CN111973537A

CN111973537A - Whitening and anti-acne facial cleanser and preparation method thereof

Info

Publication number: CN111973537A
Application number: CN202010977028.6A
Authority: CN
Inventors: 黄立新
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-09-16
Filing date: 2020-09-16
Publication date: 2020-11-24

Abstract

The invention discloses a whitening and anti-acne facial cleanser and a preparation method thereof, wherein the whitening and anti-acne facial cleanser comprises the following raw material components: the whitening and disinfecting liquid comprises glycerin, monoalkyl ether phosphate sodium salt, CAB-35, a whitening surfactant, an anti-inflammatory composition, an antioxidant, an emulsifier, a preservative, sodium chloride, essence, deionized water and citric acid, wherein the whitening surfactant comprises lauroyl amidopropyl betaine, hexadecyl betaine, a banana extract and dimethyl silicone oil, and the anti-inflammatory composition comprises a sucrose extract, a hawthorn extract, a grapefruit extract, lipase and butanol. The whitening surfactant is added, the whitening surfactant can inhibit and treat skin problems caused by melanin deposition on the surface of the skin of a human face, so that the purpose of whitening is achieved, and the anti-inflammatory composition is added to achieve the effect of removing acne by killing bacteria on the human face.

Description

Whitening and anti-acne facial cleanser and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to a whitening and anti-acne facial cleanser and a preparation method thereof.

Background

At present, the facial cleanser reaches thousands of households, occupies an important position in the life of people, and has new requirements on life and aesthetic quality along with the increase of the income of people. There is a need in daily washing for a more comfortable, more effective and yet whitening cleanser.

At present, the main components of facial cleansers on the market are surfactants, oily components, water and other components. The facial skin of a human body is fragile, and a plurality of problems are easy to occur. The acne is caused on the face of many people, and often the acne is accompanied with symptoms such as inflammation and red swelling, which are generally caused by bacteria breeding on the face, most of face cleansers mainly achieve the effects of cleaning the face and removing cutin, some of the face cleansers can be added with additives to achieve the purpose of moisturizing the skin, but the oil control cannot help for the bacteria breeding. With the development of the current society, the aesthetic value of people is continuously improved, so that the development of the whitening and anti-acne facial cleanser is very important.

Disclosure of Invention

The invention aims to provide a whitening and anti-acne facial cleanser and a preparation method thereof, and aims to solve the problems in the background technology.

In order to solve the technical problems, the invention provides the following technical scheme:

the whitening and anti-acne facial cleanser comprises, by weight, 15-20 parts of glycerin, 25-35 parts of monoalkyl ether phosphate sodium salt, 25-7 parts of CAB-355, 10-15 parts of whitening surfactant, 1-2 parts of an anti-inflammatory composition, 5-7 parts of an antioxidant, 2.5-3.5 parts of an emulsifier, 4-5 parts of a preservative, 2-5 parts of sodium chloride, 0.5-1 part of essence, 40-50 parts of deionized water and 2-5 parts of citric acid.

Further, the whitening surfactant is mainly prepared from lauroyl amide propyl betaine, hexadecyl betaine, a banana extract and dimethyl silicone oil.

Furthermore, the anti-inflammatory composition is mainly prepared from sucrose extract, hawthorn extract, grapefruit extract, lipase and butanol.

Furthermore, the antioxidant comprises, by weight, 5-10 parts of SOD, 1-5 parts of vitamin E and 1-5 parts of vitamin A.

Furthermore, the emulsifier comprises the following raw material components, by weight, 0.5-1 part of sorbitan monopalmitate and 1-3 parts of lanolin alcohol.

Furthermore, the preservative comprises the following raw material components, by weight, 4-5 parts of phenoxyethanol, 0.1-0.5 part of methyl paraben and 0.1-0.5 part of propyl paraben.

The betaine-betaine system can be used for improving the stability of the whitening component system, and the silicone oil can be used as a carrier of the banana extract to improve the whitening effect.

A preparation method of a whitening and anti-acne facial cleanser comprises the following steps of preparing a whitening surfactant:

heating deionized water, adding lauroyl amide propyl betaine, controlling temperature at 50-55 deg.C, stirring at 200r/min until lauroyl amide propyl betaine is dissolved, controlling temperature at 50-55 deg.C, and stirring at 100r/min to obtain solution A;

mixing the banana extract with dimethyl silicone oil, stirring at 40-45 deg.C for 200r/min, stirring for 3-5min, and cooling to obtain solution B;

slowly cooling the solution A, keeping stirring at 100r/min, adding the solution B when the solution A is cooled to 30 ℃, cooling to 20-25 ℃, and adding sodium chloride to adjust viscosity to obtain the whitening surfactant.

Further, an anti-inflammatory composition is prepared by the following steps:

adding lipase into monopotassium phosphate solution, adding silica gel, fixing lipase on silica gel, adding protein, controlling temperature at 20-23 deg.C, slowly stirring for 100r/min, stirring for 5min, filtering, washing with water, drying at 23-25 deg.C, adding butanol and molecular sieve, adding fructus crataegi extract and fructus Citri Grandis extract, mixing at 23-25 deg.C and 150r/min under stirring to obtain solution C;

filtering the solution C by using 0.3mm filter paper, vacuumizing and heating to 40-45 ℃, evaporating for 30min to obtain a solid A, adding cyclohexane into the solid A for four times of extraction, centrifuging the solid B after each extraction, standing for 20-30min at room temperature, extracting for four times to obtain a solid B, washing the solid B by using deionized water, centrifuging to obtain a solid C, and mixing a sucrose extract with the solid C to obtain the anti-inflammatory composition.

Further, a finished product is prepared by the following steps:

heating deionized water to 60-65 ℃ at constant temperature, adding monoalkyl ether phosphate sodium salt, controlling the temperature to 60-65 ℃, continuously stirring until the mixture is completely dissolved, controlling the temperature to 60-65 ℃, keeping continuous stirring at 100r/min, and adding CAB-35 until the mixture is completely dissolved to obtain a solution B;

cooling the solution B to 50-55 ℃, adding glycerol and an emulsifier, and slowly stirring to dissolve; cooling to 40 deg.C, adding perfume, antiseptic, and whitening surfactant;

measuring pH value, and adjusting pH to 6-7 with citric acid;

adding the anti-inflammatory composition when the temperature is reduced to 25-30 deg.C;

when the temperature is reduced to 23-25 ℃, sodium chloride is added to adjust the viscosity, and the whitening and anti-acne facial cleanser is obtained.

Compared with the prior art, the invention has the following beneficial effects: the important effects of the facial cleanser are not only facial cleansing but also whitening, the whitening components are deteriorated and the absorption capacity of the whitening components is different from person to person due to the change of environmental factors in the daily use process, the whitening components are often single and have little content in the traditional facial cleanser, the traditional facial cleanser is not very careful considering the environmental factors, only some preservatives are added, the traditional facial cleanser is not treated any more, sometimes, the whitening components and the preservatives have multiple reactions, and the facial allergy of a user can be caused when the whitening components and the preservatives are serious, the whitening surfactant added in the facial cleanser solves the problem, the whitening active agent mainly plays a role in preparing the banana extract, the dimethicone can be better absorbed by the skin of a human body, the banana extract can be better absorbed by the skin as a carrier for the banana extract, and the addition of the lauroyl amido propyl betaine and the hexadecyl betaine can maintain the stability of the banana extract-silicone oil system, on the other hand, the viscosity of the banana extract-silicone oil system can be improved, and the whitening nutrient attached to the dimethicone is protected from being contacted with other substances, so that the side reaction can be reduced, and the applicability of different skins is improved by adding the dimethicone. Compared with the traditional facial cleanser, most of the traditional facial cleansers only simply add vitamin C and other additives for acne treatment and do not consider whether the additives kill bacteria on inflamed parts of the face and whether the additives deteriorate in normal use, people only start to have good effects after long-time use of the traditional facial cleansers, the effects are worse and even no, the effects are increased along with the increase of the use time and times, the anti-inflammatory composition added into the facial cleanser can solve the problem, the anti-inflammatory composition mainly plays a role in hawthorn extract and grapefruit extract, the hawthorn extract and the grapefruit extract contain vitamin C, the vitamin C can kill the bacteria on the inflamed parts of the face, but the vitamin C is unstable and has strict requirements on the environment, and therefore, butanol can react with the vitamin C, the vitamin C acid ester is generated under the condition that lipase is used as a catalyst, the vitamin C derivative is more stable, the sterilization effect is better than that of the vitamin C, the content of the vitamin C and the vitamin C derivative is more stable in the using process, therefore, the sterilization effect can be ensured in the long-term using process, the content of butanol is less than that of the vitamin C, so that the vitamin C with little residual content can be generated in a sample, the facial cleanser inevitably contacts with air in the using process, the vitamin C is easily oxidized, and therefore, the sucrose extract is added, glucose substances contained in the sucrose extract can be preferentially oxidized with oxygen, the content of the vitamin C in the sample is protected, and the effect is better.

Detailed Description

The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

The whitening anti-acne facial cleanser comprises the following raw materials, by weight, 15 parts of glycerin, 25 parts of monoalkyl ether phosphate sodium salt, 25 parts of CAB-355 parts of whitening surfactant, 10 parts of anti-inflammatory composition, 5 parts of antioxidant, 2.5 parts of emulsifier, 4 parts of preservative, 2 parts of sodium chloride, 0.5 part of essence, 40 parts of deionized water and 2 parts of citric acid.

The whitening surfactant is mainly prepared from lauroyl amide propyl betaine, hexadecyl betaine, a banana extract and dimethyl silicone oil.

The anti-inflammatory composition is mainly prepared from sucrose extract, hawthorn extract, grapefruit extract, lipase and butanol.

The antioxidant comprises the following raw material components, by weight, 5 parts of SOD, 1 parts of vitamin E and 1 part of vitamin A.

The emulsifier comprises the following raw material components, by weight, 0.5 part of sorbitan monopalmitate and 1 part of lanolin alcohol.

The preservative comprises the following raw material components, by weight, 4 parts of phenoxyethanol, 0.1 part of methyl paraben and 0.1 part of propyl paraben.

A preparation method of the whitening and anti-acne facial cleanser comprises the following steps:

(1) heating deionized water, adding lauroyl amide propyl betaine, controlling the temperature at 50 ℃, stirring at 200r/min until the lauroyl amide propyl betaine is dissolved, then controlling the temperature at 50 ℃, and stirring at 100r/min, and adding hexadecyl betaine to obtain a solution A;

mixing the banana extract with dimethyl silicone oil, stirring at 40 deg.C for 200r/min, stirring for 3min, and cooling to obtain solution B;

slowly cooling the solution A, keeping stirring at 100r/min, adding the solution B when the solution A is cooled to 30 ℃, cooling to 20 ℃, and adding sodium chloride to adjust viscosity to prepare the whitening surfactant.

(2) Adding lipase into monopotassium phosphate solution, adding silica gel, fixing lipase on silica gel, adding protein, controlling temperature at 20 deg.C, slowly stirring for 100r/min, stirring for 5min, filtering, washing with water, drying at 23 deg.C, adding butanol and molecular sieve, adding fructus crataegi extract and fructus Citri Grandis extract, and mixing at 23 deg.C and 150r/min under stirring to obtain solution C;

filtering the solution C by using 0.3mm filter paper, vacuumizing, heating to 40 ℃, evaporating for 30min to obtain a solid A, adding cyclohexane into the solid A for four times of extraction, centrifuging the solid B after each extraction, standing for 20min at room temperature, extracting for four times to obtain a solid B, washing the solid B by using deionized water, centrifuging to obtain a solid C, and mixing a sucrose extract with the solid C to obtain the anti-inflammatory composition.

(3) Heating deionized water to 60 ℃ at constant temperature, then adding monoalkyl ether phosphate sodium salt, controlling the temperature to 60 ℃, continuously stirring until the mixture is completely dissolved, controlling the temperature to 60 ℃, keeping continuous stirring at 100r/min, and adding CAB-35 until the mixture is completely dissolved to obtain a solution B;

(4) cooling the solution B to 50 ℃, adding glycerol and an emulsifier, and slowly stirring to dissolve the glycerol and the emulsifier; cooling to 40 deg.C, adding perfume, antiseptic, and whitening surfactant;

(5) measuring pH value, and adjusting pH to 6 with citric acid;

(6) adding the anti-inflammatory composition when the temperature is reduced to 25 deg.C;

(7) when the temperature is reduced to 23 ℃, sodium chloride is added to adjust the viscosity, and the whitening and anti-acne facial cleanser is obtained.

Example 2

The whitening anti-acne facial cleanser comprises, by weight, 17 parts of glycerin, 30 parts of monoalkyl ether phosphate sodium salt, CAB-356 parts of whitening surfactant, 1.5 parts of an anti-inflammatory composition, 6 parts of an antioxidant, 3 parts of an emulsifier, 4.5 parts of a preservative, 4 parts of sodium chloride, 0.6 part of an essence, 45 parts of deionized water and 3 parts of citric acid.

The antioxidant comprises the following raw material components, by weight, 6 parts of SOD, 3 parts of vitamin E and 3 parts of vitamin A.

The emulsifier comprises the following raw material components, by weight, 0.7 part of sorbitan monopalmitate and 2 parts of lanolin alcohol.

The preservative comprises the following raw material components, by weight, 4.5 parts of phenoxyethanol, 0.3 part of methyl paraben and 0.3 part of propyl paraben.

(1) heating deionized water, adding lauroyl amide propyl betaine, controlling the temperature at 53 deg.C, stirring at 200r/min until the lauroyl amide propyl betaine is dissolved, controlling the temperature at 53 deg.C, and stirring at 100r/min to obtain solution A;

mixing the banana extract with dimethyl silicone oil, stirring at 43 deg.C for 200r/min, stirring for 4min, and cooling to obtain solution B;

slowly cooling the solution A, keeping stirring at 100r/min, adding the solution B when the solution A is cooled to 30 ℃, cooling to 23 ℃, and adding sodium chloride to adjust viscosity to prepare the whitening surfactant.

(2) Adding lipase into monopotassium phosphate solution, adding silica gel, fixing lipase on silica gel, adding protein, controlling temperature at 22 deg.C, slowly stirring for 100r/min, stirring for 5min, filtering, washing with water, drying at 24 deg.C, adding butanol and molecular sieve, adding fructus crataegi extract and fructus Citri Grandis extract, and mixing at 24 deg.C and 150r/min under stirring to obtain solution C;

filtering the solution C by using 0.3mm filter paper, vacuumizing and heating to 43 ℃ for evaporating for 30min to obtain a solid A, adding cyclohexane into the solid A for four times of extraction, centrifuging the solid B after each extraction, standing for 25min at room temperature, extracting for four times to obtain a solid B, washing the solid B by using deionized water, centrifuging to obtain a solid C, and mixing the sucrose extract and the solid C to obtain the anti-inflammatory composition.

(3) Heating deionized water to 63 ℃ at constant temperature, then adding monoalkyl ether phosphate sodium salt, controlling the temperature to 63 ℃, continuously stirring until the mixture is completely dissolved, controlling the temperature to 63 ℃, keeping the continuous stirring at 100r/min, and adding CAB-35 until the mixture is completely dissolved to obtain a solution B;

(4) cooling the solution B to 52 ℃, adding glycerol and an emulsifier, and slowly stirring to dissolve the glycerol and the emulsifier; cooling to 40 deg.C, adding perfume, antiseptic, and whitening surfactant;

(5) measuring pH value, and adjusting pH to 6 with citric acid;

(6) adding the anti-inflammatory composition when the temperature is reduced to 26 deg.C;

(7) when the temperature is reduced to 24 ℃, sodium chloride is added to adjust the viscosity, and the whitening and anti-acne facial cleanser is obtained.

Example 3

The whitening and anti-acne facial cleanser comprises, by weight, 20 parts of glycerin, 35 parts of monoalkyl ether phosphate sodium salt, 357 parts of CAB-357 parts of whitening surfactant, 2 parts of an anti-inflammatory composition, 7 parts of an antioxidant, 3.5 parts of an emulsifier, 5 parts of a preservative, 5 parts of sodium chloride, 0.5-1 part of essence, 50 parts of deionized water and 5 parts of citric acid.

The antioxidant comprises the following raw material components, by weight, 10 parts of SOD, 5 parts of vitamin E and 5 parts of vitamin A.

The emulsifier comprises the following raw material components, by weight, 1 part of sorbitan monopalmitate and 3 parts of lanolin alcohol.

The preservative comprises the following raw material components, by weight, 5 parts of phenoxyethanol, 0.5 part of methyl paraben and 0.5 part of propyl paraben.

(1) heating deionized water, adding lauroyl amide propyl betaine, controlling temperature at 55 deg.C, stirring at 200r/min until lauroyl amide propyl betaine is dissolved, controlling temperature at 55 deg.C, and stirring at 100r/min to obtain solution A;

mixing the banana extract with dimethyl silicone oil, stirring at 45 deg.C for 200r/min, stirring for 5min, and cooling to obtain solution B;

slowly cooling the solution A, keeping stirring at 100r/min, adding the solution B when the solution A is cooled to 30 ℃, cooling to 25 ℃, and adding the sodium chloride to adjust the viscosity to obtain the whitening surfactant.

(2) Adding lipase into monopotassium phosphate solution, adding silica gel, fixing lipase on silica gel, adding protein, controlling temperature at 23 deg.C, slowly stirring for 100r/min, stirring for 5min, filtering, washing with water, drying at 25 deg.C, adding butanol and molecular sieve, adding fructus crataegi extract and fructus Citri Grandis extract, and mixing at 25 deg.C and 150r/min under stirring to obtain solution C;

filtering the solution C by using 0.3mm filter paper, vacuumizing and heating to 45 ℃ for evaporating for 30min to obtain a solid A, adding cyclohexane into the solid A for four times of extraction, centrifuging the solid B after each extraction, standing for 30min at room temperature, extracting for four times to obtain a solid B, washing the solid B by using deionized water, centrifuging to obtain a solid C, and mixing the sucrose extract and the solid C to obtain the anti-inflammatory composition.

(3) Heating deionized water to 65 ℃ at constant temperature, then adding monoalkyl ether phosphate sodium salt, controlling the temperature to 65 ℃, continuously stirring until the mixture is completely dissolved, controlling the temperature to 65 ℃, and adding CAB-35 to the mixture to be completely dissolved under the continuous stirring of 100r/min to obtain a solution B;

(4) cooling the solution B to 55 ℃, adding glycerol and an emulsifier, and slowly stirring to dissolve the glycerol and the emulsifier; cooling to 40 deg.C, adding perfume, antiseptic, and whitening surfactant;

(5) measuring pH value, and adjusting pH to 7 with citric acid;

(6) adding the anti-inflammatory composition when the temperature is reduced to 30 deg.C;

(7) when the temperature is reduced to 25 ℃, sodium chloride is added to adjust the viscosity, and then the whitening and anti-acne facial cleanser is obtained.

Comparative example 1

The whitening and anti-acne facial cleanser comprises, by weight, 20 parts of glycerin, 35 parts of monoalkyl ether phosphate sodium salt, CAB-357 parts of banana extract, 2 parts of an anti-inflammatory composition, 7 parts of an antioxidant, 3.5 parts of an emulsifier, 5 parts of a preservative, 5 parts of sodium chloride, 0.5-1 part of essence, 50 parts of deionized water and 5 parts of citric acid.

(1) adding lipase into monopotassium phosphate solution, adding silica gel, fixing lipase on silica gel, adding protein, controlling temperature at 23 deg.C, slowly stirring for 100r/min, stirring for 5min, filtering, washing with water, drying at 25 deg.C, adding butanol and molecular sieve, adding fructus crataegi extract and fructus Citri Grandis extract, and mixing at 25 deg.C and 150r/min under stirring to obtain solution C;

(2) Heating deionized water to 65 ℃ at constant temperature, adding monoalkyl ether phosphate sodium salt, controlling the temperature to 65 ℃, continuously stirring until the mixture is completely dissolved, controlling the temperature to 65 ℃, and adding CAB-35 to the mixture to be completely dissolved under the continuous stirring of 100r/min to obtain a solution B;

(3) cooling the solution B to 55 ℃, adding glycerol and an emulsifier, and slowly stirring to dissolve the glycerol and the emulsifier; cooling to 40 deg.C, adding spice, antiseptic, and fructus Musae extract;

(4) measuring pH value, and adjusting pH to 7 with citric acid;

(5) adding the anti-inflammatory composition when the temperature is reduced to 30 deg.C;

(6) when the temperature is reduced to 25 ℃, sodium chloride is added to adjust the viscosity, and the whitening and anti-acne facial cleanser is obtained.

Comparative example 2

The whitening and anti-acne facial cleanser comprises, by weight, 20 parts of glycerin, 35 parts of monoalkyl ether phosphate sodium salt, 357 parts of CAB-357 parts of an anti-inflammatory composition, 2 parts of an antioxidant, 3.5 parts of an emulsifier, 5 parts of a preservative, 5 parts of sodium chloride, 0.5-1 part of essence, 50 parts of deionized water and 5 parts of citric acid.

(2) Heating deionized water to 65 ℃ at constant temperature, adding monoalkyl ether phosphate sodium salt, controlling the temperature to 65 ℃, continuously stirring until the mixture is completely dissolved, controlling the temperature to 65 ℃, keeping continuous stirring at 100r/min, and adding CAB-35 until the mixture is completely dissolved to obtain a solution B;

(3) cooling the solution B to 55 ℃, adding glycerol and an emulsifier, and slowly stirring to dissolve the glycerol and the emulsifier; cooling to 40 deg.C, adding perfume, antiseptic, and whitening surfactant;

(4) measuring pH value, and adjusting pH to 7 with citric acid;

(6) when the temperature is reduced to 25 ℃, sodium chloride is added to adjust the viscosity, and then the whitening and anti-acne facial cleanser is obtained.

Comparative example 3

The whitening and anti-acne facial cleanser comprises, by weight, 20 parts of glycerin, 35 parts of monoalkyl ether phosphate sodium salt, CAB-357 parts of whitening surfactant, 15 parts of sucrose extract, hawthorn extract, grapefruit extract, 7 parts of antioxidant, 3.5 parts of emulsifier, 5 parts of preservative, 5 parts of sodium chloride, 0.5-1 part of essence, 50 parts of deionized water and 5 parts of citric acid.

slowly cooling the solution A, keeping stirring at 100r/min, adding the solution B when the solution A is cooled to 30 ℃, cooling to 25 ℃, and adding sodium chloride to adjust viscosity to prepare the whitening surfactant.

(4) measuring pH value, and adjusting pH to 7 with citric acid;

(5) adding sucrose extract, fructus crataegi extract, and fructus Citri Grandis extract when the temperature is reduced to 30 deg.C;

Comparative example 4

The whitening and anti-acne facial cleanser comprises, by weight, 20 parts of glycerin, 35 parts of monoalkyl ether phosphate sodium salt, 357 parts of CAB-357 parts of whitening surfactant, 7 parts of antioxidant, 3.5 parts of emulsifier, 5 parts of preservative, 5 parts of sodium chloride, 0.5-1 part of essence, 50 parts of deionized water and 5 parts of citric acid.

(4) measuring pH value, and adjusting pH to 7 with citric acid;

(5) when the temperature is reduced to 25 ℃, sodium chloride is added to adjust the viscosity, and the whitening and anti-acne facial cleanser is obtained.

Control test:

1. comparative experiments were carried out for examples 1, 2, 3, 1, 2:

in order to verify that the obtained facial cleanser has a good whitening effect, 90 volunteers are selected, and the age is 35-45 years old, and the facial cleanser is accompanied by symptoms of facial melanin deposition. The test was performed by dividing 150 volunteers into three groups of 30 persons, and the melanin deposition values of the volunteers were tested by using a multi-parameter skin tester M150/callegari. The test time was 4 weeks, and the test was performed once a week, and the test results were as follows:

	before use	Is used for one week	Is used for two weeks	Using for three weeks	Use all around
						Example 1	184	170	163	154	146
Example 2	186	172	168	152	143
						Example 3	180	173	165	150	145
Comparative example 1	175	170	164	160	163
						Comparative example 2	173	170	175	170	168

Watch 1

2. Comparative experiments were carried out for example 1, example 2, example 3, comparative example 4:

in order to verify that the obtained sample has the bactericidal effect, the main bacteria of the human facial inflammation is staphylococcus aureus, so that the staphylococcus aureus test is passed.

The test is carried out under the condition of ensuring the indoor sterility, the culture dish is sterilized and disinfected, nutrient agar is added into the culture dish, the staphylococcus aureus is diluted by 1:10, 10mL is inoculated into the nutrient agar culture dish, nutrient components such as glucose, protein and water are added to obtain a staphylococcus aureus culture dish, the staphylococcus aureus culture dish is placed at 35 +/-2 ℃ for 24 hours to obtain a finished staphylococcus aureus culture dish, 15 parts of staphylococcus aureus culture dishes are manufactured according to the method, then, the example 1, the example 2, the example 3, the comparative example 3 and the comparative example 4 are diluted by 1:10, 10mL are added into each staphylococcus aureus culture dish, each 3 parts are cultured at the temperature of 27 +/-1 ℃, and the result after 12 hours is shown in a table two.

	Before dropping sample (CFU/mL)	After dropping the sample (CFU/mL)
			Example 1	2549	1106
Example 2	2645	1195
			Example 3	2490	1040
Comparative example 3	2680	1650
			Comparative example 4	2450	1980

Watch two

Results of the control test:

as can be seen from table one, the inhibitory ability and the treatment ability to melanin deposition symptom of example 1, example 2, and example 3 are the best, and with respect to example 1, example 2, and example 3, comparative example 1 has the same treatment ability as examples 1, 2, and 3 in the first week and the second week, but the treatment ability becomes slow and even tends to increase from the third week, and the inhibitory and the treatment ability second, which indicates that the absorption ability of skin to nutrients is limited, and the use of dimethicone is effective for increasing the absorption rate, and the inhibitory and the treatment ability to melanin deposition symptom of comparative example 2 is not effective, and thus the worst is exhibited. The excellent treatment ability and sustained treatment ability of examples 1, 2 and 3 for melanin deposition symptoms were experimentally shown.

As can be seen from the second table, the sterilization effect of the samples on Staphylococcus aureus under higher temperature conditions is excellent in examples 1, 2 and 3, and the number of colonies is remarkably reduced, and in comparative example 3, the worst is comparative example 4. Experiments show that the sterilization capacity of example 3 for staphylococcus aureus is excellent, which shows that the addition of the substance for maintaining the stability of vitamin C and preventing the vitamin C from deteriorating due to the change of the external temperature is effective, and the sterilization capacity can be improved, so that the anti-inflammatory effect on facial skin inflammation can be achieved.

And (3) error analysis:

for experiment one: experiment one error exists in that the effect is caused by different facial melanin values of each person and the absorption capacity of each person's skin to nutrient substances is different, so that the experiment has errors, but the experiment data is obtained through an average value, and the error can be reduced.

For experiment two: the second error that exists of experiment lies in bacterial colony number and bacterial colony number wood in experimental environment air and can produce some errors through artifical the count, but this experiment every has set up 3, can reduce the error after getting the average.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A whitening and anti-acne facial cleanser is characterized in that; the whitening anti-acne facial cleanser comprises, by weight, 15-20 parts of glycerin, 25-35 parts of monoalkyl ether phosphate sodium salt, 25-7 parts of CAB-355, 10-15 parts of a whitening surfactant, 1-2 parts of an anti-inflammatory composition, 5-7 parts of an antioxidant, 2.5-3.5 parts of an emulsifier, 4-5 parts of a preservative, 2-5 parts of sodium chloride, 0.5-1 part of an essence, 40-50 parts of deionized water and 2-5 parts of citric acid.

2. The whitening and anti-acne facial cleanser according to claim 1, characterized in that: the whitening surfactant is mainly prepared from lauroyl amide propyl betaine, hexadecyl betaine, a banana extract and dimethyl silicone oil.

3. The whitening and anti-acne facial cleanser according to claim 1, characterized in that: the anti-inflammatory composition is mainly prepared from sucrose extract, hawthorn extract, grapefruit extract, lipase and butanol.

4. The whitening and anti-acne facial cleanser according to claim 1, characterized in that: the antioxidant comprises, by weight, 5-10 parts of SOD, 5-5 parts of vitamin E1 and 5-5 parts of vitamin A1.

5. The whitening and anti-acne facial cleanser according to claim 1, characterized in that: the emulsifier comprises the following raw material components, by weight, 0.5-1 part of sorbitan monopalmitate and 1-3 parts of lanolin alcohol.

6. The whitening and anti-acne facial cleanser according to claim 1, characterized in that: the preservative comprises the following raw material components, by weight, 4-5 parts of phenoxyethanol, 0.1-0.5 part of methyl paraben and 0.1-0.5 part of propyl paraben.

7. A preparation method of the whitening and anti-acne facial cleanser is characterized by comprising the following steps: comprises the following steps:

(1) preparing a whitening surfactant;

(2) preparing an anti-inflammatory composition;

(3) and preparing a finished product.

8. The preparation method of the whitening and anti-acne facial cleanser according to claim 7 is characterized in that: the whitening surfactant is prepared by the following steps:

heating deionized water, adding lauroyl amide propyl betaine, controlling the temperature at 50-55 deg.C, stirring at 200r/min until lauroyl amide propyl betaine is dissolved, controlling the temperature at 50-55 deg.C, and adding hexadecyl betaine at 100r/min to obtain solution A;

9. The preparation method of the whitening and anti-acne facial cleanser according to claim 7 is characterized in that: the (2) preparing the anti-inflammatory composition comprises the following steps:

adding lipase into monopotassium phosphate solution, adding silica gel, fixing lipase on silica gel, adding protein, controlling temperature at 20-23 deg.C, slowly stirring for 100r/min, stirring for 5min, filtering, washing with water, drying at 23-25 deg.C, adding butanol and molecular sieve, adding fructus crataegi extract and fructus Citri Grandis extract, mixing at 23-25 deg.C and 150r/min to obtain solution C;

filtering the solution C with 0.3mm filter paper, vacuumizing, heating to 40-45 ℃, evaporating for 30min to obtain a solid A, adding cyclohexane into the solid A for four times of extraction, centrifuging the solid B after each extraction, standing for 20-30min at room temperature, extracting for four times to obtain a solid B, washing the solid B with deionized water, centrifuging to obtain a solid C, and mixing the sucrose extract and the solid C to obtain the anti-inflammatory composition.

10. The preparation method of the whitening and anti-acne facial cleanser according to claim 7 is characterized in that: the step (3) of preparing a finished product comprises the following steps:

measuring pH value, and adjusting pH to 6-7 with citric acid;