acid and alpha-linolenic acid than no longer, the energy contained by every 100g should be not less than 295kJ (70kcal) simultaneously.

5. the specific full nutritional formulas of COPD according to claim 1, is characterized in that described probio is: Bifidobacterium, lactobacillus, streptococcus thermophilus, Pediococcus acidilactici, wherein a kind of, several or all mix;

Bifidobacterium above refers to: bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, animal bifidobacteria (bifidobacterium lactis);

Lactobacillus above refers to: lactobacillus acidophilus, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus, lactobacillus paraceasi, Lactobacillus crispatus, lactobacillus delbruockii subspecies bulgaricus, lactobacillus reuteri.

6. the specific full nutritional formulas of COPD according to claim 1, it is characterized in that described prebiotics is: the extraction mixture of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, inulin, cotton seed compound sugar, trehalose, stachyose, yeast, oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix.

7. the specific full nutritional formulas of COPD according to claim 1, is characterized in that described amino acid is: Glu, GABA, pearl Gly-His-Lys, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

8. the medical science formula food of COPD according to claim 1, is characterized in that described carbohydrate is that carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, polyfructosan, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

9. the specific full nutritional formulas of COPD according to claim 1, it is characterized in that the described grease of health care that has is: refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix.

10. the specific full nutritional formulas of COPD according to claim 1, is characterized in that described small peptide is: marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.