CN111888405A - Traditional Chinese medicine composition for contracting and tightening vagina and preparation method and application thereof - Google Patents

Traditional Chinese medicine composition for contracting and tightening vagina and preparation method and application thereof Download PDF

Info

Publication number
CN111888405A
CN111888405A CN202010958409.XA CN202010958409A CN111888405A CN 111888405 A CN111888405 A CN 111888405A CN 202010958409 A CN202010958409 A CN 202010958409A CN 111888405 A CN111888405 A CN 111888405A
Authority
CN
China
Prior art keywords
parts
extract
traditional chinese
chinese medicine
tightening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010958409.XA
Other languages
Chinese (zh)
Inventor
刘春辉
李自托
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Haoer Biotechnology Co ltd
Original Assignee
Beijing Haoer Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Haoer Biotechnology Co ltd filed Critical Beijing Haoer Biotechnology Co ltd
Priority to CN202010958409.XA priority Critical patent/CN111888405A/en
Publication of CN111888405A publication Critical patent/CN111888405A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/264Aristolochia (Dutchman's pipe)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Animal Husbandry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a traditional Chinese medicine composition containing vagina for contracting and tightening, a preparation method and application thereof, and belongs to the technical field of medicine and health. The traditional Chinese medicine composition for contracting and tightening the vagina is characterized by mainly comprising the following components in parts by weight: 1-10 parts of gallnut extract, 1-10 parts of pomegranate bark extract, 1-10 parts of lime fruit extract, 1-10 parts of dogwood extract, 1-10 parts of centella asiatica extract, 1-20 parts of propylene glycol and 1-20 parts of deionized water. The traditional Chinese medicine composition for contracting and tightening the vagina provided by the invention is prepared from natural traditional Chinese medicines, is refined, is scientifically matched, and has synergistic effect; has the effects of improving the activity of vaginal smooth muscle, increasing elasticity, repairing the injury of the intima at the private part, resisting the aging of the private part, and fading black and tender, can take effect after being used for 5-7 days, and can make the private part remold and compact and recover as the private part; the medicine has the advantages of safety, high efficiency, no side effect, no medicine residue, difficult generation of medicine resistance, convenient use and the like, and can be widely applied to private compact products.

Description

Traditional Chinese medicine composition for contracting and tightening vagina and preparation method and application thereof
Technical Field
The invention relates to a traditional Chinese medicine composition for contracting and tightening vagina, a preparation method and application thereof, and belongs to the technical field of medicine and health.
Background
The vagina is a muscular duct composed of mucosa, muscular layer and adventitia, rich in extensibility, connecting the uterus and external genitalia. Vaginal relaxation is a physiological condition of women with age, birth is the watershed of female vaginal relaxation, and most women face the problem of vaginal relaxation in different degrees after birth. Vaginal relaxation refers to the decrease in tension of pelvic muscle groups, which results in relaxation of muscles around the vagina and widening of the vagina.
Vaginal relaxation can cause gynecological troubles such as weakness in grip, decreased quality of sexual life, vaginal inflammation and the like, lead to premature senility of women, and cause flatus vaginae, urine leakage, uterine prolapse, even vaginal prolapse and the like. Therefore, the female is worried a lot, and becomes the pain of the female who can not erase the heart and the embarrassment of not exporting the heart. The reasons for vaginal relaxation are mainly: spontaneous childbirth, age, frequent sexual life, less exercise, abortion, spontaneous relaxation, etc. The laxity of vagina becomes a big enemy of female sexual welfare, so the maintenance of female private parts can be not eased!
At present, the common approaches for tightening private parts include the following five approaches: the operation (I) comprises the following steps: effective, but high cost, long and difficult nursing of postoperative mucosa wound, easy infection, certain risk and pain bearing, poor vagina elasticity and no production. (II) injection: the duration is short, and complications may be induced. And (III) basic reproduction health maintenance and nursing: weak effect and long treatment course. (IV) instruments: has certain effect, but foreign matters enter the body and burn the mucosa in the private part, so the problems of elasticity and wettability cannot be solved. (V) stopping feeding drugs: the chemical drugs are abundant, have large side effects and dependence in short time, and can thin the inner wall of the private part and permanently relax the self-contraction function after long-term use.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides the traditional Chinese medicine composition for contracting and tightening the vagina, and the preparation method and the application thereof, the traditional Chinese medicine composition can quickly contract the vagina, repair the vaginal intimal injury, enhance the elasticity and resist the private part aging, and has the advantages of safety, high efficiency, no side effect, convenient use and the like.
The invention provides a traditional Chinese medicine composition for contracting and tightening vagina, which is characterized by comprising the following components in parts by mass: 1-10 parts of gallnut extract, 1-10 parts of pomegranate bark extract, 1-10 parts of lime fruit extract, 1-10 parts of dogwood extract, 1-10 parts of centella asiatica extract, 1-20 parts of propylene glycol and 1-20 parts of deionized water.
The Galla chinensis extract has effects in reducing yin, tightening body, removing toxic substance, repairing mucosa injury, stopping bleeding, and promoting metabolism; the pericarpium Granati extract has functions of astringing and reducing vagina, and is a pudendum cleaning holy product; the fructus Aurantii Immaturus extract can induce vaginal contraction, inhibit uterine prolapse, and invigorate qi; the Corni fructus extract has effects of resisting oxidation, scavenging free radicals, regulating immunity, removing melanin pigmentation, and regenerating cell to make private parts tender; the herba Centellae extract can promote collagen regeneration, enhance basal layer cell activity, and repair skin elasticity and compactness.
The traditional Chinese medicine composition for contracting and tightening the vagina is characterized by comprising the following components in parts by mass: 1-10 parts of gallnut extract, 1-10 parts of pomegranate bark extract, 1-10 parts of lime fruit extract, 1-10 parts of dogwood extract, 1-10 parts of centella extract, 1-20 parts of propylene glycol, 1-20 parts of deionized water, 1-10 parts of bisabolol extract, 1-10 parts of dutchmanspipe root extract, 1-10 parts of pericarpium zanthoxyli extract, 1-10 parts of clove extract, 1-10 parts of radix angelicae extract and 1-10 parts of fructus liquidambaris extract.
The preparation method of the traditional Chinese medicine composition for contracting and tightening the vagina is characterized by comprising the following steps of:
(1) selecting and cleaning the traditional Chinese medicine raw materials respectively, drying at 40-60 ℃, and cutting into pieces with the size of 2-4 cm2Small pieces of (2);
(2) soaking gallnut, pomegranate rind, orange fruit, dogwood, myrrh, clove, dutchmanspipe root, pericarpium zanthoxyli and sweetgum fruit in 8-10 times of deionized water for 24 hours respectively, then performing ultrasonic extraction at 40-50 ℃ for 4 hours, filtering, performing ultrasonic extraction on filter residues for 4 hours at 40-50 ℃ by using 6-8 times of water, combining filtrates obtained in 2 times, and concentrating the filtrates of the traditional Chinese medicines to proper volumes at about 50 ℃ respectively to obtain traditional Chinese medicine extracting solutions;
(3) soaking centella asiatica in 8-10 times of 70-90% ethanol solution for 24 hours, then performing reflux extraction at 30-60 ℃ for 6 hours, filtering, extracting filter residues with 6-8 times of 70-90% ethanol solution at 30-60 ℃ for 6 hours, combining filtrates, concentrating to remove ethanol, and concentrating to a proper volume to obtain a centella asiatica extract;
(4) weighing a proper amount of the extract according to a proportion, then adding a proper amount of propylene glycol and deionized water, and uniformly mixing to obtain the traditional Chinese medicine composition for contracting and tightening vagina.
The traditional Chinese medicine composition for contracting and tightening the vagina is characterized by being applied to medicines or disinfectants or washing and protecting products.
The application of the traditional Chinese medicine composition for contracting and tightening the vagina is characterized in that the usage amount of the traditional Chinese medicine composition in a medicine or a disinfectant or a washing and protecting product is 0.01-99.9% of the total mass of the medicine or the disinfectant or the washing and protecting product.
The application of the traditional Chinese medicine composition for contracting and tightening vagina is characterized in that the medicine or disinfectant or washing product comprises but is not limited to aqua, gel, emulsion, ointment, tablet, spray, capsule or surfactant system.
The invention provides a traditional Chinese medicine composition for contracting and tightening vagina, which has the following advantages:
1. the traditional Chinese medicine composition for contracting and tightening the vagina provided by the invention selects natural traditional Chinese medicines, is refined, scientifically matched and synergized; has effects of improving vaginal smooth muscle activity, increasing elasticity, repairing injury of intima at private parts, resisting aging of private parts, blackening and tendering, and making private parts remold and compact and recover as the private parts.
2. The traditional Chinese medicine composition for contracting and tightening the vagina provided by the invention is prepared from natural materials, is biodegradable, has no medicine residue, is not easy to generate medicine resistance, is environment-friendly, safe and efficient.
Detailed Description
EXAMPLES 1-4 preparation of a Chinese medicinal composition for tightening vagina
Table 1 shows the specific formulation of the Chinese medicinal composition for tightening vagina in examples 1 to 4.
Table 1 specific formula of traditional Chinese medicine composition for contracting and tightening vagina
Figure BSA0000219341130000021
Preparation methods of a1 to a4 in examples 1 to 4:
(1) cleaning the above Chinese medicinal materials, removing impurities, oven drying at 50 deg.C, and cutting into pieces of about 3cm2Small pieces of (2);
(2) soaking Galla chinensis, pericarpium Granati, fructus Citri Junoris, Corni fructus, fructus bisabolo, flos Caryophylli, radix Aristolochice, fructus Zanthoxyli and fructus Lipuidambaris in 10 times of deionized water for 24 hr, performing ultrasonic extraction at 45 deg.C for 4 hr, filtering, performing ultrasonic extraction on the residue with 6 times of water at 45 deg.C for 4 hr, mixing filtrates of 2 times, and concentrating the filtrates of the Chinese medicinal materials at about 50 deg.C to appropriate volume to obtain Chinese medicinal extractive solutions;
(3) soaking herba Centellae in 8 times of 75% ethanol solution for 24 hr, reflux-extracting at 50 deg.C for 6 hr, filtering, reflux-extracting the residue with 8 times of 75% ethanol solution at 50 deg.C for 6 hr, mixing filtrates, concentrating to remove ethanol, and concentrating to appropriate volume to obtain herba Centellae extract;
(4) weighing proper extracts according to the formulas A1-A4, adding proper propylene glycol and deionized water, and mixing uniformly to obtain the Chinese medicinal composition A1-A4 for contracting and tightening vagina.
Example 5 preparation of a Chinese medicinal composition aqua for contracting and tightening vagina
The composition comprises the following components: formulation A1 in example 1
The preparation method comprises the following steps: adding 0.15 part of EDTA-2Na into 81.04 parts of deionized water, stirring until the EDTA-2Na is completely dissolved, adding 2.8 parts of biological bacteriostatic agent BioMAPAs, 8 parts of propylene glycol and 3.5 parts of PEG-7 which are mixed in advance, uniformly mixing, sequentially adding 3.5 parts of traditional Chinese medicine composition A1 for contracting and tightening the vagina and 0.01 part of menthol dissolved in 1 part of alcohol in advance, uniformly mixing, and adding lactic acid to adjust the pH value to about 4.3, thus preparing the traditional Chinese medicine composition aqua for contracting and tightening the vagina.
Examples 6 to 7 preparation of a gel containing a Chinese medicinal composition for tightening vagina
TABLE 2 gel formulation containing Chinese medicinal composition for tightening vagina
Figure BSA0000219341130000031
The preparation method of the traditional Chinese medicine composition gel containing the vagina for contracting and tightening comprises the following steps:
(1) according to the formula composition of the gel in application examples 6 and 7 and comparative example 1 in the table 2, the components of the phase A are heated to 80-85 ℃, stirred and dissolved completely, kept at the constant temperature for 15min and then cooled to 55 ℃;
(2) mixing and dissolving all the components of the phase B completely, adding the components into the phase A, and stirring and mixing the components uniformly;
(3) then C, D phase components are added in sequence and mixed evenly;
(4) and adding TEA in the phase E, stirring until the mixture is transparent, adding lactic acid, adjusting the pH value to 4.3, cooling to 37 ℃, and discharging. Thus obtaining the vagina contracting bacteriostatic gel I, the vagina contracting bacteriostatic gel II and the basic gel 1.
Examples 8 to 9 preparation of an emulsion containing a Chinese medicinal composition for tightening vagina
TABLE 3 emulsion formula containing Chinese medicinal composition for tightening vagina
Figure BSA0000219341130000041
The preparation method of the traditional Chinese medicine composition milk containing the vagina for contracting and tightening comprises the following steps:
(1) according to the formula composition of the emulsions of application examples 8 and 9 and comparative example 2 in the table 2, heating the phase A components to 85-90 ℃, stirring and dissolving completely, and keeping the temperature for 15 min;
(2) mixing and heating the components of the phase B to 90-95 ℃ to be completely dissolved, and keeping the temperature for 15 min;
(3) adding the phase A component into the phase B while stirring, and homogenizing and mixing at 3000 r/min;
(4) cooling to 55 ℃ under slow stirring, adding the C phase component, and uniformly mixing;
(5) sequentially adding D, E phases of the components, and uniformly mixing;
(6) adding phase F to adjust pH, and stirring to obtain vagina contracting antibacterial milk I, II and basic milk.
Example 10 preparation of an ointment containing a Chinese medicinal composition for tightening vagina
Composition of the composition: formulation a4 in example 4.
The preparation method comprises the following steps: melting 88.5 parts of vaseline at the temperature of 80-100 ℃, sterilizing at the temperature of 115-120 ℃, and cooling the sterilized vaseline to 70-75 ℃; sterilizing lanolin 5 parts at 120 deg.C; 3.5 parts of dimethyl sulfoxide is melted at about 60 ℃; adding vaseline into a preparation tank, and pouring dimethyl sulfoxide and lanolin into the preparation tank for co-melting under stirring; then adding 3 parts of BioMAPAs and the traditional Chinese medicine composition A1 for contracting and tightening vagina into a preparation tank, and uniformly stirring to obtain the vagina-tightening medicine.
Example 11 preparation of a Chinese medicinal composition private lotion for tightening vagina
The composition comprises the following components: formulation A3 in example 3
The preparation method comprises the following steps: completely dissolving 0.15 part of xanthan gum, 1 part of trehalose, 0.1 part of EDTA-2Na and 68.245 parts of deionized water at 75 ℃; adding 11 parts of LS30 and 4.5 parts of AC-203, uniformly stirring, then adding 2.5 parts of BioMAPAs (biological bacteriostatic agents), 6 parts of propylene glycol and 2 parts of PEG-7 which are mixed in advance, uniformly mixing, then adding 3.5 parts of the traditional Chinese medicine composition A3 for contracting and tightening the vagina, then adding 0.005 part of borneol dissolved in 1 part of alcohol in advance, and then adjusting the pH value to about 4.5 by using a proper amount of citric acid, thus preparing the private lotion of the traditional Chinese medicine composition containing the contracting and tightening the vagina.
The beneficial effects of the traditional Chinese medicine composition containing vagina for contracting and tightening are illustrated by specific experimental examples below.
Test objects: 40 cases of women aged 28-60 years
Clinical symptoms: vaginal relaxation
The test method comprises the following steps: before use, cleaning vulva, adopting a supine position, raising buttocks, pushing the vagina-contracting and bacteriostasis gel I prepared in the example 6 into a private depth, 1 piece per night, and keeping supine for 15 min; the application is continued for 7 days. The composition has obvious effect after 5-7 days, can be used after being used for 7 days and having a rest for 2 days, can delay aging after being used for a long time, and is tender in private parts.
The judgment standard of the curative effect is as follows:
the effect is shown: shrink to pre-married standard
The method has the following advantages: has a certain shrinkage, but stops the shrinkage later
And (4) invalidation: is not contracted at all
TABLE 4 vagina-contracting bacteriostasis test
Number of people Percentage of
Show effect 38 95.0%
Is effective 2 5.0%
Invalidation 0 0
Total up to 40 100.0%
The results are shown in Table 4. Clinical test results show that the effective rate of 40 women reaches 100.0% by adopting 4% of the traditional Chinese medicine composition gel for shrinking and tightening vagina, and the vagina is shrunk after each administration. The more the patient is younger, the more the contraction effect is obvious, the effect can be shown after taking the medicine for about 4 days, and the effect can be shown after taking the medicine for 7 days old. After long-term use, the color can be lightened, the menstruation is normal, the phenomenon of excessive leucorrhea and peculiar smell completely disappears, the symptoms such as dry face, dullness and the like disappear, and people also appear to be younger than before. Therefore, the traditional Chinese medicine composition for vagina contraction and tightening has a remarkable vagina contraction effect, can resist aging and recover private elasticity.
The foregoing is a more detailed description of the invention in connection with specific preferred embodiments and it is not intended that the invention be limited to these specific details. For those skilled in the art to which the invention pertains, several simple deductions or substitutions can be made without departing from the spirit of the invention, and all shall be considered as belonging to the protection scope of the invention.

Claims (6)

1. The traditional Chinese medicine composition for contracting and tightening vagina is characterized by comprising the following components in parts by mass: 1-10 parts of gallnut extract, 1-10 parts of pomegranate bark extract, 1-10 parts of lime fruit extract, 1-10 parts of dogwood extract, 1-10 parts of centella asiatica extract, 1-20 parts of propylene glycol and 1-20 parts of deionized water.
2. The traditional Chinese medicine composition for contracting and tightening vagina is characterized by comprising the following components in parts by mass: 1-10 parts of gallnut extract, 1-10 parts of pomegranate bark extract, 1-10 parts of lime fruit extract, 1-10 parts of dogwood extract, 1-10 parts of centella extract, 1-20 parts of propylene glycol, 1-20 parts of deionized water, 1-10 parts of bisabolol extract, 1-10 parts of dutchmanspipe root extract, 1-10 parts of pericarpium zanthoxyli extract, 1-10 parts of clove extract, 1-10 parts of radix angelicae extract and 1-10 parts of fructus liquidambaris extract.
3. The method for preparing the traditional Chinese medicine composition for tightening vagina according to any one of claims 1 and 2, characterized by comprising the following steps:
(1) removing impurities from the raw materials, cleaning, drying at 40-60 deg.C, and cutting into pieces of 2-4 cm2Small pieces of (2);
(2) soaking gallnut, pomegranate rind, orange fruit, dogwood, myrrh, clove, dutchmanspipe root, pericarpium zanthoxyli and sweetgum fruit in 8-10 times of deionized water for 24 hours respectively, then performing ultrasonic extraction at 40-50 ℃ for 4 hours, filtering, performing ultrasonic extraction on filter residues for 4 hours at 40-50 ℃ by using 6-8 times of water, combining filtrates obtained in 2 times, and concentrating the filtrates of the traditional Chinese medicines to proper volumes at about 50 ℃ respectively to obtain traditional Chinese medicine extracting solutions;
(3) soaking centella asiatica in 8-10 times of 70-90% ethanol solution for 24 hours, then performing reflux extraction at 30-60 ℃ for 6 hours, filtering, extracting filter residues with 6-8 times of 70-90% ethanol solution at 30-60 ℃ for 6 hours, combining filtrates, concentrating at 50-60 ℃ to remove ethanol, and concentrating to a proper volume to obtain a centella asiatica extract;
(4) weighing a proper amount of the extract according to a proportion, then adding a proper amount of propylene glycol and deionized water, and uniformly mixing to obtain the traditional Chinese medicine composition for contracting and tightening vagina.
4. The vaginal contraction and tightening traditional Chinese medicine composition as claimed in any one of claims 1 and 2, wherein the application of the traditional Chinese medicine composition in medicines or disinfectants or washing and caring products.
5. The application of the traditional Chinese medicine composition for tightening vagina according to claim 4, wherein the usage amount of the traditional Chinese medicine composition in a medicine or a disinfectant or a washing and protecting product is 0.01-99.9% of the total mass of the medicine or the disinfectant or the washing and protecting product.
6. The use of the vaginal contraction and tightening composition as claimed in any one of claims 4 and 5, wherein the medicine or disinfectant or washing product includes but is not limited to aqua, gel, lotion, ointment, tablet, spray, capsule or topical system.
CN202010958409.XA 2020-09-14 2020-09-14 Traditional Chinese medicine composition for contracting and tightening vagina and preparation method and application thereof Pending CN111888405A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010958409.XA CN111888405A (en) 2020-09-14 2020-09-14 Traditional Chinese medicine composition for contracting and tightening vagina and preparation method and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010958409.XA CN111888405A (en) 2020-09-14 2020-09-14 Traditional Chinese medicine composition for contracting and tightening vagina and preparation method and application thereof

Publications (1)

Publication Number Publication Date
CN111888405A true CN111888405A (en) 2020-11-06

Family

ID=73225210

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010958409.XA Pending CN111888405A (en) 2020-09-14 2020-09-14 Traditional Chinese medicine composition for contracting and tightening vagina and preparation method and application thereof

Country Status (1)

Country Link
CN (1) CN111888405A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1124648A (en) * 1995-06-05 1996-06-19 陈永和 Preparation of Chinese herbal medicine for constricting woman vagina
CN110548078A (en) * 2018-05-31 2019-12-10 张仁维 Composition containing Rutaceae plant extract

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1124648A (en) * 1995-06-05 1996-06-19 陈永和 Preparation of Chinese herbal medicine for constricting woman vagina
CN110548078A (en) * 2018-05-31 2019-12-10 张仁维 Composition containing Rutaceae plant extract

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陈文;等: "响应面优化UAE积雪草中积雪草苷工艺", 《食品工业》 *

Similar Documents

Publication Publication Date Title
CN103446001B (en) Breast beautifying skin and preserving health massage cream and manufacture method thereof
CN105998972A (en) Bacteriostatic gel
CN105125466A (en) Freckle removing night cream and preparing method thereof
CN105213941A (en) A kind of Chinese medicine composition being used for the treatment of infantile diarrhea and preparation method thereof
CN106619780A (en) Gynecological antibacterial gel
CN110339249B (en) Traditional Chinese medicine composition for treating hemorrhoids and anal fissure as well as preparation method and application thereof
CN105055849A (en) Traditional Chinese medicine extract capable of nourishing Yin and tonifying kidney as well as preparation method and application of traditional Chinese medicine extract
CN111658564A (en) Gynecological vulva foam lotion and preparation method thereof
CN110613786A (en) Operation method for female privacy nursing
CN106581246A (en) Traditional Chinese medicine paste for treating hemorrhoids and preparation method thereof
CN107693607B (en) Traditional Chinese medicine composition for preventing and treating cow retained afterbirth and incomplete involution of uterus and preparation method thereof
CN111888405A (en) Traditional Chinese medicine composition for contracting and tightening vagina and preparation method and application thereof
CN109464517A (en) Clearing heat and detoxicating paediatrics external application massage ointment formula, the method and application for preparing ointment
CN109453314A (en) A kind of Chinese medicine composition fumigated for gynaecology's postoperative rehabilitation
CN104740320A (en) Traditional Chinese medicine composition for treating acne and preparation method thereof
CN108938703A (en) The gynecological gel of quick antibacterial
CN109925367A (en) A kind of prevention and treatment hemorrhoid fit perfectly
CN102698086A (en) Chinese medicinal emulsion for treating bedsore accumulated toxin decay
CN106362002A (en) Ointment for treatment of erythrodermic psoriasis and preparation method thereof
CN111184832A (en) Plant probiotic composition with functions of contracting vagina, lubricating, nourishing and protecting nests and preparation method thereof
CN109925426A (en) A kind of herbal fumigation agent can treat hemorrhoid
CN104922449A (en) Traditional Chinese medicine disinfection solution and preparation method thereof
CN105055800A (en) Plant compound gel for treating chloasma and preparation method thereof
CN110974935A (en) Antibacterial nursing gel containing fullerene C60 component and preparation method thereof
CN108272988A (en) Treat Chinese medicine composition, Chinese medicine preparation and the preparation method and application method of eczema

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20201106