CN106138167A - A kind of Chinese medicine composition treating thrombotic disease - Google Patents
A kind of Chinese medicine composition treating thrombotic disease Download PDFInfo
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Abstract
The present invention has separated a kind of Chinese medicine composition treating thrombotic disease, and it is formulated by the raw material of Chinese medicine of following weight, Herba Ephedrae 18000, Concha Arcae 13000, Radix seu Folium Gaultheriae Forrestii 15000, Herba Portulacae 15000, Caulis Gneti Parvifolii 14500, natural Moschus 30.Advantages of the present invention, thrombus is rapid soon, thoroughly, effect outstanding feature.Treatment thrombosis effect: effective percentage 98%, cure rate 80%.
Description
Technical field
The invention belongs to pure technical field of Chinese medicines, a kind of Chinese medicine composition treating thrombotic disease.
Background technology
Thrombosis is the fritter that blood flow is formed on the surface of cardio-cerebrovascular blood vessel inner face exfoliation or mend.Thrombosis
The platelet deposited by insoluble fibrin, the leukocyte of accumulation and the erythrocyte composition being absorbed in.Traditional medicine thinks thrombosis
Being to be caused stagnation of QI blood stagnation by many factors, blood stagnation forms blood and fastens in Ink vessel transfusing.At present, the apoplexy caused due to thrombosis,
Cerebral thrombosis, heart thromboembolism, limbs phlebothrombosis, the patient of lung thrombosis steeply rise, and bring greatly pressure to the economic life of people
Power.Modern medicine is mainly with thrombolytic drug, antiplatelet drug and anticoagulant therapy thrombosis.Such as: the medicine such as streptokinase, heparin
Thing.Traditional Chinese Medicine mainly with blood circulation promoting and blood stasis dispelling, the Chinese medicine thrombus of the meridian dredging, such as: XUESHUANTONG JIAONANG " Zhenbao Island, Heilongjiang Province
Pharmaceutical limited company ", the medicine such as Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Radix Notoginseng, Hirudo, Moschus, Flos Carthami, Rhizoma Sparganii, Rhizoma Curcumae, Pheretima, it treats blood
Bolt disease effect is the most undesirable.
Summary of the invention
The purpose of the present invention is that a kind of pure Chinese medicinal preparation treating thrombotic disease of offer, and it is fast that it has treatment thrombus
Speed, thoroughly, effect outstanding feature.
The technical scheme is that and be achieved in that, a kind of Chinese medicine composition treating thrombotic disease, it is characterised in that: it
It is formulated by the raw material of Chinese medicine of following weight, Herba Ephedrae 18000, Concha Arcae 13000, Radix seu Folium Gaultheriae Forrestii 15000, Herba Portulacae
15000, Caulis Gneti Parvifolii 14500, natural Moschus 30.First Moschus is ground impalpable powder standby.Then above raw material of Chinese medicine is put
Entering in marmite, in marmite, to cross powder high 5 centimetres for pouring, soaks and water was outwelled in 20 minutes, and in marmite, pouring crosses medicine the most again
Face is high 5 centimetres, then covering marmite lid, endures out with high heat, then uses slow fire instead and endures 30 minutes medicinal liquid is poured out；Again in marmite
It is high 5 centimetres that pouring crosses powder, covers marmite lid, endures out with high heat, then uses slow fire instead and endures 30 minutes medicinal liquid is poured out；Again to sand
It is high 5 centimetres that the interior pouring of pot crosses powder, covers marmite lid, endures out with high heat, then endures 30 minutes with slow fire and then medicinal liquid is poured out；
Again in marmite pouring to cross powder high 5 centimetres, cover marmite lid, endure out with high heat, then endure 30 minutes then medicine with slow fire
Liquid is poured out.Then marmite poured into by the medicinal liquid one piece the 1st time, the 2nd time, the 3rd time, the 4th time endured, and covers marmite lid, endures with high heat
Open, then use instead slow fire endure to become ointment time, pour out and dry in the shade or be placed on drying in oven, the temperature of baking oven between 45-55 DEG C,
Then the ointment done was pulverized 300 mesh sieves, then by Moschus powder and medicated powder mix homogeneously, gained medicated powder was received bottle standby.
" weight " of described raw material of Chinese medicine is as unit with " gram ".
Treat the course for the treatment of: within 15 days, being a course for the treatment of, the lighter can cure 1 course for the treatment of, and severe one 2-5 can be cured the course for the treatment of.
Instructions of taking and dose: take 3 day, early, the noon, after supper under warm water clothes.Each serving 3 grams.
Therapeutic effect: effective percentage 98%, cure rate 80%.
Medicine of the present invention has thrombolytic effect.
Medicine of the present invention is applicable to apoplexy, cerebral thrombosis, heart thromboembolism, limbs phlebothrombosis, lung thrombosis, cardinal symptom: half side
Paralysis of the limbs, slurred speech, mind are still clear, uncomfortable in chest, angina pectoris, feel suffocated, and rear backache is panted, uncomfortable in chest, breathes hard, chest pain, low grade fever,
Hemoptysis.
The drug action mechanism of the present invention is as follows:
Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature.Gui Jing.Return lung, bladder warp.There is diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema
Effect.It is used for chill exterior syndrome, uncomfortable in chest breathes with cough, edema due to wind pathogen edema, rheumatic arthralgia, carbuncle of yin nature, sucutaneous nodule.
Radix seu Folium Gaultheriae Forrestii: sweet in the mouth, pungent, cold nature.Gas is fragrant.There is blood circulation promoting and blood stasis dispelling, granulation promoting synthetism, relieving stranguria by diuresis, dampness removing jaundice eliminating, dispel
Effect of phlegm and relieving cough.For replantation of amputated finger, traumatic injury, fracture, dispel the wind, dehumidifying, rheumatism paralysis, menoxenia, menstrual pain, yellow
Subcutaneous ulcer, cholelithiasis, exogenous cough, chilblain.
Herba Portulacae: sour in the mouth.Cold nature.There is heat-clearing and toxic substances removing, subduing inflammation, hemostasis, effect of diuretic damp eliminating.It is mainly used to dysentery
Disease, enteritis, nephritis, the diseases such as puerperal, metrorrhagia, had blood in stool, mastitis, lung abscess, ulcerative carbuncle.
Caulis Gneti Parvifolii: bitter in the mouth, slightly warm in nature.There is wind-damp dispelling, blood circulation promoting and blood stasis dispelling, hemostasis, effect of expelling phlegm for arresting cough.For wind
Wet arthritis, lumbar muscle strain, soreness of bones and muscles, traumatic injury, bronchitis, ulcerative hemorrhage, venom, fracture is controlled in external.
Natural Moschus: acrid in the mouth.Warm in nature.GUIXIN, lung meridian.There is fragrant inducing resuscitation, promoting blood circulation to remove blood stasis, the effect of lower tire of hastening parturition.With
Heat-blockage coma, convulsion in heat attacking the pericardium are fainted, apoplexy syncope due to accumulation of phlegm, attacked by pestiferous factors pathogen, ulcerative carbuncle toxic swelling, amenorrhea, injury from falling down abdominal mass.
Concha Arcae: sweet in the mouth, salty, property is put down.Return lung, stomach, liver, spleen channel.There is expectorant of invigorating blood circulation, effect of relieving gastric hyperacidity to alleviate stomachache.For
Abdominal mass mass in the abdomen.
Above drug reference: (TCM Recipe pharmacy, the Guangdong college of traditional Chinese medicine compiles, the Guangdong People's Press, June in 1973 the 1st edition
1st printing)
Natural Moschus's fragrance inducing resuscitation in side, promoting blood circulation to remove blood stasis, Herba Ephedrae diaphoresis cold expelling, inducing diuresis to remove edema share have for monarch the most molten
Solve the effect of thrombosis；With Concha Arcae, Herba Portulacae, Caulis Gneti Parvifolii blood circulation promoting and blood stasis dispelling, expectorant hemostasis, diuretic damp eliminating is that minister dissolves blood
Bolt, strengthens Moschus, the thrombolytic effect of Herba Ephedrae；It is that assistant makes the through sick institute of priming power with Radix seu Folium Gaultheriae Forrestii, with rapid thrombus, reaches
To eliminating rapidly half side paralysis of the limbs, slurred speech, mind are still clear, uncomfortable in chest, angina pectoris, feel suffocated, and rear backache is panted, uncomfortable in chest, gas
Short, chest pain, low grade fever, all diseases such as hemoptysis, cure thrombotic disease apoplexy, cerebral thrombosis, heart thromboembolism, limbs phlebothrombosis, the effect of lung thrombosis
Really.
Traditional medicine thinks that thrombosis is to be caused stagnation of QI blood stagnation by many factors, and blood stagnation forms blood and fastens in Ink vessel transfusing.Due to
The formation of thrombosis, the apoplexy caused, cerebral thrombosis, heart thromboembolism, limbs phlebothrombosis, lung thrombosis bring to the economic life of people
Enormous pressure, treatment thrombotic disease should be with thrombus for wanting, and thromboembolism, vascular flow is unobstructed, the most half side paralysis of the limbs, speech
All diseases such as unclear, mind is still clear, uncomfortable in chest, angina pectoris, feels suffocated, and rear backache is panted, uncomfortable in chest, breathes hard, chest pain, low grade fever, hemoptysis from
Good, then apoplexy, cerebral thrombosis, heart thromboembolism, limbs phlebothrombosis, lung thrombosis are regarded for oneself.
Specific embodiments
Below in conjunction with embodiment, the present invention can be further illustrated.
Embodiment: take Herba Ephedrae 18000, Concha Arcae 13000, Radix seu Folium Gaultheriae Forrestii 15000, Herba Portulacae 15000, Caulis Gneti Parvifolii
14500, natural Moschus 30.First Moschus is ground impalpable powder standby.Above raw material of Chinese medicine is put in marmite, falls in marmite
It is high 5 centimetres that water crosses powder, soaks and water was outwelled in 20 minutes, the most again in marmite pouring to cross powder high 5 centimetres, then covering sand
Pot cover, endures out with high heat, then uses slow fire instead and endures 30 minutes medicinal liquid is poured out；Again in marmite pouring to cross powder high 5 centimetres, lid
Upper marmite lid, endures out with high heat, then uses slow fire instead and endures 30 minutes medicinal liquid is poured out；Again in marmite pouring to cross powder high 5 lis
Rice, covers marmite lid, endures out with high heat, then endure 30 minutes with slow fire and then medicinal liquid is poured out；In marmite, pouring crosses medicine again
Face is high 5 centimetres, covers marmite lid, endures out with high heat, then endures 30 minutes with slow fire and then medicinal liquid is poured out.Then the 1st time,
Marmite poured into by the medicinal liquid one piece that 2nd time, the 3rd time, the 4th time is endured, and covers marmite lid, endures out with high heat, then use instead slow fire endure to
Become ointment time, pour out and dry in the shade or be placed on drying in oven, the temperature of baking oven between 45-55 DEG C, the ointment powder then will done
Broken mistake 300 mesh sieve, then by Moschus powder and medicated powder mix homogeneously, receives bottle by gained medicated powder standby.
" weight " of described raw material of Chinese medicine is as unit with " gram ".
Treat the course for the treatment of: within 15 days, being a course for the treatment of, the lighter can cure 1 course for the treatment of, and severe one 2-5 can be cured the course for the treatment of.
Instructions about how to take medicine and dose: take day 3 times, each serving 3 grams, early, the noon, after supper under warm water clothes.
Therapeutic effect: effective percentage 98%, cure rate 80%.
Medicine of the present invention has thrombolytic effect.
Medicine of the present invention is applicable to apoplexy, cerebral thrombosis, heart thromboembolism, limbs phlebothrombosis, lung thrombosis.
Medicine of the present invention is applicable to apoplexy, cerebral thrombosis, heart thromboembolism, limbs phlebothrombosis, lung thrombosis, cardinal symptom: half side
Paralysis of the limbs, slurred speech, mind are still clear, uncomfortable in chest, angina pectoris, feel suffocated, and rear backache is panted, uncomfortable in chest, breathes hard, chest pain, low grade fever,
Hemoptysis.
One, it is the effect showing medicine of the present invention, in vitro test: the finger blood taking 50 people respectively drips 50 into sterilizing
In individual teat glass, in each test tube, everyone is respectively dropped into blood 1, drips 50 teat glasses altogether, after blood solidification in bulk,
Then separating tests group and matched group, often organizes and averagely gives 25 teat glasses instilling blood 1.Test group gives 25 instillations
Blood 1 bleed solidification in bulk teat glass, matched group give 25 instill blood 1 bleed solidification in bulk teat glass.
Illustrate: instill blood 1 and bleed the temperature of teat glass of solidification in bulk at 36-37 DEG C.
1, test group medicine of the present invention, the teat glass Nei Saben of solidification in bulk of bleeding to 25 instillation blood 1 respectively
0.3 gram of medicated powder of invention medicine, 6h shaking test tube is once, it was observed that clot has dissolved 1/3rd；The present invention is added again in test tube
0.3 gram of medicated powder of medicine, after 6h, shaking test tube once, observes that again clot has dissolved 1/2nd again；Again to test tube Nei Jiabenfa
0.3 gram of medicated powder of bright medicine, after 6h, shaking test tube once, observes that again clot has dissolved 2/3rds again；Again to test tube Nei Jiaben
0.3 gram of medicated powder of invention medicine, after 6h, shaking test tube once, observes that again clot has been completely dissolved as blood and slime again.
2, matched group is respectively by streptokinase, XUESHUANTONG JIAONANG " Zhenbao Island, Heilongjiang Province Pharmaceutical limited company ", difference
To 25 instill blood 1 bleed solidification in bulk teat glass in spread pesticides powder.
A, with streptokinase to 10 instill blood 1 bleed solidification in bulk teat glass in spread streptokinase medicated powder 20u, every 6h
Shaking test tube is once, it was observed that clot is undissolved；Spreading streptokinase medicated powder 10u again in test tube, after 6h, shaking test tube once, is seen again
Observe clot the same；Spreading streptokinase medicated powder 10u again in test tube, after 6h, shaking test tube is once again, it was observed that clot has dissolved ten
/ mono-；Spreading streptokinase medicated powder 10u again in test tube, after 6h, shaking test tube is once again, it was observed that clot has dissolved 2/10ths.
B, with XUESHUANTONG JIAONANG to 15 instill blood 1 bleed solidification in bulk each test tube of teat glass in spread XUESHUANTONG
1, capsule medicated powder, every 6h shaking test tube is once, it was observed that clot is undissolved；1, XUESHUANTONG JIAONANG medicated powder is spread again in test tube,
After 6h, shaking test tube is once again, it was observed that clot has slight dissolving；Spread 1, XUESHUANTONG JIAONANG medicated powder again, in test tube after 6h again
Shaking test tube is once, it was observed that clot has a small amount of dissolving；1, XUESHUANTONG JIAONANG medicated powder in test tube again, shaking test tube again after 6h
Once, it was observed that clot has dissolved 2/10ths.
Two, the clinical observation of Drug therapy cerebral thrombosis of the present invention:
1, inclusive criteria
Taking 50 example cerebral thrombus patients, cardinal symptom: half side paralysis of the limbs, slurred speech, mind are still clear, and the age is at 35-65
In year, morbidity is about 3 months or half a year.Above patient is all diagnosed as cerebral thrombosis with CT.
2, treatment evaluation criteria
Effective: half side paralysis of the limbs, the most clear all diseases of slurred speech, mind alleviate, and the state of an illness can be stable.
Recovery from illness: half side paralysis of the limbs, the most clear all diseases of slurred speech, mind are wholly absent.
3, Therapeutic Method
Take medicine of the present invention, take day 3 times, each serving 3 grams, early, the noon, warm boiled water after supper.
4, the treatment course for the treatment of
Within 15 days, it is 1 course for the treatment of, treats 3 courses for the treatment of.
5, therapeutic outcome
Through with the above-mentioned cerebral thrombus patient of Drug therapy of the present invention, through 3 courses for the treatment of of treatment, effective 49 examples, 40 examples of fully recovering, effectively
Rate 98%, cure rate 80%.
Three, by XUESHUANTONG JIAONANG, streptokinase treatment cerebral thrombosis clinical observation.
1, inclusive criteria
Taking 50 example cerebral thrombus patients, cardinal symptom: half side paralysis of the limbs, slurred speech, mind are still clear, and the age is at 35-65
In year, morbidity is about 3 months or half a year.Above patient is all diagnosed as cerebral thrombosis with CT.
2, treatment evaluation criteria
Effective: half side paralysis of the limbs, the most clear all diseases of slurred speech, mind alleviate, and the state of an illness can be stable.
Recovery from illness: half side paralysis of the limbs, the most clear all diseases of slurred speech, mind are wholly absent.
3, Therapeutic Method
First, first, day intravenous drip streptokinase 50u, second day intravenous drip streptokinase 60u, continuous intravenous infusion chain
Kinases 6 days, stopping streptokinase, after, each serving XUESHUANTONG JIAONANG 1, three times a day, early, the noon, warm water clothes after supper
Under.
4, the treatment course for the treatment of
Within 15 days, it is 1 course for the treatment of, treats 3 courses for the treatment of.
5, therapeutic outcome
Through by XUESHUANTONG JIAONANG, streptokinase treats above-mentioned cerebral thrombus patient, and effective 26,12 examples of fully recovering, effective percentage 52%, fully recover from an illness
More rate 24%.
Through above clinical treatment observation, take the effect of Drug therapy cerebral thrombosis of the present invention and be substantially better than and use XUESHUANTONG glue
Capsule, the effect of streptokinase treatment cerebral thrombosis.
Model case: Ma Lou township, Taiqian County Miao Kou, an XX, man, 54 years old, on March 5th, 2011 examined, and disease is seen: mouth eye is to the left
Crooked, aphasia, left lower limb activity is unfavorable, numb, it is impossible to walk, left hand fiber crops, it is impossible to by thing, physique still can, have a meal can, greatly
Urine is unchanged, and half a year of falling ill is many, and clinical diagnosis is cerebral thrombosis.Once remove the large hospital such as Liaocheng, Jinan, eat Chinese and Western
Medicine, does not feels any better, and tells it and withdraws all medicines, takes medicine of the present invention with changing, by taken three times per day, early, the noon, evening one after each meal, every time
Taking 6 grams, with warm boiled water, by the medicine of 15 days, examine again after taking medicine of the present invention 15 days, left hand is the numbest, and left lower limb can
Land on foot, the most askew light of mouth eye, can speak, tell it and take the medicine of 30, still by taken three times per day, one after each meal again, every time
Take 3 grams, use warm boiled water.Three examine, all transference cures, for consolidating curative effect, tell its medicine of the present invention taken again 30 days, press
Within 1st, take 1 time, each serving 3 grams, taking medicine after meal, warm boiled water, follow up a case by regular visits to not recur so far.
East Street, Shouzhang town, Yanggu County, fourth XX, female, 58 years old, go to a doctor on July 11st, 2012, symptom: pain uncomfortable in chest, left shoulder
Pain in inside the back of the body, in paroxysmal pain, angina pectoris, blood pressure: low pressure 115 mercury column, high pressure 170 mercury column, through by CT examination, display
Coronary artery has thrombosis, and clinical diagnosis is coronary heart disease.Tell it and withdraw all medicines, change and take medicine of the present invention, allow it take the present invention
The medicine medicine of 15 days, examines again after taking 15 days by drug use method of the present invention, and breast is the most vexed, and other all disease changes the most
Kind, to tell its medicine of the present invention taken again 30 days, still take by drug use method of the present invention, examine again after 30 days, all symptoms are complete
Complete disappear, for consolidating curative effect, then medication 30 days, change into taking medicine every day 1 time, each serving 3 grams, follow up a case by regular visits to not recur so far.
Claims (1)
1. the Chinese medicine composition treating thrombotic disease, it is characterised in that: it is formulated by the raw material of Chinese medicine of following weight
, Herba Ephedrae 18000, Concha Arcae 13000, Radix seu Folium Gaultheriae Forrestii 15000, Herba Portulacae 15000, Caulis Gneti Parvifolii 14500, natural Moschus 30.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108478660A (en) * | 2018-05-30 | 2018-09-04 | 河南金凤生物科技有限公司 | A kind of Chinese medicine preparation and preparation method thereof for treating blood vessel blockage |
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| CN1199641A (en) * | 1998-06-26 | 1998-11-25 | 张阳 | Chinese medicine preparation for preventing and curing cerebral thrombus |
| CN101357198A (en) * | 2008-09-12 | 2009-02-04 | 康兆毅 | Traditional Chinese medicine for treating cerebral thrombus |
| CN103638156A (en) * | 2013-11-26 | 2014-03-19 | 宋爱民 | Traditional Chinese medicine preparation for treating blood stasis angiitis |
| CN104474339A (en) * | 2014-12-10 | 2015-04-01 | 云南省第二人民医院 | Traditional Chinese medicine for treating thrombus and preparation method of traditional Chinese medicine |
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2016
- 2016-07-13 CN CN201610595765.3A patent/CN106138167A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1199641A (en) * | 1998-06-26 | 1998-11-25 | 张阳 | Chinese medicine preparation for preventing and curing cerebral thrombus |
| CN101357198A (en) * | 2008-09-12 | 2009-02-04 | 康兆毅 | Traditional Chinese medicine for treating cerebral thrombus |
| CN103638156A (en) * | 2013-11-26 | 2014-03-19 | 宋爱民 | Traditional Chinese medicine preparation for treating blood stasis angiitis |
| CN104474339A (en) * | 2014-12-10 | 2015-04-01 | 云南省第二人民医院 | Traditional Chinese medicine for treating thrombus and preparation method of traditional Chinese medicine |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108478660A (en) * | 2018-05-30 | 2018-09-04 | 河南金凤生物科技有限公司 | A kind of Chinese medicine preparation and preparation method thereof for treating blood vessel blockage |
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Address after: 252000 Room 202, unit 4, 1 building, 68 Dongchang West Road, Liaocheng, Shandong. Applicant after: Jiang Baozhen Address before: 253000 Yanggu county science and Technology Bureau, Shandong Province Applicant before: Jiang Baozhen |
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Application publication date: 20161123 |
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