CN108283701A - A kind of drug and preparation method thereof for promoting male's sexual and treating impotence - Google Patents
A kind of drug and preparation method thereof for promoting male's sexual and treating impotence Download PDFInfo
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Abstract
The present invention relates to a kind of drugs and preparation method thereof for promoting male's sexual and treating impotence.The drug is formulated by the raw material of following parts by weight：The Poria cocos of 3 18 parts by weight, the coix seed of 3 18 parts by weight, the citron of 3 18 parts by weight, the arillus longan of 5 30 parts by weight, the donkey-hide gelatin of 3 18 parts by weight, the deer whip of 5 30 parts by weight, the Chinese cassia tree of 3 18 parts by weight, the matrimony vine of 12 parts by weight, the cloves of 3 18 parts by weight, the raspberry of 5 30 parts by weight, the fennel of 2 12 parts by weight, the fructus amomi of 2 12 parts by weight, the Chinese yam of 3 18 parts by weight, the Radix Polygalae of 2 12 parts by weight, the peach kernel of 2 12 parts by weight, the earthworm of 3 18 parts by weight, the ginseng of 2 12 parts by weight, the oyster peptide of the eucommia Bark male flower of 4 24 parts by weight and 5 30 parts by weight.This drug is suitble to males, can improve energy, promotes function of male and improves impotence symptom.
Description
Technical field
The present invention relates to a kind of Chinese medicines and preparation method thereof, more particularly to one kind is for promoting male's sexual and treatment sun
Drug of impotence and preparation method thereof belongs to the field of Chinese medicines.
Background technology
Impotence, that is, erectile dysfunction refers to when attempting sexual intercourse, and penis erecting strength is not enough to be inserted into vagina or penis
Erection hardness, which is held time, to be not enough to complete satisfied sexual life, is one of most common sex dysfunction of male.Chinese male
" impotence " (erectile dysfunction (ED)) total prevalence rate has reached 26.1%, and 40 years old or more prevalence is 40.2%, moderate
Patient obviously increases with severe, and the rate of seeking medical advice of patient is only 17%.Male sexual disfunction includes sexual hypoesthesia, erection function
Obstacle, orgasm and Ejaculatory dysfunction, penis weakness dysfunction, wherein erectile dysfunction are most common male's sexuals
Obstacle.
From the angle of modern medicine, the generation of impotence is not only by age, angiocardiopathy, diabetes and hyperlipidemia etc.
Physical disease and sex partner's relationship, the influence of the psychology and environmental factor such as household situation, bad life habits, drug, hand
Art, race, culture, religion and socio-economic factor etc. are also related with the generation of ED.It is broadly divided into psychological and two kinds organic
The cause of disease.The method of western medical treatment impotence mainly has six major class：Psychotherapy, drug therapy, physical therapy, the interior note of penis sponge body
Penetrate vasoactive agent, penis vessel surgery and penile prosthesis merging.Its drug treatment is most commonly seen, western medicine impotence with
Based on steroids and expansion blood vessel class drug, side effect is larger, easily leads to the diseases such as hypertrophy of the prostate, tumour, cannot take for a long time.
In Traditional Chinese Medicine, impotence disease first recorded in《Interior warp》,《Ling Shu Miraculous Pivot or Divine Axis perverse trend cacosplanchnia shape》Piece impotence is referred to as " cloudy
Impotence ",《Plain Questions impotence is discussed》In also known as " flaccid foot " and " muscle impotence ".Think that consumptive disease and heat symptoms caused by an exopathgen are the main reason for causing impotence.
《Ling Shu Miraculous Pivot or Divine Axis muscles along the regular meridians》It points out:" hot then flaccidity of tendon and muscle is vertical not to be received, and impotence does not have to.The Qing Dynasty《Cloudy source stream behind miscellaneous diseases source stream rhinoceros candle external genitalia》In
Also known as：" people of will, the depressed impariment of the liver are lost, edema with the liver involved, which cannot dredge, to be reached, and also impotence is caused not rise.”
The cause of disease of impotence is more complicated, existing unicity, it is also possible to Combination.It can be divided mainly into following side
Face：1. insufficiency of natural endowment, internal lesion caused by overexertion prolonged illness.Inadequate natural endowment is given up completely to natural impulse, sexual strain or masturbation, early marriage, can cause vital essence empty
Damage, the Yang-function insufficiency of kidneyzang and cause impotence.In addition prolonged illness internal lesion caused by overexertion undermines taste, and qi and blood source is insufficient, and penis can be caused to lose and supported into sun
Impotence.2. incoordination of seven emotions.Feelings will is unsuccessful, and think of is intended to excessively, anxiety and rage, then liver dysfunction.Penis gathers incapability, forms impotence.Or
Ponder over excessive, damage heart spleen, insufficiency of vital energy and blood, penis, which loses, supports；Or frightened convulsion, wound do not reach ancestor in heart kidney, qi-movement disturbance, qi and blood
Muscle cannot be made by force, then impotence.3. intemperance of taking food.Overfeeding pure wine savoury, transporting and transforming function of the spleen and stomach is not normal, poly- humidogene heat, damp invasion of lower energizer
Liver kidney, blockage of channel, disturbance of QI-blood penis form impotence.4. exopathogen is invaded.Occupy long wetland or it is damp and hot it is outer invade, pent up Liver Channel, under
Penis or cold-dampness impairment of yang are noted, sun is held back for the moon, sent out as impotence.
Treatment to impotence mostly based on nourishment for vitality, and biases toward more traditionally mostly with kidney treating therapy for its well-established law
Warming and invigorating kidney Yang commonly uses temperature compensation or " heat " property drug, and " heat " also becomes the basic characteristics of establishing-Yang class drug products.But excessive clothes
With temperature compensation or " heat " property drug, taste, burden of liver can be aggravated, leads to the dysfunction of the spleen in transport and the deficiency of qi in middle-jiao, liver, which is lost to dredge, to be reached and pent-up,
Make to be difficult to bear in weak and weary digestive organs for a long time, causes digestive system function disorderly.Pharmacological property delay is difficult in vivo
Excretion, leads to that Light-headedness, heart heat be uncomfortable in chest, lather, and some can also go out nosebleed, such as take constantly, can also injure body, and
Hidden danger is left for other diseases, even results in and the more mends the more empty, aggravates the low of male's sexual.
Invention content
The object of the present invention is to provide a kind of drugs and preparation method thereof for promoting male's sexual and treating impotence.
Preparation-obtained drug is suitble to males, can improve energy, promotes function of male and improves impotence symptom.
The present invention provides a kind of drug for promoting male's sexual and treating impotence, by the raw material of following parts by weight
It is formulated：
The Poria cocos of 3-18 parts by weight, the coix seed of 3-18 parts by weight, the citron of 3-18 parts by weight, 5-30 parts by weight longan
Meat, the donkey-hide gelatin of 3-18 parts by weight, the deer whip of 5-30 parts by weight, the Chinese cassia tree of 3-18 parts by weight, the matrimony vine of 12 parts by weight, 3-18 weight
Part cloves, the raspberry of 5-30 parts by weight, the fennel of 2-12 parts by weight, the fructus amomi of 2-12 parts by weight, 3-18 parts by weight mountain
Medicine, the Radix Polygalae of 2-12 parts by weight, the peach kernel of 2-12 parts by weight, the earthworm of 3-18 parts by weight, the ginseng of 2-12 parts by weight, 4-24 weights
Measure the oyster peptide of the eucommia Bark male flower and 5-30 parts by weight of part.
Further, described to be matched by the raw material of following parts by weight for promoting male's sexual and treating the drug of impotence
It makes：The Poria cocos of 6-12 parts by weight, the coix seed of 6-12 parts by weight, the citron of 6-12 parts by weight, 10-20 parts by weight longan
Meat, the donkey-hide gelatin of 6-12 parts by weight, the deer whip of 10-20 parts by weight, the Chinese cassia tree of 10-20 parts by weight, the matrimony vine of 4-8 parts by weight, 6-12
The cloves of parts by weight, the raspberry of 10-20 parts by weight, the fennel of 4-8 parts by weight, the fructus amomis of 4-8 parts by weight, 6-12 parts by weight
Chinese yam, the Radix Polygalae of 4-8 parts by weight, the peach kernel of 4-8 parts by weight, the earthworm of 6-12 parts by weight, the ginseng of 4-9 parts by weight, 8-16 weights
Measure the oyster peptide of the eucommia Bark male flower and 10-20 parts by weight of part.
Further, described to be matched by the raw material of following parts by weight for promoting male's sexual and treating the drug of impotence
It makes：The Poria cocos of 9 parts by weight, the coix seed of 9 parts by weight, the citron of 9 parts by weight, the arillus longan of 15 parts by weight, 9 parts by weight
Donkey-hide gelatin, the deer whip of 15 parts by weight, the Chinese cassia tree of 9 parts by weight, the matrimony vine of 12 parts by weight, the cloves of 9 parts by weight, 15 parts by weight cover basin
Son, the fennel of 6 parts by weight, the fructus amomi of 6 parts by weight, the Chinese yam of 9 parts by weight, the Radix Polygalae of 6 parts by weight, the peach kernel of 6 parts by weight, 9 weights
Measure the earthworm of part, the ginseng of 6 parts by weight, 12 parts by weight eucommia Bark male flower and 15 parts by weight oyster peptide.
It is including following the present invention also provides a kind of preparation method of the drug for promoting male's sexual and treating impotence
Step：
Step a：Weigh the Poria cocos of 3-18 parts by weight, the coix seed of 3-18 parts by weight, 3-18 weight respectively in parts by weight
The citron of part, the meat of the arillus longan of 5-30 parts by weight, the donkey-hide gelatin of 3-18 parts by weight, the deer whip of 5-30 parts by weight, 3-18 parts by weight
Osmanthus, the matrimony vine of 12 parts by weight, the cloves of 3-18 parts by weight, the raspberry of 5-30 parts by weight, the fennel of 2-12 parts by weight, 2-12 weights
Measure the fructus amomi of part, the Chinese yam of 3-18 parts by weight, the Radix Polygalae of 2-12 parts by weight, the peach kernel of 2-12 parts by weight, 3-18 parts by weight ground
The oyster peptide of dragon, the ginseng of 2-12 parts by weight, the eucommia Bark male flower of 4-24 parts by weight and 5-30 parts by weight is as raw material for standby；
Step b：First respectively by donkey-hide gelatin, ginseng and deer whip drying and crushing to 120-200 targeted fine powders, then by Poria cocos, Job's tears
Benevolence, citron, arillus longan, Chinese cassia tree, matrimony vine, cloves, raspberry, fennel, fructus amomi, Chinese yam, Radix Polygalae, peach kernel and eucommia Bark male flower mixing add
Enter after the water that 5-10 times of its total weight is measured decocts twice respectively, the decocting liquid and filtration that merge twice obtain the first filtrate, 80 DEG C-
First filtrate is concentrated at 85 DEG C and obtains the first clear cream, and ethyl alcohol is added into first clear cream makes containing for first clear cream
Alcohol amount reaches 55%~80%, then recycles ethyl alcohol after standing 24 hours, the second clear cream is concentrated to give at 50 DEG C -55 DEG C, then will
Second clear cream and ginseng, deer whip, donkey-hide gelatin, oyster peptide and the ground dragon protein fine powder mixing after crushing and drying, then be crushed to
After 120-200 targeted fine powders, pharmaceutically acceptable auxiliary material is added, pharmaceutically acceptable arbitrary dosage form is made.
Further, the described first time decocted was 1.5-2 hours, and described second time decocted is 0.5-1
Hour.
Further, the relative density of first clear cream is 1.08-1.10.
Further, the relative density of second clear cream is 1.30-1.32.
Further, the pharmaceutically acceptable auxiliary material includes starch, sucrose, lactose, mannitol, silicon derivative, fibre
The plain class of dimension and its derivative, alginates, gelatin, polyvinylpyrrolidone, glycerine, POLYSORBATE 80, agar, calcium carbonate, calcium bicarbonate,
In surfactant, polyethylene glycol, cyclodextrin, beta-cyclodextrin, phospholipid material, talcum powder, calcium stearate and magnesium stearate
It is one or more of.
Further, the dosage form of the drug be tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule,
Hard capsule, soft capsule, oral solution, buccal tablet, granule, pill, powder, paste, sublimed preparation or ointment.
Further, the dosage form of the drug be tablet, capsule, oral solution, buccal tablet, granule, pill, powder,
Suspension, pulvis.Preferred Chinese medicine preparation is capsule, tablet, granule.
Specific implementation mode
It is considered herein that impotence is all because indulging in carnal pleasure without restraint and masturbation, or because worrying beyond measure, or it is impairment of the kidney due to fear is not released, causes
Kidney is trembled with fear spleen deficiency, and edema with the liver involved is strongly fragrant to be fallen into, and cannot rise hair, angry deficiency, and is caused penis to wither and soft do not lifted.The cause of disease is cold for the wet kidney of spleen, and edema with the liver involved is strongly fragrant to be fallen into
It is caused.Liver governing tendons, penis is poly- by all muscle, name penis, and the wet kidney of spleen is cold, and edema with the liver involved is strongly fragrant to be fallen into, therefore penis withers and soft do not lift.Treatment is with strong
Spleen relaxes based on liver, and kidney-replenishing.
The present invention selects a variety of integration of drinking and medicinal herbs Chinese medicines, the effect of to reach invigorating spleen and soothing liver, grow benefiting essence-blood, while being aided with temperature compensation
Medicinal material tonifying kidney and strengthening yang.Mild soft and moist without the dry strong disadvantage of general medea, invigorating the spleen to clear away damp pathogen, soothing the liver blood-nourishing grow and fill out kidney essense, Bu Shen Zhuang
Sun, invigorating spleen and soothing liver achieve the purpose that improve improvement of sexual function impotence symptom with invigorating kidney yang.
The present invention has the characteristics that curative for effect, safe ready, has no toxic side effect and cheap.
Drug action mechanism in the present invention is as follows：
Poria cocos is sweet in flavor, light, mild-natured.The thoughts of returning home, lung, spleen, kidney channel.With clearing damp and promoting diuresis, invigorating the spleen effect.《Book on Chinese herbal medicine is just》：It can profit
Key dries, and turbid promote the production of body fluid is led in the then happy intelligence development of sharp key；It dries, dry spleen of relieving oedema or abdominal distension through diuresis or purgation, bowl spares stomach invigorating；Eradicates frightened epilepsies, thick intestines and internal organs of the body, control phlegm it
This, helps the drop of medicine.There is micro-sweet with its taste, therefore says yang-tonifying.
Coix seed is sweet in flavor, light, cool in nature.Returns spleen, stomach, lung channel, advantageous water penetration is wet, invigorating the spleen to arrest diarrhea, eliminating impediment effect.《Book on Chinese herbal medicine
Detailed outline》：The bright medicine of coix seed sun, energy invigorating the spleen, beneficial stomach.
Elscholtiza acrid flavour, hardship, acid, temperature.Return liver, spleen, lung channel.With dispersing stagnated hepatoqi, in wide, the effect of resolving sputum.《Book on Chinese herbal medicine is again
Newly》：Soothing the liver Shu Yu, manages lung qi, and promoting menstruation Li Shui controls waist tinea pedis.
Arillus longan is sweet in flavor, warm-natured.The thoughts of returning home, the spleen channel.Tonifying heart and spleen, nourishing blood and tranquilization.《Book on Chinese herbal medicine is looked for the truth》：" the sweet temperature of longan smell,
It is similar to jujube, but this sugariness is heavier, profit gas is especially more, among tonifying Qi, and more has the power enriched blood more.
Colla Corii Asini nourishing blood enriching yin, moisturizes, hemostasis.For blood deficiency chlorosis, dizziness palpitaition, dysphoria and insomnia, xeropulmonary cough.
Deer whip is sweet in flavor, salty, warm-natured.Return liver, kidney, bladder warp.《Traditional Chinese Medicine in Sichuan will》：Warm-natured, taste is salty pungent, nontoxic；Enter liver,
Kidney, bladder three pass through；Impotence, kidney deficiency syrigmus are controlled, married woman's cold uterus fails to be impregnated for a long time, chronic testis inflammation.
Chinese cassia tree acrid flavour, sweet, extremely hot in nature.Return kidney, spleen, the heart, Liver Channel.There are mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, Wen Tong
The effect of passages through which vital energy circulates.《Medicine origin》：Lower burnt deficiency is mended, chronic diseases and exterior deficiency spontaneous perspiration are controlled.
Fruit of Chinese wolfberry sweet and neutral.Return liver and kidney channel.For the sweet flat matter profit of syndrome of yin deficiency of liver and kidney this product, flat filling liver kidney has strengthening by means of tonics
Effect, all cards of the deficiency of liver-yin and kidney-yin can be applied.
Cloves is acrid in flavour and warm in nature.Returns spleen, stomach, lung, kidney channel.Inverse, eliminating cold to stop pain, warming kidney and enhancing yang drop in middle benefit gas.Enter kidney channel, energy warm kidney helps
Sun controls impotence due to deficiency of the kidney and Gong Leng.
Raspberry is sweet in flavor, sour, warm-natured.Return liver, kidney, bladder warp.For emission and spermatorrhea, enuresis frequent micturition, impotence and premature ejaculation, mesh is dark
It is dim-sighted.《Explaining abstruseness of the canon of materia medica》：" raspberry, it is sweet to put down into kidney, play a sun and control impotence, controlling nocturnal emission with astringent drugs take the photograph it is excessive, strong kidney and without it is scorching it is partially, controlling nocturnal emission with astringent drugs and nothing
Doubt puckery evil, the product of gold and jade.”
Fennel is warm-natured, acrid flavour, returns liver,kidney,spleen, stomach.Function temperature liver kidney, warm stomach gas dissipate plug knot, eliminating cold to stop pain, qi-regulating
And stomach.
Fructus amomi acrid flavour, property are wet.Returns spleen, stomach, kidney channel.There is dampness elimination appetizing, it is warming spleen and stopping diarrha, the effect of regulating the flow of vital energy antiabortive.《Book on Chinese herbal medicine converges
Speech》：The gentle medicine of middle benefit gas.If the gas stalk of the part of the body cavity above the diaphragm housing the heart and lungs is inverse without under, the gas of lower coke is curbed without upper, the airsetting of middle coke gather without
It relaxes, controls it with fructus amomi, prove effective most prompt.
Chinese yam is sweet, flat, nontoxic.Returns spleen, lung, kidney channel.《Sheng Nong's herbal classic》Calling it, " main strong middle qi-restoratives removes fever and chills perverse trend, mends
Middle benefiting energy, long muscle, long term usage normal hearing and eyesight "；((Japan hanako materia medica》Say that it " helps the five internal organs, muscles and bones, long will to calm the nerves living, cures mainly and let out
Essence is forgetful ".
It is Radix Polygalae bitter, pungent, warm-natured.The thoughts of returning home, kidney, lung channel.Tranquilize the mind and promote the intelligence, Xie Yu.《Haigoushen》：It controls the mind to be good for the spring, heavily fortified point is strong
Yang Dao.Main dream is evil.
Peach kernel bitter, sweet, flat.The thoughts of returning home, liver, large intestine channel.Promoting blood circulation.
Ginseng nature and flavor are sweet, slight bitter, put down.Returns spleen, lung, the heart channel of Hang-Shaoyin.With reinforcing vital energy, veins takes off admittedly reinforces the spleen to benefit the lung, and promotes the production of body fluid,
The effect of tranquilizing the mind.Can treat it is physically weak to be taken off, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung breathes with cough, injury thirst, Heat Diabetes, and prolonged illness is empty
It is thin, insomnia of palpitating with fear, impotence Gong Leng；Heart failure, cardiogenic shock etc..
Earthworm protein extraction contains clostridiopetidase A, fibrinolysin, Lumbrokinase, activation of fibrinolysis albumen (FA albumen), core from earthworm
The Multiple components such as acid, trace element, molecular weight belong to short chain small-molecule substance in 5000-10000.It can dissolve it is fresh and
Oldness thrombus improves the anticoagulating activity of human body itself, can activate the differentiation characteristic of vascular endothelial cell, gets through passages through which vital energy circulates, promotes
Capilary regenerates, and establishes offshoot circulation.
Eucommia Bark male flower contains natural plant composition, a large amount of rosin element diglucoside and geniposide, has good
Prevent the effect that sexual desire declines, the common adrenal system hypofunction of " kidney-yang deficiency " patient, Cortex Eucommiae itself has good excitement again
Pituitary Adrenalcortical system enhances the effect of adrenal cortex function, and wherein Zn content reaches 51mg/100g, can improve man
Property few essence, weak essence or nonliquefaction of semen symptom.
Oyster evidence《Compendium of Materia Medica》It records：" men and women's qi and blood is mended in raw oyster, governance wasting, establishing-Yang, removing toxic substances, is enabled skin delicate, is prevented
Aging." several mineral materials and trace element are rich in oyster meat, wherein calcium content is 40-94.04mg/g, iron 5.50-
8.00mg/g, selenium 49.00mg/g, zinc 22.54mg/g.Content of taurine is 50.6mg/ in oyster meat (dry product) extract
g；Oyster peptide can effectively improve level of serum testosterone, enhance male's sexual.Simultaneously have adjust body physiological function and be machine
Body improves the dual function of nutrition.
Poria cocos, coix seed invigorating the spleen excreting dampness in the present invention；Citron, arillus longan, donkey-hide gelatin blood-nourishing is soothing the liver, and liter is fallen into；Deer whip, matrimony vine, fourth
Fragrant, raspberry warming kidney and enhancing body；In Chinese cassia tree temperature, " it is insufficient mending the gate of vitality, boosting source of fire for eliminating abundance of yin ", warm aid yang qi；Fructus amomi warms up the spleen row stasis of blood, and Chinese yam is built
Middle qi-restoratives；Ginseng qi-tonifying rises clear, benefiting qi and raising yang；Radix Polygalae enters heart kidney two warp, can antitoxic heart-soothing and sedative, restoring normal coordination between heart and kidney；Peach kernel promoting blood circulation promoting circulation of blood,
It is aided with ground dragon protein and promotes capilary regeneration, establishes offshoot circulation, promote the congested ability of penis；Eucommia Bark male flower, oyster peptide increase
Strong male's sexual prevents hyposexuality, and wherein eucommia Bark male flower, oyster peptide contains trace element zinc, can improve the few essence of male, weak essence
Or nonliquefaction of semen symptom.Fennel seeds enter liver kidney, draw all medicine downlinks, guiding fire to origin.All medicine compatibilities, invigorating spleen and soothing liver grow benefiting essence-blood,
Tonifying kidney and strengthening yang acts on, giving consideration to both the incidental and fundamental, and based on kidney tonifying, and bowl spares had and rushed down, and benefits is helped to rush down with supporting the first day after tomorrow, then temper it is strong transport,
Irritability dredge reach, kidney qi fills Shengs, negative and positive coordination.
Compared with the prior art, the present invention has the following advantages：The present invention has soothing liver and strengthening spleen, tonifying kidney and benefiting sperm, enriching yin controlling nocturnal emission with astringent drugs
The effect of, soothing liver and strengthening spleen warm kidney, three is dirty with mending, and the five internal organs are logical to be adjusted, significant in efficacy, be suitable for irritability do not dredge, the dysfunction of the spleen in transport, kidney qi not
Impotence caused by foot, premature ejaculation securely and reliably have no toxic side effect, and are worthy of popularization.
Excellent effect in order to better illustrate the present invention, provides following embodiment：
Embodiment 1
The present embodiment is the capsule being processed by the material medicine of following parts by weight：
9 parts by weight of Poria cocos, 9 parts by weight of coix seed, 9 parts by weight of citron, 15 parts by weight of arillus longan,
9 parts by weight of donkey-hide gelatin, 15 parts by weight of deer whip, 9 parts by weight of Chinese cassia tree, 12 parts by weight of matrimony vine,
9 parts by weight of cloves, 15 parts by weight of raspberry, 6 parts by weight of fennel, 6 parts by weight of fructus amomi,
9 parts by weight of Chinese yam, 6 parts by weight of Radix Polygalae, 6 parts by weight of peach kernel, 9 parts by weight of earthworm,
6 parts by weight of ginseng, 12 parts by weight of eucommia Bark male flower, 15 parts by weight of oyster peptide
First take donkey-hide gelatin, ginseng and deer whip drying and crushing to 180 targeted fine powders, then take Poria cocos, coix seed, citron, arillus longan,
Chinese cassia tree, matrimony vine, cloves, raspberry, fennel, fructus amomi, Chinese yam, Radix Polygalae, peach kernel and eucommia Bark male flower add the water of 10 times of amounts of its total weight
It decocts respectively twice, 1.5 hours for the first time, second 1 hour, merges decocting liquid twice, filtration concentrates filtrate to phase at 80 DEG C
The clear cream for being 1.08 to density, adding ethyl alcohol makes the alcohol content of clear cream reach 70%, ethyl alcohol is recycled after standing 24 hours, 50
The clear cream that relative density is 1.30 is concentrated at DEG C, then by clear cream and ginseng, deer whip, donkey-hide gelatin, oyster peptide and ground dragon protein fine powder
Mixing is dried, crushed into 180 targeted fine powders, 10 parts by weight of magnesium stearate and the granulation of 2 parts by weight of silica is added, and be packed into
Capsule.Every fills 0.4 gram, and usually half an hour is oral before meals, and warm water is sent down, one time 4-10,3 times a day, three months are one
A course for the treatment of.
Patient 1, man, 30 years old.Private prosecution：Impotence 3 years, sexual desire are cold, and the several months has sexual intercourse reluctantly, and soft difficulty of withering enters, and one touches and lets out, greatly
Dropping sweat causes goodwill as between spouses to get along well.Repeatly through treatment, effect do not show, and still impotence is not lifted, when sense tiredness it is powerless.Take this implementation
Case product, 5 tablets each time, 3 times a day, impotence, premature ejaculation are clearly better after 1 course for the treatment of, and energy is promoted；Continue to take 1
After a course for the treatment of, premature ejaculation has been cured, impotence unobvious, energetic, without other significant discomforts.Now press daily 2,3 times a day after
Continuous to take, love life quality is obviously improved improvement.
Embodiment 2
The present embodiment is the tablet being processed by the material medicine of following parts by weight：
9 parts by weight of Poria cocos, 9 parts by weight of coix seed, 9 parts by weight of citron, 15 parts by weight of arillus longan,
9 parts by weight of donkey-hide gelatin, 15 parts by weight of deer whip, 9 parts by weight of Chinese cassia tree, 12 parts by weight of matrimony vine,
9 parts by weight of cloves, 15 parts by weight of raspberry, 6 parts by weight of fennel, 6 parts by weight of fructus amomi,
9 parts by weight of Chinese yam, 6 parts by weight of Radix Polygalae, 6 parts by weight of peach kernel, 9 parts by weight of earthworm,
6 parts by weight of ginseng, 12 parts by weight of eucommia Bark male flower, 15 parts by weight of oyster peptide
First take donkey-hide gelatin, ginseng and deer whip drying and crushing to 150 targeted fine powders, then take Poria cocos, coix seed, citron, arillus longan,
Chinese cassia tree, matrimony vine, cloves, raspberry, fennel, fructus amomi, Chinese yam, Radix Polygalae, peach kernel and eucommia Bark male flower add the water of 10 times of amounts of its total weight
It decocts respectively twice, 1.5 hours for the first time, second 1 hour, merges decocting liquid twice, filtration concentrates filtrate to phase at 85 DEG C
The clear cream for being 1.10 to density, adding ethyl alcohol makes the alcohol content of clear cream reach 70%, ethyl alcohol is recycled after standing 24 hours, 55
The clear cream that relative density is 1.30 is concentrated at DEG C, then by clear cream and ginseng, deer whip, donkey-hide gelatin, oyster peptide and ground dragon protein fine powder
Mixing is dried, crushed into 150 targeted fine powders, and 10 parts by weight of lactose, 3 weight of 3 parts by weight of microcrystalline cellulose and magnesium stearate is added
Finished product is made in part granulation, tabletting.Every 0.4 gram, usually half an hour is oral before meals, and warm water is sent down, one time 2~5, one day 3
Secondary, three months as a treatment course.
Patient 2, and man, 36 years old, spiritlessness and weakness, body was become thin, sallow complexion, usually anorexia and loose stool, had masturbation history for many years, property
Easy premature ejaculation when friendship has sexual intercourse only two or three minutes every time for many years not at improvement.Taking kidney-nourishing yang-strengthening medicine has no that illness changes more
It is kind.Take the implementation case product.4 tablets each time, 3 times a day, patient's body-sensing feels that freely, food of receiving increases from head to foot after taking 20
Add, has crossed a sexual life after January of taking medicine, probably had seven or eight minutes, no premature ejaculation.It is energetic after taking 1 course for the treatment of, no loose stool,
Sexual life can be kept one week 2 times, about 10 minutes each time, no premature ejaculation.
Embodiment 3
The present embodiment is the granule being processed by the material medicine of following weight：
9 parts by weight of Poria cocos, 9 parts by weight of coix seed, 9 parts by weight of citron, 15 parts by weight of arillus longan,
9 parts by weight of donkey-hide gelatin, 15 parts by weight of deer whip, 9 parts by weight of Chinese cassia tree, 12 parts by weight of matrimony vine,
9 parts by weight of cloves, 15 parts by weight of raspberry, 6 parts by weight of fennel, 6 parts by weight of fructus amomi,
9 parts by weight of Chinese yam, 6 parts by weight of Radix Polygalae, 6 parts by weight of peach kernel, 9 parts by weight of earthworm,
6 parts by weight of ginseng, 12 parts by weight of eucommia Bark male flower, 15 parts by weight of oyster peptide
First take donkey-hide gelatin, ginseng and deer whip drying and crushing to 200 targeted fine powders, then take Poria cocos, coix seed, citron, arillus longan,
Chinese cassia tree, matrimony vine, cloves, raspberry, fennel, fructus amomi, Chinese yam, Radix Polygalae, peach kernel and eucommia Bark male flower add the moisture of 8 times of amounts of its total weight
It does not decoct twice, 2 hours for the first time, second 0.5 hour, merges decocting liquid twice, filtration concentrates filtrate to opposite at 82 DEG C
The clear cream that density is 1.10, adding ethyl alcohol makes the alcohol content of clear cream reach 70%, ethyl alcohol is recycled after standing 24 hours, at 55 DEG C
Under be concentrated into the clear cream that relative density is 1.32, then clear cream and ginseng, deer whip, donkey-hide gelatin, oyster peptide and ground dragon protein fine powder are mixed
It is even, 200 targeted fine powders are dried, crushed into, 6 parts by weight of sucrose and 12 parts by weight of soluble starch are added, 50% ethyl alcohol system is used in combination
Grain packs after dry to obtain the final product.Warm boiled water, one time 1-3 bags, 3 times a day, three months are as a treatment course.
Patient 3, and man, 27 years old, premature ejaculation more than 1 year was depressed, when private prosecution desire from, male sexuality is easily lifted, and faces room premature ejaculation, when
Have erection cannot, or sometimes can, but be unable to having sexual intercourse thing.Take the implementation case product.It 2 bags every time, 3 times a day, takes medicine 20
Male sexuality is gradually lifted afterwards, and remaining disease is gradually delayed.Medication male sexuality energy on the 30th is manageed it 3 minutes, and male sexuality is multiple normal after 1 course for the treatment of of taking medicine, and all diseases, which are known, removes.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all the present invention spirit and
Within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of drug for promoting male's sexual and treating impotence, which is characterized in that by the raw material of following parts by weight
It is formulated：
The Poria cocos of 3-18 parts by weight, the coix seed of 3-18 parts by weight, the citron of 3-18 parts by weight, 5-30 parts by weight arillus longan,
The donkey-hide gelatin of 3-18 parts by weight, the deer whip of 5-30 parts by weight, the Chinese cassia tree of 3-18 parts by weight, the matrimony vine of 12 parts by weight, 3-18 parts by weight
Cloves, the raspberry of 5-30 parts by weight, the fennel of 2-12 parts by weight, the fructus amomi of 2-12 parts by weight, 3-18 parts by weight Chinese yam,
The Radix Polygalae of 2-12 parts by weight, the peach kernel of 2-12 parts by weight, the earthworm of 3-18 parts by weight, the ginseng of 2-12 parts by weight, 4-24 weight
The oyster peptide of the eucommia Bark male flower and 5-30 parts by weight of part.
2. the drug as described in claim 1 for promoting male's sexual and treating impotence, which is characterized in that by following heavy
The raw material of amount number is formulated：The Poria cocos of 6-12 parts by weight, the coix seed of 6-12 parts by weight, the citron of 6-12 parts by weight, 10-
The arillus longan of 20 parts by weight, the donkey-hide gelatin of 6-12 parts by weight, the deer whip of 10-20 parts by weight, the Chinese cassia tree of 10-20 parts by weight, 4-8 weight
Part matrimony vine, the cloves of 6-12 parts by weight, the raspberry of 10-20 parts by weight, the fennel of 4-8 parts by weight, 4-8 parts by weight sand
Benevolence, the Chinese yam of 6-12 parts by weight, the Radix Polygalae of 4-8 parts by weight, the peach kernel of 4-8 parts by weight, the earthworm of 6-12 parts by weight, 4-9 weight
The oyster peptide of the ginseng of part, the eucommia Bark male flower and 10-20 parts by weight of 8-16 parts by weight.
3. the drug as claimed in claim 2 for promoting male's sexual and treating impotence, which is characterized in that by following heavy
The raw material of amount number is formulated：The Poria cocos of 9 parts by weight, the coix seed of 9 parts by weight, the citron of 9 parts by weight, 15 parts by weight dragon
Eye meat, the donkey-hide gelatin of 9 parts by weight, the deer whip of 15 parts by weight, the Chinese cassia tree of 9 parts by weight, the matrimony vine of 12 parts by weight, 9 parts by weight cloves,
The raspberry of 15 parts by weight, the fennel of 6 parts by weight, the fructus amomi of 6 parts by weight, the Chinese yam of 9 parts by weight, the Radix Polygalae of 6 parts by weight, 6 weights
Measure the peach kernel of part, the earthworm of 9 parts by weight, the ginseng of 6 parts by weight, 12 parts by weight eucommia Bark male flower and 15 parts by weight oyster peptide.
4. a kind of preparation method of drug for promoting male's sexual and treating impotence, which is characterized in that including following step
Suddenly：
Step a：Weigh the Poria cocos of 3-18 parts by weight, the coix seed of 3-18 parts by weight, 3-18 parts by weight respectively in parts by weight
Citron, the arillus longan of 5-30 parts by weight, the donkey-hide gelatin of 3-18 parts by weight, the deer whip of 5-30 parts by weight, the Chinese cassia tree of 3-18 parts by weight, 12
The matrimony vine of parts by weight, the cloves of 3-18 parts by weight, the raspberry of 5-30 parts by weight, the fennel of 2-12 parts by weight, 2-12 parts by weight
Fructus amomi, the Chinese yam of 3-18 parts by weight, the Radix Polygalae of 2-12 parts by weight, the peach kernel of 2-12 parts by weight, the earthworm of 3-18 parts by weight, 2-
The oyster peptide of the ginseng of 12 parts by weight, the eucommia Bark male flower of 4-24 parts by weight and 5-30 parts by weight is as raw material for standby；
Step b：First respectively by donkey-hide gelatin, ginseng and deer whip drying and crushing to 120-200 targeted fine powders, then by Poria cocos, coix seed, perfume (or spice)
It is added in rafter, arillus longan, Chinese cassia tree, matrimony vine, cloves, raspberry, fennel, fructus amomi, Chinese yam, Radix Polygalae, peach kernel and eucommia Bark male flower mixing
After the water that 5-10 times of total weight is measured decocts twice respectively, the decocting liquid and filtration that merge twice obtain the first filtrate, at 80 DEG C -85 DEG C
Lower concentration first filtrate obtains the first clear cream, and ethyl alcohol is added into first clear cream makes the alcohol content of first clear cream
Reach 55%~80%, then ethyl alcohol is recycled after standing 24 hours, the second clear cream is concentrated to give at 50 DEG C -55 DEG C, then will be described
Second clear cream and ginseng, deer whip, donkey-hide gelatin, oyster peptide and the ground dragon protein fine powder mixing after crushing and drying, then it is crushed to 120-
After 200 targeted fine powders, pharmaceutically acceptable auxiliary material is added, pharmaceutically acceptable arbitrary dosage form is made.
5. the preparation method of the drug as claimed in claim 4 for promoting male's sexual and treating impotence, feature exist
In the described first time decocted was 1.5-2 hours, and described second time decocted is 0.5-1 hours.
6. the preparation method of the drug as claimed in claim 4 for promoting male's sexual and treating impotence, feature exist
In the relative density of first clear cream is 1.08-1.10.
7. the preparation method of the drug as claimed in claim 4 for promoting male's sexual and treating impotence, feature exist
In the relative density of second clear cream is 1.30-1.32.
8. the preparation method of the drug as claimed in claim 4 for promoting male's sexual and treating impotence, feature exist
In the pharmaceutically acceptable auxiliary material includes starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and its derivative
Object, gelatin, polyvinylpyrrolidone, glycerine, POLYSORBATE 80, agar, calcium carbonate, calcium bicarbonate, surfactant, gathers alginates
One or more of ethylene glycol, cyclodextrin, beta-cyclodextrin, phospholipid material, talcum powder, calcium stearate and magnesium stearate.
9. the preparation method of the drug as claimed in claim 4 for promoting male's sexual and treating impotence, feature exist
In the dosage form of the drug is tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule
Agent, oral solution, buccal tablet, granule, pill, powder, paste, sublimed preparation or ointment.
10. the preparation method of the drug as claimed in claim 9 for promoting male's sexual and treating impotence, feature exist
In the dosage form of the drug is tablet, capsule, oral solution, buccal tablet, granule, pill, powder, suspension, pulvis.More
Preferred Chinese medicine preparation is capsule, tablet, granule.
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| CN110651996A (en) * | 2018-08-01 | 2020-01-07 | 马晨光 | Food for nourishing and improving kidney function and preparation method thereof |
| CN110064020A (en) * | 2019-05-17 | 2019-07-30 | 商华 | A kind of male health-care formula and male health-care medicine |
| CN110721306A (en) * | 2019-11-28 | 2020-01-24 | 威海骄阳药业有限公司 | Composition for treating kidney deficiency |
| CN113768945A (en) * | 2021-08-12 | 2021-12-10 | 宁夏医科大学 | Application of geniposide in preparation of medicine for treating oligospermia |
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