CN107669930A - It is a kind of to be used to treat tabletting of gout and preparation method thereof - Google Patents

It is a kind of to be used to treat tabletting of gout and preparation method thereof Download PDF

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Publication number
CN107669930A
CN107669930A CN201711056030.4A CN201711056030A CN107669930A CN 107669930 A CN107669930 A CN 107669930A CN 201711056030 A CN201711056030 A CN 201711056030A CN 107669930 A CN107669930 A CN 107669930A
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parts
sealwort
pawpaw
root
tabletting
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CN201711056030.4A
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Chinese (zh)
Inventor
陈传朋
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Wuhan Herb Medicine Science And Technology Co Ltd
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Wuhan Herb Medicine Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of tabletting for being used to treat gout and preparation method thereof, it is related to field of medical technology, the tabletting includes following component by weight:25~30 parts of the root of kudzu vine, 15~20 parts of pawpaw, 20~30 parts of sealwort, 3~8 parts of lophatherum gracile, 5~10 parts of smilax, 6~12 parts of malt lake essence, 7~14 parts of microcrystalline cellulose, 4~11 parts of magnesium stearate, 3~8 parts of xylitol, 2~7 parts of Sucralose.The present invention can adjust hepatic and renal function, regulation and control uric acid balance, strengthen the blood circulation of each internal organs, enhance metabolism.The uric acid crystal of deposition is dissolved, blood circulation is rapidly entered, with renal metabolism.Da is to anti-trioxypurine, and cementing is brilliant, antipodagric final purpose.

Description

It is a kind of to be used to treat tabletting of gout and preparation method thereof
Technical field
It is specifically a kind of to be used to treat tabletting of gout and preparation method thereof the present invention relates to field of medical technology.
Background technology
Gout is red as caused by uric acid crystal stimulates region of interest, is swollen, play pain, necrosis, the world-famous puzzle disabled.Gout It is hepatic and renal function metabolic disorder, causes fast cry of certain animals metabolic disorder, uricacidemia is red to refer to disease, swells, heat, pain, and inflammatory reaction is clinic The dysbolism disease of performance.Its patient is numerous, and in rising trend.Domestic and international more rheumatism, are metabolized authoritative institution, Zeng Cai With various ways, produce a variety of:Analgesia, anti-inflammatory, all because curing the symptoms, not the disease, some even has stronger antiacid product to body Malicious wound is acted on and come to an end.
The content of the invention
For defect present in prior art, it is an object of the invention to provide a kind of tabletting for being used to treat gout and Its preparation method, hepatic and renal function can be adjusted, regulation and control uric acid balance, strengthens the blood circulation of each internal organs, enhances metabolism.Will The uric acid crystal dissolving of deposition, rapidly enters blood circulation, with renal metabolism.For Da to anti-trioxypurine, cementing is brilliant, antipodagric final Purpose.
To achieve the above objectives, the present invention adopts the technical scheme that:A kind of tabletting for being used to treat gout, including it is following Component by weight:25~30 parts of the root of kudzu vine, 15~20 parts of pawpaw, 20~30 parts of sealwort, 3~8 parts of lophatherum gracile, smilax 5 ~10 parts, 6~12 parts of malt lake essence, 7~14 parts of microcrystalline cellulose, 4~11 parts of magnesium stearate, 3~8 parts of xylitol, trichlorine sugarcane 2~7 parts of sugar.
The invention also discloses a kind of preparation method based on above-mentioned tabletting, comprise the following steps:Step S1. takes appropriate The root of kudzu vine, pawpaw, sealwort, lophatherum gracile and native Fu zero, respectively packing are cleaned standby;Step S2. by the clean root of kudzu vine, pawpaw, sealwort, Lophatherum gracile and native Fu zero, which load in drying baker, is dried;Step S3. is by the root of kudzu vine after drying, pawpaw, sealwort, lophatherum gracile and soil Fu small incidental expenses screen clothes are crushed;Step S4. takes appropriate malt lake essence, microcrystalline cellulose, magnesium stearate, xylitol and trichlorine multitudinous Sugar, mixed with the root of kudzu vine after crushing, pawpaw, sealwort, lophatherum gracile, native Fu zero, until uniform color;Step S5. will be mixed Then raw material dry-pressing afterwards is broken into particle into cake;Particle is added tabletting machine by step S6..
On the basis of above-mentioned technical proposal, in step S2, the temperature control in drying baker is at 80~120 DEG C.
On the basis of above-mentioned technical proposal, in step S3, the mesh number of screen cloth is 200 mesh.
The beneficial effects of the present invention are:
Product of the present invention can adjust hepatic and renal function, accelerate metabolism, anti-trioxypurine, cementing crystalline substance.Calmness is allowed in human body phase The crystallization differentiation dissolving at position is closed, by blood circulation by kidney excretion.Therapeutic effect can be reached in a short time:More it is not anti-after Bullet, the world history that gout is cured the symptoms, not the disease is reversed.This product is easily to cure gout in human body internal organs adjust rehabilitation.Fill out The another blank that traditional Chinese medicine cures gout is mended.
Embodiment
With reference to embodiment, the present invention is described in further detail, following examples be explanation of the invention and The invention is not limited in following examples.The present invention is defined to its addition, simply facilitates the implementation of the present invention, not Illustrate to implement outside limited range of the present invention.
The root of kudzu vine:Food and medicine consangunity, it is with a long history, it is tonic food suitable for people of all ages.Have《Ginseng in thousand》Good reputation.The root of kudzu vine Drop ' three is high ', protect liver kidney, improve blood circulation, strengthen renal blood flow amount, prevent uric acid from crystallizing in vivo, it is calm.
Sealwort:Ancient times are always kidney-tonifying and body-strengthening, the good merchantable brand promoted longevity.For deficiency of kidney essence.Soreness and weakness of waist and knees, enuresis nocturna frequency The diseases relevant with kidney such as number, fatigue and asthenia.Sealwort can make the renal function quick recovery of loss, and excretory function is vigorous.Height is allowed to urinate Acidaemia patient strangles gout pain in embryo.
Pawpaw:Relaxing tendons and activating collaterals, dissipate wind clearing damp, promoting blood circulation and stopping pain.For:Waist and knee joint, numbness resistance channels and collaterals, blood vessels are obstructed.It is pain Red, swollen, heat, the key medicine of pain dysfunction are alleviated or treated to wind.
Lily:Containing high potassium, help to strengthen muscle excitement levels, promote metabolic function to coordinate.Lily contains a kind of natural raw Thing alkali, uric acid in blood can be made quickly to reduce, crystallization-preventive is formed, and is mitigated and is protected hepatic and renal function to be damaged, with Da to anti-trioxypurine, cementing Crystalline substance, antipodagric final purpose.
Lophatherum gracile:It is clearing heat and detoxicating, only quench one's thirst, sharp stranguria with turbid discharge, clear mad phlegm.There is antibacterial, antitoxin, antitumor, anti-oxidation efficacy.For The formation of excretion or the crystallization of uric acid, there is obvious preventive and therapeutic effect.
The embodiments of the invention provide a kind of tabletting for being used to treat gout, including following component by weight:Pueraria lobota 25~30 parts of root, 15~20 parts of pawpaw, 20~30 parts of sealwort, 3~8 parts of lophatherum gracile, 5~10 parts of smilax, malt lake essence 6~12 Part, 7~14 parts of microcrystalline cellulose, 4~11 parts of magnesium stearate, 3~8 parts of xylitol, 2~7 parts of Sucralose.
Specifically, the tabletting can be made according to the component of following parts by weight meter:25 parts of the root of kudzu vine, 15 parts of pawpaw, sealwort 20 Part, 3 parts of lophatherum gracile, 5 parts of smilax, 6 parts of malt lake essence, 7 parts of microcrystalline cellulose, 4 parts of magnesium stearate, 3 parts of xylitol, trichlorine sugarcane 2 parts of sugar.
Specifically, the tabletting can be made according to the component of following parts by weight meter:30 parts of the root of kudzu vine, 20 parts of pawpaw, sealwort 30 Part, 8 parts of lophatherum gracile, 10 parts of smilax, 12 parts of malt lake essence, 14 parts of microcrystalline cellulose, 11 parts of magnesium stearate, 8 parts of xylitol, three 7 parts of chlorine sucrose.
This product can adjust hepatic and renal function, regulation and control uric acid balance, strengthen the blood circulation of each internal organs, promote new old generation Thank.The uric acid crystal of deposition is dissolved, blood circulation is rapidly entered, with renal metabolism.For Da to anti-trioxypurine, cementing is brilliant, controls gout Final purpose.
The embodiment of the present invention additionally provides a kind of preparation method for being used to treat the tabletting of gout, comprises the following steps:
Step S1. takes the appropriate root of kudzu vine, pawpaw, sealwort, lophatherum gracile and native Fu zero, and packing respectively is cleaned standby;This implementation 25 parts of the root of kudzu vine, 15 parts of pawpaw, 20 parts of sealwort, 3 parts of lophatherum gracile, 5 parts of smilax are chosen in example.
Step S2., which loads the clean root of kudzu vine, pawpaw, sealwort, lophatherum gracile and native Fu zero in drying baker, is dried;Specifically , in step S2, the temperature control in drying baker is at 80~120 DEG C.
Step S3. is crushed the root of kudzu vine after drying, pawpaw, sealwort, lophatherum gracile and native Fu small incidental expenses screen cloth;Specifically, In step S3, the mesh number of screen cloth is 200 mesh.
Step S4. takes appropriate malt lake essence, microcrystalline cellulose, magnesium stearate, xylitol and the multitudinous sugar of trichlorine, after crushing The root of kudzu vine, pawpaw, sealwort, lophatherum gracile, native Fu zero mixed, until uniform color;Malt lake essence 6 is chosen in the present embodiment Part, 7 parts of microcrystalline cellulose, 4 parts of magnesium stearate, 3 parts of xylitol, 2 parts of Sucralose.
Mixed raw material dry-pressing into cake, is then broken into particle by step S5.;
Particle is added tabletting machine by step S6.《Fast acid is clear》Tabletting.Several, bottling, spiral cover heat-sealing, labeling, External packing box stamp, dispatches from the factory.
Practical case:
So-and-so is shut out, 56 years old, Xiamen of Fujian Province people.Suffer from tophus 16 years as long as, two hands and the multiple arthroceles of both feet form pain Wind stone, maintain symptom by anodyne and hormone for many years.Life can not take care of oneself at present, feel restless, repeatedly expect committing suiside.2016 July in year starts to take《Fast acid is clear》October, red and swollen disappearance, can normally walk, life can take care of oneself.
Leaf so-and-so, 40 years old, Hubei people from Gongan County, be engaged in marketing work.Suffer from urarthritis more than 5 years, it is red whenever breaking out It is swollen obvious, cut-like pain, difficulty in walking.Uric acid level 696.Transfusion bottle is hung when initial stage breaks out to be alleviated, to have hung the latter moon 6 times It is ineffective.In May, 2017 starts to take《Fast acid is clear》Have urine examined acid after more than 20 days, and uric acid level is down to 372, drops travel time mistake now The long or change of weather, former damaged joints have slight discomfort outer, again have no red and swollen phenomenon.
Yang, 22 years old, Kunming, Yunnan people.Start podarthrum in June, 2014 and be alternately present red, swollen, pain.Break out every time all It need to hang 4 days or so and hang water and could mitigate, can hardly go to work.Laboratory examination:Uric acid level 684, B ultrasound are found:Hepatic duct and double The multiple calculus of side urinary system (caused by uric acid crystal).Seek medical advice, have no idea everywhere.In April, 2017 starts to take《Fast acid is clear》, ten Five Tian Houqu hospitals check:Uric acid level 440, B ultrasound calculus have also lacked many.
The present invention is not limited to the above-described embodiments, for those skilled in the art, is not departing from On the premise of the principle of the invention, some improvements and modifications can also be made, these improvements and modifications are also considered as the protection of the present invention Within the scope of.The content not being described in detail in this specification belongs to prior art known to professional and technical personnel in the field.

Claims (4)

1. a kind of tabletting for being used to treat gout, it is characterised in that including following component by weight:The root of kudzu vine 25~30 Part, 15~20 parts of pawpaw, 20~30 parts of sealwort, 3~8 parts of lophatherum gracile, 5~10 parts of smilax, 6~12 parts of malt lake essence, crystallite 7~14 parts of cellulose, 4~11 parts of magnesium stearate, 3~8 parts of xylitol, 2~7 parts of Sucralose.
2. the preparation method based on tabletting described in claim 1, it is characterised in that comprise the following steps:
Step S1. takes the appropriate root of kudzu vine, pawpaw, sealwort, lophatherum gracile and native Fu zero, and packing respectively is cleaned standby;
Step S2., which loads the clean root of kudzu vine, pawpaw, sealwort, lophatherum gracile and native Fu zero in drying baker, is dried;
Step S3. is crushed the root of kudzu vine after drying, pawpaw, sealwort, lophatherum gracile and native Fu small incidental expenses screen cloth;
Step S4. takes appropriate malt lake essence, microcrystalline cellulose, magnesium stearate, xylitol and the multitudinous sugar of trichlorine, with the Pueraria lobota after crushing Root, pawpaw, sealwort, lophatherum gracile, native Fu zero are mixed, until uniform color;
Mixed raw material dry-pressing into cake, is then broken into particle by step S5.;
Particle is added tabletting machine by step S6..
3. preparation method as claimed in claim 2, it is characterised in that:In step S2, temperature control in drying baker 80~ 120℃。
4. preparation method as claimed in claim 2, it is characterised in that:In step S3, the mesh number of screen cloth is 200 mesh.
CN201711056030.4A 2017-11-01 2017-11-01 It is a kind of to be used to treat tabletting of gout and preparation method thereof Pending CN107669930A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111991530A (en) * 2020-09-21 2020-11-27 广西谢郡堂科技股份有限公司 Medicine for treating gout and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
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Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107223961A (en) * 2016-03-25 2017-10-03 珠海宝德润生健康科技有限公司 A kind of composition with effects of relieving alcoholism and protecting liver and preparation method thereof

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111991530A (en) * 2020-09-21 2020-11-27 广西谢郡堂科技股份有限公司 Medicine for treating gout and preparation method thereof

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