CN111759903A - Traditional Chinese medicine ointment for treating psoriasis - Google Patents

Traditional Chinese medicine ointment for treating psoriasis Download PDF

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CN111759903A
CN111759903A CN202010617250.5A CN202010617250A CN111759903A CN 111759903 A CN111759903 A CN 111759903A CN 202010617250 A CN202010617250 A CN 202010617250A CN 111759903 A CN111759903 A CN 111759903A
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ointment
traditional chinese
chinese medicine
ethanol
treating psoriasis
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尚伟
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics

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Abstract

The invention discloses a traditional Chinese medicine ointment for treating psoriasis, which is prepared from the raw materials of belvedere fruit, phellodendron bark, toona sinensis fruit, leech, snake slough, radix sophorae flavescentis, borneol, glycerol, butter, vaseline, 95% ethanol and the like. The invention selects a plurality of traditional Chinese medicine components as raw materials, and the main medicines and the auxiliary medicines are mutually assisted and prepared to form the ointment according to the theory of traditional Chinese medicine, so that the ointment has remarkable sterilizing and inflammation diminishing functions, effectively improves the skin immunity, has no irritation to the skin, redness and pain after being used by patients, can quickly relieve itching and pain, has quick response and no side effect, has ideal effect on treating psoriasis, has simple preparation method, lower cost and convenient use by patients, and provides powerful technical support for curing the recurrent psoriasis.

Description

Traditional Chinese medicine ointment for treating psoriasis
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine ointment for treating psoriasis.
Background
Psoriasis, a chronic inflammatory skin disease, has a long course of disease and a tendency of easy recurrence, and some cases are not cured almost for the whole life. The disease is mainly developed in young and old years, and has great influence on the physical health and mental conditions of patients. The clinical manifestations mainly include erythema and scales, all diseases occur in the whole body, the scalp and the limbs are common, and the disease is aggravated in winter.
The traditional Chinese medicine considers that psoriasis: the pathogenic factors are blood deficiency and dryness-heat, and when the skin is affected by external wind and fails to nourish qi and blood, the blood heat and wind dryness can affect the skin, enter the blood system to cause nutrient and defensive diseases, and the qi-blood imbalance and pathogenic toxin are struggled against the skin to cause the disease. Psoriasis is considered by western medicine: the etiology is caused by factors such as genetic inheritance of the attribution gene, immune dysfunction, change of ecological environment and the like. In the prior art, psoriasis is one of persistent diseases in related skin diseases, and is a common disease and frequently encountered diseases which seriously affect the health of people, such as skin diseases caused by psoriasis, porrigo, tinea cruris, tinea corporis, tinea manuum and tinea pedis, eczema, allergy, pruritus and chilblain. The skin disease is a pathological process and various corresponding clinical manifestations caused by the change of the form, structure and function of the skin under the influence of internal and external factors. Due to changes of natural environment and ecological environment, atmospheric pollution and changes of dietary structure, serious imbalance of mineral trace elements of a human body is caused, the incidence rate of skin diseases is higher and higher, health and life quality are affected slightly, and serious people endanger life.
At present, the medicines of hormones, chemicals and traditional Chinese medicines for treating skin diseases on the market are various, wherein the external medicines for treating psoriasis generally comprise tar preparations, anthralin, glucocorticoid and the like, although the formulas are different, the curative effect is poor, the side effect is more, and the medicines become common diseases of the medicines.
Disclosure of Invention
The invention aims to make up the defects of the prior art and provides the traditional Chinese medicine ointment for treating psoriasis.
In order to achieve the above object, the present invention provides the following technical solutions:
a traditional Chinese medicine ointment for treating psoriasis comprises the following raw materials in percentage by mass: 550 g of belvedere fruit, 550 g of amur corktree bark, 450 g of amur corktree bark, 500 g of toona fruit, 220 g of leech, 270 g of snake slough, 230 g of lightyellow sophora root, 16-24 g of borneol, 40-60 g of glycerol, 40-60 g of butter, 550 g of vaseline and 1200 g of 95% ethanol.
Further, the traditional Chinese medicine ointment for treating psoriasis comprises the following raw materials in parts by mass: 480-520 g of belvedere fruit, 480-520 g of amur corktree bark, 480-520 g of toona sinensis, 240-260 g of leech, 240-260 g of snake slough, 240-260 g of lightyellow sophora root, 18-22 g of borneol, 45-55 g of glycerol, 45-55 g of butter, 480-520 g of vaseline and 900-1100 g of 95 percent ethanol.
Furthermore, the traditional Chinese medicine ointment for treating psoriasis comprises the following raw materials in percentage by mass: 500 g of belvedere fruit, 500 g of amur corktree bark, 500 g of Chinese toona fruit, 250 g of leech, 250 g of snake slough, 250 g of lightyellow sophora root, 20 g of borneol, 50 g of glycerol, 50 g of butter, 500 g of vaseline and 1000 g of 95% ethanol.
The invention also provides a preparation method of the traditional Chinese medicine ointment for treating psoriasis, which comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials according to the mass ratio for later use;
(2) pulverizing fructus Kochiae, cortex Phellodendri, fructus Toonnae sinensis, Hirudo, periostracum Serpentis, and radix Sophorae Flavescentis, mixing, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent A;
(3) mixing Borneolum Syntheticum, glycerol, vaseline, and butter, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent B;
(4) mixing the ointment A and the ointment B, stirring and reacting for 1 hour to obtain the ointment of the invention.
The application method of the traditional Chinese medicine ointment for treating psoriasis is to apply the ointment to the affected part once a day in the morning and at night.
The traditional Chinese medicine prescription:
the preparation method comprises the following steps of (1) preparing broom cypress fruit: has the effects of clearing heat, promoting diuresis, dispelling pathogenic wind and relieving itching.
Phellodendron bark: has the effects of clearing heat, eliminating dampness, purging fire, removing steam, removing toxic substance and treating sore.
Chinese toon seed: has effects in expelling pathogenic wind, dispelling cold, and relieving pain.
Leech: has the effects of breaking blood, stimulating the menstrual flow, removing blood stasis and eliminating the symptoms.
Snake slough: has the functions of dispelling wind, arresting convulsion, removing nebula and detoxicating.
Flavescent sophora root: has the effects of clearing heat, eliminating dampness, killing parasites and promoting urination.
Borneol: has the effects of inducing resuscitation, refreshing mind, clearing away heat and toxic materials, improving eyesight, and eliminating nebula.
Glycerol: it can be used in ointment for moistening skin.
Butter oil: caring skin, and keeping skin smooth and glossy.
Vaseline: can moisturize and repair skin, and relieve dry skin and various skin problems caused by the dry skin.
The invention has the advantages that:
the invention selects a plurality of traditional Chinese medicine components as raw materials, and the main medicines and the auxiliary medicines are mutually assisted and prepared to form the ointment according to the theory of traditional Chinese medicine, so that the ointment has remarkable sterilizing and inflammation diminishing functions, effectively improves the skin immunity, has no irritation to the skin, redness and pain after being used by patients, can quickly relieve itching and pain, has quick response and no side effect, has ideal effect on treating psoriasis, has simple preparation method, lower cost and convenient use by patients, and provides powerful technical support for curing the recurrent psoriasis.
Detailed Description
The technical scheme of the invention is further explained by combining the specific examples as follows:
example 1
A traditional Chinese medicine ointment for treating psoriasis comprises the following raw materials by mass: 500 g of belvedere fruit, 500 g of amur corktree bark, 500 g of Chinese toona fruit, 250 g of leech, 250 g of snake slough, 250 g of lightyellow sophora root, 20 g of borneol, 50 g of glycerol, 50 g of butter, 500 g of vaseline and 1000 g of 95% ethanol.
The preparation method of the traditional Chinese medicine ointment for treating psoriasis comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials according to the mass ratio for later use;
(2) pulverizing fructus Kochiae, cortex Phellodendri, fructus Toonnae sinensis, Hirudo, periostracum Serpentis, and radix Sophorae Flavescentis, mixing, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent A;
(3) mixing Borneolum Syntheticum, glycerol, vaseline, and butter, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent B;
(4) mixing the ointment A and the ointment B, stirring and reacting for 1 hour to obtain the ointment of the invention.
Example 2
A traditional Chinese medicine ointment for treating psoriasis comprises the following raw materials by mass: 480 g of fructus kochiae, 480 g of golden cypress, 480 g of toona sinensis, 240 g of leech, 240 g of snake slough, 240 g of radix sophorae flavescentis, 18 g of borneol, 45 g of glycerol, 45 g of butter, 480 g of vaseline and 900 g of 95% ethanol.
The preparation method of the traditional Chinese medicine ointment for treating psoriasis comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials according to the mass ratio for later use;
(2) pulverizing fructus Kochiae, cortex Phellodendri, fructus Toonnae sinensis, Hirudo, periostracum Serpentis, and radix Sophorae Flavescentis, mixing, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent A;
(3) mixing Borneolum Syntheticum, glycerol, vaseline, and butter, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent B;
(4) mixing the ointment A and the ointment B, stirring and reacting for 1 hour to obtain the ointment of the invention.
Example 3
A traditional Chinese medicine ointment for treating psoriasis comprises the following raw materials by mass: 520 g of belvedere fruit, 520 g of amur corktree bark, 520 g of Chinese toona fruit, 260 g of leech, 260 g of snake slough, 260 g of lightyellow sophora root, 22 g of borneol, 55 g of glycerol, 55 g of butter, 520 g of vaseline and 1100 g of 95% ethanol.
The preparation method of the traditional Chinese medicine ointment for treating psoriasis comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials according to the mass ratio for later use;
(2) pulverizing fructus Kochiae, cortex Phellodendri, fructus Toonnae sinensis, Hirudo, periostracum Serpentis, and radix Sophorae Flavescentis, mixing, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent A;
(3) mixing Borneolum Syntheticum, glycerol, vaseline, and butter, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent B;
(4) mixing the ointment A and the ointment B, stirring and reacting for 1 hour to obtain the ointment of the invention.
Typical case 1
One of Yang, a woman, 56 years old, Kongshang Fuyang city Yingdong district Harmonious community. The psoriasis of the patient is more than 20 years old and is treated all over the country, but the psoriasis is not ideal, and the psoriasis of the whole body is completely clear after taking the medicine from the spring of 2017 for one month after trial, and does not relapse until now.
Typical case 2
Some of the points of Dong, male, age 38, family lived in Fuyang city, Yingzhou suburban community. In the spring of 2015, the patient introduced to his place to take the medicine by others. The patient just sees the disease from Shanghai, and if psoriasis in the whole body is not well treated, the patient can try the product for one month, then the psoriasis is cured on the whole body, and the psoriasis does not relapse to the present.
Typical case 3
One of the young, women, 32 years old, and the town of Ninglaozhuang, Yingquan district, Fuyang city, Jia. The patient suffers from psoriasis about six years, the whole body is available, many hospitals can not cure the psoriasis, the whole body is clear after the psoriasis is taken for one month in 2016, no scar is left, and the psoriasis does not relapse to the present.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.

Claims (5)

1. The traditional Chinese medicine ointment for treating psoriasis is characterized by comprising the following raw materials in parts by mass: 550 g of belvedere fruit, 550 g of amur corktree bark, 450 g of amur corktree bark, 500 g of toona fruit, 220 g of leech, 270 g of snake slough, 230 g of lightyellow sophora root, 16-24 g of borneol, 40-60 g of glycerol, 40-60 g of butter, 550 g of vaseline and 1200 g of 95% ethanol.
2. The traditional Chinese medicine ointment for treating psoriasis according to claim 1, which is characterized by comprising the following raw materials in percentage by mass: 480-520 g of belvedere fruit, 480-520 g of amur corktree bark, 480-520 g of toona sinensis, 240-260 g of leech, 240-260 g of snake slough, 240-260 g of lightyellow sophora root, 18-22 g of borneol, 45-55 g of glycerol, 45-55 g of butter, 480-520 g of vaseline and 900-1100 g of 95 percent ethanol.
3. The traditional Chinese medicine ointment for treating psoriasis according to claim 1, which is characterized by comprising the following raw materials in percentage by mass: 500 g of belvedere fruit, 500 g of amur corktree bark, 500 g of Chinese toona fruit, 250 g of leech, 250 g of snake slough, 250 g of lightyellow sophora root, 20 g of borneol, 50 g of glycerol, 50 g of butter, 500 g of vaseline and 1000 g of 95% ethanol.
4. A method for preparing a traditional Chinese medicine ointment for treating psoriasis as claimed in claim 1, which comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials according to the mass ratio for later use;
(2) pulverizing fructus Kochiae, cortex Phellodendri, fructus Toonnae sinensis, Hirudo, periostracum Serpentis, and radix Sophorae Flavescentis, mixing, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent A;
(3) mixing Borneolum Syntheticum, glycerol, vaseline, and butter, adding 95% ethanol, stirring to obtain paste, standing, and volatilizing for 1 hr to obtain unguent B;
(4) mixing the ointment A and the ointment B, stirring and reacting for 1 hour to obtain the ointment of the invention.
5. A method of using a Chinese medicinal ointment according to any one of claims 1 to 4 for the treatment of psoriasis, wherein the ointment is applied to the affected area once a day, morning and evening.
CN202010617250.5A 2020-07-01 2020-07-01 Traditional Chinese medicine ointment for treating psoriasis Pending CN111759903A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102114166A (en) * 2010-01-04 2011-07-06 孔静波 Chinese medicinal ointment and manufacturing method thereof
CN108853243A (en) * 2018-08-27 2018-11-23 谢允超 Treat psoriasic xanthate cream itself and preparation method
CN110179880A (en) * 2019-07-09 2019-08-30 许富明 A kind of draft bacteriostatic agent and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102114166A (en) * 2010-01-04 2011-07-06 孔静波 Chinese medicinal ointment and manufacturing method thereof
CN108853243A (en) * 2018-08-27 2018-11-23 谢允超 Treat psoriasic xanthate cream itself and preparation method
CN110179880A (en) * 2019-07-09 2019-08-30 许富明 A kind of draft bacteriostatic agent and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
赵晓山,等: "寻常型银屑病治验", 《光明中医》 *
陈晓霞: "中药药浴联合NB-UVB照射治疗寻常型银屑病疗效观察及护理", 《四川医学》 *

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Application publication date: 20201013