CN109700887A - A kind of Chinese medicine composition and preparation method thereof for treating impotence and premature ejaculation - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating impotence and premature ejaculation Download PDFInfo
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- CN109700887A CN109700887A CN201910070631.3A CN201910070631A CN109700887A CN 109700887 A CN109700887 A CN 109700887A CN 201910070631 A CN201910070631 A CN 201910070631A CN 109700887 A CN109700887 A CN 109700887A
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Abstract
The invention discloses a kind of Chinese medicine compositions and preparation method thereof for treating impotence and premature ejaculation, belong to field of Chinese medicinal composition, and selecting Herba Epimedii, Morinda officinalis, Lu Bazi, Semen Cuscutae, fructus lycii, radix rehmanniae preparata, the root of three-nerved spicebush, testiset penis phocae, donkey kidney, mantis egg-case, teasel root, ten a herb material of hippocampus is raw material, with nourishing and strengthening Yin and Yang, strong kidney calming heart, tonifying primordial Qi, the effect of blood-nourishing production of sperm, cure mainly impotence, premature ejaculation, sexual function decline, and has and strengthen physique, antifatigue effect, pharmacological property mitigates, significant in efficacy.
Description
Technical field
The invention belongs to field of Chinese medicinal composition, and in particular to a kind of Chinese medicine composition for treating impotence and premature ejaculation and its preparation
Method.
Background technique
Impotence (ED), premature ejaculation (PE) are the common sex dysfunction diseases of adult male.With modern society's rhythm
Accelerate, study, life and the increase of operating pressure, and because of environmental pollution, the factors such as bad life style increases and lead to impotence,
The disease incidence and consultation rate of premature ejaculation improve year by year, since impotence is also known as " impotence ", and have discrimination derogatory sense, to patient with
Huge physiology and psychological pressure are come.
Currently, the pharmaceutical preparation for treating this kind of disease both at home and abroad be mostly add to the fun medea or influence NO metabolism blood vessel expand
Agent is opened, though interim use can help by force for the moment, vigour will be exhausted if being used for a long time, and damage human health.Also there are many Chinese patent drugs
Product occur, but these drugs still have following problems: firstly, most of this kind of medicine is all to take at that time effectively, drug withdrawal is
Without effect；In addition, existing drug must stimulate after taking in external cause just can use effect under subjective desire reinforcement.These drugs are deposited
In short-term effect, a period of time problem only can solve, cannot play the purpose of adjustment human endocrine and nervous system.Therefore, it opens
It is reliable to send out curative effect a kind of, and adverse reaction is few, and convenient for taking, the new drug for the treatment of both manifestation and root cause of disease is necessary.
Summary of the invention
It is an object of the invention to: a kind of Chinese medicine composition and preparation method thereof for treating impotence and premature ejaculation is provided, in solution
It is unreliable to state the existing curative effect of medication proposed in background technique, there is adverse reaction, inconvenience is taken, palliative problem.
The technical solution adopted by the invention is as follows:
A kind of Chinese medicine composition for treating impotence and premature ejaculation, the material medicine including following parts by weight: Herba Epimedii 95~105
Part, 95~105 parts of Morinda officinalis, 95~105 parts of Lu Bazi, 95~105 parts of Semen Cuscutae, 95~105 parts of fructus lycii, radix rehmanniae preparata 195~
205 parts, 95~105 parts of the root of three-nerved spicebush, 115~125 parts of testiset penis phocae, 20~30 parts of donkey kidney, 95~105 parts of mantis egg-case, teasel root 95~105
Part, 45~55 parts of hippocampus.
Further, a kind of Chinese medicine composition for treating impotence and premature ejaculation, the material medicine including following parts by weight: excessive sheep
100 parts of the leaves of pulse plants, 100 parts of Morinda officinalis, 100 parts of Lu Bazi, 100 parts of Semen Cuscutae, 100 parts of fructus lycii, 200 parts of radix rehmanniae preparata, 100 parts of the root of three-nerved spicebush,
120 parts of testiset penis phocae, 25 parts of donkey kidney, 100 parts of mantis egg-case, 100 parts of teasel root, 50 parts of hippocampus.
The Herba Epimedii acrid-sweet flavor that the present invention selects is warm-natured, walks liver kidney two warp, to mend the gate of vitality, strengthening the essence gas, strengthening the bones and muscles, Bu Shen Zhuang
The key medicine of sun；Morinda officinalis enters liver kidney two warp, there is the function of invigorating kidney yang tonifying primordial Qi；It is Lu Bazi bitter, warm-natured, enter kidney, Liver Channel, cures mainly cold
Hernia, abdomen coerce turgor, the disturbance of lower legs due to pathogenic cold and dampness, the kidney deficiency soreness of waist, impotence.Cold, cold and pain in the lower abdomen, herria, the disturbance of lower legs due to pathogenic cold and dampness for kidney void；Tu
Silk is sweet, warm, and kidney,liver,spleen is returned to pass through, and has the effect of nourishing liver and kidney, astringent sperm contracting urine, miscarriage prevention, improving eyesight, antidiarrheal, begins to carry " legendary god of farming's sheet
Grass warp ", be listed in top grade, sugariness generally has tonic effect, and sweet pungent tepor is reported gas and neutralized, not only can yang-tonifying, but also can benefiting yin, tool
Have it is warm but not dry, mend without stagnant feature；Fructus lycii is sweet in flavor, mild-natured, returns liver and kidney channel, has nourishing liver and kidney, the function of benefiting shrewd head
Effect；Radix rehmanniae preparata is sweet in flavor, slightly warm in nature, returns liver and kidney channel, has the effect of yin-nourishing of enriching blood, life essence-filling, marrow-benefitting；It is root of three-nerved spicebush acrid flavour, warm-natured, return lung,
Spleen, kidney, bladder meridian, have the effect of promoting qi circulation and relieving pain, warming kidney for dispelling cold；Testiset penis phocae is sweet in flavor, the big temperature of property, nontoxic, enters liver and kidney channel, has
There is establishing-Yang enriching yin, kidney-supplementing liver-boosting, adjust the effect of endocrine, enriching the blood and tonifying qi, beauty treatment skin makeup, powerful bone strengthening；Donkey kidney is sweet in flavor, salty,
It is warm-natured, there is the effect of kidney-reinforcing Yang-strengthening, strengthening the muscles and bones；Mantis egg-case taste is salty sweet, mild-natured, the effect of having astringent sperm contracting urine, tonify the kidney and support yang,
Weak compared with other animality Yang invigorating medicine effects, pharmacological property mitigates；Informal dress is without scorching disadvantage；Teasel root slightly warm in nature, it is bitter, pungent, return liver,
Kidney channel.There is nourishing liver and kidney, strengthening the bones and muscles, continuous injured, stop the effect of metrorrhagia and metrostaxis；Hippocampus have keep fit and healthy, tonifying kidney and strengthening yang, relaxing tendons and activating collaterals,
The medicinal functions such as anti-inflammatory analgetic, tranquilizing and allaying excitement, relieving cough and asthma.
A kind of preparation method of Chinese medicine composition that treating impotence and premature ejaculation, comprises the technical steps that:
(1) material medicine of following parts by weight is weighed respectively: 95~105 parts of Herba Epimedii, 95~105 parts of Morinda officinalis, reed
95~105 parts of Ba Zi, 95~105 parts of Semen Cuscutae, 95~105 parts of fructus lycii, 195~205 parts of radix rehmanniae preparata, 95~105 parts of the root of three-nerved spicebush, sea
115~125 parts of dog kidney, 20~30 parts of donkey kidney, 95~105 parts of mantis egg-case, 95~105 parts of teasel root, 45~55 parts of hippocampus, it is put into powder
Broken machine is broken into powder, sieves with 100 mesh sieve, and obtains powder-material；
(2) the powder-material extracting in water for obtaining step (1) twice, 10 times of water is added for the first time and decoct 2h, temperature 90
℃；Second of 6 times of water decoction 1h of addition into residue, temperature is 95 DEG C, and filtering merges decoction liquor twice；
(3) decoction liquor obtained in step (2) is concentrated, is concentrated into the medicinal extract that relative density is 1.5, then carries out
It dry, pulverize, sieve with 100 mesh sieve, obtain fine powder；
(4) required various customary adjuvants when fine powder addition obtained in step (3) being prepared different dosage forms, with routine
Method is prepared into any common peroral dosage form, i.e. Chinese medicine composition.
Further, the customary adjuvant be diluent, disintegrating agent, excipient, adhesive, lubricant, surfactant,
Filler, preservative, stabilizer, corrigent, thickener, one of cosolvent or a variety of.
Further, the common peroral dosage form be tablet, capsule, microcapsules, granule, pill, powder, take orally
Liquid, pill, sustained release preparation or controlled release preparation.
Parts by weight of the present invention be gram, two, jin, kilogram etc. unit of weights.
In conclusion by adopting the above-described technical solution, the beneficial effects of the present invention are:
1. the present invention select Herba Epimedii, Morinda officinalis, Lu Bazi, Semen Cuscutae, fructus lycii, radix rehmanniae preparata, the root of three-nerved spicebush, testiset penis phocae, donkey kidney,
Mantis egg-case, teasel root, ten a herb material of hippocampus are raw material, have nourishing and strengthening Yin and Yang, strong kidney calming heart, tonifying primordial Qi, the function of blood-nourishing production of sperm
Effect cures mainly impotence, premature ejaculation, sexual function decline, and has and strengthen physique, and antifatigue effect, pharmacological property mitigates, significant in efficacy, mark
Originally simultaneous to control.
2. medicinal extract obtained is crushed to 100 mesh during the preparation process by the present invention, effectively effective component can be made to be filled
The release and performance divided, promotes the absorption of each ingredient, and have no toxic side effect, securely and reliably.
3. preparation method of the invention is simple, technical maturity, raw material is natural, environmental-friendly, is suitble to large-scale production.
Specific embodiment
Complete clearly description is carried out to principles and features of the present invention combined with specific embodiments below, it is clear that described
Embodiment be only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ability
Domain those of ordinary skill every other embodiment obtained without making creative work, belongs to guarantor of the present invention
The range of shield.
Embodiment 1
A kind of preparation method of Chinese medicine composition that treating impotence and premature ejaculation, comprises the technical steps that:
(1) material medicine of following parts by weight: Herba Epimedii 95g, Morinda officinalis 95g, Lu Bazi 95g, Tu thread are weighed respectively
Sub- 95g, fructus lycii 95g, radix rehmanniae preparata 195g, root of three-nerved spicebush 95g, testiset penis phocae 115g, donkey kidney 20g, mantis egg-case 95g, teasel root 95g, hippocampus
45g is put into pulverizer and is broken into powder, sieve with 100 mesh sieve, obtains powder-material；
(2) the powder-material extracting in water for obtaining step (1) twice, 10 times of water is added for the first time and decoct 2h, temperature 90
℃；Second of 6 times of water decoction 1h of addition into residue, temperature is 95 DEG C, and filtering merges decoction liquor twice；
(3) decoction liquor obtained in step (2) is concentrated, is concentrated into the medicinal extract that relative density is 1.5, then carries out
It dry, pulverize, sieve with 100 mesh sieve, obtain fine powder；
(4) add appropriate amount of ethanol that particle is made fine powder obtained in step (3), dry, whole grain fills capsule, obtains finished product.
Instructions of taking: oral, one time 3 (0.6g crude drug/grain), 3 times a day, 15 days as one therapeutic course treats 2 treatments altogether
Journey；Duration of medication withdraws other related drugs and other treatments.
Embodiment 2
A kind of preparation method of Chinese medicine composition that treating impotence and premature ejaculation, comprises the technical steps that:
(1) material medicine of following parts by weight: Herba Epimedii 100g, Morinda officinalis 100g, Lu Bazi 100g, Tu are weighed respectively
Silk 100g, fructus lycii 100g, radix rehmanniae preparata 200g, root of three-nerved spicebush 100g, testiset penis phocae 120g, donkey kidney 25g, mantis egg-case 100g, teasel root 100g,
Hippocampus 50g is put into pulverizer and is broken into powder, sieve with 100 mesh sieve, obtains powder-material；
(2) the powder-material extracting in water for obtaining step (1) twice, 10 times of water is added for the first time and decoct 2h, temperature 90
℃；Second of 6 times of water decoction 1h of addition into residue, temperature is 95 DEG C, and filtering merges decoction liquor twice；
(3) decoction liquor obtained in step (2) is concentrated, is concentrated into the medicinal extract that relative density is 1.5, then carries out
It dry, pulverize, sieve with 100 mesh sieve, obtain fine powder；
(4) appropriate amount of starch slurry granulation is added in fine powder obtained in step (3), tabletting is made 400, obtains finished product.
Instructions of taking: it is oral, one time 8,2 times a day, 15 days as one therapeutic course treats 2 courses for the treatment of altogether；Duration of medication is withdrawn
Other related drugs and other treatments.
Embodiment 3
A kind of preparation method of Chinese medicine composition that treating impotence and premature ejaculation, comprises the technical steps that:
(1) material medicine of following parts by weight: Herba Epimedii 105g, Morinda officinalis 105g, Lu Bazi 105g, Tu are weighed respectively
Silk 105g, fructus lycii 105g, radix rehmanniae preparata 205g, root of three-nerved spicebush 105g, testiset penis phocae 125g, donkey kidney 30g, mantis egg-case 105g, teasel root 105g,
Hippocampus 55g is put into pulverizer and is broken into powder, sieve with 100 mesh sieve, obtains powder-material；
(2) the powder-material extracting in water for obtaining step (1) twice, 10 times of water is added for the first time and decoct 2h, temperature 90
℃；Second of 6 times of water decoction 1h of addition into residue, temperature is 95 DEG C, and filtering merges decoction liquor twice；
(3) decoction liquor obtained in step (2) is concentrated, is concentrated into the medicinal extract that relative density is 1.5, then carries out
It dry, pulverize, sieve with 100 mesh sieve, obtain fine powder；
(4) by the purified water softwood of fine powder obtained in step (3), general ball is made 400 balls, obtains finished product.
Instructions of taking: oral, 8 balls, 2 times a day, 15 days as one therapeutic course treats 2 courses for the treatment of altogether；Duration of medication is withdrawn
Other related drugs and other treatments.
Embodiment 4
It is as follows that the present invention treats 100 clinical reports of impotence and premature ejaculation:
1, above 100 patients are hospital outpatient clients, and max age 51 years old, minimal ages 27 years old, wherein 27-
30 years old 19,31-40 years old 38；41-50 years old 41,50 years old or more 2, the course of disease is most 2 months short, longest 8 years.Patient selection's mark
The first volume of formulation of quasi- basis " new Chinese medicine guideline of clinical investigations " (1993).Patient's main clinical manifestation is impotence, morning
It lets out, dizziness, tinnitus, amnesia, sleepy power, soreness and weakness of waist and knees.
2, diagnostic criteria: penis anorthosis or erection be not hard, cannot complete sexual intercourse person.
3, treatment method
All patients prepare capsule administration according to the formula in the embodiment of the present invention 1,3 tablets each time, 3 times a day, 15 days
It is as a treatment course, 2 courses for the treatment of are treated altogether；Duration of medication withdraws other related drugs and other treatments.
4, curative effect judging standard
According to " new Chinese medicine guideline of clinical investigations " (1993) first volume of formulation.
Cure: treatment 3 months, 90 ° of telotism >, the 75% of sexual intercourse chance can success；
Effective: 90 ° of erection > after treatment, the 50% of sexual intercourse chance can success；
Effective: erecing after treatment has improvement, and 25% or more of sexual intercourse chance can success；
In vain, medication front and back indices are without improvement.
5, result
Healing 58, effective 25, effective 6, invalid 11, total effective rate 89%.
Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art,
It is still possible to modify the technical solutions described in the foregoing embodiments, or part of technical characteristic is equal
Replacement, all within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in this hair
Within bright protection scope.
Claims (5)
1. a kind of Chinese medicine composition for treating impotence and premature ejaculation, which is characterized in that the material medicine including following parts by weight: excessive sheep
95~105 parts of the leaves of pulse plants, 95~105 parts of Morinda officinalis, 95~105 parts of Lu Bazi, 95~105 parts of Semen Cuscutae, 95~105 parts of fructus lycii,
195~205 parts of radix rehmanniae preparata, 95~105 parts of the root of three-nerved spicebush, 115~125 parts of testiset penis phocae, 20~30 parts of donkey kidney, 95~105 parts of mantis egg-case, continue
It is 95~105 parts, 45~55 parts of hippocampus disconnected.
2. a kind of Chinese medicine composition for treating impotence and premature ejaculation according to claim 1, which is characterized in that including following weight
The material medicine of number: 100 parts of Herba Epimedii, 100 parts of Morinda officinalis, 100 parts of Lu Bazi, 100 parts of Semen Cuscutae, 100 parts of fructus lycii, ripe
200 parts of ground, 100 parts of the root of three-nerved spicebush, 120 parts of testiset penis phocae, 25 parts of donkey kidney, 100 parts of mantis egg-case, 100 parts of teasel root, 50 parts of hippocampus.
3. a kind of preparation method for the Chinese medicine composition for treating impotence and premature ejaculation, which is characterized in that comprise the technical steps that:
(1) material medicine of following parts by weight is weighed respectively: 95~105 parts of Herba Epimedii, 95~105 parts of Morinda officinalis, Lu Bazi
95~105 parts, 95~105 parts of Semen Cuscutae, 95~105 parts of fructus lycii, 195~205 parts of radix rehmanniae preparata, 95~105 parts of the root of three-nerved spicebush, testiset penis phocae
115~125 parts, 20~30 parts of donkey kidney, 95~105 parts of mantis egg-case, 95~105 parts of teasel root, 45~55 parts of hippocampus, it is put into pulverizer
It is broken into powder, is sieved with 100 mesh sieve, powder-material is obtained；
(2) the powder-material extracting in water for obtaining step (1) twice, 10 times of water is added for the first time and decoct 2h, temperature is 90 DEG C；The
Secondary that 6 times of water decoction 1h are added into residue, temperature is 95 DEG C, and filtering merges decoction liquor twice；
(3) decoction liquor obtained in step (2) is concentrated, is concentrated into the medicinal extract that relative density is 1.5, is then done
It is dry, it crushes, sieves with 100 mesh sieve, obtain fine powder；
(4) required various customary adjuvants when fine powder addition obtained in step (3) being prepared different dosage forms, in conventional manner
It is prepared into any common peroral dosage form, i.e. Chinese medicine composition.
4. a kind of preparation method of Chinese medicine composition for treating impotence and premature ejaculation according to claim 3, which is characterized in that institute
Stating customary adjuvant is diluent, disintegrating agent, excipient, adhesive, lubricant, surfactant, filler, preservative, stabilization
Agent, corrigent, thickener, one of cosolvent or a variety of.
5. a kind of preparation method of Chinese medicine composition for treating impotence and premature ejaculation according to claim 3, which is characterized in that institute
State common peroral dosage form be tablet, capsule, microcapsules, granule, pill, powder, oral solution, pill, sustained release preparation or
Controlled release preparation.
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| CN110638894A (en) * | 2019-11-04 | 2020-01-03 | 邢乐 | Traditional Chinese medicine composition for treating impotence and premature ejaculation and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110638894A (en) * | 2019-11-04 | 2020-01-03 | 邢乐 | Traditional Chinese medicine composition for treating impotence and premature ejaculation and preparation method and application thereof |
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Application publication date: 20190503 |