CN111840187A - Herbal repairing and antiallergic composition, mask and preparation method thereof - Google Patents
Herbal repairing and antiallergic composition, mask and preparation method thereof Download PDFInfo
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- CN111840187A CN111840187A CN202010903872.4A CN202010903872A CN111840187A CN 111840187 A CN111840187 A CN 111840187A CN 202010903872 A CN202010903872 A CN 202010903872A CN 111840187 A CN111840187 A CN 111840187A
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- extract
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- mask
- repairing
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Abstract
The invention provides a herbal repair antiallergic composition, a mask and a preparation method thereof; the herbal repair antiallergic composition comprises the following components: 0.03-1.5 parts by weight of cistanche extract; 0.02-1 part by weight of crocus sativus extract; 0.02-1 part by weight of industrial hemp leaf extract; 0.02-1 part by weight of a salvia miltiorrhiza extract; 0.01-0.5 parts by weight of centella asiatica extract. Compared with the prior art, the five traditional Chinese medicine components of the cistanche extract, the crocus sativus extract, the industrial hemp leaf extract, the salvia miltiorrhiza extract and the centella asiatica extract are compounded according to a certain proportion, mutually supplemented and synergized, so that the obtained herbal repairing and antiallergic composition has excellent repairing and antiallergic effects, and can achieve the effects of relieving and calming, diminishing inflammation and repairing skin barriers; meanwhile, the essence added with the herbal repairing and antiallergic composition is matched with a specific mask base cloth, so that the mask is better in use feeling and efficacy.
Description
Technical Field
The invention relates to the technical field of daily chemical products, in particular to a herbal repairing and anti-allergy composition, a mask and a preparation method thereof.
Background
Allergic disease (also known as allergic disease) has become a global epidemic, not just a common disease. The causes of allergic diseases have not been determined at present, for example, the gradual deterioration of the living environment and the accelerated industrialization process and the aggravation of air pollution cause that many people who are not allergic in nature also gradually become allergic in nature. With the increase of vehicles, the aromatic hydrocarbon particles in the automobile exhaust gas accelerate the allergic inflammation reaction. In addition, chemical gases such as formaldehyde brought by home decoration are also factors causing allergy. In addition, the increase of dietary calorie and fat content causes the increase of free radicals of human body, and is also one of the causes of allergic and inflammatory reactions of the body.
Generally, allergic reactions can cause allergic symptoms such as pruritus, red swelling, rash, pox, stabbing pain, flushing, red blood streak and the like. Is very bad for the health of human body and seriously affects the life of people. Some people can relieve symptoms by taking antiallergic drugs, but the antiallergic drugs have side effects, and long-term and large-dose taking of a certain antiallergic drug is not suitable, so that the antiallergic drugs are easy to lose effectiveness, and serious people can have various adverse reactions and even toxic and side effects. Certainly, plant antiallergic components exist in the market, but the really effective components are relatively few, the components are mainly concentrated on aloe, chamomile, liquorice, purslane and rhodiola rosea, more components are concentrated on skin repair and maintenance, and the research on the addition amount and the optimal compatibility is less.
With the improvement of national economic level, cosmetics become necessities of daily life of people, and the proportion of the cost spent on the cosmetics by people is gradually increased. The allergic reaction caused by the use of cosmetics is also increasing, and the safety of cosmetics is more and more important. Meanwhile, the number of the facial masks added with the plant antiallergic components is also large, but most of the research objects are facial mask essence, and the interaction between the facial mask essence and the base cloth of the carrier facial mask is not considered. In fact, factors such as adsorption capacity, air permeability and affinity of the mask base cloth have an important influence on the use feeling and the efficacy of the mask essence.
Disclosure of Invention
In view of the above, the present invention aims to provide a herbal repairing and antiallergic composition, a mask and a preparation method thereof, and the herbal repairing and antiallergic composition provided by the invention has excellent repairing and antiallergic effects, and can achieve the effects of soothing and calming, diminishing inflammation and repairing skin barriers; meanwhile, the essence added with the herbal repairing and antiallergic composition is matched with a specific mask base cloth, so that the mask is better in use feeling and efficacy.
The invention provides a herbal repair anti-allergic composition, which comprises the following components:
0.03-1.5 parts by weight of cistanche extract;
0.02-1 part by weight of crocus sativus extract;
0.02-1 part by weight of industrial hemp leaf extract;
0.02-1 part by weight of a salvia miltiorrhiza extract;
0.01-0.5 parts by weight of centella asiatica extract.
The invention also provides a herbal repair anti-allergy mask which consists of essence and mask base cloth;
the essence is prepared from the following raw materials:
71.622-94.56 parts by weight of a solvent;
0-11.75 parts by weight of a humectant;
0-1 part by weight of a solubilizer;
0.1-5 parts by weight of herbal repair antiallergic composition;
0.22-13.678 parts by weight of a skin conditioner;
0.1-0.8 parts of thickening agent;
0.02-0.1 part by weight of a chelating agent;
0-0.05 parts by weight of an aromatic;
0.1-0.6 parts by weight of a preservative;
0-0.3 part of pH regulator;
the herbal repairing antiallergic composition is the herbal repairing antiallergic composition in the technical scheme;
the facial mask base cloth is made of cuprammonium fibers, hydrogel, pure cotton fibers, biological fibers, viscose fibers, wormwood fibers or bamboo charcoal fibers.
Preferably, the humectant is selected from one or more of glycerin, sodium hyaluronate, trehalose, hydrolyzed sodium hyaluronate, hydroxyethyl urea, and glyceryl polyether-26.
Preferably, the solubilizer is selected from one or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, PPG-26-butanol polyether and Tween-20.
Preferably, the skin conditioning agent is selected from one or more of niacinamide, ascorbyl glucoside, allantoin, sea buckthorn extract, marshmallow root extract, nutmeg extract, purslane extract, BPN-meso 1600solution, carnosine, dipeptide diaminobutyrobenzyl amide diacetate, Prolevis, dipotassium glycyrrhizinate, sodium metabisulfite, arginine, ethylhexylglycerin, p-hydroxyacetophenone, dextrin, and polyethylene glycol-8.
Preferably, the thickening agent is selected from one or more of carbomer, polyacrylic acid, xanthan gum, acrylic acid or acrylate/C10-30 alkanol acrylate cross-linked polymer and hydroxyethyl cellulose;
preferably, the chelating agent is selected from disodium EDTA, trisodium EDTA or tetrasodium EDTA.
Preferably, the preservative is selected from one or more of phenoxyethanol, potassium sorbate and sodium benzoate.
Preferably, the pH adjusting agent is selected from citric acid and/or sodium citrate.
The invention also provides a preparation method of the herbal repairing antiallergic mask, which comprises the following steps:
a) uniformly mixing a solvent, a humectant, a solubilizer, a skin conditioner, a thickening agent, a chelating agent, an aromatic and a pH regulator in a vacuum emulsification tank; adding herbal repairing antiallergic composition and antiseptic, and dispersing; then cooling to 32-35 ℃, defoaming, filtering and discharging to obtain essence;
b) filling the essence obtained in the step a) and mask base cloth together to obtain the herbal repairing anti-allergic mask.
The invention provides a herbal repair antiallergic composition, a mask and a preparation method thereof; the grass repair antiallergic composition comprises the following components: 0.03-1.5 parts by weight of cistanche extract; 0.02-1 part by weight of crocus sativus extract; 0.02-1 part by weight of industrial hemp leaf extract; 0.02-1 part by weight of a salvia miltiorrhiza extract; 0.01-0.5 parts by weight of centella asiatica extract. Compared with the prior art, the five traditional Chinese medicine components of the cistanche extract, the crocus sativus extract, the industrial hemp leaf extract, the salvia miltiorrhiza extract and the centella asiatica extract are compounded according to a certain proportion, mutually supplemented and synergized, and the obtained herbal repairing and antiallergic composition has excellent repairing and antiallergic effects and can achieve the effects of relieving and calming the nerves, diminishing inflammation and repairing skin barriers; meanwhile, the essence added with the herbal repairing and antiallergic composition is matched with a specific mask base cloth, so that the use feeling and the efficacy are better.
In addition, the preparation method provided by the invention has the advantages of simple process, mild conditions, easiness in operation control, suitability for large-scale production and wide application prospect.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides a herbal repair anti-allergic composition, which comprises the following components:
0.03-1.5 parts by weight of cistanche extract;
0.02-1 part by weight of crocus sativus extract;
0.02-1 part by weight of industrial hemp leaf extract;
0.02-1 part by weight of a salvia miltiorrhiza extract;
0.01-0.5 parts by weight of centella asiatica extract.
In the present invention, the herbal repair antiallergic composition comprises, preferably consists of, cistanche extract, crocus extract, industrial cannabis leaf extract, salviae miltiorrhizae extract and centella asiatica extract. The sources of the cistanche extract, the crocus sativus extract, the industrial cannabis leaf extract, the salvia miltiorrhiza extract and the centella asiatica extract are not particularly limited, and commercially available products well known to those skilled in the art can be adopted.
In the present invention, the content of the effective components in the cistanche salsa extract is preferably: the content of phenylethanoid glycosides is not less than 20%. Phenylethanoid glycosides are the main effective components of Cistanchis herba; the phenylethanoid glycoside is a natural antioxidant, has obvious antioxidant effect in vitro, and can scavenge various free radicals such as superoxide radical, hydroxyl radical and the like. Meanwhile, the skin care product has excellent anti-inflammatory and relieving effects, and can promote the proliferation of fibroblasts, thereby endogenously promoting the repair of skin barriers. In the present invention, the herbal repairing antiallergic composition comprises 0.03 to 1.5 parts by weight of cistanche salsa extract, preferably 0.05 to 1.5 parts by weight, and more preferably 0.3 part by weight.
In the present invention, the content of the effective components in the crocus sativus extract is preferably: the content of crocetin is more than or equal to 10 percent. The crocetin is the main active component of crocus, has the effects of resisting inflammation, improving skin microcirculation, and promoting the expression of filaggrin, thereby enhancing the skin barrier function and the synthesis of natural skin moisturizing factors. In the present invention, the herbal repair antiallergic composition comprises 0.02 to 1 part by weight of crocus sativus extract, preferably 0.04 to 1 part by weight, and more preferably 0.2 part by weight.
In the present invention, the content of the effective components in the industrial cannabis leaf extract is preferably: the content of cannabidiol is more than or equal to 5 percent. Cannabidiol (CBD) is a main chemical component in medicinal plant industrial cannabis sativa, is derived from industrial cannabis sativa leaf extract, is a non-addictive component in industrial cannabis sativa, has high anti-inflammatory effect, and can improve skin inflammatory symptoms such as acne, eczema and psoriasis. In the present invention, the herbal remedy antiallergic composition comprises 0.01 to 0.5 parts by weight of the extract of industrial hemp leaves, preferably 0.05 to 0.5 parts by weight, more preferably 0.1 parts by weight.
In the present invention, the content of the effective components in the salvia miltiorrhiza extract is preferably: the content of salvianolic acid is more than or equal to 10 percent. The salvianolic acid is the main active component in the salvia miltiorrhiza, is also the main active component of the salvia miltiorrhiza with the functions of promoting blood circulation and removing blood stasis, and has the functions of improving microcirculation, resisting lipid peroxidation, eliminating free radicals and resisting inflammation. In the invention, the herbal repairing and antiallergic composition comprises 0.02-1 part by weight of the salvia miltiorrhiza extract, preferably 0.06-1 part by weight, and more preferably 0.2 part by weight.
In the present invention, the content of the effective components in the centella asiatica extract is preferably: the asiaticoside content is not less than 8%. Asiaticoside is the main active component in herba Centellae, and has effects of preventing and treating fibroblast generation and collagen synthesis in hypertrophic scar formation process, promoting normal skin collagen synthesis, promoting wound healing and inhibiting inflammation. In the invention, the herbal repairing antiallergic composition comprises 0.02-1 part by weight of centella asiatica extract, preferably 0.06-1 part by weight, and more preferably 0.2 part by weight.
The five traditional Chinese medicine components of the cistanche deserticola extract, the crocus sativus extract, the industrial hemp leaf extract, the salvia miltiorrhiza extract and the centella asiatica extract are compounded according to a certain proportion, are mutually supplemented and synergized, and the obtained herbal repairing and antiallergic composition has excellent repairing and antiallergic effects and can achieve the effects of relieving, calming, diminishing inflammation and repairing skin barriers.
The invention also provides a herbal repair anti-allergy mask which consists of essence and mask base cloth;
the essence is prepared from the following raw materials:
71.622-94.56 parts by weight of a solvent;
0-11.75 parts by weight of a humectant;
0-1 part by weight of a solubilizer;
0.1-5 parts by weight of herbal repair antiallergic composition;
0.22-13.678 parts by weight of a skin conditioner;
0.1-0.8 parts of thickening agent;
0.02-0.1 part by weight of a chelating agent;
0-0.05 parts by weight of an aromatic;
0.1-0.6 parts by weight of a preservative;
0-0.3 part of pH regulator;
the herbal repairing antiallergic composition is the herbal repairing antiallergic composition in the technical scheme;
the facial mask base cloth is made of cuprammonium fibers, hydrogel, pure cotton fibers, biological fibers, viscose fibers, wormwood fibers or bamboo charcoal fibers.
In the present invention, the essence comprises a solvent, a humectant, a solubilizer, a herbal repair antiallergic composition, a skin conditioner, a thickener, a chelating agent, a fragrance, a preservative, and a pH adjuster, and preferably consists of a solvent, a humectant, a solubilizer, a herbal repair antiallergic composition, a skin conditioner, a thickener, a chelating agent, a fragrance, a preservative, and a pH adjuster.
In the present invention, the solvent includes one or more of water, butanediol, 1, 2-hexanediol, 1, 2-pentanediol, and 1, 3-propanediol, and more preferably one or more of water, butanediol, 1, 2-pentanediol, and 1, 3-propanediol. The source of the solvent is not particularly limited in the present invention, and commercially available products of the above-mentioned butanediol, 1, 2-hexanediol, 1, 2-pentanediol and 1, 3-propanediol known to those skilled in the art may be used; the water may be deionized water as is well known to those skilled in the art. In the invention, the solvent is used to ensure that other components can be dissolved, dispersed and uniformly mixed.
In the present invention, the humectant is preferably selected from one or more of glycerin, sodium hyaluronate, trehalose, hydrolyzed sodium hyaluronate, hydroxyethyl urea, and glyceryl polyether-26. The source of the moisturizer is not particularly limited in the present invention, and commercially available products of the above glycerin, sodium hyaluronate, trehalose, hydrolyzed sodium hyaluronate, hydroxyethyl urea and glyceryl polyether-26, which are well known to those skilled in the art, may be used.
In the present invention, the solubilizer is preferably one or more selected from the group consisting of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, PPG-26-butoxypolyether and Tween-20, and more preferably PEG-40 hydrogenated castor oil.
In the invention, the herbal repairing antiallergic composition is the herbal repairing antiallergic composition according to the technical scheme. In the invention, the essence comprises 0.1-5 parts by weight of the herbal repairing anti-allergy composition, and preferably 1-5 parts by weight.
In the present invention, the skin conditioning agent is preferably selected from the group consisting of niacinamide, ascorbyl glucoside, allantoin, sea buckthorn extract, marshmallow root extract, nutmeg extract, purslane extract, BPN-tesoro1600solution (formulation specific: palmitoyl tetrapeptide-7/palmitoyl pentapeptide-4/acetyl hexapeptide-8/water/polysorbate-20/1, 2-hexanediol/glycerin/carbomer), carnosine, dipeptide diaminobutyrobenzylamide diacetate, Prolevis (formulation specific: water/hydrolyzed vegetable protein/phenoxyethanol/sodium benzoate/potassium sorbate/ethylhexylglycerin), dipotassium glycyrrhizinate, sodium metabisulfite, arginine, ethylhexylglycerin, p-hydroxyacetophenone, p-hydroxy acetophenone, and, One or more of dextrin and polyethylene glycol-8, more preferably nicotinamide, ascorbyl glucoside, allantoin, sea buckthorn extract, Althea officinalis root extract, Myristica fragrans extract, Portulaca oleracea extract, BPN-tetrapeptide-7/palmitoyl pentapeptide-4/acetyl hexapeptide-8/water/polysorbate-20/1, 2-hexanediol/glycerol/carbomer), carnosine, dipeptide diaminobutyrylbenzylamide diacetate, Prolevis (water/hydrolyzed vegetable protein/phenoxyethanol/sodium benzoate/potassium sorbate/ethylhexylglycerin), dipotassium glycyrrhizinate, sodium metabisulfite, arginine, p-hydroxyacetophenone, dextrin and polyethylene glycol-8. The source of the skin conditioner of the present invention is not particularly limited, and the above-mentioned niacinamide, ascorbyl glucoside, allantoin, seabuckthorn extract, marshmallow root extract, nutmeg extract, purslane extract, BPN-meso 1600 solubilization (palmitoyl tetrapeptide-7/palmitoyl pentapeptide-4/acetyl hexapeptide-8/water/polysorbate-20/1, 2-hexanediol/glycerin/carbomer), carnosine, dipeptide diaminobutyrobenzylamide diacetate, prolivis (water/hydrolyzed vegetable protein/phenoxyethanol/sodium benzoate/potassium sorbate/ethylhexylglycerin), dipotassium glycyrrhizinate, sodium metabisulfite, arginine, ethylhexylglycerin, p-hydroxyacetophenone, p-hydroxy-phenyl ketone, and the like, well known to those skilled in the art, can be used, Dextrin and polyethylene glycol-8 are commercially available.
In the present invention, the thickener is preferably selected from one or more of carbomer, polyacrylic acid, xanthan gum, acrylic acid or acrylate/C10-30 alkanol acrylate crosspolymer, hydroxyethyl cellulose, more preferably one or more of polyacrylic acid, xanthan gum, acrylic acid or acrylate/C10-30 alkanol acrylate crosspolymer, hydroxyethyl cellulose; wherein the acrylic acid or acrylate/C10-30 alkanol acrylate cross-linked polymer is acrylic acid/C10-30 alkanol acrylate cross-linked polymer which is well known to those skilled in the art. The source of the thickener in the present invention is not particularly limited, and commercially available carbomers, polyacrylic acid, xanthan gum, acrylic acid or acrylic esters/C10-30 alkanol acrylate crosspolymer, hydroxyethyl cellulose, as described above, which are well known to those skilled in the art, may be used.
In the present invention, the chelating agent is preferably selected from disodium EDTA, trisodium EDTA or tetrasodium EDTA, more preferably disodium EDTA. The source of the chelating agent is not particularly limited in the present invention, and commercially available products of the above disodium EDTA, trisodium EDTA, and tetrasodium EDTA, which are well known to those skilled in the art, may be used.
In the present invention, the fragrance is preferably a perfume; the present invention is not particularly limited in its kind and origin.
In the present invention, the preservative is preferably selected from one or more of phenoxyethanol, potassium sorbate and sodium benzoate, more preferably phenoxyethanol. The source of the preservative is not particularly limited in the present invention, and commercially available products of the aforementioned phenoxyethanol, potassium sorbate and sodium benzoate, which are well known to those skilled in the art, may be used.
In the present invention, the pH adjusting agent is preferably selected from citric acid and/or sodium citrate, more preferably citric acid and sodium citrate. The source of the pH regulator in the present invention is not particularly limited, and commercially available products of the above citric acid and sodium citrate, which are well known to those skilled in the art, may be used.
In the invention, the mask base cloth is copper ammonia fiber, hydrogel, pure cotton fiber, biological fiber, viscose fiber, wormwood fiber or bamboo charcoal fiber, preferably wormwood fiber. The source of the mask base cloth is not particularly limited, and commercially available products of the copper ammonia fiber, hydrogel, pure cotton fiber, biological fiber, viscose fiber, wormwood fiber and bamboo charcoal fiber, which are well known to those skilled in the art, can be used.
The copper ammonia fiber is a regenerated cellulose fiber, natural cellulose raw materials such as cotton linters and the like are dissolved in a concentrated ammonia solution of copper hydroxide or alkaline copper salt to prepare spinning solution, the chemical compound of the copper ammonia cellulose molecules is decomposed in a coagulation bath to regenerate cellulose, the generated hydrated cellulose is processed to obtain the copper ammonia fiber, the dry strength of the copper ammonia fiber is close to that of viscose fiber, but the wet strength is higher than that of the viscose fiber, the wear resistance is also superior to that of the viscose fiber, and the copper ammonia fiber has the characteristics of fine and soft fiber, proper luster, good hygroscopicity and performance similar to silk.
In the invention, the hydrogel takes hydrophilic gel as a mask matrix, and is rich in a large amount of nutrients and moisture required by the skin; when the hydrogel facial mask is attached to the skin, the nutritional ingredients contained in the facial mask gradually permeate into the skin, and the skin is not stimulated.
In the invention, the pure cotton fiber is made of 100 percent pure natural cellulose, and the spunlace nonwoven fabric structure is made by a cross lapping method, so that the pure cotton fiber has the characteristics of difficult deformation after water absorption, strong longitudinal and transverse tension, white and soft property, good skin-sticking property and the like; the pure cotton cloth film is thickened and encrypted, has strong water absorption capacity, can absorb high-concentration nutrient substances and can effectively prevent the evaporation and the loss of nutrient components.
In the invention, the biological fiber is microbial cellulose generated by natural fermentation of acetobacter xylinum, has excellent water retention capacity, good biocompatibility and no stimulation; the biological fiber has the function similar to skin, the fiber diameter is 50-80 nm, and the biological fiber can penetrate into skin gully repair cells and tightly hold the skin cells to generate an upward pulling effect.
In the invention, the viscose fiber is cellulose fiber produced by using cotton or other natural fibers as raw materials, has the moisture content meeting the physiological requirements of human skin, and has the characteristics of smoothness, coolness, air permeability, antistatic property and the like.
In the invention, the bamboo charcoal fiber is prepared by taking moso bamboo as a raw material, adopting a new calcining process and a new technology of pure oxygen high temperature and nitrogen blocking time delay to enable micropores of the natural bamboo charcoal to be more refined and honeycombed, and then carrying out melt spinning with a polyester modified slice with a honeycomb micropore structure trend; the unique fiber structure enables the bamboo charcoal fiber mask to have good moisture absorption, air permeability and bacteriostatic effects.
In the invention, the wormwood fiber takes tencel fiber as a carrier, and is complexed with natural wormwood herb extract, so that the wormwood herb fiber has strong moisture absorption performance and good skin adhesion.
The facial mask provided by the invention adopts the essence added with the herbal repairing and antiallergic composition, and is matched with the specific facial mask base cloth, so that the use feeling and the efficacy are better.
The invention also provides a preparation method of the herbal repairing antiallergic mask, which comprises the following steps:
a) uniformly mixing a solvent, a humectant, a solubilizer, a skin conditioner, a thickening agent, a chelating agent, an aromatic and a pH regulator in a vacuum emulsification tank; adding herbal repairing antiallergic composition and antiseptic, and dispersing; then cooling to 32-35 ℃, defoaming, filtering and discharging to obtain essence;
b) filling the essence obtained in the step a) and mask base cloth together to obtain the herbal repairing anti-allergic mask.
The invention firstly mixes solvent, humectant, solubilizer, skin conditioner, thickener, chelating agent, aromatic and pH regulator evenly in a vacuum emulsification tank. In the present invention, the solvent, the moisturizing agent, the solubilizer, the skin conditioner, the thickener, the chelating agent, the fragrance, and the pH adjuster are the same as those described in the above technical solution, and are not described herein again.
The invention carries out the mixing process according to the solubility between the specific components of the humectant, the solubilizer, the skin conditioner, the thickener, the chelating agent, the aromatic and the pH regulator and different solvents; preferably specifically
a1) Putting water, glycerol, sodium hyaluronate, hydrolyzed sodium hyaluronate, hydroxyethyl urea, trehalose, glyceryl polyether-26, allantoin, p-hydroxyacetophenone, carbomer, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, xanthan gum, polyacrylic acid, hydroxyethyl cellulose, EDTA disodium, EDTA trisodium and EDTA tetrasodium into a vacuum emulsification tank, dissolving at 80-85 ℃, uniformly stirring, and cooling to 43-47 ℃ to obtain phase A;
a2) completely dissolving arginine, citric acid and sodium citrate with a part of water in a separate dissolving tank to obtain a phase B;
a3) completely dissolving butanediol, 1, 2-hexanediol, 1, 2-pentanediol, 1, 3-propanediol, essence, PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, PPG-26-butanol polyether, and Tween-20 in a separate dissolving tank to obtain phase C;
a4) adding the phase B and the phase C into a vacuum emulsification tank (phase A) in sequence, and uniformly dispersing.
Then, adding the herbal repairing antiallergic composition and the preservative to disperse uniformly; then cooling to 32-35 ℃, defoaming, filtering and discharging to obtain the essence. In the present invention, the herbal repair antiallergic composition and the antiseptic are the same as those described in the above technical solution, and are not described herein again.
After the essence is obtained, the essence and the mask base cloth are filled together to obtain the herbal repairing anti-allergy mask. In the invention, the mask base cloth is the same as that in the technical scheme, and is not described again.
The preparation method provided by the invention has the advantages of simple process, mild conditions, easiness in operation control, suitability for large-scale production and wide application prospect.
The invention provides a herbal repair antiallergic composition, a mask and a preparation method thereof; the grass repair antiallergic composition comprises the following components: 0.03-1.5 parts by weight of cistanche extract; 0.02-1 part by weight of crocus sativus extract; 0.02-1 part by weight of industrial hemp leaf extract; 0.02-1 part by weight of a salvia miltiorrhiza extract; 0.01-0.5 parts by weight of centella asiatica extract. Compared with the prior art, the five traditional Chinese medicine components of the cistanche extract, the crocus extract, the industrial hemp leaf extract, the salvia extract and the centella extract are compounded according to a certain proportion, mutually supplemented and synergized, and the obtained herbal repairing and antiallergic composition has excellent repairing and antiallergic effects, can achieve the effects of relieving and calming, diminishing inflammation and repairing skins
In addition, the preparation method provided by the invention has the advantages of simple process, mild conditions, easiness in operation control, suitability for large-scale production and wide application prospect.
To further illustrate the present invention, the following examples are provided for illustration. The raw materials used in the following examples of the present invention are all commercially available products; wherein:
cistanche deserticola extract: commercial product, content of effective substances: the content of phenylethanoid glycosides is not less than 20%.
The crocus sativus extract: commercial product, content of effective substances: the content of crocetin is more than or equal to 10 percent.
Industrial cannabis leaf extract: commercial product, content of effective substances: the content of cannabidiol is more than or equal to 5 percent.
The red sage root extract: commercial product, content of effective substances: the content of salvianolic acid is more than or equal to 10 percent.
Centella asiatica extract: commercial product, content of effective substances: the asiaticoside content is not less than 8%.
Example 1: the herbal repair anti-allergic composition
(1) Formulations 1 to 8
TABLE 1 formulary of herbal remedial antiallergic composition of example 1
(2) Comparative examples 1 to 6
Comparative example 1: compared with the formula 3, the traditional Chinese medicine composition does not contain cistanche salsa extract, and the rest is unchanged;
comparative example 2: compared with the formula 3, the traditional Chinese medicine composition does not contain the cistanche extract and the crocus extract, and the rest is unchanged;
comparative example 3: compared with the formula 3, the composition does not contain cistanche extract, crocus sativus extract and industrial hemp leaf extract, and the rest is unchanged;
comparative example 4: compared with formula 3, the Cistanchis herba extract, stigma croci Sativi extract, industrial folium Cannabis extract, Saviae Miltiorrhizae radix extract and herba Centellae extract are replaced by Aloe extract (commercially available),
comparative example 5: compared with the formula 3, the composition does not contain cistanche extract, crocus extract, industrial hemp leaf extract, salvia miltiorrhiza extract and centella extract;
comparative example 6: compared with the formula 3, the traditional Chinese medicine composition does not contain the salvia miltiorrhiza extract and the centella asiatica extract, and the rest is unchanged.
Test example:
the herbal repair anti-allergic composition provided in example 1 of the present invention was tested for anti-allergic and repair efficacy and compared to the compositions of comparative examples 1-6:
firstly, preparing the toning lotion to be tested, wherein the specific preparation method is as follows (if a certain component is not contained in the formula, the component is not added in the preparation process):
putting a proper amount of water, 0.2 part by weight of xanthan gum and 0.02 part by weight of EDTA disodium into a vacuum emulsification tank, dissolving at 80-85 ℃ (preferably at 82 ℃), uniformly stirring, and cooling to 43-47 ℃ (preferably at 45 ℃); then sequentially adding the cistanche extract, the saffron extract, the industrial hemp leaf extract, the salvia miltiorrhiza extract, the centella extract, the aloe extract, the chamomile extract, the liquorice extract, the purslane extract, the rhodiola rosea extract and 0.5 weight part of ethylhexyl glycerin/phenoxyethanol preservative into a vacuum emulsification tank according to the formula amount, and uniformly dispersing; cooling to 32-35 deg.C (preferably 33 deg.C), defoaming, filtering, and discharging to obtain the final product.
Then, the antiallergic and repairing efficacies of the formulas 1 to 8 and the comparative examples 1 to 6 are tested:
in order to evaluate the anti-allergic and repairing effects of the composition, the lotions prepared according to the formulas 1 to 8 and the comparative examples 1 to 6 were tested on volunteers and participated in a test of 560 volunteers, wherein 280 men and 280 women are randomly divided into 14 groups, and 40 people in each group have different allergic symptoms such as pruritus, redness and swelling, rash, pox, stabbing pain, flushing, red face, red blood streak and the like; the prepared lotion is applied twice a day in the morning and evening, and the dosage in an area of 5cm multiplied by 5cm is 1 g each time; during the experiment, volunteers were unable to apply any other drugs to the experimental site.
(1) Anti-allergic efficacy:
after the volunteers continuously use the lotion for 1 day, 2 days and 7 days on the test part, the anti-allergic effect of the lotion is evaluated by taking the picture before smearing as a contrast; the volunteers were also asked to feel themselves after using the samples, etc., and the results were recorded as shown in Table 2. Comparative efficacy standards before and after recording:
and (3) healing: the allergic symptoms such as pruritus, red swelling, rash, pox, stabbing pain, blush, red blood streak and the like completely disappear, and the area of skin damage is improved by more than or equal to 95 percent.
The effect is shown: allergic symptoms such as pruritus, red swelling, herpes, pox, stabbing pain, flushing, red blood streak and the like are obviously improved, and the area of skin damage is improved by more than or equal to 75 percent.
The method has the following advantages: the allergic symptoms such as pruritus, red swelling, herpes, pox, stabbing pain, blush, red blood streak and the like are improved, and the area of skin damage is improved by more than or equal to 50 percent.
And (4) invalidation: allergic symptoms still exist, even with a deepening trend.
TABLE 2 antiallergic effect of lotions
(2) The efficacy of repair:
measuring the TEWL value of the percutaneous water loss by using a water dispersion loss instrument after 0 day, 1 day, 2 days and 7 days of continuous use of the toning lotion by volunteers at the test part, and calculating the average value; the repair efficacy of the compositions was evaluated by TEWL rate and the results used are shown in table 3.
TEWL change rate (average TEWL on day 0-TEWL at different time points)/average TEWL on day 0 × 100%.
Recording a repair effect standard: the effect is shown: the TEWL change rate is more than or equal to 50 percent; the method has the following advantages: 0% < TEWL rate of change < 50%; and (4) invalidation: the TEWL change rate is less than or equal to 0 percent.
TABLE 3 repairing and Using effects of lotions
As can be seen from tables 2 and 3, the herbal repair antiallergic composition provided by the formulas 1 to 8 in the embodiment 1 of the invention has a significant treatment effect on allergic symptoms such as skin itch, red swelling, rash, pox, stabbing pain, flushing, red blood streak, and the like; according to the reaction of volunteers, after the cosmetic is used for 7 days, the resistance to allergen is improved, the skin barrier can be repaired, and the cosmetic has a good water replenishing and locking effect; moreover, the effect is better after long-term use. Compared with the comparative examples 1 to 6, the cistanche extract, the crocus extract, the industrial cannabis sativa leaf extract, the salvia miltiorrhiza extract and the centella asiatica extract are key components for treating allergic symptoms such as skin itch, red swelling, rash, pox, stabbing pain, flushing, red blood streak and the like, and the anti-allergic effect is obvious when the cistanche extract, the crocus sativa leaf extract, the industrial cannabis sativa leaf extract, the salvia miltiorrhiza extract and the centella asiatica extract are compounded, so that the synergistic effect is reflected.
Example 2: the herbal repairing anti-allergic mask provided by the invention
(1) 1-5 mask
Table 4 formula of herbal repairing antiallergic mask in example 2
(2) Comparative examples 7 to 12
Comparative example 7: compared with the mask 3, the herbal repairing antiallergic composition is replaced by the composition in the comparative example 1, and the rest is unchanged;
comparative example 8: compared with the mask 3, the herbal repairing antiallergic composition is replaced by the composition in the comparative example 2, and the rest is unchanged;
comparative example 9: compared with the mask 3, the herbal repairing antiallergic composition is replaced by the composition in the comparative example 3, and the rest is unchanged;
comparative example 10: compared with the mask 3, the herbal repairing antiallergic composition is replaced by the composition in the comparative example 4, and the rest is unchanged;
comparative example 11: compared with the mask 3, the herbal repairing antiallergic composition is replaced by water, and the rest is unchanged;
comparative example 12: compared to mask 3, the herbal repair anti-allergic composition was replaced with the composition of comparative example 6, with the remainder unchanged.
The preparation method of the facial mask is as follows (when a certain component is not contained in the formula, the component is not added in the preparation process):
(1) putting water, glycerol, sodium hyaluronate, hydrolyzed sodium hyaluronate, hydroxyethyl urea, trehalose, glyceryl polyether-26, allantoin, p-hydroxyacetophenone, carbomer, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, xanthan gum, polyacrylic acid, hydroxyethyl cellulose, EDTA disodium, EDTA trisodium and EDTA tetrasodium into a vacuum emulsification tank, dissolving at 82 ℃, uniformly stirring, and cooling to 45 ℃ to obtain phase A;
(2) completely dissolving arginine, citric acid and sodium citrate with a part of water in a separate dissolving tank to obtain a phase B;
(3) completely dissolving butanediol, 1, 2-hexanediol, 1, 2-pentanediol, 1, 3-propanediol, essence, PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, PPG-26-butanol polyether, and Tween-20 in a separate dissolving tank to obtain phase C;
(4) sequentially adding the phase B and the phase C into a vacuum emulsification tank (phase A), and uniformly dispersing;
(5) sequentially adding Cistanchis herba extract, stigma croci Sativi extract, industrial folium Cannabis extract, Saviae Miltiorrhizae radix extract, herba Centellae extract, Aloe extract, flos Matricariae Chamomillae extract, Glycyrrhrizae radix extract, herba Portulacae extract, radix Rhodiolae extract, nicotinamide, ascorbyl glucoside, fructus Hippophae extract, radix Althaeae Roseae extract, semen Myristicae extract, herba Portulacae extract, BPN-desoro 1600solution, carnosine, dipeptide diaminobutyryl benzylamide diacetate, Prolevis, dipotassium glycyrrhizinate, sodium pyrosulfite, ethylhexyl glycerol, dextrin, polyethylene glycol-8, phenoxyethanol, potassium sorbate, and sodium benzoate into a vacuum emulsification tank, and uniformly dispersing;
(6) cooling to 33 ℃, defoaming, filtering and discharging;
(7) after being inspected to be qualified, the mask base cloth and the mask base cloth are filled into finished products, and the finished products are packaged and put in storage.
And (3) testing the efficacy:
evaluating the effects of the facial masks 1-5 and the facial masks of comparative examples 7-12; the specific test method is as follows:
in order to evaluate the anti-allergic and repairing effects of the mask, the mask participates in 440 test volunteers, wherein 220 male and 220 female patients are 20-50 years old and randomly divided into 11 groups, each group comprises 40 patients, and the volunteers have different allergic symptoms such as pruritus, red swelling, rash, pox, stabbing pain, flushing, red blood streak and the like.
And (3) testing the antiallergic efficacy: after the volunteers continuously use the mask on the test part for 7 days, the anti-allergic effect of the mask is evaluated by taking the picture before use as a contrast; the volunteers were also asked to feel themselves after using the samples, etc., and the results were recorded as shown in Table 5.
Testing the repairing efficacy: measuring the TEWL value of the transdermal water loss by using a water loss instrument after 0 day and 7 days of continuously using the mask on the test part of a volunteer, and calculating the average value; the repair efficacy of the compositions was evaluated by TEWL rate and the results are shown in table 5.
Evaluation of feeling of use: volunteers evaluated the feeling of use after 7 days of continuous use; people who feel more than 80% feel that the mask is very soft, close to the skin and breathable, the mask is rated as plus minus 60 percent, and the specific test results are shown in table 5.
Table 5 evaluation results of efficacy of mask
As can be seen from table 5, (1) efficacy: as can be seen by comparing the facial masks 1-5 with the comparative examples 7-12, the anti-allergic facial mask provided by the invention has a good anti-allergic effect; the facial mask 3 is compared with the facial masks 1-2 and the facial masks 4-5, the antiallergic effect is basically improved along with the increase of the addition amount of the antiallergic composition, but when the addition amount of the antiallergic composition in the facial mask is 1 part by weight, and the wormwood fibers are used as the facial mask base cloth, the antiallergic effect is optimal, and the facial mask base cloth of the wormwood fibers plays a role in promoting the effect of the antiallergic composition provided by the invention; as can be seen from comparison of the masks 1-5 with the comparative examples 7-10 and the comparative example 12, the antiallergic composition provided by the invention has the best effect when the raw materials are used together, which shows that the components of the antiallergic composition provided by the invention have a synergistic effect. (2) The use feeling is as follows: as can be seen by comparing the mask 3 with the masks 1-2 and 4-5, the mask base cloth is made of mugwort fiber, so that the mask base cloth is optimal in use feeling.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. A herbal repair antiallergic composition comprises the following components:
0.03-1.5 parts by weight of cistanche extract;
0.02-1 part by weight of crocus sativus extract;
0.02-1 part by weight of industrial hemp leaf extract;
0.02-1 part by weight of a salvia miltiorrhiza extract;
0.01-0.5 parts by weight of centella asiatica extract.
2. A herbal repairing and antiallergic facial mask comprises essence and facial mask base cloth;
the essence is prepared from the following raw materials:
71.622-94.56 parts by weight of a solvent;
0-11.75 parts by weight of a humectant;
0-1 part by weight of a solubilizer;
0.1-5 parts by weight of herbal repair antiallergic composition;
0.22-13.678 parts by weight of a skin conditioner;
0.1-0.8 parts of thickening agent;
0.02-0.1 part by weight of a chelating agent;
0-0.05 parts by weight of an aromatic;
0.1-0.6 parts by weight of a preservative;
0-0.3 part of pH regulator;
the herbal repair antiallergic composition of claim 1;
the facial mask base cloth is made of cuprammonium fibers, hydrogel, pure cotton fibers, biological fibers, viscose fibers, wormwood fibers or bamboo charcoal fibers.
3. The herbal remedial anti-allergy mask as claimed in claim 2, wherein the moisturizer is selected from one or more of glycerin, sodium hyaluronate, trehalose, hydrolyzed sodium hyaluronate, hydroxyethyl urea and glyceryl polyether-26.
4. The herbal remedial anti-allergy mask as claimed in claim 2, wherein the solubilizer is selected from one or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, PPG-26-butanol polyether and tween-20.
5. The herbal remedial anti-allergy mask as claimed in claim 2, wherein the skin conditioning agent is selected from one or more of niacinamide, ascorbyl glucoside, allantoin, sea buckthorn extract, marshmallow root extract, nutmeg extract, purslane extract, BPN-meso 1600solution, carnosine, dipeptide diaminobutyrobenzyl amide diacetate, Prolevis, dipotassium glycyrrhizinate, sodium metabisulfite, arginine, ethylhexylglycerin, p-hydroxyacetophenone, dextrin and polyethylene glycol-8.
6. The herbal remedial anti-allergy mask as claimed in claim 2, wherein the thickening agent is selected from one or more of carbomer, polyacrylic acid, xanthan gum, acrylic acid or acrylate/C10-30 alkanol acrylate crosspolymer, hydroxyethyl cellulose.
7. The herbal remedial anti-allergy mask as claimed in claim 2, wherein the chelating agent is selected from disodium EDTA, trisodium EDTA or tetrasodium EDTA.
8. The herbal remedial anti-allergy mask as claimed in claim 2, wherein the preservative is selected from one or more of phenoxyethanol, potassium sorbate and sodium benzoate.
9. The herbal remedial anti-allergy mask as claimed in claim 2, wherein the pH adjusting agent is selected from citric acid and/or sodium citrate.
10. A method for preparing a herbal repair anti-allergy mask as claimed in any one of claims 2 to 9, comprising the steps of:
a) uniformly mixing a solvent, a humectant, a solubilizer, a skin conditioner, a thickening agent, a chelating agent, an aromatic and a pH regulator in a vacuum emulsification tank; adding herbal repairing antiallergic composition and antiseptic, and dispersing; then cooling to 32-35 ℃, defoaming, filtering and discharging to obtain essence;
b) filling the essence obtained in the step a) and mask base cloth together to obtain the herbal repairing anti-allergic mask.
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| CN202010903872.4A CN111840187A (en) | 2020-09-01 | 2020-09-01 | Herbal repairing and antiallergic composition, mask and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114159369A (en) * | 2021-12-10 | 2022-03-11 | 江苏普罗诺生物科技有限公司 | Anti-wrinkle repair essence mask containing bluecopper peptides |
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2020
- 2020-09-01 CN CN202010903872.4A patent/CN111840187A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114159369A (en) * | 2021-12-10 | 2022-03-11 | 江苏普罗诺生物科技有限公司 | Anti-wrinkle repair essence mask containing bluecopper peptides |
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Address after: 344000 Jiangxi province Fuzhou Nancheng County Industrial Park third Applicant after: Jiangxi jianchangbang dietotherapy Technology Co.,Ltd. Address before: 344700 third industrial park, Nancheng County, Jiangxi, Fuzhou Applicant before: Jianchang Jiangxi Gang Pharmaceutical Co.,Ltd. |
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Application publication date: 20201030 |