CN112121119B

CN112121119B - Ointment for treating hydrofluoric acid burn

Info

Publication number: CN112121119B
Application number: CN202011113453.7A
Authority: CN
Inventors: 张学连; 张文生; 张大祯; 赵威龙; 张涵昱
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-10-17
Filing date: 2020-10-17
Publication date: 2022-04-15
Anticipated expiration: 2040-10-17
Also published as: CN112121119A

Abstract

The invention relates to an ointment for treating hydrofluoric acid burn, which can improve the cure rate, shorten the treatment time, reduce scars and even remove the scars, and is prepared from the following components in parts by weight: the preparation method comprises the following steps of taking apocynum venetum, castor bean, leech, star anise, white scallop, tripterygium wilfordii, oldenlandia diffusa, sophora flower rice, angelica dahurica, angelica sinensis, dragon's blood, white wax, calomel, liquorice, lithospermum and vaseline as raw material medicines, putting the sophora flower rice into water to prepare a sophora flower rice aqueous extract stock solution, grinding the apocynum venetum, the castor bean, leech, star anise, white scallop, the tripterygium wilfordii and the oldenlandia into powder, uniformly mixing the sophora flower rice aqueous extract stock solution, blending to obtain a mixture A, and grinding the angelica dahurica, the angelica sinensis, the dragon's blood, the white wax, the calomel, the liquorice and the lithospermum into powder, uniformly mixing the mixture A with the vaseline to obtain a mixture B, and uniformly mixing the mixture A. The invention has low cost, greatly shortens the treatment period, causes little pain to patients during treatment, is easy to accept, has obvious curative effect and high cure rate, and can even cure part of patients to have no scars.

Description

Ointment for treating hydrofluoric acid burn

Technical Field

The invention relates to the field of traditional Chinese medicines, in particular to an ointment for treating hydrofluoric acid burn.

Background

Hydrofluoric acid is a colorless, transparent liquid, although not a strong acid, but because of its strong osmotic and corrosive forces, when it comes into contact with the skin, the clinical manifestation of hydrofluoric acid burns is that the degree of skin damage is related to the concentration of hydrofluoric acid, the contact time, and the contact site, and the higher the concentration, the longer the contact time, the softer or denser the affected tissue, and the more rapid and intense the action. Pain and skin damage often occur immediately upon exposure to hydrofluoric acid at concentrations above 30%. Pain and skin burns often begin to occur over several hours when exposed to low concentrations. The local skin lesion is initially red spot, then turns into white edema with red halo, then turns into light green gray necrosis, and then turns into dark brown or black thick scab, and the scab is removed to form ulcer. Lesions in the finger area often turn into bullous lesions, and the nail plate is often affected simultaneously, with red and swollen nail bed and nail periphery. When serious, the nail bed is separated from the nail plate; high concentration burns often show progressive necrosis with slow healing of ulcers. Severe patients are affected with local bones and are easy to cause skin necrosis to form ulcer, most of the existing common means for treating hydrofluoric acid burn are western medicines, severe patients need to be treated by combining with an operation, and the treatment method has the disadvantages of high treatment cost, long treatment time, low cure rate and severe scars after treatment.

Disclosure of Invention

The invention provides the ointment for treating hydrofluoric acid burn, which aims to solve the problems of high cost, long treatment time, low cure rate and serious scars after treatment of the existing hydrofluoric acid burn, and can improve the cure rate, shorten the treatment time, reduce the scars and even remove the scars.

The technical scheme of the invention is that the material is prepared from the following components by weight: 15-20g of apocynum venetum, 25-30g of castor bean, 3-5g of leech, 25-30g of star anise, 12-18g of white scallop, 7-9g of tripterygium wilfordii, 12-18g of spreading hedyotis herb, 27-33g of sophora flower rice, 27-33g of angelica dahurica, 90-110g of angelica, 27-33g of dragon's blood, 17-23g of white wax, 17-23g of calomel, 45-55g of liquorice, 45-55g of lithospermum and 550g of vaseline as raw materials, firstly, putting the sophora flower rice into water, wherein the weight ratio of the sophora flower rice to the water is 1: 20, boiling with strong fire, keeping the mixture on slow fire for 30-1 hour, filtering, collecting filtrate, adding water which is 10 times of the sophora flower rice into sophora flower rice dregs, boiling with strong fire, keeping the mixture on slow fire for 30-45 minutes, collecting the filtrate, combining the two filtrates to obtain a mixed solution, adding 0.1 times of lead acetate into the mixed solution, standing for 20-24 hours, centrifuging for 2 times, 5-8 min each time, taking the supernatant to obtain a sophora flower rice water extract stock solution, respectively grinding apocynum venetum, castor bean, leech, anise, fritillary, tripterygium wilfordii and herba hedyotis into fine powder, uniformly mixing, adding the sophora flower rice water extract stock solution, uniformly mixing to obtain a mixture A, respectively grinding the mixture A, the angelica dahurica, the angelica, the dragon's blood, the white wax, the calomel, the liquorice and the lithospermum into fine powder, uniformly mixing, adding vaseline into the mixture B, uniformly mixing to obtain a mixture B, adding the mixture A into the mixture B, and uniformly mixing to obtain the sophora flower rice wine.

The invention has low cost, greatly shortens the treatment period, causes little pain to patients during treatment, is easy to accept, has obvious curative effect and high cure rate, and can even cure part of patients to have no scars.

Detailed Description

The invention is further illustrated by the following examples:

example 1

The invention is prepared from the following components by weight: the preparation method comprises the following steps of firstly putting sophora flower rice into 600ml of water, decocting the sophora flower rice with strong fire until the sophora flower rice is boiled, keeping the sophora flower rice with slow fire for 45 minutes, filtering, collecting filtrate, adding 300ml of water into sophora flower rice dregs, decocting the sophora flower rice with strong fire until the sophora flower rice is boiled, keeping the sophora flower rice with slow fire for 40 minutes, collecting filtrate, combining the two filtrates to obtain a mixed solution, adding 0.1 time of lead acetate into the mixed solution, standing for 22 hours, centrifuging for 2 times, 6min for each time, and 1500 r/min, taking supernatant to obtain a sophora flower rice water extract stock solution, and preparing the sophora flower rice water extract stock solution, the apocynum venetum, the castor bean, leech, the anise, the white scallop, the tripterygium wilfordii, the celastrum wilfordii, 15g of white scallop, 8g of tripterygium wilfordii, 15g of white pepper, 8g of tripterygium wilfordii, 15g of tripterygium wilfordii, 30g of sophora flower rice, 30g of angelica dahurica flower rice, 30g of radix angelicae, 20g of slow fire, 20g of mercurous alba, 20g of mercurous chinensis and 500g of mercurous chinensis are taken as raw materials, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

Example 2

The invention is prepared from the following components by weight: the preparation method comprises the following steps of firstly putting sophora flower rice into 660ml of water, decocting the sophora flower rice to boiling with strong fire, keeping the mixture for 30 minutes, filtering, collecting filtrate, adding 330ml of water into sophora flower rice dregs, decocting the sophora flower rice to boiling with slow fire, keeping the mixture for 30 minutes, collecting filtrate, combining the filtrates to obtain a mixed solution, adding 0.1 time of lead acetate into the mixed solution, standing for 20 hours, centrifuging for 2 times, 7 minutes each time, and 1500 r/min, taking supernatant to obtain sophora flower rice water extract stock solution, and preparing the sophora flower rice water extract stock solution, namely the apocynum venetum, the castor bean, the leech, the anise, the fritillary bulb, the tripterygium wilfordii, 25g of star anise, 12g of white scallop, 12g of white pepper, 12g of white beetroot, 9g of tripterygium wilfordii, 55g of liquorice and 450 parts of vaseline as raw materials, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

Example 3

The invention is prepared from the following components by weight: 20g of apocynum venetum, 25g of castor bean, 3g of leech, 30g of star anise, 18g of white scallop, 7g of tripterygium wilfordii, 18g of oldenlandia diffusa, 27g of sophora flower rice, 33g of angelica dahurica, 110g of angelica, 33g of dragon's blood, 17g of white wax, 23g of calomel, 45g of liquorice, 45g of lithospermum and 550g of vaseline are taken as raw materials to prepare the Chinese medicinal preparation, firstly, the sophora flower rice is taken and put into 540ml of water, decocted with strong fire until boiling, switched to slow fire, kept for 1 hour, filtered, filtrate is collected, 270ml of water is added into sophora flower rice dregs, decocted with strong fire until boiling, switched to slow fire, kept for 45 minutes, filtrate is collected, two filtrates are combined to obtain a mixed solution, lead acetate which is 0.1 time of the mixed solution is added, the mixed solution is kept still for 24 hours, centrifuged for 2 times, each time, at the speed of 8min and 1500 r/min, the supernatant is taken to obtain a raw solution of the Chinese scholartree flower rice aqueous extract, the raw solution, the apocynum venetum, the castor bean, the leech, the Chinese anise, the white scallop, the tripterygium wilfordii, the white scallop, the white pepper, the sophora flower rice, the other, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

Example 4

The invention is prepared from the following components by weight: the preparation method comprises the following steps of firstly putting sophora flower rice into 540ml of water, decocting the sophora flower rice with strong fire until the sophora flower rice is boiled, keeping the sophora flower rice with slow fire for 30 minutes, filtering, collecting filtrate, adding 270ml of water into sophora flower rice dregs, decocting the sophora flower rice with strong fire until the sophora flower rice is boiled, keeping the sophora flower rice with slow fire for 30 minutes, collecting filtrate, combining the two filtrates to obtain a mixed solution, adding 0.1 time of lead acetate into the mixed solution, standing for 20 hours, centrifuging for 2 times, 5 minutes each time for 5 minutes, and 1500 r/min, taking supernatant to obtain a sophora flower rice water extract stock solution, and preparing the apocynum venetum, the castor bean, leech, the anise, the white scallop, the tripterygium wilfordii, the sophora japonica thunbergii, the apocynum venetum, 12g of white scallop, 7g of tripterygium wilfordii, 12g of white flower, 7g of tripterygium wilfordii, 12g of herba polygoni, 12g of celastri, and 450g of vaseline as raw materials, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

Example 5

The invention is prepared from the following components by weight: 20g of apocynum venetum, 30g of castor bean, 5g of leech, 30g of star anise, 18g of white scallop, 9g of tripterygium wilfordii, 18g of oldenlandia diffusa, 33g of sophora flower rice, 33g of angelica dahurica, 110g of angelica, 33g of dragon's blood, 23g of white wax, 23g of calomel, 55g of liquorice, 55g of lithospermum and 550g of vaseline are taken as raw materials to prepare the Chinese medicinal preparation, firstly, the sophora flower rice is taken and put into 660ml of water, decocted with strong fire until boiling, switched to slow fire, kept for 1 hour, filtered, filtrate is collected, 330ml of water is added into sophora flower rice dregs, decocted with strong fire until boiling, switched to slow fire, kept for 45 minutes, filtrate is collected, two filtrates are combined to obtain a mixed solution, lead acetate which is 0.1 time of the mixed solution is added, the mixed solution is kept still for 24 hours, centrifuged for 2 times, each time, 1500 r/min, the supernatant is obtained, and the mixed solution is obtained to obtain a raw solution, and the raw solution of the sophora flower rice water extract, the apocynum venetum, the castor bean, the leech, the Chinese anise, the white scallop, the tripterygium wilfordii, the sophora flower rice, the black bean, the black sesame, the black bean, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

The above medicament, wherein:

and (3) bluish dogbane: cleaning, cutting into segments, and sun drying, and has effects of clearing heat, calming liver, inducing diuresis and relieving swelling;

castor bean: removing impurities, sun drying, removing shell, mashing, and has effects of relieving swelling, removing toxic substance, and removing stagnation;

leech: cleaning, cutting into segments, drying, and has effects of removing blood stasis, and dredging channels;

anise fragrant: remove silt and dry in the sun, it can be used for treating sore, furuncle, pyogenic infections and tinea capitis;

white shell: removing meat, cleaning, sun drying, and clearing away heat; promoting urination, improving eyesight and removing nebula;

thunder god vine: removing impurities, cleaning root and leaf, slightly stewing, slicing, shredding, drying, promoting blood circulation and removing obstruction in collaterals; relieving swelling and pain; the efficacy of killing insects and removing toxicity;

and (3) white flower grass: removing impurities, cleaning, sun drying, clearing heat and promoting diuresis, and can be used for treating heat stranguria;

and (3) sophora flower rice: removing impurities and dust, cooling blood, stopping bleeding, and clearing liver-fire;

radix angelicae: removing impurities, cleaning with water, soaking, taking out, moistening, slightly cooling until the outer skin is not greasy, moistening, slicing, and drying to obtain the final product with effects of dispelling pathogenic wind, eliminating dampness, relieving swelling and pain;

chinese angelica: removing impurities, cleaning, moistening, slicing, and sun drying, and has effects of replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation;

dragon's blood: removing impurities, pulverizing into granules, and has effects of removing blood stasis, relieving pain, stopping bleeding, and promoting granulation;

white wax: removing impurities, and mashing to obtain hemostatic, granulation promoting, and wound healing effects;

calomel: killing insects; counteracting toxic substances; removing the rotten part; relieving itching; eliminating phlegm; removing water; the efficacy of relaxing the bowels;

licorice root: removing impurities, cleaning, moistening, slicing, drying, and has effects of invigorating spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the medicines;

lithospermum: removing residual stem and soil, sun drying or oven drying with slow fire, and has effects of cooling blood, promoting blood circulation, clearing heat, and removing toxic substance;

vaseline: is medical vaseline and has the effects of moistening and moisturizing.

The medicine has the effects of diminishing inflammation, relieving pain, removing necrotic tissue, promoting granulation, clearing away heat and toxic materials, inducing diuresis and reducing edema, can be effectively used for treating hydrofluoric acid burn, has a definite curative effect, and obtains a good curative effect through clinical application, and the related test data are as follows:

1 data and method

1.1 criteria for selecting cases

1 data and method

1.1 criteria for selecting cases: 97 patients with hydrofluoric acid burn meeting the selection standard are selected, wherein 31 patients with hydrofluoric acid burn heads, 56 patients with hydrofluoric acid burn fingers and 10 patients with hydrofluoric acid burn at a plurality of positions on bodies, among the 97 patients with hydrofluoric acid burn, 61 patients with deep III degree burn and deep III degree burn areas smaller than 10%, 36 patients with deep II degree burn, and the patients are 20-60 years old.

1.2 diagnostic criteria:

1.2.1 there was a history of hydrofluoric acid exposure.

1.2.2 local wound surface: the early stage of the medicine is asymptomatic, and severe pain appears after 1-8 h. The skin turns dark red and dry gradually at the initial stage, then the wound surface becomes pale and necrotic, and finally becomes purplish black or black, and the skin becomes ulcer after decrustation; also for some patients with local blister, the blister is brown and the wound is not easy to heal.

1.2.3. Patients with different degrees of burn have symptoms of fluorosis, such as headache, hypodynamia, nausea, vomiting, convulsion, coma, circulatory failure, kidney damage and the like.

1.3 treatment protocol: firstly removing necrotic tissues, then alternately flushing with hexafluoro-Ling and calcium gluconate for 15 minutes, injecting a 2.5 mass percent calcium gluconate injection to the burn, then using the ointment once a day, wherein the application area of each time is larger than the burn area, and simultaneously carrying out corresponding infusion treatment on patients with convulsion, coma, circulatory failure and kidney damage, 7 days are a treatment course, and the treatment effect is counted in 3 treatment courses.

2 evaluation of therapeutic Effect

And (3) curing: the wound surface is completely healed, no scar is seen, and the normal living ability of the patient is recovered.

The effect is shown: necrotic tissue dissolves, the wound surface heals, scars appear, and normal life is not affected.

The method has the following advantages: pain disappeared, black tissue reddened, and the wound gradually becomes scab and heals.

And (4) invalidation: failing to meet the above criteria or suffering from deterioration to a different extent.

3, statistical analysis: 31 patients with hydrofluoric acid burn heads cure 20 cases, have 5 cases of obvious effect, 4 cases of effect and 2 cases of no effect, and the total effective rate is 94%; 56 patients with finger burn caused by hydrofluoric acid cure 40 cases, have obvious effect of 11 cases, 4 cases and 1 case of no effect, and the total effective rate is 98%; 10 patients with hydrofluoric acid burns cure 5 patients, have obvious effect of 3 patients, 1 patient and 1 patient with no effect, and the total effective rate is 90%; among 97 patients with hydrofluoric acid burn, 34 patients with deep III burn and deep III burn area less than 10% are cured, 17 patients with obvious effect, 7 patients with effect and 3 patients with no effect, and the total effective rate is 95%; in 36 patients with deep II degree burns, 31 patients are cured, 2 patients are obviously effective, 2 patients are effective, 1 patient is ineffective, and the total effective rate is 97%.

Typical 4 cases are as follows:

buy a certain, male, 30 years old, live at home and work in the city, polyfluorinated multi-worker, hydrofluoric acid burnt, No. 5 month 15 in 2018 was burnt by hydrofluoric acid when the laboratory test was done in the company laboratory, when sending the treatment, vomit, twitch, cold limbs, head scalp, neck, the skin of the part of the ear is white, the skin of the back is gray yellow, there is coffee blister, the forearm is tawny, part of the skin turns black, the surface is sunken. The diagnosis 1 is hydrofluoric acid burn, the total area is 28%, the depth II is 10%, the depth II is 12%, and the depth III is 6%. The ointment is used for changing the dressing once every day, so that the symptomatic treatment of deep III degree hydrofluoric acid burn infusion by western doctors is assisted, the patients are discharged after 6-10 months in 2018, scars are shallow, the scars are not easy to find, and the patients are very satisfied.

In the second stage of a Xinxin garden in a middle-station area of a home-made Jiaozuo city, a worker of a fluorine increasing company in the Jiaozuo city, No. 6 and 12 in 2017, carelessly makes hydrofluoric acid on a body when working, the company washes with water for about 20 minutes, the company sends the medicine for treatment, the mind is clear, the expression is painful, the person groans continuously, the limbs are cold, the head and the face are not burnt, the right front arm is provided with blisters with different sizes, the envelope paper sample contacted with the hand is partially grayish brown, the skin on the front outer side of two shanks is grey white, 1. hydrofluoric acid burn is diagnosed, the total area is 15 percent, the skin is shallow II 13 percent, and the skin depth III is 2 percent. Necrotic tissues are removed, hexafluoro-ganoderma and calcium gluconate are used for alternately flushing for 15 minutes, calcium gluconate injection with the mass fraction of 2.5% is used for injecting the burn, the dressing change is carried out once a day by using the ointment, and the burn is cured and discharged in 2017, 6 and 28 months. No scar is left, and the patient is satisfied.

The medicine is prepared from Fenggao, women, 23 years old, home-made Jiaozhong city, middle standing shop, village, Jiaozhong city, middle standing district, polyfluorinated multi-worker, No. 6/26 working in 2020, hands carelessly burned by hydrofluoric acid, fingers severely ache, treatment is given, the mind is clear, the expression is painful, 3 finger tips are blackened, the backs of the other palms and hands are red and swollen, the back, the abdomen, the skin on the back sides of shanks, feet and thighs is normal, the head has no deformity, no tenderness and no scalp burn. Eyebrows are present. The ointment has the advantages that eyelid edema of two eyes, eyeball movement flexibility, conjunctival mild hyperemia and edema, perioral skin mucosa edema are diagnosed, 1, hydrofluoric acid burn and deep II 10 percent are diagnosed, necrotic tissues are removed, hexafluoro-ethanol and calcium gluconate are used for alternately flushing for 15 minutes, calcium gluconate injection with the mass fraction of 2.5 percent is injected at the burn, the ointment is used for changing the medicine once every day, No. 7/2 in 2020, no scar is left, and the patient is satisfied completely.

Comparison of 5 with the prior art: in order to further test the treatment effect of the invention, 121 hydrofluoric acid burn patients are selected alternatively, wherein 36 patients which do not use the invention and only use western medicines for treatment are a western medicine group, the western medicine group adopts conventional western medicines for debridement, hexafluoro-Ling, calcium gluconate and hydrofluoric acid for washing, calcium gluconate injection is injected to the burn, compound sulfadiazine zinc gel is smeared on the burn and is given with antibiotics, and III degree burns can not be healed by changing medicines and are treated by surgery; the combination of the present invention and western medicine treatment is used for 52 experimental groups, and the treatment scheme is as the step 1.3; the burn ointment combines the Jingwanhong scald ointment with western medicine treatment, the Jingwanhong group has 33 cases, the normal western medicine is adopted for debridement, the hexafluoroethanol and the calcium gluconate hydrofluoric acid are used for washing, the calcium gluconate injection is used for injecting the burn, the Jingwanhong scald ointment is used for smearing the burn, and the antibiotic is given; the statistical results after 20 days of treatment for all 3 groups were as follows: in the western medicine group, 16 patients with deep III burn and deep III burn area less than 10% cured 0 cases, 10 cases with obvious effect, 5 cases with effect and 1 case with no effect, the cure rate is 0 and the total effective rate is 94%; the patients with deep II degree burns have 20 cases, 3 cases are cured, 15 cases are obviously effective, 1 case is ineffective, the cure rate is 15%, and the total effective rate is 95%. In a test group, 25 patients with deep III burns and deep III burns with the area less than 10 percent have 15 cases of cure, 8 cases of obvious effect, 1 case of effect and 1 case of no effect, the cure rate is 60 percent, and the total effective rate is 96 percent; the patients with deep II degree burns have 27 cases, 20 cases are cured, 4 cases are obviously effective, 2 cases are effective, 1 case is ineffective, the cure rate is 74%, and the total effective rate is 96%. In the Jingwanhong group, 16 patients with deep III burn and deep III burn area less than 10% have 1 case of cure, 10 cases of obvious effect, 4 cases of effect and 1 case of no effect, the cure rate is 6%, and the total effective rate is 94%; the number of patients with deep II degree burns is 17, 4 cases are cured, 10 cases are obviously effective, 2 cases are effective, 1 case is ineffective, the cure rate is 24%, and the total effective rate is 94%.

Conclusion 6

The above statistics fully show that the invention is an effective medicine for treating hydrofluoric acid burn, and has the advantages of short treatment period, remarkable curative effect, high cure rate, greatly reduced scar generation at hydrofluoric acid burn and improved life quality of patients. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.

Claims

1. An ointment for treating hydrofluoric acid burn is characterized by comprising the following components in parts by weight: 15-20g of apocynum venetum, 25-30g of castor bean, 3-5g of leech, 25-30g of star anise, 12-18g of white scallop, 7-9g of tripterygium wilfordii, 12-18g of spreading hedyotis herb, 27-33g of sophora flower rice, 27-33g of angelica dahurica, 90-110g of angelica, 27-33g of dragon's blood, 17-23g of white wax, 17-23g of calomel, 45-55g of liquorice, 45-55g of lithospermum and 550g of vaseline as raw materials, firstly, putting the sophora flower rice into water, wherein the weight ratio of the sophora flower rice to the water is 1: 20, boiling with strong fire, keeping the mixture on slow fire for 30-1 hour, filtering, collecting filtrate, adding water which is 10 times of the sophora flower rice into sophora flower rice dregs, boiling with strong fire, keeping the mixture on slow fire for 30-45 minutes, collecting the filtrate, combining the two filtrates to obtain a mixed solution, adding 0.1 times of lead acetate into the mixed solution, standing for 20-24 hours, centrifuging for 2 times, 5-8 min each time, taking the supernatant to obtain a sophora flower rice water extract stock solution, respectively grinding apocynum venetum, castor bean, leech, anise, fritillary, tripterygium wilfordii and herba hedyotis into fine powder, uniformly mixing, adding the sophora flower rice water extract stock solution, uniformly mixing to obtain a mixture A, respectively grinding the mixture A, the angelica dahurica, the angelica, the dragon's blood, the white wax, the calomel, the liquorice and the lithospermum into fine powder, uniformly mixing, adding vaseline into the mixture B, uniformly mixing to obtain a mixture B, adding the mixture A into the mixture B, and uniformly mixing to obtain the sophora flower rice wine.

2. The ointment for treating hydrofluoric acid burn according to claim 1, which is prepared from the following materials by weight: the preparation method comprises the following steps of firstly putting sophora flower rice into 600ml of water, decocting the sophora flower rice with strong fire until the sophora flower rice is boiled, keeping the sophora flower rice with slow fire for 45 minutes, filtering, collecting filtrate, adding 300ml of water into sophora flower rice dregs, decocting the sophora flower rice with strong fire until the sophora flower rice is boiled, keeping the sophora flower rice with slow fire for 40 minutes, collecting filtrate, combining the two filtrates to obtain a mixed solution, adding 0.1 time of lead acetate into the mixed solution, standing for 22 hours, centrifuging for 2 times, 6min for each time, and 1500 r/min, taking supernatant to obtain a sophora flower rice water extract stock solution, and preparing the sophora flower rice water extract stock solution, the apocynum venetum, the castor bean, leech, the anise, the white scallop, the tripterygium wilfordii, the celastrum wilfordii, 15g of white scallop, 8g of tripterygium wilfordii, 15g of white pepper, 8g of tripterygium wilfordii, 15g of tripterygium wilfordii, 30g of sophora flower rice, 30g of angelica dahurica flower rice, 30g of radix angelicae, 20g of slow fire, 20g of mercurous alba, 20g of mercurous chinensis and 500g of mercurous chinensis are taken as raw materials, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

3. The ointment for treating hydrofluoric acid burn according to claim 1, which is prepared from the following materials by weight: the preparation method comprises the following steps of firstly putting sophora flower rice into 660ml of water, decocting the sophora flower rice to boiling with strong fire, keeping the mixture for 30 minutes, filtering, collecting filtrate, adding 330ml of water into sophora flower rice dregs, decocting the sophora flower rice to boiling with slow fire, keeping the mixture for 30 minutes, collecting filtrate, combining the filtrates to obtain a mixed solution, adding 0.1 time of lead acetate into the mixed solution, standing for 20 hours, centrifuging for 2 times, 7 minutes each time, and 1500 r/min, taking supernatant to obtain sophora flower rice water extract stock solution, and preparing the sophora flower rice water extract stock solution, namely the apocynum venetum, the castor bean, the leech, the anise, the fritillary bulb, the tripterygium wilfordii, 25g of star anise, 12g of white scallop, 12g of white pepper, 12g of white beetroot, 9g of tripterygium wilfordii, 55g of liquorice and 450 parts of vaseline as raw materials, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

4. The ointment for treating hydrofluoric acid burn according to claim 1, which is prepared from the following materials by weight: 20g of apocynum venetum, 25g of castor bean, 3g of leech, 30g of star anise, 18g of white scallop, 7g of tripterygium wilfordii, 18g of oldenlandia diffusa, 27g of sophora flower rice, 33g of angelica dahurica, 110g of angelica, 33g of dragon's blood, 17g of white wax, 23g of calomel, 45g of liquorice, 45g of lithospermum and 550g of vaseline are taken as raw materials to prepare the Chinese medicinal preparation, firstly, the sophora flower rice is taken and put into 540ml of water, decocted with strong fire until boiling, switched to slow fire, kept for 1 hour, filtered, filtrate is collected, 270ml of water is added into sophora flower rice dregs, decocted with strong fire until boiling, switched to slow fire, kept for 45 minutes, filtrate is collected, two filtrates are combined to obtain a mixed solution, lead acetate which is 0.1 time of the mixed solution is added, the mixed solution is kept still for 24 hours, centrifuged for 2 times, each time, at the speed of 8min and 1500 r/min, the supernatant is taken to obtain a raw solution of the Chinese scholartree flower rice aqueous extract, the raw solution, the apocynum venetum, the castor bean, the leech, the Chinese anise, the white scallop, the tripterygium wilfordii, the white scallop, the white pepper, the sophora flower rice, the other, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

5. The ointment for treating hydrofluoric acid burn according to claim 1, which is prepared from the following materials by weight: the preparation method comprises the following steps of firstly putting sophora flower rice into 540ml of water, decocting the sophora flower rice with strong fire until the sophora flower rice is boiled, keeping the sophora flower rice with slow fire for 30 minutes, filtering, collecting filtrate, adding 270ml of water into sophora flower rice dregs, decocting the sophora flower rice with strong fire until the sophora flower rice is boiled, keeping the sophora flower rice with slow fire for 30 minutes, collecting filtrate, combining the two filtrates to obtain a mixed solution, adding 0.1 time of lead acetate into the mixed solution, standing for 20 hours, centrifuging for 2 times, 5 minutes each time for 5 minutes, and 1500 r/min, taking supernatant to obtain a sophora flower rice water extract stock solution, and preparing the apocynum venetum, the castor bean, leech, the anise, the white scallop, the tripterygium wilfordii, the sophora japonica thunbergii, the apocynum venetum, 12g of white scallop, 7g of tripterygium wilfordii, 12g of white flower, 7g of tripterygium wilfordii, 12g of herba polygoni, 12g of celastri, and 450g of vaseline as raw materials, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.

6. The ointment for treating hydrofluoric acid burn according to claim 1, which is prepared from the following materials by weight: 20g of apocynum venetum, 30g of castor bean, 5g of leech, 30g of star anise, 18g of white scallop, 9g of tripterygium wilfordii, 18g of oldenlandia diffusa, 33g of sophora flower rice, 33g of angelica dahurica, 110g of angelica, 33g of dragon's blood, 23g of white wax, 23g of calomel, 55g of liquorice, 55g of lithospermum and 550g of vaseline are taken as raw materials to prepare the Chinese medicinal preparation, firstly, the sophora flower rice is taken and put into 660ml of water, decocted with strong fire until boiling, switched to slow fire, kept for 1 hour, filtered, filtrate is collected, 330ml of water is added into sophora flower rice dregs, decocted with strong fire until boiling, switched to slow fire, kept for 45 minutes, filtrate is collected, two filtrates are combined to obtain a mixed solution, lead acetate which is 0.1 time of the mixed solution is added, the mixed solution is kept still for 24 hours, centrifuged for 2 times, each time, 1500 r/min, the supernatant is obtained, and the mixed solution is obtained to obtain a raw solution, and the raw solution of the sophora flower rice water extract, the apocynum venetum, the castor bean, the leech, the Chinese anise, the white scallop, the tripterygium wilfordii, the sophora flower rice, the black bean, the black sesame, the black bean, Grinding herba Hedyotidis Diffusae into fine powder, sieving with 80 mesh sieve, mixing, adding flos Sophorae Immaturus water extract stock solution, blending to obtain mixture A, grinding radix Angelicae Dahuricae, radix Angelicae sinensis, sanguis Draxonis, Cera chinensis, Calomelas, Glycyrrhrizae radix, and radix Arnebiae into fine powder, sieving with 80 mesh sieve, mixing, adding vaseline, blending to obtain mixture B, adding mixture A into mixture B, and blending to obtain the final product.