CN106362002A - Ointment for treatment of erythrodermic psoriasis and preparation method thereof - Google Patents

Ointment for treatment of erythrodermic psoriasis and preparation method thereof Download PDF

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Publication number
CN106362002A
CN106362002A CN201610865316.6A CN201610865316A CN106362002A CN 106362002 A CN106362002 A CN 106362002A CN 201610865316 A CN201610865316 A CN 201610865316A CN 106362002 A CN106362002 A CN 106362002A
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CN
China
Prior art keywords
ointment
parts
skin
folium mori
vaseline
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Pending
Application number
CN201610865316.6A
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Chinese (zh)
Inventor
马建国
马龙
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Individual
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Individual
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Priority to CN201610865316.6A priority Critical patent/CN106362002A/en
Publication of CN106362002A publication Critical patent/CN106362002A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Abstract

The invention discloses an ointment for treatment of erythrodermic psoriasis and a preparation method thereof. The ointment comprises, by weight, 100-10 parts of radix cynanchi atrati, 100-10 parts of dendrobe, 100-10 parts of bistort rhizome, 100-10 parts of folium mori and 3000-150 parts of petrolatum jelly. The preparation method includes the following steps: firstly heating the petrolatum jelly until melting down, mixing the radix cynanchi atrati, dendrobe, bistort rhizome, and folium mori into the petrolatum jelly and soaking for 6 days, then heating the mixture until the mixture turns into brown, taking out the mixture residue when the temperature is 150-100 DEG C, waiting the medicinal oil cooling and drying to condensate into ointment, packing with plastic case for readily use. The ointment has the advantages of the direct smearing of the ointment on the lesions and has the advantageous effects of removing pathogenic heat from blood, nourishing yin and moisturizing skin and expelling wind and relieving convulsion. Based on the patient's responses after taking the ointment the skin feels comfortable and well nourished. The ointment can soften the scale, make the skin desquamation subside gradually. The ointment has no stimulating effects to the skin and has the function of skin protection.

Description

A kind of treat ointment of erythrodermic psoriasis and preparation method thereof
Technical field
The present invention and a kind of Chinese medicine ointment, specially a kind of ointment treating erythrodermic psoriasis and its preparation side Method.
Background technology
Erythrodermic psoriasis are a kind of common dermatosiss, and the cause of disease is some drugses for oral administration, and most of patients is by urgency Property urticaria, psoriasis vulgariss enter the departure date, allergic dermatitises, acute eczema etc., external intense stimulus dermal drug, such as wind oil Essence, ethanol, povidone iodine, Liushen toilet water, safflower oil, and other is containing Camphora, Borneolum Syntheticum, sulfur, Herba Menthae, salicylic acid, tar class medicine Caused by the external preparation such as thing.Often first there is lamellar erythema at a certain position of body, the whole body can be spread to rapidly within a few days, acute Phase can have the symptoms such as heating general malaise.Whole skin diffuses sexflush, is dried, overlying compared with scaliness, feel micro- itch, skin is felt There is tight feeling.
The traditional Chinese medical science thinks, primary disease is that skin has heat, and external irritant in addition injures cloudy blood dryness-transformation, and skin loses its profit and supports, and is in dry Dry squama comes off.
This disease of conventional therapy, doctor trained in Western medicine corticosteroid hormone such as prednisone, dexamethasone take orally, several hormoness of external Cream, such as Pevisone, Eloson, Halcinonide cream, fluocinolone acetonide ointment are put on the skin in affected part.
This disease of Chinese traditional treatment, with blood-nourishing skin-moisturizing, wind-dispelling stops ancient term for country school Chinese medicine clothes, but many patients think, the bitter in the mouth that takes traditional Chinese medicine shows Imitate relatively slowly it is difficult to adhere to taking, external hormone medicine, causes apparent side effect to body skin.Therefore still weary one kind so far Treatment erythrodermic psoriasis, can make skin lesion gradually disappear, and simple and easy to do external application Chinese medicine unguentum.
Content of the invention
The object of the invention, is dried to release erythrodermic psoriasis patient's skin flushing, and hot desquamation of itching is painful, by the traditional Chinese medical science Theoretical point view, preferably develops a kind of clearing away heat from blood Glycerin, puts on the skin outside antipruritic Chinese medicinal ointment.
The present invention is achieved in that a kind of ointment treating erythrodermic psoriasis, and it is by following weight proportioning Raw material make: 100 1 10 parts of Radix Cynanchi Atrati, 100 1 10 parts of Herba Dendrobii, 100 1 10 parts of Rhizoma Bistortae, 100 1 10 parts of Folium Mori, vaseline 3000 One 150 parts.
Specifically, best weight ratio scope is: 10 parts of Radix Cynanchi Atrati, 10 parts of Herba Dendrobii, 10 parts of Rhizoma Bistortae, 10 parts of Folium Mori, vaseline 150 parts.
The preparation method of ointment of the present invention is: first vaseline heating melted, by Radix Cynanchi Atrati, Herba Dendrobii, Rhizoma Bistortae, Folium Mori, Enter in vaseline and soak 6 days, then heat and explode medicine to brown, during 150 1 100 DEG C of temperature, pull medicinal residues out, medicine oil cool solidifying after Paste, standby in subpackage plastic casing.
The medication of the present invention is according to being: Radix Cynanchi Atrati, bitter in the mouth, salty, cold in nature.Oily, its fall cool in nature containing Radix Cynanchi Atrati, can clearing away heat from blood;Herba Dendrobii, Sweet in the mouth, cold in nature.Modern study, mucus containing volume, is that nourishing YIN and clearing away heat commonly uses key medicine, " book on Chinese herbal medicine is just read ": " by skin pathogenic heat ".Clinical Test it, take its external treatment, skin is had good nourishing YIN and clearing away heat moisturize effect;Rhizoma Bistortae, bitter in the mouth, acid, cold nature.Hardship can drop lets out, and acid is then Convergence, trembling with fear can clearing away heat and cooling blood;Folium Mori, bitter in the mouth, sweet, cold in nature.Gently dissipate clearly, sweet cold clear and rich.Can clearing away heat and cooling blood dispelling wind for relieving itching." this Grass is through dredging ": " sweet so beneficial blood, tremble with fear so removing heat from blood "." Bencao Congxin ": " growing dry removing heat from blood ".Vaseline, as substrate, is processed into After ointment, drug effect is all in it.
The invention has the beneficial effects as follows: this medicinal ointment therapy erythrodermic psoriasis, selected medicine is all to take its new use external treatment, Maximum feature is to be applied directly to diseased region, plays clearing away heat and cooling blood, YIN nourishing skin moistening, the good effect of dispelling wind for relieving itching.According to clinical observation and Patient's reaction, after putting this ointment on the skin, skin is all felt comfortable and is moistened, and can soften squama, so that dry desquamative skin lesion is gradually able to Disappear, to skin nothing else zest, and have protection skin effect.Without medication, easy to use, with other external used medicine phases Ratio really has certain superiority and practicality.During advising patient's treatment or a rear period, reduce and have a bath number of times, do not eat raw meat peppery Thing, polyphagia fresh vegetabless fruit, drink more water, comparatively fast disappeared with sharp skin lesion.
The using method of ointment: applied with cream plate and put on the skin at skin lesion, day 2 one 3 times, all disappear to erythra, gargalesthesia is dried and disappears, Skin recovers normal.
Clinical observation on the therapeutic effect: clinical treatment 143, man 92, female 51, at 25 1 74 years old age, all cases all meet Erythrodermic psoriasis diagnostic criteria.
Efficacy evaluation: with reference to traditional Chinese medical science erythrodermic psoriasis Standardization of diagnosis and curative effect, recovery from illness: skin lesion disappears completely.Take a turn for the better: skin Damage disappears more than 50%.Do not heal: skin lesion disappears less than 30%.All after treating 30 days, carry out curative effect statistics.
Therapeutic outcome: recovery from illness 127, takes a turn for the better 16.
Specific embodiment
The technical characteristic of the present invention is described with specific embodiment below.
Embodiment 1: Radix Cynanchi Atrati 10g, Herba Dendrobii 10g, Rhizoma Bistortae 10g, Folium Mori 10, vaseline 150g.
The preparation process of this ointment is: first melts vaseline heating, Radix Cynanchi Atrati, Herba Dendrobii, Rhizoma Bistortae, Folium Mori enter vaseline Middle soak 6 days, medicine heating is exploded to filbert, during temperature 150 1 100c, pulls medicinal residues out, medicine oil cool solidifying after cream Shape, in subpackage plastic casing.
Embodiment 2: Radix Cynanchi Atrati 30g, Herba Dendrobii 30g, Rhizoma Bistortae 30g, Folium Mori 30g, vaseline 900g.
Embodiment 3: Radix Cynanchi Atrati 60g, Herba Dendrobii 60g, Rhizoma Bistortae 60g, Folium Mori 60g, vaseline 2300g.
The preparation process of this medicine oil, is processed by the preparation technology of above-described embodiment 1.
From practice, comparitive study is carried out to 3 embodiment schemes it is believed that embodiment 1 curative effect is better than embodiment 2, implements Example 3, so embodiment 1 is most preferred embodiment.

Claims (3)

1. a kind of ointment treating erythrodermic psoriasis is it is characterised in that it is made up of the raw material of following weight proportioning: white 100 1 10 parts of common vetch, 100 1 10 parts of Herba Dendrobii, 100 1 10 parts of Rhizoma Bistortae, 100 1 10 parts of Folium Mori, 3,000 1 150 parts of vaseline.
2. the ointment for the treatment of erythrodermic psoriasis as claimed in claim 1 is it is characterised in that it is by following weight proportioning Raw material make: 10 parts of Radix Cynanchi Atrati, 10 parts of Herba Dendrobii, 10 parts of Rhizoma Bistortae, 10 parts of Folium Mori, 150 parts of vaseline.
3. a kind of ointment preparation method treating erythrodermic psoriasis is it is characterised in that comprise the steps: first by vaseline Heating melts, and Radix Cynanchi Atrati, Herba Dendrobii, Rhizoma Bistortae, Folium Mori enter in vaseline and soak 6 days, then heat and explode medicine to brown, temperature 150 When one 100 DEG C, pull medicinal residues out, medicine oil cool solidifying after paste, standby in Split charging box.
CN201610865316.6A 2016-09-30 2016-09-30 Ointment for treatment of erythrodermic psoriasis and preparation method thereof Pending CN106362002A (en)

Priority Applications (1)

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CN201610865316.6A CN106362002A (en) 2016-09-30 2016-09-30 Ointment for treatment of erythrodermic psoriasis and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610865316.6A CN106362002A (en) 2016-09-30 2016-09-30 Ointment for treatment of erythrodermic psoriasis and preparation method thereof

Publications (1)

Publication Number Publication Date
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823513A (en) * 2017-12-28 2018-03-23 马建国 A kind of ointment for treating knuckle pad and preparation method thereof
CN107929532A (en) * 2017-12-05 2018-04-20 马建国 A kind of ointment of the company's for the treatment of round chaff rash and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1315202A (en) * 2000-03-24 2001-10-03 张世刚 Ointment for treating psoriasis
CN103784641A (en) * 2014-02-08 2014-05-14 张孝昌 Traditional Chinese medicine for treating psoriasis
CN105663464A (en) * 2016-01-21 2016-06-15 任同亮 Formula for treating psoriasis and preparation method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1315202A (en) * 2000-03-24 2001-10-03 张世刚 Ointment for treating psoriasis
CN103784641A (en) * 2014-02-08 2014-05-14 张孝昌 Traditional Chinese medicine for treating psoriasis
CN105663464A (en) * 2016-01-21 2016-06-15 任同亮 Formula for treating psoriasis and preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘洪普等: "《实用基层医生皮肤性病科诊疗手册》", 31 October 2010, 郑州大学出版社 *
刘绍贵等: "《临床常用中草药鉴别与应用》", 31 July 2015, 湖南科学技术出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929532A (en) * 2017-12-05 2018-04-20 马建国 A kind of ointment of the company's for the treatment of round chaff rash and preparation method thereof
CN107823513A (en) * 2017-12-28 2018-03-23 马建国 A kind of ointment for treating knuckle pad and preparation method thereof

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Application publication date: 20170201

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