CN112138068A - Skin-moistening type disinfectant and production method thereof - Google Patents
Skin-moistening type disinfectant and production method thereof Download PDFInfo
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Abstract
The invention relates to a skin-moistening type disinfectant and a production method thereof. The pharmaceutical composition comprises the following components in parts by weight, 20-25% of pharmaceutical grade glycerol; 62-67% of edible alcohol; 2-5% of lanonol; 1-3% of houttuynia cordata purified liquid; 1-3% of a corydalis bungeana purification solution; 1-3% of ephedra purified liquid; 2-4% of pharmaceutical grade 1, 2 propylene glycol; the balance being deionized water. The production method comprises the following steps of (1) weighing the raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product. The product has the skin moistening effect due to the added lanolin alcohol, and the added herba houttuyniae and herba ephedrae purified liquid and the edible alcohol have the synergistic disinfection effect.
Description
Technical Field
The invention belongs to the technical field of daily chemical products, and particularly relates to a skin moistening type disinfectant and a production method thereof.
Background
With the improvement of living standard of people and the increasing emphasis on health, people put forward higher and higher requirements on the cleanliness of the environment, and people know that the health is kept by timely sterilizing to avoid bacterial infection. When people go out or contact with objects, limbs, particularly hands and faces, are easy to contact and be infected with various pathogenic microorganisms such as bacteria, viruses and the like, if the timely disinfection treatment is not carried out, the infection problem can be caused, and the health of people is seriously influenced. Spraying disinfectant on hands, faces and clothes is an important and effective means for killing bacteria and viruses, and is internationally recognized as the most effective, simplest and most economical method for preventing and controlling disease infection and transmission.
Through packing into the packing bottle that has the pump head nozzle with the antiseptic solution and hand-carrying, take at any time when needs, be the current development direction of antiseptic solution, let people can take at any time through packing the miniaturization, agree with people's current demand well. Disinfectant products are prepared in public places such as families, restaurants, stations, hospitals and the like for people to use at any time, and the disinfectant has very important significance for building the whole social health environment.
The prior disinfectant product has the following problems when in use, particularly when in long-term use: some components in the disinfectant are strong in irritation, and easily cause the problems of rough skin, chapping, peeling and the like when the disinfectant is used for a long time, so that although a good disinfection effect is provided for a user, the disinfectant causes damage to the skin, discomfort is caused, the resistance of the skin is reduced, and the skin is more easily attacked by germs. Therefore, there is a need to develop a relatively mild, low irritation disinfectant product. On the other hand, the sterilization and disinfection effects of the existing disinfection solution are completely provided by the chemical components such as alcohol, chlorhexidine, triclosan and the like, and the more sufficient virus killing effect cannot be provided. Meanwhile, some natural plant extracts are proved to have certain virus killing effects, and the combination of the natural plant extracts and the components of the disinfectant liquid to realize a new type of disinfectant liquid product is a development direction.
Disclosure of Invention
The invention provides a skin moistening type disinfectant for solving the technical problems in the prior art, which ensures the sterilization and disinfection effects of the disinfectant, ensures that the disinfectant has a certain skin moistening effect, avoids skin problems caused by long-time use and has a certain skin moistening effect.
The technical scheme adopted by the invention for solving the technical problems in the prior art is as follows: the skin moistening type disinfectant comprises the following components in parts by weight, 20-25% of pharmaceutical grade glycerol; 62-67% of edible alcohol; 2-5% of lanonol; 1-3% of houttuynia cordata purified liquid; 1-3% of a corydalis bungeana purification solution; 1-3% of ephedra purified liquid; 2-4% of pharmaceutical grade 1, 2 propylene glycol; the balance being deionized water.
The invention has the advantages and positive effects that: compared with the existing disinfectant products, the skin moistening type disinfectant has a certain skin moistening function by adding the lanonol component into the product, solves the problems of rough skin, chapping, peeling and the like caused by long-time use of the existing disinfectant, plays a certain role in protecting the skin, ensures the comfort and simultaneously protects the resistance of the skin of a user. The product takes edible alcohol as a basic disinfection component and is matched with the three Chinese herbal medicine components, so that the disinfection solution has a better disinfection function. Meanwhile, the disinfectant has a certain skin care function and can solve the problems of skin inflammation, red swelling, allergy and the like.
Preferably: the pharmaceutical composition comprises the following components in parts by weight, 20-22% of pharmaceutical grade glycerol; 63-66% of edible alcohol; 2-4% of lanonol; 1-2% of houttuynia cordata purified liquid; 1-2% of a corydalis bungeana purification solution; 1-2% of ephedra purified liquid; 3-4% of pharmaceutical grade 1, 2-propylene glycol; the balance being deionized water.
Preferably: the content of glycerol in the pharmaceutical grade glycerol component is more than or equal to 99.85%, and the content of alcohol in the edible alcohol component is more than or equal to 99.5%.
Preferably: the conductivity of the deionized water was <5 mus/cm.
The invention also aims to provide a production method of the skin-moistening type disinfectant.
The technical scheme adopted by the invention for solving the technical problems in the prior art is as follows: a production method of a skin-moistening type disinfectant comprises the following steps of (1) weighing raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product.
Preferably: the preparation method of the houttuynia cordata purified liquid comprises the following steps: crushing the houttuynia cordata raw material, adding deionized water, and performing reflux extraction for 2-4 times at the extraction temperature of 60-80 ℃ for 1.5-2 h; and combining the extracting solutions, and then performing reduced pressure evaporation to obtain a concentrated solution with the density of 1.1-1.5 g/ml.
Preferably: the preparation method of the corydalis bungeana purification liquid comprises the following steps: crushing a corydalis tuber raw material, and performing reflux extraction for 2-4 times by using ethanol with the concentration of 70%, wherein the extraction temperature is 60-80 ℃, and the extraction time is 1.5-2 h; and combining the extracting solutions, and then performing reduced pressure evaporation to obtain a concentrated solution with the density of 1.1-1.5 g/ml.
Preferably: the preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing raw materials of ephedra, and performing reflux extraction for 2-4 times by using ethanol with the concentration of 70%, wherein the extraction temperature is 60-80 ℃, and the extraction time is 1.5-2 h; and combining the extracting solutions, and then performing reduced pressure evaporation to obtain a concentrated solution with the density of 1.1-1.5 g/ml.
Preferably: in the step (5), the mixture is decolorized by an activated carbon decolorizer.
Detailed Description
In order to further understand the contents, features and effects of the present invention, the following embodiments are described in detail.
Pharmaceutical grade glycerol, also known as pharmaceutical grade glycerol, is a colorless, odorless, sweet organic substance with a clear, viscous liquid appearance. Pharmaceutical grade glycerin or pharmaceutical grade glycerin can absorb moisture from the air, and can also absorb gases such as hydrogen sulfide, hydrogen cyanide, sulfur dioxide and the like. Insoluble in benzene, chloroform, carbon tetrachloride, carbon disulfide, petroleum ether and oils. Glycerol is a backbone component of the triglyceride molecule. Relative density 1.26362, melting point 17.8 ℃ and boiling point 290.0 ℃. The pharmaceutical grade glycerol or pharmaceutical grade glycerol is used for analysis of aqueous solution, solvent, gas meter, hydraulic press shock absorption liquid, softener, nutrient for antibiotic fermentation, drying agent, lubricant, pharmaceutical industry, cosmetic preparation, organic synthesis and plasticizer. Can be dissolved in water in any proportion, and the low-concentration glycerol solution can be used as lubricating oil for moistening skin.
Pharmaceutical grade 1, 2 propylene glycol is an organic compound that is miscible with water, ethanol, and various organic solvents. It is colorless viscous liquid in normal state, almost tasteless, and slightly sweet. Propylene glycol can be used as raw material of unsaturated polyester resin, and can be used as humectant in cosmetics, toothpaste and soap in combination with glycerol or sorbitol. It is used in hair dye as a conditioning agent, a hair conditioner, an antifreeze, a cellophane, a plasticizer and a pharmaceutical industry.
The lanonol is a mixture of steroid alcohol and triterpene alcohol, and contains not less than 30% of cholesterol and 10-13% of isocholesterol. USP-NF20 allowed the inclusion of suitable antioxidants up to 0.1% (w/w), while PhEur2002 allowed the inclusion of the antioxidant lanolin alcohol in the range of up to 200 ppm. Lanonol is used in external preparations and cosmetics, is a hydrophobic matrix with skin-softening and lubricating effects, and can be used in preparations for dry skin and dry eye. Also used as a water-in-oil cream and ointment base, at concentrations as low as 2%.
The herba Houttuyniae purified solution is obtained from herba Houttuyniae Chinese medicinal material. Houttuynia cordata, also known as houttuynia cordata root, is a herb recorded in Chinese pharmacopoeia, and the herb is the dried aerial part of houttuynia cordata of Saururaceae. Harvesting in summer when stem and leaf are flourishing and flower ear is more, removing impurities, and drying in the sun. Yu xing Cao is pungent in flavor and cold in nature and enters lung meridian. Has effects in clearing away heat and toxic materials, relieving swelling, treating sore, promoting urination, removing dampness, clearing away heat, relieving dysentery, invigorating stomach, and promoting digestion, and can be used for treating lung abscess, pyocutaneous disease, hematochezia, and heat accumulation in spleen and stomach due to excess heat, heat toxin, dampness, and disease heat.
The herba corydalis Bungeanae purification solution is obtained from herba corydalis Bungeanae traditional Chinese medicinal materials. Corydalis Bungeana also known as corydalis edulis, corydalis penbergii, corydalis buchneri and the like. Is a perennial herb of Papaveraceae, and has a height of 10-30 cm. Thin and straight root, less branching, light yellowish brown. The stem is thin and weak, and is branched from the base to the periphery, with arrises, grayish green, smooth hair or loose hair. The basal leaves are clustered, and the basal leaves are intergrown and have stalks. The herba corydalis bungeanae has strong adaptability and is fond of warm and cool climate. Cold-resistant and afraid of drought. The soil is not strict, and clay, loam and sandy loam can be planted. The dry whole herbs are used for medicine, have the efficacy of clearing heat and removing toxicity, and are mainly used for treating carbuncle swelling, furuncle, wind-heat type common cold, bronchitis, hepatitis, enteritis and other symptoms.
The herba Ephedrae purification solution is obtained from herba Ephedrae. The herba ephedrae is a plant of ephedrae family, is a wind-cold-dispersing medicine in traditional Chinese medicines and is 20-40 cm high; the wood stem is short or creeping. Three ephedra plants are included: the ephedra herb, the equisetum hiemalis and the Chinese ephedra are herbaceous shrubs, and the adopted parts are herbaceous stems and are also important medicinal plants. The alkaloid is rich in alkaloid, and is the main resource for extracting ephedrine.
Deionized water refers to pure water from which impurities in the form of ions have been removed. The "deionization" as specified by the International organization for standardization ISO/TC 147 is defined as: deionized water completely or incompletely removes ionic species. Mainly adopts a RO reverse osmosis process method to remove anions and cations in water by using ion exchange resin.
Example one
The paint comprises the following components in parts by weight: pharmaceutical grade glycerol 20%; 63% of edible alcohol; 4% of lanonol; 1% of houttuynia cordata purified liquid; 1% of corydalis bungeana purification solution; 1% of ephedra purified liquid; pharmaceutical grade 1, 2 propylene glycol 4%; the balance of 6% is deionized water.
Wherein the pharmaceutical grade glycerol component contains 99.85% of glycerol, the edible alcohol component contains 99.5% of alcohol, and the deionized water has a conductivity of 4 μ S/cm.
The production method comprises the following steps:
(1) weighing the raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product.
Wherein the content of the first and second substances,
the preparation method of the houttuynia cordata purified liquid comprises the following steps: pulverizing herba Houttuyniae, adding deionized water, reflux extracting for 2 times at 60 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.1 g/ml.
The preparation method of the corydalis bungeana purification liquid comprises the following steps: pulverizing herba Violae, and extracting with 70% ethanol under reflux for 2 times at 60 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.1 g/ml.
The preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing herba Ephedrae, extracting with 70% ethanol under reflux for 2 times at 60 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.1 g/ml.
Decoloring by using an activated carbon decoloring device to form a light-colored or colorless final product, and then filling and packaging.
Example two
The paint comprises the following components in parts by weight: pharmaceutical grade glycerol 20%; 64% of edible alcohol; 3% of lanonol; 1.2 percent of houttuynia cordata purified liquid; 1.2 percent of corydalis bungeana purification solution; 1.2 percent of ephedra purified liquid; 3.5% of pharmaceutical grade 1, 2 propylene glycol; the balance 5.9% is deionized water.
Wherein the pharmaceutical grade glycerol component contains 99.85% of glycerol, the edible alcohol component contains 99.5% of alcohol, and the deionized water has a conductivity of 4 μ S/cm.
The production method comprises the following steps:
(1) weighing the raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product.
Wherein the content of the first and second substances,
the preparation method of the houttuynia cordata purified liquid comprises the following steps: pulverizing herba Houttuyniae, adding deionized water, reflux extracting for 3 times at 65 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.2 g/ml.
The preparation method of the corydalis bungeana purification liquid comprises the following steps: pulverizing herba Violae, extracting with 70% ethanol under reflux for 3 times at 65 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.2 g/ml.
The preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing herba Ephedrae, extracting with 70% ethanol under reflux for 3 times at 65 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.2 g/ml.
Decoloring by using an activated carbon decoloring device to form a light-colored or colorless final product, and then filling and packaging.
EXAMPLE III
The paint comprises the following components in parts by weight: 21% of pharmaceutical grade glycerol; 65% of edible alcohol; 3% of lanonol; 1.1% of houttuynia cordata purified liquid; 1.1 percent of corydalis bungeana purification solution; 1.1% of ephedra purified liquid; pharmaceutical grade 1, 2 propylene glycol 3%; the balance 4.7% was deionized water.
Wherein the pharmaceutical grade glycerol component contains 99.9% glycerol, the edible alcohol component contains 99.7% alcohol, and the deionized water has conductivity of 3 μ S/cm.
The production method comprises the following steps:
(1) weighing the raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product.
Wherein the content of the first and second substances,
the preparation method of the houttuynia cordata purified liquid comprises the following steps: pulverizing herba Houttuyniae, adding deionized water, reflux extracting for 3 times at 70 deg.C for 2 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.3 g/ml.
The preparation method of the corydalis bungeana purification liquid comprises the following steps: pulverizing herba Violae, extracting with 70% ethanol under reflux for 3 times at 70 deg.C for 2 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.3 g/ml.
The preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing herba Ephedrae, extracting with 70% ethanol under reflux for 3 times at 70 deg.C for 2 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.3 g/ml.
Decoloring by using an activated carbon decoloring device to form a light-colored or colorless final product, and then filling and packaging.
Example four
The paint comprises the following components in parts by weight: pharmaceutical grade glycerol 22%; 63% of edible alcohol; 2% of lanonol; 2% of houttuynia cordata purified liquid; 2% of corydalis bungeana purification solution; 2% of ephedra purified liquid; 3.5% of pharmaceutical grade 1, 2 propylene glycol; the balance 3.5% is deionized water.
Wherein the pharmaceutical grade glycerol component contains 99.85% of glycerol, the edible alcohol component contains 99.7% of alcohol, and the deionized water has a conductivity of 4 μ S/cm.
The production method comprises the following steps:
(1) weighing the raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product.
Wherein the content of the first and second substances,
the preparation method of the houttuynia cordata purified liquid comprises the following steps: pulverizing herba Houttuyniae, adding deionized water, reflux extracting for 3 times at 75 deg.C for 1.8 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.4 g/ml.
The preparation method of the corydalis bungeana purification liquid comprises the following steps: pulverizing herba Violae, extracting with 70% ethanol under reflux for 3 times at 75 deg.C for 1.8 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.4 g/ml.
The preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing herba Ephedrae, extracting with 70% ethanol under reflux for 3 times at 75 deg.C for 1.8 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.4 g/ml.
Decoloring by using an activated carbon decoloring device to form a light-colored or colorless final product, and then filling and packaging.
EXAMPLE five
The paint comprises the following components in parts by weight: pharmaceutical grade glycerol 20%; 65% of edible alcohol; 2% of lanonol; 1.8 percent of houttuynia cordata purified liquid; 1.8 percent of corydalis bungeana purification solution; 1.8 percent of ephedra purified liquid; pharmaceutical grade 1, 2 propylene glycol 3%; the balance 4.6% is deionized water.
Wherein the pharmaceutical grade glycerol component contains 99.85% of glycerol, the edible alcohol component contains 99.5% of alcohol, and the deionized water has a conductivity of 4 μ S/cm.
The production method comprises the following steps:
(1) weighing the raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product.
Wherein the content of the first and second substances,
the preparation method of the houttuynia cordata purified liquid comprises the following steps: pulverizing herba Houttuyniae, adding deionized water, reflux extracting for 4 times at 75 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.5 g/ml.
The preparation method of the corydalis bungeana purification liquid comprises the following steps: pulverizing herba Violae, and extracting with 70% ethanol under reflux for 4 times at 75 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.5 g/ml.
The preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing herba Ephedrae, extracting with 70% ethanol under reflux for 4 times at 75 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.5 g/ml.
Decoloring by using an activated carbon decoloring device to form a light-colored or colorless final product, and then filling and packaging.
EXAMPLE six
The paint comprises the following components in parts by weight: pharmaceutical grade glycerol 22%; 66% of edible alcohol; 4% of lanonol; 1% of houttuynia cordata purified liquid; 1% of corydalis bungeana purification solution; 1% of ephedra purified liquid; pharmaceutical grade 1, 2 propylene glycol 3%; the balance 2% is deionized water.
Wherein the pharmaceutical grade glycerol component contains 99.85% of glycerol, the edible alcohol component contains 99.5% of alcohol, and the deionized water has a conductivity of 4 μ S/cm.
The production method comprises the following steps:
(1) weighing the raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product.
Wherein the content of the first and second substances,
the preparation method of the houttuynia cordata purified liquid comprises the following steps: pulverizing herba Houttuyniae, adding deionized water, reflux extracting for 2 times at 60 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.1 g/ml.
The preparation method of the corydalis bungeana purification liquid comprises the following steps: pulverizing herba Violae, and extracting with 70% ethanol under reflux for 2 times at 60 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.1 g/ml.
The preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing herba Ephedrae, extracting with 70% ethanol under reflux for 2 times at 60 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.1 g/ml.
Decoloring by using an activated carbon decoloring device to form a light-colored or colorless final product, and then filling and packaging.
EXAMPLE seven
The paint comprises the following components in parts by weight: pharmaceutical grade glycerol 20%; 63% of edible alcohol; 2% of lanonol; 1% of houttuynia cordata purified liquid; 1% of corydalis bungeana purification solution; 1% of ephedra purified liquid; pharmaceutical grade 1, 2 propylene glycol 3%; the balance 9% is deionized water.
Wherein the pharmaceutical grade glycerol component contains 99.85% of glycerol, the edible alcohol component contains 99.5% of alcohol, and the deionized water has a conductivity of 4 μ S/cm.
The production method comprises the following steps:
(1) weighing the raw materials according to the weight ratio; (2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃; (3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C; (4) injecting edible alcohol into the mixing tank and stirring uniformly; (5) and decoloring the mixture to obtain a final product.
Wherein the content of the first and second substances,
the preparation method of the houttuynia cordata purified liquid comprises the following steps: pulverizing herba Houttuyniae, adding deionized water, reflux extracting for 2 times at 80 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.3 g/ml.
The preparation method of the corydalis bungeana purification liquid comprises the following steps: pulverizing herba Violae, and extracting with 70% ethanol under reflux for 2 times at 80 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.3 g/ml.
The preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing herba Ephedrae, extracting with 70% ethanol under reflux for 2 times at 80 deg.C for 1.5 hr; the extracts were combined and evaporated under reduced pressure to give a concentrate with a density of 1.3 g/ml.
Decoloring by using an activated carbon decoloring device to form a light-colored or colorless final product, and then filling and packaging.
The skin-moistening disinfectant product is a low-viscosity product, has good fluidity at normal temperature, is suitable for being filled into a packaging bottle with a nozzle, and is directly sprayed and uniformly smeared on skin to be disinfected when in use. The main components in the product are quickly volatilized into the air, so that the disinfectant is a no-clean type disinfectant product.
Claims (9)
1. A skin moistening type disinfectant is characterized in that: comprises the following components in parts by weight,
2. the skin moisturizing disinfectant as claimed in claim 1, wherein: comprises the following components in parts by weight,
3. the skin moisturizing disinfectant as claimed in claim 2, wherein: the content of glycerol in the pharmaceutical grade glycerol component is more than or equal to 99.85%, and the content of alcohol in the edible alcohol component is more than or equal to 99.5%.
4. The skin moisturizing disinfectant as claimed in claim 3, wherein: the conductivity of the deionized water was <5 mus/cm.
5. The method for producing a skin-moisturizing disinfectant as claimed in claim 4, wherein: comprises the following steps of (a) carrying out,
(1) weighing the raw materials according to the weight ratio;
(2) injecting pharmaceutical grade glycerol, pharmaceutical grade 1, 2 propylene glycol, lanolin alcohol and deionized water into a mixing tank, stirring uniformly and heating to 80 ℃;
(3) injecting the herba Houttuyniae purified solution, herba Violae purified solution and herba Ephedrae purified solution into a mixing tank, stirring, and cooling to 40 deg.C;
(4) injecting edible alcohol into the mixing tank and stirring uniformly;
(5) and decoloring the mixture to obtain a final product.
6. The method of claim 5, wherein: the preparation method of the houttuynia cordata purified liquid comprises the following steps: crushing the houttuynia cordata raw material, adding deionized water, and performing reflux extraction for 2-4 times at the extraction temperature of 60-80 ℃ for 1.5-2 h; and combining the extracting solutions, and then performing reduced pressure evaporation to obtain a concentrated solution with the density of 1.1-1.5 g/ml.
7. The method of claim 5, wherein: the preparation method of the corydalis bungeana purification liquid comprises the following steps: crushing a corydalis tuber raw material, and performing reflux extraction for 2-4 times by using ethanol with the concentration of 70%, wherein the extraction temperature is 60-80 ℃, and the extraction time is 1.5-2 h; and combining the extracting solutions, and then performing reduced pressure evaporation to obtain a concentrated solution with the density of 1.1-1.5 g/ml.
8. The method of claim 5, wherein: the preparation method of the herba ephedrae purification liquid comprises the following steps: pulverizing raw materials of ephedra, and performing reflux extraction for 2-4 times by using ethanol with the concentration of 70%, wherein the extraction temperature is 60-80 ℃, and the extraction time is 1.5-2 h; and combining the extracting solutions, and then performing reduced pressure evaporation to obtain a concentrated solution with the density of 1.1-1.5 g/ml.
9. The method of claim 5, wherein: in the step (5), the mixture is decolorized by an activated carbon decolorizer.
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