CN100349608C - Obstruction dredging medicine pill and its prepn - Google Patents

Obstruction dredging medicine pill and its prepn Download PDF

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CN100349608C
CN100349608C CNB2005100127802A CN200510012780A CN100349608C CN 100349608 C CN100349608 C CN 100349608C CN B2005100127802 A CNB2005100127802 A CN B2005100127802A CN 200510012780 A CN200510012780 A CN 200510012780A CN 100349608 C CN100349608 C CN 100349608C
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pill
dry
rhizoma atractylodis
prepared
treatment
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CN1739621A (en
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程玉峰
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Abstract

The present invention discloses a Chinese medicine-obstruction dredging medicine pill and a preparation method thereof, which is characterized in that the obstruction dredging medicine pill is prepared from raw medicines of 10g of pyrola herb concentrated powder, 10g of wuxing prepared atractylodes rhizome, 10g of cyathula root, 10g of raw frankincense, 10g of raw myrrh, 10g of scorpion, 10g of silkworm larva, 10g of long-noded pit viper, 20g of turtle pearl, 200g of prepared nuxvomica, etc. The preparation method comprises the steps of preparing the pyrola herb concentrated powder and the wuxing prepared atractylodes rhizome, and conventionally preparing honeyed bolus according to the formula. The obstruction dredging medicine pill has the efficiencies of activating blood circulation to dissipate blood stasis, activating meridians to stop pain, tonifying the liver and kidney, strengthening tendons and bones, expelling wind, clearing away cold, removing humidity, eliminating swelling, circulating blood in bones, benefiting joints and recovering bodies. The present invention is suitable for treating various kinds of arthrosi, such as rheumatic arteritis, rheumatoid arthritis, cervical syndrome, lumbar intervertebral disc protrusion, lumbar muscle strain, sciatica, periarthritis of shoulder, hyperosteogeny, etc.

Description

Be used for the treatment of pill of various disorder of joint and preparation method thereof
Technical field: the invention belongs to Chinese patent drug technique field, relate to a kind of pill that is used for the treatment of various disorder of joint and preparation method thereof specifically.
Background technology: disorder of joint a multitude of names such as rheumatic, rheumatoid arthritis, cervical vertebra pain, prolapse of lumbar intervertebral disc, lumbar muscle strain, sciatica, scapulohumeral periarthritis, hyperosteogeny or the like, is a kind of common and disease of being difficult to effect a radical cure.Motherland's medical science thinks that the pathogenic factor of this class disease mostly is the endogenous cause of ill deficiency of the liver and kindey, affection of exogenous wind-cold, wet, hot, thus cause caused by energy stagnation and blood stasis.Clinical symptoms mostly is neck, shoulder, waist, the pain that has a pain in the leg, and the whole body is numb, and muscle, joint, muscles and bones are ached, joint stuffiness, limitation of activity etc.The traditional Chinese medical science to be adopted and consolidates the promote blood circulation Therapeutic Principle of network of cold expelling, expelling wind and removing dampness, a surname.Usually adopt Chinese medicinal formulae such as Chinese medicine decoction, DAHUOLUO WAN, anti-hyperosteogeny pill, JINGFUKANG, YAOTONGNING and Chinese patent medicine etc.And the new drug for the treatment of this class disease at present also has some these class new techniques open still in continuous release in the Chinese patent.Yet, still having all Polyarthropathy obstinates in the actual life, clinical hospitalier's course of disease is very few with interior person at 3 months, and many patients are agonizing.This explanation, existing medicine still can not be satisfied these type of treatment of conditions needs fully, and motherland's medical treasure-house awaits further excavation, and the better new drug of clinical needs comes out, to remove the hardship of more slight illness.
Summary of the invention: the objective of the invention is,, provide a kind of pill of various disorder of joint and preparation method thereof that is used for the treatment of evident in efficacy at clinical needs.Its technical solution is:
A kind of pill that is used for the treatment of various disorder of joint, it is characterized in that it is made by following raw materials by weight proportions: Herba Pyrolae concentrated dry powder 10g, Rhizoma Atractylodis 10g, Radix Cyathulae 10g, Olibanum 10g, Myrrha 10g, Scorpio 10g, Bombyx Batryticatus 10g, Agkistrodon 10g, Squama Manis 20g, Semen Strychni(processed) 200g.
A kind of preparation method that is used for the treatment of the pill of various disorder of joint is characterized in that being finished by following step:
(1) get dry Herba Pyrolae 60g, add water 120g, soak that slow fire boiled 40 minutes after 3 hours, treat that cold slagging-off filters, the filtrate heating is condensed into pasty state, dry Herba Pyrolae concentrated dry powder;
(2) get dry product Radix Aconiti 10g, Radix Aconiti Lateralis 10g, Rhizoma Arisaematis 20g, Rhizoma Zingiberis Recens 5g, add water 450g, rice vinegar 15g soaks that slow fire boiled 20 minutes after 6 hours, remove slag to such an extent that liquid medicine is standby, it is some to get atractylodes rhizome again, and with the ratio of 1g Rhizoma Atractylodis 3ml liquid medicine soak dry after 6 hours Rhizoma Atractylodis;
(3) by Herba Pyrolae concentrated dry powder 10g, Rhizoma Atractylodis 10g, Radix Cyathulae 10g, Olibanum 10g, Myrrha 10g, Scorpio 10g, Bombyx Batryticatus 10g, Agkistrodon 10g, Squama Manis 20g, Semen Strychni(processed) 200g prescription compatibility is fine powder altogether, equivalent Mel, 1200 on conventional one-tenth ball.
Patent medicine theory of the present invention is: though arthrosis a multitude of names is concluded and got up all to belong to traditional Chinese medical science arthromyodynia category.Middle treatment " numbness " is of long standing and well established, current medical science, development in science and technology, means advanced person, new drug emerges in an endless stream,, why but obstinate of all Polyarthropathies? a year clinical experience draws 2 points surplus the inventor long-pending 30: one, aspect the patient, be subjected to factor affecting such as habitat environment, living condition, job specification, labor intensity, injury from falling down situation at the beginning of the disease, I can bear and then bear, can push away then and push away, must be just then, thereby delay treatment, cause and just suffer from into disease of a specified duration.They are two years old, aspect medical, lead to and read doctor's nationality, overview listing side's medicine, its theoretic knowledge, it is all similar to execute the method for controlling, and outer the employing consolidates cold expelling, expelling wind and removing dampness, a surname methods such as network of promoting blood circulation, and when all is said and done, follow the track of the overturned cart, nature will drug effect be similar to like this, therefore, is difficult to occur breaking through on therapeutic effect.Given this, the present invention is new concept more, bases oneself upon " for a long time " word on the treatment arthrosis, has " bitterly " word in mind.Be that the course of disease is of a specified duration, the variation of matter all can take place in its cause of disease, pathogenesis, disease, and pain then is that the first of patient hinders, and positive so-called pathogenic factor is controlled for a long time, stays and does not go, and hematogenous blockage, body fluid condense, and stasis of blood resistance is obstructed, stagnation of QI and blood may bring about pain, the pain utmost point is then idle, idle then with useless also.This moment is if merely dispel the wind simply, cold expelling, dehumidifying then be difficult to prove effective again.So the present invention mainly adopts and invigorates blood circulation, blood stasis dispelling, analgesic Therapeutic Principle, by alleviating or eliminate pain, make the activity thereupon of limited limbs and joint, cause the blood circulation smoothness, energy increases, neurological functional recovery, at this moment, what wind, exopathogen such as cold, wet are removed naturally, and oneself goes out thereby reach the blood sector-style, the stasis of blood is gone to swell and is then disappeared, bitterly then purpose.
The excited maincenter of Semen Strychni is promoted blood circulation in the side, and drug effect is fierce, can search the rheumatism that muscles and bones is situated between to the marrow, the expectorant poison that the flesh side meat of dispelling condenses outward, and the effect of opening the meridians pain relieving far wins its medicine; Squama Manis is apt to away scurry, the merit blood detumescence of specially loosing, the evacuation of pus of assaulting fortified position, the expel wind to dredge collateral sick institute that goes directly; Olibanum is specially invigorated blood circulation, the long diffusing blood of Myrrha, and two medicines share and push away Chen Zhixin, reach blood stasis and give birth to except that fresh blood, and the swollen pain that disappears is only had the wonderful of tonification by oneself; The special wind-damp dispelling the meridian dredging of Agkistrodon merit blood vessel dilating is no matter newly all imitate for a long time; Radix Cyathulae liver and kidney tonifying eliminating stasis to stop pain, the sharp joint of promoting blood circulation to remove obstruction in the collateral; The power of Herba Pyrolae benefit waist kidney bone and muscle strengthening wind-damp dispelling is suitable for getting old and weak and uses it most, and the concentrate drying product draw elite especially, and escalated dose strengthens drug effect; Say " the dead myalgia subcutaneous ulcer of main air cold-damp numbness " in the Rhizoma Atractylodis " herbal classic ", be the key medicine of drying, with black attached star system it, the strong high violent power of suffering that is intended to use black attached star strengthens the merit of its expelling wind and cold; Scorpio, Bombyx Batryticatus be energy expelling wind to relieve convulsion blood stasis-eliminating and stagnation-dissipating all, and the energy blood vessel dilating, convulsion, and heavier rheumatic arthralgia is essential, can resist the toxic and side effects of Semen Strychni again.So medicine-feeding is share and is gathered blood circulation promoting and blood stasis dispelling altogether, removing obstruction in the collateral to relieve pain, liver and kidney tonifying, bone and muscle strengthening, expelling wind and cold, dehumidifying detumescence, logical bones of the body collectively, sharp joint, the effect that complex is used.Be applicable to various joints slight illness, as long as gather effect invariably by taking the course of treatment.
This medicine instructions of taking: high violent because of the efficacy of a drug, so should decide the tolerance degree of medicine on the patient, generally old patient's condition is than the lighter, and each one, every day 2-3 time, young body is strengthened or the heavier tolerance powerhouse of patient's condition, and each two, every day 2 times, 120 is a course of treatment.Boiled water takes after meal.
Criterion of therapeutical effect: cure: the local and position acid of getting involved of focus, fiber crops, swollen, pain complete obiteration, activity freely, functional rehabilitation was not seen the recidivist more than 6 months.Produce effects: acid, fiber crops, swollen, pain disappearance substantially, function is recovered substantially, but the symptom idol has recurrence, and symptom disappears again after the medication, and function is the recuperator thereupon.Effectively: sour, numb, swollen, pain part disappearance, activity dynamics and function make moderate progress, but easy recidivist.Invalid: all diseases do not have obvious improver.
Therapeutic effect: this group case history is totally 1013 examples, wherein male 582 examples, women 431 examples; 30-40 year 169 examples, 41-70 year 768 examples, 71-80 year 76 examples; Be diagnosed as rheumatic arthritis 406 examples, senile degenerative osteoarthritis 109 examples, cervical spondylosis (comprehensively) 167 examples, prolapse of lumbar intervertebral disc 155 examples, lumbar muscle strain 56 examples, sciatica 38 examples, scapulohumeral periarthritis 42 examples, sacral (concealing) splits 8 examples, piriformis syndrome 13 examples, third lumbar vertebra transverse process syndrome 3 examples, rheumatoid arthritis 4 examples, amyotrophic lateral sclerosis 2 examples, ankylosing spondylitis 2 examples, apoplexy sequela 8 examples.The elder of the course of disease 33 years, the shortest person 1 month.By with the treatment of this medicine, cure 952 examples, produce effects 38 examples, effective 11 examples, invalid 2 examples, total effective rate 99.8%.
Model case:
Example 1, Qin Yufu, the man 51 years old, lives the new hedge of Chengde County township, the builder.On November 7th, 1998 went to a doctor, and assisted in and entered the room.Readme: bad pain 3 years is surplus during the waist fashion, and a beginning lumbago increases the weight of gradually, and right side waist hip pain is heavier in recent years, connects and the right thigh outside, and shank also has sense of dragging sometimes, and aching and limp numbness is unable, one month over, puts down and lies on the back passablely, but can not stand up seat.Look into: lie on the back shape still can, the difficulty of changing one's position, unable to get up is sat, and assists upright back lumbar part in and right sacrum portion pain is heavier, the side song is limited, L 2-S 1Right lateral bend, L 3-L 5The back is protruding, and the other tenderness of vertebra sour jujube is obvious, and lower limb and heel radiation to the right.Straight-leg raising test (+), right thigh muscle is lax more unable than the left side, and knee joint and Achilles tendon reflex are hyperfunction, and right female toe back of the body is stretched unable.Doubt to lumbar vertebra lateral bending prolapse of lumbar intervertebral disc, advise its film making.Next day, Chengde Affiliated Hospital sheet showed: L 1-L 2Be right lateral bending, L 3-L 5Recessed disappearance before the physiology, L 3-L 5Protruding behind the intercalated disc, and vertebra sour jujube lip sample becomes, stenosis of disc space is examined and is prolapse of lumbar intervertebral disc and hyperosteogeny.Give this bolus therapy 2 balls/times 2 times/day, after the course of treatment.December patient's further consultation from the beginning on the 5th is said all diseases and is all alleviated, and walks freely.After obeying a course of treatment, 1999 16 days on the 1st, the patient bought medicine from the beginning, said all diseases and did not all have, and obeyed a course of treatment for consolidating again.After visit so far recurrence.
Example 2, Zhang Zhi sends out, and the man 52 years old, lives the Chengde Shuangqiao District, the driver.Went to a doctor the main suit on March 14th, 2002: to sit uncomfortable month of shabby unconscious at ordinary times buttocks surplus because of car, do not draw attention, the first quarter moon cause is got off accidentally, weighs down and squats on ground, and from then on RG and lower limb pain aggravate gradually, very then as lancinate unbearably, and string fiber crops pain appears in the outside behind the lower limb, can not stand up when heavy.Look its limping, obviously outer " eight " word, outward turning duck step.Looking into waist does not have obvious tenderness and tunks carbuncle, and right arm portion HUANTIAO acupoint place tenderness is obvious, can touch obvious streak muscle bundle, and obvious pain before 60 ° of the right side straight-leg raising tests obviously alleviates when surpassing 60 °.The nervous test of piriformis (+) is diagnosed as the piriformis syndrome.The patient is from saying when the time comes, the morbidity back certain hospital look for the expert seen also examining sick for this reason, with relaxing muscles and tendons to promote blood circulation medicine, WANTONG JINGU PIAN, acupuncture 10 days is all invalid again, comes this prescription on individual diagnosis upon somebody's introduction.Advise it to obey this pill 2 balls/times 2 times/day.Promptly heal a course of treatment.
Example 3, the river bank, the man, 38 years old, live the Luanhe River, Chengde town, hold the steel workman, on August 15th, 2003 went to a doctor.Tell waist and pain of buttock is surplus half a year, in time, end when sending out, waist change one's position anteflexion and during lateral bending pain increase the weight of and accompany above-knee radiating pain to the right, treat through several punishments, acupuncture successively 15 days was massaged 10 days, and clothes diclofenac, YAOTONGNING, rheumatic ostalgia sheet, rheumatism horse anter etc. there is no effect.Come this prescription on individual diagnosis upon somebody's introduction.Examine quarter, low-back pain, and the right above-knee radiating pain of the painful companion of arm, waist can not be movable significantly, then alleviates during rest.Look into: right side psoas muscle anxiety, there is obvious tenderness third lumbar vertebra transverse process tip, the right side more so, right arm portion flesh has obvious streak thing, straight-leg raising test (+), the patient does waist and revolves that pain obviously increases the weight of when anteflexion, the abdominal pressure increase does not aggravate the pain.Impression is the third lumbar vertebra syndrome, advises its film making.Next day, X-ray film showed: the third lumbar vertebra transverse process rises appreciably, and the right side is outstanding loose, examines to be third lumbar vertebra transverse process syndrome.Advise clothes this pill 2 balls/times 2 times/day.A course of treatment, JIUYUE further consultation on the 17th, all diseases are removed, take again half the course of treatment medicine to consolidate.
Example 4, Ma Xiaoyun, the woman, 63 years old, live double tower mountain, Chengde, the silk mill workman, JIUYUE was gone to a doctor on the 2nd in 2003, and haltingly, limping is entered the room.Say two knee joint pain 17 years, increased the weight of in nearly 2 years, the bank or serious for a long time on foot that went up a slope, resting for a few days then alleviates, and feels nervous when knee joint is bent and stretched.Look into: the bilateral knee arthroncus is obvious, and a left side is heavier than right, and two Xiyans are full, and flexion and extension is limited, the slight atrophy of quadriceps femoris, and the inboard tenderness of knee joint is obvious, patella grinding test (+).X-ray film shows before looking two month, and the tibia sour jujube comes to a point in the knee joint, and edge, joint lip sample becomes, and right joint space narrows down, and impression is old degeneration (hypertrophy) gonarthritis.Asking its therapeutic process says: acupuncture once for many years, electrotherapy, the various medicines of take are many, as rheumatic ostalgia sheet, WANTONG JINGU PIAN, anti-bone regeneration sheet, Fructus Chaenomelis Pilulae etc., also once play sealing and do not take a turn for the better 3 ends.Advise take a turn for the better 4 healings courses of treatment this pill of clothes 2 balls/time 2 times/day 1 courses of treatment.
The specific embodiment: the present invention is elaborated below in conjunction with embodiment.
Embodiment 1, is used for the treatment of the pill of various disorder of joint, made by following raw materials by weight proportions: Herba Pyrolae concentrated dry powder 10g, Rhizoma Atractylodis 10g, Radix Cyathulae 10g, Olibanum 10g, Myrrha 10g, Scorpio 10g, Bombyx Batryticatus 10g, Agkistrodon 10g, Squama Manis 20g, Semen Strychni(processed) 200g.
Embodiment 2, are used for the treatment of the preparation method of the pill of various disorder of joint, specifically finished by following step:
(1) get dry Herba Pyrolae 60g, add water 120g, soak that slow fire boiled 40 minutes after 3 hours, treat that cold slagging-off filters, the filtrate heating is condensed into pasty state, dry Herba Pyrolae concentrated dry powder;
(2) get dry product Radix Aconiti 10g, Radix Aconiti Lateralis 10g, Rhizoma Arisaematis 20g, Rhizoma Zingiberis Recens 5g, add water 450g, rice vinegar 15g soaks that slow fire boiled 20 minutes after 6 hours, remove slag to such an extent that liquid medicine is standby, it is some to get atractylodes rhizome again, and with the ratio of 1g Rhizoma Atractylodis 3ml liquid medicine soak dry after 6 hours Rhizoma Atractylodis;
(3) by Herba Pyrolae concentrated dry powder 10g, Rhizoma Atractylodis 10g, Radix Cyathulae 10g, Olibanum 10g, Myrrha 10g, Scorpio 10g, Bombyx Batryticatus 10g, Agkistrodon 10g, Squama Manis 20g, Semen Strychni(processed) 200g prescription compatibility, be fine powder (Chinese Pharmacopoeia 8-9 number sieve) altogether, reuse equivalent Mel is made 1200 pills according to the conventional preparation method of honeyed pill medicine, the heavy 0.5g of wherein every ball.
This pill has blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, liver and kidney tonifying, bone and muscle strengthening, expelling wind and cold, dehumidifying detumescence, logical bones of the body collectively, sharp joint, the effect that complex is used.Be applicable to various joints slight illness.

Claims (2)

1, a kind of pill that is used for the treatment of various disorder of joint, it is characterized in that it is made by following raw materials by weight proportions: Herba Pyrolae concentrated dry powder 10g, Rhizoma Atractylodis 10g, Radix Cyathulae 10g, Olibanum 10g, Myrrha 10g, Scorpio 10g, Bombyx Batryticatus 10g, Agkistrodon 10g, Squama Manis 20g, Semen Strychni(processed) 200g.
2, a kind of preparation method that is used for the treatment of the pill of various disorder of joint is characterized in that being finished by following step:
(1) get dry Herba Pyrolae 60g, add water 120g, soak that slow fire boiled 40 minutes after 3 hours, treat that cold slagging-off filters, the filtrate heating is condensed into pasty state, dry Herba Pyrolae concentrated dry powder;
(2) get dry product Radix Aconiti 10g, Radix Aconiti Lateralis 10g, Rhizoma Arisaematis 20g, Rhizoma Zingiberis Recens 5g, add water 450g, rice vinegar 15g soaks that slow fire boiled 20 minutes after 6 hours, remove slag to such an extent that liquid medicine is standby, it is some to get atractylodes rhizome again, and with the ratio of 1g Rhizoma Atractylodis 3ml liquid medicine soak dry after 6 hours Rhizoma Atractylodis;
(3) by Herba Pyrolae concentrated dry powder 10g, Rhizoma Atractylodis 10g, Radix Cyathulae 10g, Olibanum 10g, Myrrha 10g, Scorpio 10g, Bombyx Batryticatus 10g, Agkistrodon 10g, Squama Manis 20g, Semen Strychni(processed) 200g prescription compatibility is fine powder altogether, equivalent Mel, 1200 on conventional one-tenth ball.
CNB2005100127802A 2005-08-30 2005-08-30 Obstruction dredging medicine pill and its prepn Expired - Fee Related CN100349608C (en)

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CN102247409B (en) * 2011-08-18 2012-09-26 潘万领 Traditional Chinese medicine for treating acne and preparation method thereof
CN107596059A (en) * 2017-09-07 2018-01-19 马俊海 A kind of oral pills for treating waist dish outstanding and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1286102A (en) * 2000-09-11 2001-03-07 张国光 'Wanpitong' capsule for treating numbness

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1286102A (en) * 2000-09-11 2001-03-07 张国光 'Wanpitong' capsule for treating numbness

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