CN111991530A - Medicine for treating gout and preparation method thereof - Google Patents

Medicine for treating gout and preparation method thereof Download PDF

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Publication number
CN111991530A
CN111991530A CN202010997188.7A CN202010997188A CN111991530A CN 111991530 A CN111991530 A CN 111991530A CN 202010997188 A CN202010997188 A CN 202010997188A CN 111991530 A CN111991530 A CN 111991530A
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medicine
treating gout
maltodextrin
dragon
preparation
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谢显辉
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Guangxi Xiejuntang Technology Co ltd
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Guangxi Xiejuntang Technology Co ltd
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    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents

Abstract

The invention discloses a medicine for treating gout and a preparation method thereof, wherein the medicine comprises the following raw materials in parts by weight: 40-70 g of yellow dragon hulled shell, 40-70 g of cauda equisetifolia, 50-85 g of leech seven, 40-70 g of doggie dragon, 45-70 g of polygala fallax hemsl, 45-75 g of dahurian rhododendron leaf, 40-70 g of august, 40-70 g of elecampane, 45-60 g of goat milk wood, 40-70 g of pangolin scales, 1-5 g of musk, 2-8 g of clove, 10-15 g of sea buckthorn, 8-12 g of liquorice, 15-20 g of longan pulp, 2-9 g of galangal, 4-15 g of maltodextrin, 4-15 g of cassia seed, 8-12 g of pawpaw, 20-30 g of wolfberry fruit and 2-9 g of seville orange flower. The present invention allows the crystals deposited in the relevant parts of the body to differentiate and dissolve and to be excreted from the kidney through the blood circulation. Can achieve the treatment effect in a short time.

Description

Medicine for treating gout and preparation method thereof
Technical Field
The invention relates to the technical field of gout prescriptions, in particular to a medicament for treating gout and a preparation method thereof.
Background
Gout is also called hyperuricemia, has high morbidity, is difficult to cure and has repeated attack, and belongs to metabolic diseases caused by purine metabolic disorder. Gout is mostly generated in middle-aged and elderly people, obese people and brainworkers, and is clinically characterized by hyperuricemia and repeated attack of gouty acute arthritis, tophus deposition, tophaceous chronic arthritis, joint deformity and the like caused by the hyperuricemia, and has the main clinical manifestations of joint red swelling, hot pain, repeated attack and inflexible joint movement. Chronic interstitial nephritis and uric acid renal calculus formation are often caused by kidney involvement. The increase of uric acid in blood can be divided into two categories, primary and secondary. The primary gout is caused by congenital purine metabolic disorder and is hereditary. The secondary gout can be caused by kidney diseases, leukemia, medicines, food and other reasons, and is better to be caused by men and women in menopause. Gout belongs to the category of arthralgia syndrome in traditional Chinese medicine. The treatise on blood syndrome: "gout, general disability, pain of limbs, gout of today's name and arthralgia syndrome of ancient times".
The traditional Chinese medicine for treating gout becomes an important aspect of traditional Chinese medicine clinic and scientific research, the traditional Chinese medicine for treating gout shows certain advantages, but the traditional Chinese medicine for treating gout has low effective rate and long treatment period, and causes great psychological burden and physical pain to patients, so that a medicine for treating gout and a preparation method thereof are designed to solve the problems.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a medicament for treating gout and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
a medicine for treating gout comprises the following raw materials in parts by weight: 40-70 g of yellow dragon hulled shell, 40-70 g of cauda equisetifolia, 50-85 g of leech seven, 40-70 g of doggie dragon, 45-70 g of polygala fallax hemsl, 45-75 g of dahurian rhododendron leaf, 40-70 g of august, 40-70 g of elecampane, 45-60 g of goat milk wood, 40-70 g of pangolin scales, 1-5 g of musk, 2-8 g of clove, 10-15 g of sea buckthorn, 8-12 g of liquorice, 15-20 g of longan pulp, 2-9 g of galangal, 4-15 g of maltodextrin, 4-15 g of cassia seed, 8-12 g of pawpaw, 20-30 g of wolfberry fruit and 2-9 g of seville orange flower.
As a preferable technical scheme of the invention, the feed comprises the following raw materials in parts by weight: 50g of yellow dragon hulled shell, 50g of cauda equisetifolia, 70g of leech seven, 50g of dog dragon, 50g of polygala fallax hemsl, 50g of dahurian rhododendron leaf, 50g of august, 50g of elecampane, 50g of goat milk wood, 50g of pangolin scales, 3g of musk, 6g of clove, 12g of sea-buckthorn, 10g of liquorice, 18g of longan pulp, 6g of galangal, 10g of maltodextrin, 10g of cassia seed, 10g of pawpaw, 25g of wolfberry fruit and 6g of seville orange flower.
A preparation method of a medicine for treating gout comprises the following steps:
s1, removing dust, impurities and non-medicinal parts from the Chinese medicinal materials except the maltodextrin by adopting methods of picking, sorting, winnowing, sieving, brushing and the like, washing in clear water, and drying the cleaned medicinal materials at the temperature of 100 ℃;
s2, slicing the processed traditional Chinese medicines, crushing the slices by a crusher into fine powder of 100-200 meshes, and sieving the fine powder;
s3, adding the crushed medicines into a three-dimensional mixer, uniformly mixing, adding distilled water and maltodextrin to obtain a soft material, and adding the soft material into a drying box for drying;
s4, mixing the soft material and talcum powder uniformly, and tabletting to obtain tablets;
s5, coating the tablets, and then carrying out vacuum sealing packaging to obtain the gout tablet finished product medicine.
In a preferred embodiment of the present invention, in S2, the raw material is crushed and sieved, and most preferably sieved with a 120-mesh sieve.
In a preferable technical solution of the present invention, in S3, the temperature in the drying box is controlled to be 45 to 50 ℃.
In the preferred technical scheme, in the step S4, the inlet air temperature is controlled to be 60-90 ℃ in the coating process, the equipment used in the coating treatment is a sealed efficient coating machine, and the talcum powder is magnesium stearate.
The invention provides a medicine for treating gout and a preparation method thereof, wherein the medicine comprises the following components: the medicine is prepared from hulled Huanglong, Japanese stephania root, leech, small dog dragon, polygala fallax hemsl, dahurian rhododendron leaf, akebia fruit , elecampane, goat milk wood, pangolin scales, musk, clove, sea buckthorn, liquorice, longan pulp, galangal, maltodextrin, cassia seed, pawpaw, medlar and seville orange flower, and has the functions of dissolving stasis, dispelling turbidity, dispelling wind, eliminating dampness, relieving arthralgia, relieving pain, harmonizing stomach and supplementing vital energy.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
Example one
The invention provides a preparation method of a medicine for treating gout, which comprises the following raw materials in parts by weight: 40g of yellow dragon hulled shell, 40g of cauda equisetifolia, 50g of leech seven, 40g of dog bone, 45g of polygala fallax hemsl, 45g of dahurian rhododendron leaf, 40g of august, 40g of elecampane, 45g of goat milk wood, 40g of pangolin scales, 1g of musk, 2g of clove, 10g of sea-buckthorn, 8g of liquorice, 15g of longan pulp, 2g of galangal, 4g of maltodextrin, 4g of cassia seed, 8g of pawpaw, 20g of medlar and 9g of seville orange flower.
The method comprises the following steps:
s1, removing dust, impurities and non-medicinal parts from the Chinese medicinal materials except the maltodextrin by adopting methods of picking, sorting, winnowing, sieving, brushing and the like, washing in clear water, and drying the cleaned medicinal materials at the temperature of 100 ℃;
s2, slicing the processed traditional Chinese medicines, crushing the slices by a crusher into 100-mesh fine powder, and sieving the fine powder;
s3, adding the crushed medicines into a three-dimensional mixer, uniformly mixing, adding distilled water and maltodextrin to obtain a soft material, and adding the soft material into a drying box for drying;
s4, mixing the soft material and talcum powder uniformly, and tabletting to obtain tablets;
s5, coating the tablets, and then carrying out vacuum sealing packaging to obtain the gout tablet finished product medicine.
Example two
The invention provides a preparation method of a medicine for treating gout, which comprises the following raw materials in parts by weight: 50g of yellow dragon hulled shell, 50g of cauda equisetifolia, 70g of leech seven, 50g of dog dragon, 50g of polygala fallax hemsl, 50g of dahurian rhododendron leaf, 50g of august, 50g of elecampane, 50g of goat milk wood, 50g of pangolin scales, 3g of musk, 6g of clove, 12g of sea-buckthorn, 10g of liquorice, 18g of longan pulp, 6g of galangal, 10g of maltodextrin, 10g of cassia seed, 10g of pawpaw, 25g of wolfberry fruit and 6g of seville orange flower.
The method comprises the following steps:
s1, removing dust, impurities and non-medicinal parts from the Chinese medicinal materials except the maltodextrin by adopting methods of picking, sorting, winnowing, sieving, brushing and the like, washing in clear water, and drying the cleaned medicinal materials at the temperature of 100 ℃;
s2, slicing the processed traditional Chinese medicines, crushing the slices by a crusher into 120-mesh fine powder, and sieving the fine powder;
s3, adding the crushed medicines into a three-dimensional mixer, uniformly mixing, adding distilled water and maltodextrin to obtain a soft material, and adding the soft material into a drying box for drying;
s4, mixing the soft material and talcum powder uniformly, and tabletting to obtain tablets;
s5, coating the tablets, and then carrying out vacuum sealing packaging to obtain the gout tablet finished product medicine.
EXAMPLE III
The invention provides a preparation method of a medicine for treating gout, which comprises the following raw materials in parts by weight: 70g of yellow dragon hulled shell, 70g of cauda equisetifolia, 85g of leech seven, 70g of dog dragon, 70g of polygala fallax hemsl, 75g of dahurian rhododendron leaf, 70g of august, 70g of elecampane, 60g of goat milk wood, 70g of pangolin scales, 5g of musk, 8g of clove, 15g of sea-buckthorn, 12g of liquorice, 20g of longan pulp, 9g of galangal, 15g of maltodextrin, 15g of cassia seed, 12g of pawpaw, 30g of wolfberry fruit and 9g of seville orange flower.
The method comprises the following steps:
s1, removing dust, impurities and non-medicinal parts from the Chinese medicinal materials except the maltodextrin by adopting methods of picking, sorting, winnowing, sieving, brushing and the like, washing in clear water, and drying the cleaned medicinal materials at the temperature of 100 ℃;
s2, slicing the processed traditional Chinese medicines, crushing the slices by a crusher into fine powder of 200 meshes, and sieving the fine powder;
s3, adding the crushed medicines into a three-dimensional mixer, uniformly mixing, adding distilled water and maltodextrin to obtain a soft material, and adding the soft material into a drying box for drying;
s4, mixing the soft material and talcum powder uniformly, and tabletting to obtain tablets;
s5, coating the tablets, and then carrying out vacuum sealing packaging to obtain the gout tablet finished product medicine.
Wherein, the ratio of each component in the second embodiment can exert the maximum effect, and is the preferred embodiment.
50 patients with gout are selected, wherein 25 male patients and 25 female patients are 25-35 years old, 36-45 years old, 46-60 years old and 61-70 years old respectively, the patients take 15 granules in one day with 18 days as a treatment course, the patients eat 10 granules for the first time, 2-3 times/day and 5-7 granules/time later, and drinking water is more than 3000 milliliters each time.
After a patient takes the product, the pain is relieved the next day after the medicine is taken, the pain disappears after five days, the patient walks freely after one month, the blood uric acid recovers to the normal value after two months, the disease does not recur until now, 27 patients get better after one treatment course, the patient can be completely cured after two treatment courses, and the cure rate is 100%.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (6)

1. The medicine for treating gout is characterized by comprising the following raw materials in parts by weight: 40-70 g of yellow dragon hulled shell, 40-70 g of cauda equisetifolia, 50-85 g of leech seven, 40-70 g of doggie dragon, 45-70 g of polygala fallax hemsl, 45-75 g of dahurian rhododendron leaf, 40-70 g of august, 40-70 g of elecampane, 45-60 g of goat milk wood, 40-70 g of pangolin scales, 1-5 g of musk, 2-8 g of clove, 10-15 g of sea buckthorn, 8-12 g of liquorice, 15-20 g of longan pulp, 2-9 g of galangal, 4-15 g of maltodextrin, 4-15 g of cassia seed, 8-12 g of pawpaw, 20-30 g of wolfberry fruit and 2-9 g of seville orange flower.
2. The medicine for treating gout according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 50g of yellow dragon hulled shell, 50g of cauda equisetifolia, 70g of leech seven, 50g of dog dragon, 50g of polygala fallax hemsl, 50g of dahurian rhododendron leaf, 50g of august, 50g of elecampane, 50g of goat milk wood, 50g of pangolin scales, 3g of musk, 6g of clove, 12g of sea-buckthorn, 10g of liquorice, 18g of longan pulp, 6g of galangal, 10g of maltodextrin, 10g of cassia seed, 10g of pawpaw, 25g of wolfberry fruit and 6g of seville orange flower.
3. A preparation method of a medicine for treating gout is characterized by comprising the following steps:
s1, removing dust, impurities and non-medicinal parts from the Chinese medicinal materials except the maltodextrin by adopting methods of picking, sorting, winnowing, sieving, brushing and the like, washing in clear water, and drying the cleaned medicinal materials at the temperature of 100 ℃;
s2, slicing the processed traditional Chinese medicines, crushing the slices by a crusher into fine powder of 100-200 meshes, and sieving the fine powder;
s3, adding the crushed medicines into a three-dimensional mixer, uniformly mixing, adding distilled water and maltodextrin to obtain a soft material, and adding the soft material into a drying box for drying;
s4, mixing the soft material and talcum powder uniformly, and tabletting to obtain tablets;
s5, coating the tablets, and then carrying out vacuum sealing packaging to obtain the gout tablet finished product medicine.
4. The method for preparing a medicament for treating gout according to claim 3, wherein in the step S2, the raw materials are crushed and sieved, and the optimal raw material is sieved by a 120-mesh sieve.
5. The method for preparing a drug for treating gout according to claim 3, wherein in the step S3, the temperature in the drying oven is controlled to be 45-50 ℃.
6. The preparation method of a drug for treating gout according to claim 3, wherein in the step S4, the inlet air temperature is controlled to be 60-90 ℃ in the coating process, the equipment used in the coating process is a closed high-efficiency coating machine, and the talc powder is magnesium stearate.
CN202010997188.7A 2020-09-21 2020-09-21 Medicine for treating gout and preparation method thereof Pending CN111991530A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526275A (en) * 2011-12-29 2012-07-04 关秀敏 Pharmaceutical for curing gout and preparation method thereof
CN103690741A (en) * 2013-12-16 2014-04-02 广西南宁百会药业集团有限公司 Pharmaceutical composition for treating gout and gouty arthritis
CN103690710A (en) * 2013-12-23 2014-04-02 广西南宁科冠医药科技开发有限公司 Pharmaceutical composition for treating gout and gouty arthritis
CN103705689A (en) * 2013-12-23 2014-04-09 广西南宁科冠医药科技开发有限公司 Drug composition for treating gout and gouty arthritis
CN107669930A (en) * 2017-11-01 2018-02-09 武汉草根生物医药科技有限公司 It is a kind of to be used to treat tabletting of gout and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526275A (en) * 2011-12-29 2012-07-04 关秀敏 Pharmaceutical for curing gout and preparation method thereof
CN103690741A (en) * 2013-12-16 2014-04-02 广西南宁百会药业集团有限公司 Pharmaceutical composition for treating gout and gouty arthritis
CN103690710A (en) * 2013-12-23 2014-04-02 广西南宁科冠医药科技开发有限公司 Pharmaceutical composition for treating gout and gouty arthritis
CN103705689A (en) * 2013-12-23 2014-04-09 广西南宁科冠医药科技开发有限公司 Drug composition for treating gout and gouty arthritis
CN107669930A (en) * 2017-11-01 2018-02-09 武汉草根生物医药科技有限公司 It is a kind of to be used to treat tabletting of gout and preparation method thereof

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Application publication date: 20201127