CN112119157B - 前列腺特异性膜抗原car及其使用方法 - Google Patents
前列腺特异性膜抗原car及其使用方法 Download PDFInfo
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- CN112119157B CN112119157B CN201980030397.XA CN201980030397A CN112119157B CN 112119157 B CN112119157 B CN 112119157B CN 201980030397 A CN201980030397 A CN 201980030397A CN 112119157 B CN112119157 B CN 112119157B
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- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07K2319/00—Fusion polypeptide
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862639321P | 2018-03-06 | 2018-03-06 | |
| US62/639,321 | 2018-03-06 | ||
| PCT/US2019/020729 WO2019173324A1 (en) | 2018-03-06 | 2019-03-05 | Prostate-specific membrane antigen cars and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112119157A CN112119157A (zh) | 2020-12-22 |
| CN112119157B true CN112119157B (zh) | 2025-01-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980030397.XA Active CN112119157B (zh) | 2018-03-06 | 2019-03-05 | 前列腺特异性膜抗原car及其使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10780120B2 (enExample) |
| EP (2) | EP3762410A4 (enExample) |
| JP (4) | JP7526097B2 (enExample) |
| KR (1) | KR20200130709A (enExample) |
| CN (1) | CN112119157B (enExample) |
| AU (2) | AU2019231205A1 (enExample) |
| CA (2) | CA3093078A1 (enExample) |
| MX (1) | MX2020009272A (enExample) |
| TW (2) | TW201940520A (enExample) |
| WO (2) | WO2019173324A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010099205A1 (en) * | 2009-02-24 | 2010-09-02 | The Trustees Of The University Of Pennsylvania | Methods for treating progressive multifocal leukoencephalopathy (pml) |
| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| DK2943511T3 (da) | 2013-01-14 | 2019-10-21 | Xencor Inc | Nye heterodimeriske proteiner |
| US10858417B2 (en) | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
| KR102689285B1 (ko) | 2014-11-26 | 2024-07-31 | 젠코어 인코포레이티드 | Cd3 및 종양 항원과 결합하는 이종이량체 항체 |
| CN107406512A (zh) | 2014-11-26 | 2017-11-28 | Xencor公司 | 结合cd3和cd38的异二聚体抗体 |
| US10259887B2 (en) | 2014-11-26 | 2019-04-16 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and tumor antigens |
| KR20190020341A (ko) | 2016-06-28 | 2019-02-28 | 젠코어 인코포레이티드 | 소마토스타틴 수용체 2에 결합하는 이종이량체 항체 |
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| US10934336B2 (en) * | 2017-04-13 | 2021-03-02 | The Trustees Of The University Of Pennsylvania | Use of gene editing to generate universal TCR re-directed T cells for adoptive immunotherapy |
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| AU2020231206A1 (en) | 2021-09-23 |
| KR20200130709A (ko) | 2020-11-19 |
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