CN112156151A - External spray for treating burns and scalds and preparation method thereof - Google Patents

External spray for treating burns and scalds and preparation method thereof Download PDF

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CN112156151A
CN112156151A CN202011181686.0A CN202011181686A CN112156151A CN 112156151 A CN112156151 A CN 112156151A CN 202011181686 A CN202011181686 A CN 202011181686A CN 112156151 A CN112156151 A CN 112156151A
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treating
root
external spray
hot water
fire
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黄宪程
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739—Sanguisorba (burnet)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
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    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

The invention discloses an external spray for treating burns and scalds and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. The external spray for treating the scald caused by hot water or fire is prepared from the following raw materials in parts by weight: 55-65 g of cherokee rose root, 55-65 g of radix palmetti preparata, 55-65 g of madder, 55-65 g of golden cypress, 55-65 g of suberect spatholobus stem, 55-65 g of garden burnet root, 55-65 g of bletilla striata and 55-65 g of hiraute shiny bugleweed herb. The invention also discloses a preparation method of the external spray for treating the scald caused by hot water or fire. The external spray for treating the scald caused by the hot water and the fire is prepared from a plurality of traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the effective components of each component, has the effects of clearing away heat and toxic materials, diminishing inflammation, relieving pain, removing putrefaction and promoting granulation, and is used for treating the scald caused by the hot water and the fire.

Description

External spray for treating burns and scalds and preparation method thereof
Technical Field
The invention relates to an external spray for treating burns and scalds and a preparation method thereof, belonging to the technical field of traditional Chinese medicines.
Background
Burn and scald are the changes of human tissues caused by high temperature objects or heat radiation, and the causes of the burn and scald include flame, hot iron, boiling oil, boiled water, soup, electric arc, chemical substances and the like. The clinical manifestations vary according to the degree of injury and the size of the area, while the mild cases have red, swollen, hot, painful or blistered skin as the main clinical manifestations; serious patients can go deep into muscles and bones and cause general changes such as shock and infection, and serious patients can die.
At present, for burns and scalds, the common treatment medicines in the market mainly comprise western medicines containing antibiotics and sulfonamides, and have the following defects: (1) the pain relieving effect is not obvious enough; (2) the stasis-dissipating and swelling-dispersing effects are not strong; (3) the hemostatic effect is not obvious; (4) the inflammation diminishing and granulation promoting speed is slow; the wound healing time is long.
Therefore, an external spray for treating burns and scalds and a preparation method thereof are urgently needed to solve the defects of the prior art.
Disclosure of Invention
The invention aims to provide an external spray for treating burns and scalds. The external spray for treating the scald caused by the hot water and the fire is prepared from a plurality of traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the effective components of each component, has the effects of clearing away heat and toxic materials, diminishing inflammation, relieving pain, removing putrefaction and promoting granulation, and is used for treating the scald caused by the hot water and the fire.
The technical scheme for solving the technical problems is as follows: an external spray for treating burns and scalds is prepared from the following raw materials in parts by weight: 55-65 g of cherokee rose root, 55-65 g of radix palmetti preparata, 55-65 g of madder, 55-65 g of golden cypress, 55-65 g of suberect spatholobus stem, 55-65 g of garden burnet root, 55-65 g of bletilla striata and 55-65 g of hiraute shiny bugleweed herb.
The external spray for treating scald caused by hot water or fire adopts the following raw material introduction:
cherokee rose root, sour and astringent in taste, sweet in flavor, neutral in nature, entering kidney and large intestine channels, has the effects of astringing, arresting bleeding, healing sore, relieving pain and killing parasites.
Giant knotweed rhizome, slightly bitter in taste and slightly cold in nature, enters liver, gallbladder and lung channels, and has the effects of removing dampness and jaundice, clearing away heat and toxic materials, dissipating blood stasis and relieving pain, and eliminating phlegm and relieving cough.
Rubia cordifolia, bitter in taste and cold in nature, enters liver meridian, and has the effects of cooling blood, promoting blood circulation, removing blood stasis and dredging meridians.
Phellodendron bark, cortex Phellodendri, bitter in taste and cold in nature, enters kidney, bladder and large intestine channels and has the effects of clearing heat and drying dampness, purging fire and removing toxicity and removing bone steaming.
Caulis Spatholobi, bitter in taste, slightly sweet in flavor and warm in nature, enters liver and kidney meridians, and has effects of promoting blood circulation, replenishing blood, regulating menstruation, relaxing muscles and tendons and activating collaterals.
Sanguisorba root, bitter, sour and astringent in taste, slightly cold in nature, enters liver and large intestine channels and has the effects of cooling blood, stopping bleeding, detoxifying and healing sores.
Bletilla striata, bitter, sweet and astringent in taste, slightly cold in nature, enters lung, liver and stomach meridians, and has the effects of astringing to stop bleeding, relieving swelling and promoting granulation.
Herba Lycopi, being bitter and pungent in flavor and slightly warm in nature, enters liver and spleen meridians, and has effects of promoting blood circulation, regulating menstruation, removing blood stasis, resolving carbuncle, inducing diuresis and relieving swelling.
The raw materials play a single role, and simultaneously play the efficacies of clearing away heat and toxic material, diminishing inflammation, relieving pain, removing putrefaction and promoting granulation, and are used for treating burns and scalds.
The external spray for treating scald caused by hot water or fire has the beneficial effects that:
(1) the external spray for treating the scald caused by the hot water and the fire is prepared from a plurality of traditional Chinese medicines, has reasonable composition and proper compatibility, fully releases the effective components of each component, has the effects of clearing away heat and toxic materials, diminishing inflammation, relieving pain, removing putrefaction and promoting granulation, and is used for treating the scald caused by the hot water and the fire.
(2) The external spray for treating the scald caused by hot water or fire disclosed by the invention is free from toxic and side effects, quick and lasting in effect, and safe and reliable to use.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the feed is prepared from the following raw materials in parts by weight: 55g of cherokee rose root, 65g of radix salviae miltiorrhizae, 55g of madder, 65g of phellodendron, 55g of suberect spatholobus stem, 65g of garden burnet root, 55g of bletilla striata and 65g of hiraute shiny bugleweed herb.
The adoption of the further beneficial effects is as follows: the external spray for treating the scald caused by hot water and fire is more obvious in drug effect by adopting the mixture ratio of the raw materials.
Further, the feed is prepared from the following raw materials in parts by weight: 60g of cherokee rose root, 60g of radix salviae miltiorrhizae, 60g of madder, 60g of phellodendron, 60g of suberect spatholobus stem, 60g of garden burnet root, 60g of bletilla striata and 60g of hiraute shiny bugleweed herb.
The adoption of the further beneficial effects is as follows: the external spray for treating the scald caused by hot water and fire is more obvious in drug effect by adopting the mixture ratio of the raw materials.
Further, the feed is prepared from the following raw materials in parts by weight: 65g of cherokee rose root, 55g of stir-baked palm root, 65g of madder root, 55g of phellodendron, 65g of suberect spatholobus stem, 55g of garden burnet root, 65g of bletilla striata and 55g of hiraute shiny bugleweed herb.
The adoption of the further beneficial effects is as follows: the external spray for treating the scald caused by hot water and fire is more obvious in drug effect by adopting the mixture ratio of the raw materials.
The second purpose of the invention is to provide a preparation method of an external spray for treating burns and scalds. The external spray for treating the scald caused by hot water or fire has the advantages of simple preparation method, easy operation, wide medicine source, low cost and wide market prospect, and is suitable for popularization and application.
The technical scheme for solving the technical problems is as follows: a preparation method of an external spray for treating scald caused by hot water or fire comprises the following steps:
respectively weighing the following raw materials by weight: 55-65 g of cherokee rose root, 55-65 g of radix palmaris preparata, 55-65 g of madder, 55-65 g of golden cypress, 55-65 g of caulis spatholobi, 55-65 g of garden burnet root, 55-65 g of bletilla striata and 55-65 g of herba lycopi, which are respectively crushed, added into 1.2L-1.8L of white spirit, sealed and soaked for 30d-35d, filtered, and the filtrate is taken, namely the external spray for treating the water and fire scalds.
The preparation method of the external spray for treating scald caused by hot water or fire has the beneficial effects that:
the external spray for treating the scald caused by hot water or fire has the advantages of simple preparation method, easy operation, wide medicine source, low cost and wide market prospect, and is suitable for popularization and application.
The application method of the external spray for treating the scald caused by hot water and fire provided by the invention comprises the following steps:
the external spray for treating scald caused by hot water or fire is taken and externally sprayed on the affected part until the pain disappears, and then the spraying times are gradually reduced.
On the basis of the technical scheme, the invention can be further improved as follows.
Further, the weight of the raw materials is as follows: 55g of cherokee rose root, 65g of radix salviae miltiorrhizae, 55g of madder, 65g of phellodendron, 55g of suberect spatholobus stem, 65g of garden burnet root, 55g of bletilla striata and 65g of hiraute shiny bugleweed herb.
The adoption of the further beneficial effects is as follows: the external spray for treating the scald caused by hot water and fire is more obvious in drug effect by adopting the mixture ratio of the raw materials.
Further, the weight of the raw materials is as follows: 60g of cherokee rose root, 60g of radix salviae miltiorrhizae, 60g of madder, 60g of phellodendron, 60g of suberect spatholobus stem, 60g of garden burnet root, 60g of bletilla striata and 60g of hiraute shiny bugleweed herb.
The adoption of the further beneficial effects is as follows: the external spray for treating the scald caused by hot water and fire is more obvious in drug effect by adopting the mixture ratio of the raw materials.
Further, the weight of the raw materials is as follows: 65g of cherokee rose root, 55g of stir-baked palm root, 65g of madder root, 55g of phellodendron, 65g of suberect spatholobus stem, 55g of garden burnet root, 65g of bletilla striata and 55g of hiraute shiny bugleweed herb.
The adoption of the further beneficial effects is as follows: the external spray for treating the scald caused by hot water and fire is more obvious in drug effect by adopting the mixture ratio of the raw materials.
Further, the pulverized particle size is 100 mesh.
The adoption of the further beneficial effects is as follows: the crushed particle size is 100 meshes, and the beneficial components of the raw materials in the external spray for treating burns and scalds are easier to dissolve out, so that the drug effect is better.
Further, the alcoholic strength of the white spirit is 52 degrees.
The adoption of the further beneficial effects is as follows: the alcohol content is 52 degrees, the beneficial components of the raw materials in the external spray for treating the scald caused by hot water or fire are easier to dissolve out, and the drug effect is better.
Detailed Description
The principles and features of this invention are described below in conjunction with specific embodiments, which are set forth merely to illustrate the invention and are not intended to limit the scope of the invention.
Example 1:
the external spray for treating burns and scalds of the embodiment is prepared from the following raw materials in parts by weight: 55g of cherokee rose root, 65g of radix salviae miltiorrhizae, 55g of madder, 65g of phellodendron, 55g of suberect spatholobus stem, 65g of garden burnet root, 55g of bletilla striata and 65g of hiraute shiny bugleweed herb.
The preparation method of the external spray for treating the scald caused by hot water and fire comprises the following steps:
respectively weighing the following raw materials by weight: 55g of cherokee rose root, 65g of stir-baked palm root, 55g of madder, 65g of golden cypress, 55g of caulis spatholobi, 65g of garden burnet root, 55g of bletilla striata and 65g of eupatorium japonicum, which are respectively crushed to 100 meshes, added into 1.2L of white spirit with the alcohol content of 52 degrees, sealed and soaked for 30 days, and filtered, and the filtrate is taken, namely the external spray for treating the scald caused by water and fire.
Example 2:
the external spray for treating burns and scalds of the embodiment is prepared from the following raw materials in parts by weight: 60g of cherokee rose root, 60g of radix salviae miltiorrhizae, 60g of madder, 60g of phellodendron, 60g of suberect spatholobus stem, 60g of garden burnet root, 60g of bletilla striata and 60g of hiraute shiny bugleweed herb.
The preparation method of the external spray for treating the scald caused by hot water and fire comprises the following steps:
respectively weighing the following raw materials by weight: 60g of cherokee rose root, 60g of radix palmettiae preparata, 60g of madder, 60g of golden cypress, 60g of caulis spatholobi, 60g of garden burnet root, 60g of bletilla striata and 60g of herba lycopi, which are respectively ground to 100 meshes, added into 1.5L of white spirit with the alcoholic strength of 52 degrees, sealed and soaked for 32d, filtered, and the filtrate is taken, namely the external spray for treating the scald caused by water and fire.
Example 3:
the external spray for treating burns and scalds of the embodiment is prepared from the following raw materials in parts by weight: 65g of cherokee rose root, 55g of stir-baked palm root, 65g of madder root, 55g of phellodendron, 65g of suberect spatholobus stem, 55g of garden burnet root, 65g of bletilla striata and 55g of hiraute shiny bugleweed herb.
The preparation method of the external spray for treating the scald caused by hot water and fire comprises the following steps:
respectively weighing the following raw materials by weight: 65g of cherokee rose root, 55g of stir-baked palm root, 65g of madder root, 55g of golden cypress, 65g of suberect spatholobus stem, 55g of garden burnet root, 65g of bletilla striata and 55g of hiraute shiny bugleweed herb, which are respectively crushed to 100 meshes, added into 1.8L of white spirit with the alcoholic strength of 52 degrees, sealed and soaked for 35d, filtered, and the filtrate is taken, namely the external spray for treating the scald caused by water and fire.
And (3) clinical observation:
1. case selection: the 32 patients in the group, aged 3-52 years, are all scalded by hot water and fire.
2. Method of treatment
The spray for external use for treating the scald caused by hot water or fire prepared in example 1, example 2 or example 3 is sprayed on the affected part, and is sprayed when the pain disappears, and then the spraying times are gradually reduced.
3. Clinical symptoms
The definition of the third degree burn and scald is as follows:
and (3) burn of I degree: necrosis is limited to the superficial layer of epidermis, namely the stratum corneum of epidermis, is completely transparent, the damage of granular layer and acanthocyte layer, the basal cell layer (germinal layer) of epidermis is normal, the skin is red and swollen, dry, local allergy and pain.
The II degree is divided into shallow II degree and deep II degree. Superficial II degree lesions deep to the basal cell layer of the epidermis and the superficial layer of the dermis (papillary layer) are formed, exudates are accumulated in the superficial II degree lesions to form subcutaneous blisters due to the increase of capillary permeability, interstitial edema and fibrous tissues can be degenerated, the epidermis is peeled off, and patients feel severe pain because damaged nerve endings are stimulated, and the healing is almost without scars because the dermis is not completely damaged.
Deep II degree burn: the epidermis, the superficial dermis and some of the skin appendages are damaged. The affected part has lost original tissue structure, coagulation necrosis occurs, the necrotic tissue covers the wound surface, the wound surface is healed mainly by the creeping growth and restoration of the residual epithelium of the skin accessory structure and the epidermal cells around the wound area due to the thick necrotic tissue forming crust, and scars are usually formed after the healing.
And (3) III degree burn: the entire skin and its associated structures are completely necrotic, and some may even damage subcutaneous fat, muscle and bone, thus damaging cells and underlying tissues. The motor system appears locally yellow-gray, dry and even forms eschar. For such wounds, the wound should be filled with granulation tissue after the local necrotic tissue falls off or removed by surgery, and scar is formed on the marginal skin. If the area is large, the skin grafting needs to be healed.
4. Standard of care
The effect is shown: after various scalds and wounds are treated, the surface layer of the skin recovers well and is the same as the normal skin.
The method has the following advantages: after various scalds and wounds are treated, skin tissues gradually recover to be normal, the healing time is accelerated, the diameter of ulcer is reduced, and pain disappears.
And (4) invalidation: the improvement standard can not be achieved.
5. Clinical results
Of 32 patients, 24 cases (75%) were effective, 6 cases (18.75%) were effective, 2 cases (6.25%) were ineffective, and the total effective rate was 93.75%.
6. Typical cases
Case 1: tang Dynasty, male age 35, hot water scalded the legs, blisters, peels, red and swollen, localized swelling, identified as superficial III degree scald. The spray for external use for treating scald caused by hot water or fire prepared in the embodiment 1 of the invention is sprayed on the affected part, and is sprayed when the pain disappears, and then the spraying times are gradually reduced. After being taken for 30 days, the medicine is healed without scars. No recurrence occurred in 8 months of follow-up.
Case 2: yin and a certain disease, female, age 52, scald the face with hot water, and it is identified as deep II degree scald and partial III degree scald. The spray for external use for treating scald caused by hot water or fire prepared in the embodiment 2 of the invention is sprayed on the affected part, and is sprayed when the pain disappears, and then the spraying times are gradually reduced. After being taken for 25 days, the medicine is cured without scars. No recurrence occurred in 6 months of follow-up.
Case 3: plum, female, age 52, scald the elbow with hot water, and was identified as III degree scald. The spray for external use for treating the scald caused by hot water and fire, which is prepared in the embodiment 3 of the invention, is sprayed on the affected part, and is sprayed when the pain disappears, and then the spraying times are gradually reduced. After being taken for 20 days, the medicine is healed without scars. No recurrence occurred in 6 months of follow-up.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (10)

1. An external spray for treating burns and scalds is characterized by being prepared from the following raw materials in parts by weight: 55-65 g of cherokee rose root, 55-65 g of radix palmetti preparata, 55-65 g of madder, 55-65 g of golden cypress, 55-65 g of suberect spatholobus stem, 55-65 g of garden burnet root, 55-65 g of bletilla striata and 55-65 g of hiraute shiny bugleweed herb.
2. The external spray for treating burns and scalds as claimed in claim 1, which is prepared from the following raw materials in parts by weight: 55g of cherokee rose root, 65g of radix salviae miltiorrhizae, 55g of madder, 65g of phellodendron, 55g of suberect spatholobus stem, 65g of garden burnet root, 55g of bletilla striata and 65g of hiraute shiny bugleweed herb.
3. The external spray for treating burns and scalds as claimed in claim 1, which is prepared from the following raw materials in parts by weight: 60g of cherokee rose root, 60g of radix salviae miltiorrhizae, 60g of madder, 60g of phellodendron, 60g of suberect spatholobus stem, 60g of garden burnet root, 60g of bletilla striata and 60g of hiraute shiny bugleweed herb.
4. The external spray for treating burns and scalds as claimed in claim 1, which is prepared from the following raw materials in parts by weight: 65g of cherokee rose root, 55g of stir-baked palm root, 65g of madder root, 55g of phellodendron, 65g of suberect spatholobus stem, 55g of garden burnet root, 65g of bletilla striata and 55g of hiraute shiny bugleweed herb.
5. A preparation method of an external spray for treating scald caused by hot water or fire is characterized by comprising the following steps:
respectively weighing the following raw materials by weight: 55-65 g of cherokee rose root, 55-65 g of radix palmaris preparata, 55-65 g of madder, 55-65 g of golden cypress, 55-65 g of caulis spatholobi, 55-65 g of garden burnet root, 55-65 g of bletilla striata and 55-65 g of herba lycopi, which are respectively crushed, added into 1.2L-1.8L of white spirit, sealed and soaked for 30d-35d, filtered, and the filtrate is taken, namely the external spray for treating the water and fire scalds.
6. The preparation method of the external spray for treating the scald caused by hot water or fire according to claim 5, wherein the weight of the raw materials is as follows: 55g of cherokee rose root, 65g of radix salviae miltiorrhizae, 55g of madder, 65g of phellodendron, 55g of suberect spatholobus stem, 65g of garden burnet root, 55g of bletilla striata and 65g of hiraute shiny bugleweed herb.
7. The preparation method of the external spray for treating the scald caused by hot water or fire according to claim 5, wherein the weight of the raw materials is as follows: 60g of cherokee rose root, 60g of radix salviae miltiorrhizae, 60g of madder, 60g of phellodendron, 60g of suberect spatholobus stem, 60g of garden burnet root, 60g of bletilla striata and 60g of hiraute shiny bugleweed herb.
8. The preparation method of the external spray for treating the scald caused by hot water or fire according to claim 5, wherein the weight of the raw materials is as follows: 65g of cherokee rose root, 55g of stir-baked palm root, 65g of madder root, 55g of phellodendron, 65g of suberect spatholobus stem, 55g of garden burnet root, 65g of bletilla striata and 55g of hiraute shiny bugleweed herb.
9. The method for preparing an external spray for treating scald caused by hot water or fire according to any one of claims 5 to 8, wherein the particle size of the pulverized powder is 100 meshes.
10. The preparation method of the external spray for treating the burns and scalds as claimed in any one of claims 5 to 8, wherein the alcoholic strength of the white spirit is 52 °.
CN202011181686.0A 2020-10-29 2020-10-29 External spray for treating burns and scalds and preparation method thereof Withdrawn CN112156151A (en)

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Application publication date: 20210101