CN107496701A - A kind of production of sperm and the formula for treating impotence and premature ejaculation - Google Patents
A kind of production of sperm and the formula for treating impotence and premature ejaculation Download PDFInfo
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- CN107496701A CN107496701A CN201710858872.5A CN201710858872A CN107496701A CN 107496701 A CN107496701 A CN 107496701A CN 201710858872 A CN201710858872 A CN 201710858872A CN 107496701 A CN107496701 A CN 107496701A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
Abstract
The invention belongs to field of medicine preparing technology, specially a kind of production of sperm and the formula for treating impotence and premature ejaculation.The formula includes the raw material of following parts by weight:1 15 parts of silkworm chrysalis, 1 15 parts of oyster, 1 22 parts of ginseng, 1 20 parts of the fruit of Chinese wolfberry, 1 20 parts of mulberry fruit, 1 20 parts of sealwort.The formula can also include raspberry, in parts by weight for:The addition of raspberry is 1 15 parts.Heretofore described formula can be with nourishing and strengthening vital, strong kidney calming heart, tonifying primordial Qi, blood-nourishing production of sperm, stopping leak.Impotence, premature ejaculation are cured mainly, sexual function declines, and has and strengthen physique, antifatigue effect.Curative effect is reliable, has no side effect, and raw material is easy to get, and is easy to take, treats both principal and secondary aspect of disease.Steady quality type is good, and through clinical trial, security is high when it is used, and patient takes safe and non-toxic.
Description
Technical field
The invention belongs to field of medicine preparing technology, specially a kind of production of sperm and the formula for treating impotence and premature ejaculation.
Background technology
Impotence(ED), premature ejaculation(PE)It is the common sex dysfunction disease of adult male.With modern society's rhythm
Accelerate, study, life and the increase of operating pressure, and cause impotence because of the factor such as environmental pollution, bad life style increase,
The incidence of disease and consultation rate of premature ejaculation improve year by year, because impotence is also known as " impotence ", and carry discrimination derogatory sense, to patient with
Huge physiology and psychological pressure are come.
At present, the pharmaceutical preparation for treating this kind of disease both at home and abroad is mostly the blood vessel expansion that medea or influence NO are metabolized of adding to the fun
Agent is opened, though interim use can help by force for the moment, vigour will be exhausted if long-term use of, and damage health.Also there are many Chinese patent drugs
Product occur, but these medicines still have problems with:First, most of this kind of medicine is all to take at that time effectively, and drug withdrawal is
Without effect;In addition, existing medicine just can use effect in the case where must strengthen after taking in external cause stimulation and subjective desire.These medicines are deposited
In short-term effect, it is only capable of solving the problems, such as a period of time, it is impossible to play the purpose of adjustment human endocrine and nervous system.Therefore, open
It is reliable to send out curative effect a kind of, and adverse reaction is few, is easy to take, and the new drug treated both principal and secondary aspect of disease is necessary.
The content of the invention
The present invention is exactly be directed to the deficiencies in the prior art and defect, there is provided a kind of production of sperm and treats impotence and premature ejaculation
Formula.Impotence and premature ejaculation is treated using the formula, production of sperm can be helped, curative effect is reliable, and adverse reaction is few, is easy to take, treats both principal and secondary aspect of disease.
In order to realize above goal of the invention, concrete technical scheme of the invention is as follows:
A kind of production of sperm and the formula for treating impotence and premature ejaculation, it includes the raw material of following parts by weight:
Silkworm chrysalis 1-15 parts, oyster 1-15 parts, ginseng 1-22 parts, fruit of Chinese wolfberry 1-20 parts, mulberry fruit 1-20 parts, sealwort 1-20 parts.
Preferably, the formula also includes raspberry, in parts by weight for:Raspberry 1-15 parts.
As still more preferably, the production of sperm and the formula for treating impotence and premature ejaculation, it includes the raw material of following parts by weight:
13 parts of silkworm chrysalis, 13 parts of oyster, 20 parts of ginseng, 17 parts of the fruit of Chinese wolfberry, 17 parts of mulberry fruit, 18 parts of sealwort, 13 parts of raspberry.
Production of sperm described above and the formula for treating impotence and premature ejaculation, in addition to arginine, in terms of prescription quality 1kg, arginine
Addition be 10mg-250mg/kg.
A kind of method that production of sperm and treatment impotence and premature ejaculation formula prepare composition, it comprises the following steps:
1)Each raw material is weighed in proportion, is crushed respectively, crosses 100 mesh sieves, it is standby;
2)By the silkworm chrysalis after crushing, oyster, ginseng, the fruit of Chinese wolfberry, mulberry fruit, sealwort and raspberry extracting in water twice, for the first time
Add 10 times of decoctings and boil 2h, temperature is 90 DEG C;6 times of decoctings are added into residue for the second time and boil 1h, temperature is 95 DEG C, filters, closes
And decoction liquor twice;
3)By step 2)In obtained decoction liquor concentrated, be concentrated into the medicinal extract that relative density is 1.5, be then dried,
Crush, cross 100 mesh sieves, obtain fine powder.
The method for preparing composition using production of sperm and treatment impotence and premature ejaculation formula above, fine powder is added and prepares different doses by it
Required various customary adjuvants during type, wherein, auxiliary material refers to diluent, disintegrant, excipient, adhesive, lubricant, surface
Activating agent, filler, preservative, stabilizer, flavouring, thickener, the one or more in cosolvent, prepare in conventional manner
Into the conventional peroral dosage form of any one, specially tablet, capsule, microcapsules, granule, pill, powder, oral liquid, dripping pill
Agent, inhibition preparation or controlled release preparation.
Production of sperm described above and formula the answering in preparing production of sperm and treating the medicine of impotence and premature ejaculation for treating impotence and premature ejaculation
With.
Silkworm chrysalis, also referred to as chalcid fly, be the nutriment of high protein, is one of Chinese medicine that can be used as medicine.Silkworm chrysalis is sweet, mild-natured.
Its main component is unrighted acid, glycerine vinegar, a small amount of lecithin, black alcohol, liposoluble vitamin etc..
Oyster, alias are called raw oyster, be in all foods containing zinc most it is abundant (per 100g oysters, the not weight including shell,
Aqueous 87.1%, containing zinc 71.2mg), it is good zinc supplementation food rich in zinc albuminate, can suppressing hyperactive liver for calming endogenous wind yin-nourishing.
Mulberry fruit, also known as mulberries, are the ripening fruits of Moraceae deciduous tree mulberry tree, and mulberries is called sorosis, mulberry jujube, agriculture
The fresh fruit that people likes its ripe is eaten, and sweet juice is more, is one of the fruit of people's often feeding.After it is dried and it is used as medicine, available for long
Sick body is empty, and liver-kidney Yin deficiency, soreness and weakness of waist and knees, the dark tinnitus of mesh, articular instability, dry constipation of intestines, body fluid deficiency blood is few, hectic fever seminal emission, diabetes
Deng.
Sealwort, also known as:Polygonatum sibiricum Redoute, yellow chicken dish, pipe dish, claw ginseng, tendrilleaf solomonseal rhizome, achickenclaw ginseng etc..For HUANGJING ZANYU CAPSULE,
Rhizome it is horizontal walk, cylindric, tubercle expands.Impeller is given birth to, stockless.For a kind of medicinal plant, there is tonifying spleen, the effect of moistening lung and production of body fluid.
Raspberry, it is a kind of xylophyta of rose family rubus, is a kind of fruit, fruit taste is sour-sweet, plant
With delavay raspberry herb on limb.Raspberry has many alias, such as:Raspberry, cover basin, cover the basin certain kind of berries, tree plum, raspberry, the wild certain kind of berries, wood
The certain kind of berries, black Fischer.Raspberry has cultivation in the Northeast, and in the market is more rare.Raspberry plant can be used as medicine, and have multi-medicament
Value, its fruit play the role of tonifying kidney and strengthening yang.Raspberry seed oil belongs to unrighted acid, can promote prostatic secretions hormone.
The positive effect of the present invention is embodied in:
(One)Nourishing and strengthening vital, strong kidney calming heart, tonifying primordial Qi, blood-nourishing production of sperm, stopping leak.
(Two)Impotence, premature ejaculation are cured mainly, sexual function declines, and has and strengthen physique, antifatigue effect.
(Three)Curative effect is reliable, has no side effect, and raw material is easy to get, and is easy to take, treats both principal and secondary aspect of disease.
(Four)The prescription quality stable type is good, and through clinical trial, security is high when it is used, and patient takes safe nothing
Poison.
Embodiment:
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiment to this hair
It is bright to be described in further detail, but the scope that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to following embodiments.With
Raw material in lower embodiment is marketed drugs.
A kind of method that production of sperm and treatment impotence and premature ejaculation formula prepare composition, it comprises the following steps:
1)Each raw material is weighed in proportion, is crushed respectively, crosses 100 mesh sieves, it is standby;
2)By the silkworm chrysalis after crushing, oyster, ginseng, the fruit of Chinese wolfberry, mulberry fruit, sealwort and raspberry extracting in water twice, for the first time
Add 10 times of decoctings and boil 2h, temperature is 90 DEG C;6 times of decoctings are added into residue for the second time and boil 1h, temperature is 95 DEG C, filters, closes
And decoction liquor twice;
3)By step 2)In obtained decoction liquor concentrated, be concentrated into the medicinal extract that relative density is 1.5, be then dried,
Crush, cross 100 mesh sieves, obtain fine powder.
Embodiment 1:
A kind of production of sperm and the formula for treating impotence and premature ejaculation, it includes the raw material of following parts by weight:13 parts of silkworm chrysalis, 13 parts of oyster, people
20 parts of ginseng, 17 parts of the fruit of Chinese wolfberry, 17 parts of mulberry fruit, 18 parts of sealwort.
Embodiment 2:
A kind of production of sperm and the formula for treating impotence and premature ejaculation, it includes the raw material of following parts by weight:8 parts of silkworm chrysalis, 8 parts of oyster, ginseng
10 parts, 8 parts of the fruit of Chinese wolfberry, 8 parts of mulberry fruit, 9 parts of sealwort.
Embodiment 3:
A kind of production of sperm and the formula for treating impotence and premature ejaculation, it includes the raw material of following parts by weight:13 parts of silkworm chrysalis, 13 parts of oyster, people
20 parts of ginseng, 17 parts of the fruit of Chinese wolfberry, 17 parts of mulberry fruit, 18 parts of sealwort, 13 parts of raspberry.
Embodiment 4:
A kind of production of sperm and the formula for treating impotence and premature ejaculation, it includes the raw material of following parts by weight:13 parts of silkworm chrysalis, 13 parts of oyster, people
20 parts of ginseng, 17 parts of the fruit of Chinese wolfberry, 17 parts of mulberry fruit, 18 parts of sealwort, 13 parts of raspberry.
By the formula in embodiment 1 to 3, prepared by the method in embodiment, obtain fine powder.And by the fine powder
Conventionally it is prepared into capsule.
Formula in embodiment 4, carried out by the method in embodiment after being prepared into fine powder, then the fine powder in terms of 1kg
Quality meter, additionally adds arginine into formula, and arginic addition is 200mg/kg.
Present invention treatment 268 clinical reports of impotence and premature ejaculation are as follows:
100 patients of the above are hospital outpatient clients, max age 63 years old, minimal ages 27 years old, wherein, 27-30 year 23
Example, 31-40 year 50;41-50 year 21, more than 51 years old 6, the course of disease is most short 1 month, most long 12 years.Patient selection's standard root
According to《New Chinese medicine guideline of clinical investigations》(1993)First volume of formulation.Patient's main clinical manifestation is impotence, premature ejaculation, head
Dizzy, tinnitus, forgetful, sleepy power, soreness and weakness of waist and knees.
2nd, diagnostic criteria:Penis anorthosis erects not hard, it is impossible to completes sexual intercourse person.
3rd, treatment method
All patients prepare capsule administration according to the formula in the embodiment of the present invention 1,4 tablets each time(Active compound 2g), three times a day,
Warm water takes;2 weeks big 1 courses for the treatment of, it is discontinued after two courses for the treatment of, treats 3 months statistical results of expiring.
4th, curative effect judging standard
According to《New Chinese medicine guideline of clinical investigations》(1993)First volume of formulation.
Cure:Treatment 3 months, 90 ° of telotism >, the 75% of sexual intercourse chance can success;
It is effective:90 ° of erection > after treatment, the 50% of sexual intercourse chance can success;
Effectively:Being erected after treatment has improvement, and more than the 25% of sexual intercourse chance can success;
Invalid, indices are without improvement before and after medication.
5th, result
Healing 57, effective 20, effective 8, invalid 15, total effective rate 85%.
This with can nourishing and strengthening vital, strong kidney calming heart, blood-nourishing production of sperm, available for treating impotence and premature ejaculation.And with strong body
Soul, antifatigue effect.
In addition, the formula in embodiment 2 to embodiment 4 is also subjected to effect detection, preparation method according to above method
It is consistent, patient's selection in each embodiment is also consistent with embodiment 1, and end product is:
Embodiment 2 is formulated:Healing 60, effective 20, effective 7, invalid 13, total effective rate 87%.
Embodiment 3 is formulated:Healing 62, effective 20, effective 8, invalid 10, total effective rate 90%.
Embodiment 4 is formulated:Healing 65, effective 22, effective 5, invalid 8, total effective rate 92%.
Embodiment 5:
Formula, only by the silkworm chrysalis in raw material, ginseng, the fruit of Chinese wolfberry and mulberry fruit, first uses 55vol% with being consistent in embodiment 4
Soaking in Chinese liquor 24h, then will soak it is good after medicinal material dry 12h at a temperature of 70 DEG C after press in specific embodiment method
Method carries out powder processed and follow-up prepare capsule step and prepared.
The capsule obtained in embodiment 5 is subjected to effect detection according to preceding method, detection method is consistent, finally tied
Fruit is:
Embodiment 5:Healing 68, effective 22, effective 5, invalid 5, total effective rate 95%..
Claims (7)
1. a kind of production of sperm and the formula for treating impotence and premature ejaculation, it is characterised in that include the raw material of following parts by weight:
Silkworm chrysalis 1-15 parts, oyster 1-15 parts, ginseng 1-22 parts, fruit of Chinese wolfberry 1-20 parts, mulberry fruit 1-20 parts, sealwort 1-20 parts.
2. production of sperm and the formula for the treatment of impotence and premature ejaculation according to claim 1, it is characterised in that the formula also includes raspberry,
It is in parts by weight:The addition of raspberry is 1-15 parts.
3. production of sperm and the formula for the treatment of impotence and premature ejaculation according to claim 1, it is characterised in that include the original of following parts by weight
Material:13 parts of silkworm chrysalis, 13 parts of oyster, 20 parts of ginseng, 17 parts of the fruit of Chinese wolfberry, 17 parts of mulberry fruit, 18 parts of sealwort, 13 parts of raspberry.
4. production of sperm and the formula for the treatment of impotence and premature ejaculation according to claim 1, it is characterised in that the formula also includes arginine,
In terms of prescription quality 1kg, arginic addition is 10mg-250mg/kg.
5. one kind production of sperm and treatment impotence and premature ejaculation according to any one claim in claim 1 to claim 3 are matched somebody with somebody
The method that side prepares composition, it is characterised in that comprise the following steps:
1)Each raw material is weighed in proportion, is crushed respectively, crosses 100 mesh sieves, it is standby;
2)By the silkworm chrysalis after crushing, oyster, ginseng, the fruit of Chinese wolfberry, mulberry fruit, sealwort and raspberry extracting in water twice, for the first time
Add 10 times of decoctings and boil 2h, temperature is 90 DEG C;6 times of decoctings are added into residue for the second time and boil 1h, temperature is 95 DEG C, filters, closes
And decoction liquor twice;
3)By step 2)In obtained decoction liquor concentrated, be concentrated into the medicinal extract that relative density is 1.5, be then dried,
Crush, cross 100 mesh sieves, obtain fine powder.
6. the method that composition is prepared using production of sperm and treatment impotence and premature ejaculation formula according to claim 5, it is characterised in that:Will be thin
Powder addition prepares various customary adjuvants required during different dosage forms, wherein, auxiliary material refers to diluent, disintegrant, excipient, glues
Mixture, lubricant, surfactant, filler, preservative, stabilizer, flavouring, thickener, one kind or more in cosolvent
Kind, it is prepared into any conventional peroral dosage form, specially tablet in conventional manner, capsule, microcapsules, granule, pill,
Powder, oral liquid, pill, inhibition preparation or controlled release preparation.
7. production of sperm described in any one and the formula for the treatment of impotence and premature ejaculation are preparing production of sperm and treatment impotence morning in claim 1-4
Application in the medicine let out.
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108283701A (en) * | 2018-04-12 | 2018-07-17 | 李军 | A kind of drug and preparation method thereof for promoting male's sexual and treating impotence |
CN108991576A (en) * | 2018-08-06 | 2018-12-14 | 陕西宏达植物化工有限公司 | A kind of preparation method of raspberry powder |
CN110694048A (en) * | 2019-11-05 | 2020-01-17 | 中升共享生物科技(杭州)有限公司 | Raspberry ginseng and medlar tablet and preparation method thereof |
CN110973438A (en) * | 2019-12-13 | 2020-04-10 | 三门峡乐人家食品有限公司 | Oyster and silkworm chrysalis solid beverage and preparation method thereof |
CN112245525A (en) * | 2020-09-11 | 2021-01-22 | 源合盛(吉林)药业有限公司 | Eight-flavor ointment containing oyster, ginseng and penis cervi and preparation method thereof |
CN113116905A (en) * | 2021-04-20 | 2021-07-16 | 北京天玺宝科技有限公司 | A composition for improving male sexual function and continuously improving sexual dysfunction, and its preparation method |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106943586A (en) * | 2017-03-31 | 2017-07-14 | 山东岐伯堂生物科技有限公司 | A kind of male health-care yang-invigorating formulation production method |
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2017
- 2017-09-21 CN CN201710858872.5A patent/CN107496701B/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106943586A (en) * | 2017-03-31 | 2017-07-14 | 山东岐伯堂生物科技有限公司 | A kind of male health-care yang-invigorating formulation production method |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108283701A (en) * | 2018-04-12 | 2018-07-17 | 李军 | A kind of drug and preparation method thereof for promoting male's sexual and treating impotence |
CN108991576A (en) * | 2018-08-06 | 2018-12-14 | 陕西宏达植物化工有限公司 | A kind of preparation method of raspberry powder |
CN110694048A (en) * | 2019-11-05 | 2020-01-17 | 中升共享生物科技(杭州)有限公司 | Raspberry ginseng and medlar tablet and preparation method thereof |
CN110973438A (en) * | 2019-12-13 | 2020-04-10 | 三门峡乐人家食品有限公司 | Oyster and silkworm chrysalis solid beverage and preparation method thereof |
CN112245525A (en) * | 2020-09-11 | 2021-01-22 | 源合盛(吉林)药业有限公司 | Eight-flavor ointment containing oyster, ginseng and penis cervi and preparation method thereof |
CN113116905A (en) * | 2021-04-20 | 2021-07-16 | 北京天玺宝科技有限公司 | A composition for improving male sexual function and continuously improving sexual dysfunction, and its preparation method |
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