CN1054067C

CN1054067C - Medicine for treatment of skin injury and preparation method thereof

Info

Publication number: CN1054067C
Application number: CN 95119650
Authority: CN
Inventors: 冯学中
Original assignee: Individual
Current assignee: Individual
Priority date: 1995-12-04
Filing date: 1995-12-04
Publication date: 2000-07-05
Anticipated expiration: 2015-12-04
Also published as: CN1135344A

Abstract

The present invention relates to a medicine for treatment of skin injure. Extracting solution prepared from traditional Chinese medicines, such as double blossom, weeping forsythiae capsule, angelica, nidus vespae, common cnidium fruit, red peony root, baical skullcap root, danshen root, belvedere fruit, etc. is used as an external application drug for skin, which can eliminate bacteria and viruses on the surface of the skin and improve the partial blood circulation to make the blood stream unobstructed, and consequently, skin pathological changes, such as moth-patch, age pigment, neurodermatitis, psora, etc. are cured. The present invention makes the medicine directly act on affected regions, and therefore, the therapeutic effect is quick, and the use is easy.

Description

The medicine and the preparation method of treatment skin injury

The present invention relates to a kind of medicine that is used for the treatment of skin injury, specifically is a kind of outer liniment of liquid that utilizes Chinese medicine extraction.

Chloasma is a kind ofly to take place light brown or the somber patch is that feature is skin lesion with face, and the women is more than the male.The people is to old, and often long on the skin have tan speckle, and the people claims senile plagues or senile plaque, and reason is that human body can produce the material of a kind of crying " free radical " in metabolic process, i.e. lipofuscin pigment, and this pigment is assembled at human body surface, promptly forms senile plaque.Chloasma is bigger to patient's influence of improving looks, and many patients are worried because of there not being effective therapy, have to abuse cosmetics voluntarily, and it is not only invalid to do like this, has damaged secretion, drainage and the metabolic function of skin on the contrary, has increased the weight of chloasma.The report that uses the hyperfrequency electric knife to cut off pathological tissues was once arranged on the document, yet this operation applies some make up equally with making, and can only remove or cover the diseased region of skin surface, can not fundamentally effect a radical cure source of disease, the generation once more of prevention speckle.Adopt endo-medicine such as LIUWEI DIHUANG TANG, the BAZHEN TANG etc. of supplementing QI and nourishing YIN, the kidney invigorating on the traditional Chinese medical science, treat chloasma and obtained certain curative effect by adjusting viscera function, endocrine regulation, courses of pharmaceuticals is long, curative effect is slow, use inconvenience but take.

The purpose of this invention is to provide a kind of taking stopgap measures and effect a permanent cure, fundamentally treat the local skin tissue and change, curative effect skin fast, easy to use is applied medicinal lotion or ointment outward, and thing---skin is as if health, and its preparation method.

The present invention adopts Chinese medicine allotments such as Flos Lonicerae, Fructus Forsythiae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, the Fructus Kochiae, Nidus Vespae, Radix Scutellariae, Radix Paeoniae Rubra, Fructus Cnidii to form, and its concrete consumption (weight ratio) is:

Flos Lonicerae 5-10% Fructus Forsythiae 10-20%

Radix Angelicae Sinensis 15-30% Radix Salviae Miltiorrhizae 15-30%

Fructus Kochiae 15-30% Nidus Vespae 2-5%

Radix Scutellariae 5-10% Radix Paeoniae Rubra 5-10%

Fructus Cnidii 5-10%

Concrete preparation method of the present invention is:

At first under 70～80 ℃ of temperature Flos Lonicerae, Radix Angelicae Sinensis, Nidus Vespae three flavor Chinese medicines are gently fried in shallow oil twice, fried in shallow oil 15～20 minutes at every turn, decocting liquid is crossed the big screen cloth of 20～30 purposes and is collected filtrate.

Secondly will remain Six-element Chinese medicine decocts twice under 100 ℃ of conditions, and each 20～30 minutes, decocting liquid was also crossed the big screen cloth of 20～30 orders and collected.

Mix two kinds of filtrates, quiescent settling 24 hours takes out the supernatant, adds bottle intermediate package of packing into behind the potassium sorbate of 3 ‰ (W/V) and obtains finished product.

In preparation technology of the present invention, the contained volatile oil composition of Flos Lonicerae, Radix Angelicae Sinensis, Nidusvespae three flavor Chinese medicines is more, and very complicated, and for example the low-boiling point material of Radix Angelicae Sinensis just has kind more than ten.Therefore above-mentioned three flavor Chinese medicines are gently fried in shallow oil under 70～80 ℃ of temperature, can be strengthened drug effect, keep the due effect of medicine.Can notice that the filtration of decocting liquid is to have adopted the big screen cloth of 20～30 purposes in the technology of the present invention, rather than the filter cloth that uses in the common process.This is that these materials play crucial effects for treatment chloasma, senile plaque owing to contain many macromolecular substances in decocting liquid, if use filter cloth to filter, these macromolecular substances can be filtered, and using curative effect can reduce greatly.

General viewpoint is thought, chloasma, senile plaque, neurodermatitis, psoriasis etc. are all relevant with the viscera function imbalance, and particularly due to the endocrine regulation, therefore most of doctors set about treatment from the endocrine regulation systemic-function.Yet we find after deliberation, local skin weakened defensive QI, disharmony between QI and blood, blood-vessel obstructive, skin lose and supports also is morbific main cause, it is damp and hot to be that bacterial virus is invaded, is affected by the cold outward, makes local microcirculation function generation obstacle, thrombosis, so that pathological changes takes place gradually.Therefore, the present invention adopts the Chinese medicine allotment with heat-clearing and toxic substances removing, nourshing blood and promoting blood circulation, dispelling wind for relieving itching effect to make the liquid externally applied liniment and treats skin injury according to theory of Chinese medical science.

In each medicine that the present invention adopts, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, evacuation of pus pain relieving can improve blood circulation, have antibacterial action again; Flos Lonicerae heat-clearing and toxic substances removing, energy eliminating carbuncle deep carbuncle are washed chancre peeling skin heat in blood; Fructus Forsythiae heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, all menses stagnation of QI that can loose are poly-, again thoroughly flesh induce sweat, the heat clearing away ventilation; Fructus Kochiae clearing away heat-damp and promoting diuresis, relieving stranguria by diuresis, dispelling wind for relieving itching have inhibitory action to dermatophytes; Chinese angelica blood supplementing and blood can improve general metabolism, and the speckle pathological process of atherosclerosis is had protective effect; The pain relieving of Radix Paeoniae Rubra clots absorbing, removing heat from blood detumescence have spasmolysis and analgesia, antiinflammatory antiulcer, the effect of sterilization antipyretic; Radix Scutellariae removing the relative excess fire, remove damp and hot, can direct loose smooth muscle, have the antiinflammatory antiallergic action, and the various skin pathomycete had the inhibition ability; Nidus Vespae dispels the wind, detoxicating and killing parasites, generally is used for carbuncle scrofula, the toothache of tinea skin ulcer, rheumatic arthralgia, scall pruritus; Fructus Cnidii warming the kidney to invigorate YANG, cold expelling dispel the wind, removing dampness and killing parasites, have antifungic action.All medicine compatibilities can be eliminated skin surface antibacterial, fungus and virus, improve local blood circulation, and the blood smoothness impels skin function to be restored, and then natural speckle disappears to itch and ends.

The present invention extracts the Chinese medicine allotment and makes the external use liquid liniment, can directly medicine be rubbed wiping at affected part, and effect is rapid, curative effect is fast and easy to use.For chloasma, senile plaque, neurodermatitis, psoriasis etc. health care prevention and regressive effect are arranged all.

Below be two concrete application examples of the present invention:

Embodiment 1:

A, accurately take by weighing Flos Lonicerae 4kg, Radix Angelicae Sinensis 10kg, Nidus Vespae 1.5kg and pack in the multi-function extractor through picking, cut off, cleaning, add water to the medicine submergence, adjust the temperature to 70 ℃, gently fried in shallow oil 15 minutes, gently fried in shallow oil 15 minutes by the water that adds same amount behind the big screen cloth collection of the 20 purposes decocting liquid again, collect decocting liquid twice, discard residue.

B, accurately take by weighing Fructus Forsythiae 6kg, Radix Salviae Miltiorrhizae 10kg, Fructus Kochiae 8kg, Radix Scutellariae 2kg, Radix Paeoniae Rubra 3kg, Fructus Cnidii 4.5kg and pack in the multi-function extractor through picking, cut off, cleaning, the water that adds energy submergence medication amount, be warming up to 100 ℃ of persons of frying in shallow oil 30 minutes, decoct twice altogether, twice decocting liquid is also filtered with the big sieve mesh of 20 orders collect and discard medicinal residues.

C, two kinds of filtrates are mixed, quiescent settling 24 hours is got after the supernatant adds the potassium sorbate dissolving that accounts for liquid 3 ‰ (W/V) bottle intermediate package of packing into.

Embodiment 2:

Flos Lonicerae 9kg, Fructus Forsythiae 15kg, Radix Angelicae Sinensis 15kg, Radix Salviae Miltiorrhizae 15kg, Fructus Kochiae 20kg, Nidus Vespae 5kg, Radix Scutellariae 8kg, Radix Paeoniae Rubra 8kg, Fructus Cnidii 5kg.

Method for making is with embodiment 1.

Claims

1, a kind of external used medicine that is used for the treatment of skin injury is characterized in that being made by following percentage by weight by Flos Lonicerae, Fructus Forsythiae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, the Fructus Kochiae, Nidus Vespae, Radix Scutellariae, Radix Paeoniae Rubra, Fructus Cnidii:

Flos Lonicerae 5-10% Fructus Forsythiae 10-20%

Radix Angelicae Sinensis 15-30% Radix Salviae Miltiorrhizae 15-30%

Fructus Kochiae 15-30% Nidus Vespae 2-5%

Radix Scutellariae 5-10% Radix Paeoniae Rubra 5-10%

Fructus Cnidii 5-10%

2, the preparation method of the described medicine of claim 1 is characterized in that:

A), Flos Lonicerae, Radix Angelicae Sinensis, Nidus Vespae are gently fried in shallow oil twice under 70～80 ℃ of temperature, each 15～20 minutes, collect decocting liquid;

B), all the other Six-element Chinese medicines are decocted twice under 100 ℃ of conditions, each 20～30 minutes, collect decocting liquid;

C), mix a), b) decocting liquid, quiescent settling is got the potassium sorbate that the supernatant adds 3 ‰ (W/V) after 24 hours.

3, according to the preparation method of the described medicine of claim 2, it is characterized in that a), b) in the step collection of decocting liquid be to adopt the big screen filtration of 20～30 purposes to collect.