CN111616354A - An oral composition with skin caring effect, and its preparation method - Google Patents

An oral composition with skin caring effect, and its preparation method Download PDF

Info

Publication number
CN111616354A
CN111616354A CN202010434826.4A CN202010434826A CN111616354A CN 111616354 A CN111616354 A CN 111616354A CN 202010434826 A CN202010434826 A CN 202010434826A CN 111616354 A CN111616354 A CN 111616354A
Authority
CN
China
Prior art keywords
powder
parts
oral composition
skin
fructo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202010434826.4A
Other languages
Chinese (zh)
Inventor
邹坚
李桂珠
刘婕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Meixin Hi Tech Co ltd
Original Assignee
Beijing Meixin Hi Tech Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Meixin Hi Tech Co ltd filed Critical Beijing Meixin Hi Tech Co ltd
Priority to CN202010434826.4A priority Critical patent/CN111616354A/en
Publication of CN111616354A publication Critical patent/CN111616354A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385—Concentrates of non-alcoholic beverages
    • A23L2/39—Dry compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to an oral composition with a beautifying function and a preparation method thereof, and the oral composition contains active ingredients comprising: polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage collagen, marine fish collagen, pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide; processing the above active ingredients and/or pharmaceutically acceptable adjuvants to make into various oral preparations; the preparation of the invention is convenient to take, and experiments prove that the preparation has effective beautifying function.

Description

An oral composition with skin caring effect, and its preparation method
Technical Field
The invention relates to the technical field of compositions, in particular to an oral composition with a beautifying function and a preparation method thereof.
Background
The aging of the body is characterized by "Atrophy" and "regression" (Atrophy) of tissues and organs, which is essentially the essential component of the tissues and organs-loss of cells and extracellular matrix. The same is true of the skin as a tissue organ of the body. The thickness of the skin is reduced by about 6% every decade, as measured by the active tissue of the skin in each age group. However, there are large differences between descending individuals, some slow but some fast, due to internal and external factors such as genetics or acquired environment. These internal and external factors ultimately lead to two main consequences: one is the decline of cellular biological activity (reduced capacity to proliferate and synthesize extracellular matrix itself); the second is that the catabolism of the organism is enhanced and the extracellular matrix is degraded. In the latter result, in the face of aging, a large number of extracellular matrices are degraded, and the degradation of a macromolecular fibrillar protein called elastin is closely related to the aging of the skin.
With age, the composition of elastin in the skin decreases, concomitantly decreasing the network support required to maintain tight skin, with the result that the skin becomes lax and blurred in contour.
Elastin acts as a rubber band in the skin, allowing the skin to stretch and fold, and functions like a spring in a mattress, which is responsible for maintaining and supporting the elasticity of the skin. Therefore, elastin plays an important role in maintaining skin elasticity.
After 25 years of age, elastin production stops, elastin in skin continuously passes, and skin begins to relax and has fine wrinkles and other aging phenomena. Scientific studies have demonstrated that the age of the skin is determined by the percentage of elastin, only elastin being able to provide and maintain the two-dimensional elasticity of the skin.
Many people think that the key point of maintaining youthful skin is how to supplement collagen, and the elastin which is another important substance in the fibroblasts is ignored. It plays the role of a rubber band in the skin,
if the beauty health care product and the beauty food have the elastin and the collagen components at the same time, the beauty health care product and the beauty food have good effect on keeping young, fine and elastic skin.
The invention provides a special product for women, which has the effects of increasing skin elasticity, resisting saccharification, whitening, eliminating free radicals, preserving moisture and the like. Is a novel rejuvenating product, nourishes the female internally and externally, and makes the female skin elastic and beautiful.
Disclosure of Invention
The invention aims to provide an oral composition with a beautifying function and a preparation method thereof.
The invention is realized by the following technical scheme:
an oral composition having cosmetic function, comprising as active ingredients: the feed comprises polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen peptide, red pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide. The health product comprises the following active components in parts by weight: 0.1-0.5 part of polished rice juice powder, 0.1-0.5 part of micromolecular elastin peptide, 0.1-0.5 part of fermented composite fruit and vegetable powder, 5-10 parts of cartilage extract, 10-50 parts of marine fish collagen peptide, 1-5 parts of red pomegranate powder, 1-5 parts of acerola cherry powder, 1-5 parts of tremella powder and 5-35 parts of fructo-oligosaccharide. Preferably, the health care product is prepared from the following active ingredients in parts by weight: 0.15-0.35 part of polished rice juice powder, 0.15-0.35 part of micromolecular elastin peptide, 0.15-0.35 part of fermented composite fruit and vegetable powder, 6-8 parts of cartilage extract, 25-50 parts of marine fish collagen peptide, 1.5-3.5 parts of red pomegranate powder, 1.5-3.5 parts of acerola cherry powder, 2-4 parts of tremella powder and 10-35 parts of fructo-oligosaccharide. More preferably, the health care product is prepared from the following active ingredients in parts by weight: 0.16875 parts of polished rice juice powder, 0.125 part of micromolecular elastin peptide, 0.3125 parts of fermented composite fruit and vegetable powder, 6.25 parts of cartilage extract, 50 parts of marine fish collagen peptide, 2.5 parts of red pomegranate powder, 2.5 parts of acerola cherry powder, 2.5 parts of tremella powder and 35 parts of fructo-oligosaccharide.
An oral composition with a beautifying function, wherein the preparation is an oral preparation; the method comprises the following steps: granule, solid beverage, tablet, milk tablet, yogurt tablet, colostrum tablet, chewable tablet, honeyed pill, concentrated honeyed pill, water honeyed pill, concentrated water honeyed pill, oral liquid preparation, bagged tea, decocted tea, beverage, powder, sugar, medicated wine, and confection.
An oral composition with beauty function, which comprises the active component and the auxiliary material; the auxiliary materials comprise citric acid, stevioside, edible essence, natural menthol, strawberry essence, starch, mannitol, aspartame, magnesium stearate, xylitol and microcrystalline cellulose.
An oral composition with a beautifying function comprises, by weight, 40-90 parts of active ingredients and 10-60 parts of auxiliary materials.
An oral composition having a cosmetic function, the process for preparing the composition comprising: taking the refined rice juice powder, the micromolecular elastin peptide, the fermented composite fruit and vegetable powder, the cartilage extract, the marine fish collagen peptide, the red pomegranate powder, the acerola cherry powder, the tremella powder and the fructo-oligosaccharide according to the formula amount, sieving, mixing, adding auxiliary materials, uniformly mixing, and preparing the required oral preparation according to the conventional process.
An oral composition with a beautifying function is prepared by the following steps: taking polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen peptide, red pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide according to the formula amount, sieving, mixing, adding auxiliary materials, uniformly mixing and packaging to obtain the solid beverage.
The efficacy of each active ingredient of the invention is as follows:
the polished rice juice powder is derived from Japanese brown rice and is rich in ceramide at 1.0% or more. Ceramide (ceramide), a lipid present in the intercellular spaces of the stratum corneum of human skin, is an important and high-proportion component of stratum corneum lipids, and the total content thereof is about 40 to 55% of intercellular lipids. When the skin ages, the amount of Ceramide is reduced, so that the stratum corneum cannot retain water and nutrients, and the skin is dry, poor and fine. And the water loss can be reduced by increasing the adhesive force of glial cells through external wiping or oral supplement of Ceramide, so that the moisturizing effect is achieved.
The polished rice juice powder disclosed by the invention is rich in ceramide, can fully supplement skin moisture, has the effects of moisturizing, tightening and resisting saccharification, and enables the skin to become Q elastic and moist, white and anti-wrinkle by nourishing the inside and the outside through a gold formula.
Elastin is a protein that constitutes elastic fibers, and is widely distributed in various tissues and organs in the living body, and is mainly present in elastic tissues such as cervical ligaments, blood vessels, lungs, and skin. Such tissues not only require elasticity but also tensile strength, and elastin plays an important role in the formation and maintenance of morphology. Elastin is rich in hydrophobic amino acids such as glycine, alanine, valine and the like, and in the process of elastin biosynthesis, the precursor of elastin, namely elastin, forms amino acids, desmosine and isodesmosine through lysyl oxidase, and interferes with a cross-linked structure formed by four lysine residues, so that elastin is helpful for maintaining the stability and elasticity of a tissue structure.
The plant fruit and vegetable enzyme is a compound enzyme, is compounded after fermentation of various fruits and vegetables, and has multiple functions; the plant fruit and vegetable enzyme not only has multiple enzymes with high-efficiency decomposition function, but also contains secondary metabolites of multiple microorganisms, trace elements and vegetable and fruit dietary fibers, and also contains components of the Chinese herbal medicine prescription, and the effect of the plant fruit and vegetable enzyme cannot be provided by the complex enzyme. The ferment contains vitamins and minerals, and also contains secondary metabolite and trace elements, more importantly, the ferment is prepared by fermenting natural fruits and vegetables, and has higher absorption efficiency than general synthesized comprehensive vitamins.
Cartilage extract belongs to type II collagen, is a special type of collagen ubiquitous in humans, is a constituent of articular cartilage extract, is more soluble in water, and may be referred to as dissolved collagen. It is administered orally to reduce inflammation such as osteoarthritis and rheumatism, and is beneficial to joint and skin health, and has antioxidant and free radical scavenging effects, and can inhibit skin aging caused by ultraviolet radiation. Clinical studies have demonstrated that it can promote skin health.
The fish collagen is a biological macromolecule which is prepared by protease degradation treatment, has the molecular weight of about 700-800 daltons, and has strong adsorbability. The fish collagen peptide is prepared from deep-sea fish as a raw material by multiple processes of unique biological enzyme enzymolysis, deodorization, decoloration and the like, and the product is rich in amino acid required by a human body, is completely water-soluble and has no trouble of animal epidemic diseases. Has the following effects: 1. skin brightening: the deep-sea fish skin collagen has good water retention capacity, so that the skin is moist and bright and emits healthy luster. 2. Tightening and preventing wrinkles: when the deep-sea fish skin collagen is absorbed by the skin, the deep-sea fish skin collagen is filled between the skin and the dermis to increase the skin compactness, generate the skin tension, shrink pores and enable the skin to be tight and elastic. When the skin is aged to generate wrinkles, the collagen can be improved and even removed. Can effectively accelerate the growth of cells in the dermis, activate epidermal cells, keep the elasticity and the firmness of the skin and prevent wrinkles. 3. And (3) moisturizing: because of the similarity of the deep-sea fish skin collagen and the skin stratum corneum structure, the deep-sea fish skin collagen has good affinity and compatibility with the skin, can permeate into the skin epidermis layer, can form a skin membrane, protects the skin, moistens and softens the skin, and promotes the fine shrinkage of the pores; and combines with water in the horny layer to form a net structure, locks water, is absorbed by the skin, plays the role of natural moisturizing factors, makes the skin plump, stretches wrinkles and effectively prevents aging.
Pomegranate juice is known as the super fruit in nature, and pomegranate juice has stronger antioxidant function than any fruit juice. Pomegranate fruit contains 0.2% -1% of antioxidant, mainly anthocyanins, catechins, tannins, gallic acid and ellagic acid, wherein key antioxidant punicalin and ellagic acid precursor. Increasing cell activity and repairing power, accelerating human body cell metabolism, improving human body self defense barrier, inhibiting casamino acid enzyme, inhibiting activity of collagenase and elastase in human body cells, and promoting blood vessel microcirculation by antioxidation.
The acerola cherry is famous for being rich in natural vitamin C, also contains a large amount of oxidation resistant components such as bioflavonoids, procyanidine and the like, cooperates with active small molecular peptides, cordyceps militaris and a component for resisting oxidation and improving immunity widely used in Europe and America, joins elderberry, and has the effects of nutrition intervention immunity and health maintenance.
The honeysuckle-tremella tea has mild nature, sweet and light taste and no toxicity, has the effects of tonifying spleen and promoting appetite, has the effects of benefiting qi and clearing intestines, and can nourish yin and moisten lung. The long-term taking of the acne cream can moisten skin and remove freckles, can provide sufficient nutrients for skin cells, prevent skin aging, and has good effects of preventing acnes and eliminating acne marks.
Fructo-oligosaccharide is a natural new generation of growth promoting substance which is praised as the most potential after the age of antibiotics, is called protogenesis in the French nation, is water-soluble dietary fiber, can influence lipid metabolism such as serum cholesterol and the like after being taken for a long time, is beneficial to the balance of intestinal flora, proliferates bifidobacterium, promotes the absorption of calcium and iron, resists decayed teeth and other nutritional functions, has low heat value, can not cause obesity, and is a good sweetening agent for diabetics. Experiments prove that the fructo-oligosaccharide can promote the absorption rate of calcium to reach 70.8%. Meanwhile, the natural formation of vitamins B1, B2, B3, B6, B12 and folic acid can be promoted, the improvement of skin conditions of face sores, black spots, freckles, whelks and old spots is facilitated, the skin is promoted to be bright, the diarrhea and constipation are intervened, the liver burden is relieved, the effect of protecting the liver is achieved, toxic metabolites are quickly discharged out of the body, and the health-care food is a high-quality low-calorific-value prebiotic.
In conclusion, the active ingredients of the invention, namely the refined rice juice powder, the small molecular elastin peptide, the fermented composite fruit and vegetable powder, the cartilage extract, the marine fish collagen peptide, the red pomegranate powder, the acerola powder, the tremella powder and the fructooligosaccharide, have the functions of maintaining beauty and keeping young.
Detailed Description
Example 1
4g of polished rice juice powder, 0.8g of micromolecular elastin peptide, 4g of fermented composite fruit and vegetable powder, 40g of cartilage extract, 80g of marine fish collagen peptide, 8g of pomegranate powder, 8g of acerola cherry powder, 16g of tremella powder and 40g of fructo-oligosaccharide.
Taking the formula amount of polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen peptide, red pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide, uniformly mixing, granulating, drying, and pressing into 1000 tablets to obtain the chewable tablets.
Example 2
0.8g of polished rice juice powder, 4g of micromolecular elastin peptide, 0.8g of fermented composite fruit and vegetable powder, 80g of cartilage extract, 160g of marine fish collagen peptide, 40g of pomegranate powder, 40g of acerola cherry powder, 40g of tremella powder and 280g of fructo-oligosaccharide
Taking the formula amount of polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen peptide, red pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide, mixing, sieving, adding the formula amount of starch, uniformly mixing, granulating, adding talcum powder, uniformly mixing, pressing into 1000 tablets, and coating to obtain the tablets.
Example 3
2g of polished rice juice powder, 2g of micromolecular elastin peptide, 2g of fermented composite fruit and vegetable powder, 80g of cartilage extract, 400g of marine fish collagen peptide, 20g of pomegranate powder, 8g of acerola cherry powder, 20g of tremella powder and 80g of oligofructose.
Taking the formula amount of polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen peptide, red pomegranate powder, acerola powder, tremella powder and fructo-oligosaccharide, mixing, sieving, adding the formula amount of citric acid and sucralose, crushing, sieving, uniformly mixing and packaging to obtain the granules.
Example 4
1.6875g of polished rice juice powder, 1.25g of micromolecular elastin peptide, 3.125g of fermented composite fruit and vegetable powder, 62.5g of cartilage extract, 500g of marine fish collagen peptide, 25g of red pomegranate powder, 25g of acerola cherry powder, 25g of tremella powder and 350g of fructo-oligosaccharide.
Taking the formula amount of polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen peptide, red pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide, mixing, sieving, adding citric acid and sucralose, mixing uniformly, and packaging to obtain the solid beverage.
Example 5: functional pharmacological test
Subject:
the skin care product is aged 30-55 years and has skin moisture content of 12 or less, and can be used as a subject affected by skin moisture;
female with age of 35-65 years and chloasma on face can be used as the subject for removing chloasma on skin.
The test products were: composition products of examples 1, 2, 3 and 4
Instruments and reagents: SHP88 skin Analyzer (Courage + Khazaka, Germany); the brown color card is designed and developed by the geographical research institute of Chinese academy of sciences, in accordance with "practical Standard color card" (1 st edition).
Experimental design and object grouping: the test for improving skin moisture and the test for removing chloasma both adopt two contrast designs of self and group, according to the conditions of skin moisture and chloasma on the face, the observation objects are respectively divided into 5 groups according to a randomly designed grouping method, and each group comprises 10 cases: control, example 1, example 2, example 3 and example 4.
Dosage and test period: the dose of each example group was 16 g/person/day according to the recommended dose of the present composition, and the control group was a blank control. The cycle was 6 weeks, i.e., 42 days. The subjects discontinued the use of drugs or health foods and cosmetics relevant to the purpose of the test during the test period.
Observation indexes and judgment:
(1) moisture content of skin: forehead glabellar skin is selected as the measurement site. Cleaning the tested part with clean cotton ball dipped with distilled water under quiet state, wiping to dry, and measuring water content 15min before and after test by the same instrument and the same person. All the operations are carried out in an inspection room with spacious space, good ventilation condition, stable temperature, humidity and other space environments;
(2) chloasma on the face: according to the judgment standard that the brown (Y + M + BK, namely the stack color of yellow + magenta + black) color card in the 'use standard color card' is the chloasma color shade: i degrees (15, 20, 5), II degrees (30, 40, 10), III degrees (40, 60, 15).
(3) The chloasma area on the face is: measuring the length (cm) and width (cm) of the same chloasma before and after the test with a ruler, and calculating the area (cm)2)。
(4) Judging the efficacy of chloasma:
the method has the following advantages: the chloasma color is reduced by I degree or the area is reduced by more than or equal to 10 percent, and new chloasma is not generated;
and (4) invalidation: the area of chloasma color is less than 10%, and the color has no obvious change.
The statistical method comprises the following steps:
analytical data were calculated using SPSS17.0 statistical software. The comparison of self-contrast data adopts paired t test: carrying out the homogeneity test of the variance on the two groups of mean values in a relatively idle mode, carrying out proper variable conversion on data with non-normal distribution or uneven variance, and carrying out t test on the converted data after the normal distribution and the homogeneity of the variance are met; if the converted data can not meet the requirements of normal score and homogeneity of variance, the t' test or the rank sum test is adopted; but the data with too large Coefficient of Variation (CV) (such as CV > 50%) is tested by rank sum; the comparison of efficacy indices was tested using X2.
The experimental results are as follows:
(1) test for improving skin moisture:
TABLE 1 comparison of the effects on skin moisture
Figure BSA0000208921890000061
Figure BSA0000208921890000062
Figure BSA0000208921890000071
As can be seen from the data in table 1: before taking, the comparison of each group of the control group and the test group shows that the skin moisture difference between the control group and the test group has no significant difference and has no statistical significance (P is more than 0.05).
After the medicine is taken, the skin moisture of the control group is increased to 7.58 +/-1.70 from 7.31 +/-1.85 before the medicine is taken, the improvement is less, and the change is basically avoided.
After administration, the skin moisture increased from 7 to 9 levels in each test group, and the data are shown in Table 1. The improvement is very obvious, and the improvement degree reaches a very obvious level (P is less than 0.01); is obviously higher than the control group.
The above results show that the compositions of examples 1, 2, 3 and 4 can improve skin moisture significantly, and the improvement degree is significantly higher than that of the control group.
(2) Chloasma function test
The effect of the shade of chloasma is shown in table 2:
TABLE 2 comparison of the effects on the change of the shade of chloasma
Figure BSA0000208921890000072
Figure BSA0000208921890000073
The effect of chloasma area is shown in table 3:
TABLE 3 comparison of the effects on the change of the chloasma area of the skin
Figure BSA0000208921890000074
Figure BSA0000208921890000075
As can be seen from the data in tables 2 and 3:
before taking, the comparison of each group of the control group and the test group, and the comparison of the area difference of chloasma and yellowish-brown speckles among the groups have no significant difference and have no statistical significance (P is more than 0.05).
After the medicine is taken, the chloasma color of the control group is reduced to 2.01 from 2.06 before the medicine is taken, and the chloasma area is reduced to 58.28 from 61.85 before the medicine is taken, and basically, the change is not caused.
After the administration, the reduction value of the chloasma in the groups of examples 1, 2, 3 and 4 is between 0.25 and 0.32, the reduction value of the area of the chloasma is between 8.43 and 10.75, the reduction is very obvious, and the degree of the reduction improvement reaches a very obvious level (P is less than 0.01), which is very obviously lower than that of the control group.
The results show that the groups of examples 1, 2, 3 and 4 can improve the chloasma color and the chloasma area, and the improvement degree is obviously higher than that of the control group.
(3) The effective rate of the chloasma is compared:
and (3) judging standard:
the method has the following advantages: the chloasma color is reduced by I degree or the area is reduced by more than or equal to 10 percent, and new chloasma is not generated;
and (4) invalidation: the area of chloasma color is less than 10%, and the color has no obvious change.
The effective and effective data of the efficacy are shown in table 4:
TABLE 4 chloasma-removing efficacy index t2Inspection comparison
Figure BSA0000208921890000081
As can be seen from the data in table 4:
after the medicine is taken, the effective rate of the color of a control group is 20 percent, the effective rate of the medicine for improving chloasma area is 30 percent, and the total effective rate is 25 percent; the effective rate of improving chloasma in the groups 1, 2, 3 and 4 is 80-90%, the effective rate of improving the area of the chloasma is 80-90%, no new chloasma appears, the effective rate is obviously higher than that of the control group, and the difference level reaches a very obvious level (P is less than 0.01).
In summary, the results of example 5 show that the compositions of examples 1, 2, 3 and 4 have significant effects of improving skin moisture and removing chloasma.
The above description is only a basic description of the concept of the present invention, and any modification and increase made according to the main formula technical scheme of the present invention shall fall within the protection scope of the present invention.

Claims (9)

1. An oral composition having cosmetic properties, comprising as active ingredients: polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen, red pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide.
2. The oral composition with the beauty function according to claim 1, wherein the health product is prepared from the following active ingredients in parts by weight: 0.1-0.5 part of polished rice juice powder, 0.1-0.5 part of small molecular elastin peptide, 0.1-0.5 part of fermented composite fruit and vegetable powder, 5-10 parts of cartilage extract, 10-50 parts of marine fish collagen, 1-5 parts of red pomegranate powder, 1-5 parts of acerola cherry powder, 1-5 parts of tremella powder and 5-35 parts of fructo-oligosaccharide.
3. The oral composition with the beauty function according to claim 2, wherein the health product is prepared from the following active ingredients in parts by weight: 0.15-0.35 part of polished rice juice powder, 0.15-0.35 part of micromolecular elastin peptide, 0.15-0.35 part of fermented composite fruit and vegetable powder, 6-8 parts of cartilage extract, 25-50 parts of marine fish collagen peptide, 1.5-3.5 parts of red pomegranate powder, 1.5-3.5 parts of acerola cherry powder, 2-4 parts of tremella powder and 10-35 parts of fructo-oligosaccharide.
4. The oral composition with the beauty function according to claim 3, wherein the health product is prepared from the following active ingredients in parts by weight: 0.16875 parts of polished rice juice powder, 0.125 part of micromolecular elastin peptide, 0.3125 parts of fermented composite fruit and vegetable powder, 6.25 parts of cartilage extract, 50 parts of marine fish collagen, 2.5 parts of red pomegranate powder, 2.5 parts of acerola cherry powder, 2.5 parts of tremella powder and 35 parts of fructo-oligosaccharide.
5. An oral composition with cosmetic function according to any one of claims 1-4, wherein said formulation is an oral formulation; the method comprises the following steps: granule, solid beverage, tablet, milk tablet, yogurt tablet, colostrum tablet, chewable tablet, honeyed pill, concentrated honeyed pill, water honeyed pill, concentrated water honeyed pill, oral liquid preparation, bagged tea, decocted tea, beverage, powder, sugar, medicated wine, and confection.
6. An oral composition with skin caring effect according to claim 5, wherein the preparation contains adjuvants besides active ingredients; the auxiliary materials comprise citric acid, stevioside, edible essence, natural menthol, strawberry essence, starch, mannitol, aspartame, magnesium stearate, xylitol and microcrystalline cellulose.
7. An oral composition with a skin caring function according to any one of claims 5-6, wherein the preparation comprises 40-90 parts of active ingredient and 10-60 parts of adjuvant by weight.
8. An oral composition with cosmetic function according to any one of claims 5-7, wherein the preparation process of the composition comprises: taking the formula amount of polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen peptide, red pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide, sieving, mixing, adding auxiliary materials, mixing uniformly, and preparing the required oral preparation according to the conventional process.
9. The oral composition with cosmetic function according to claim 8, wherein the solid beverage is prepared by: taking the formula amount of polished rice juice powder, micromolecular elastin peptide, fermented composite fruit and vegetable powder, cartilage extract, marine fish collagen peptide, red pomegranate powder, acerola cherry powder, tremella powder and fructo-oligosaccharide, sieving, mixing, adding auxiliary materials, mixing uniformly, and packaging to obtain the solid beverage.
CN202010434826.4A 2020-05-19 2020-05-19 An oral composition with skin caring effect, and its preparation method Pending CN111616354A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010434826.4A CN111616354A (en) 2020-05-19 2020-05-19 An oral composition with skin caring effect, and its preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010434826.4A CN111616354A (en) 2020-05-19 2020-05-19 An oral composition with skin caring effect, and its preparation method

Publications (1)

Publication Number Publication Date
CN111616354A true CN111616354A (en) 2020-09-04

Family

ID=72267206

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010434826.4A Pending CN111616354A (en) 2020-05-19 2020-05-19 An oral composition with skin caring effect, and its preparation method

Country Status (1)

Country Link
CN (1) CN111616354A (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109043548A (en) * 2018-08-21 2018-12-21 广州能靓生物技术有限公司 A kind of composition, beautifying face and moistering lotion, the product of anti-aging and application
CN109105690A (en) * 2018-09-18 2019-01-01 广州市爱百伊生物技术有限公司 A kind of fruity beverage and its processing method containing collagen peptide
CN109156829A (en) * 2018-09-12 2019-01-08 广州市顺芝堂生物科技有限公司 A kind of Isin glue collagen composition and its preparation method and application
CN109619578A (en) * 2018-11-15 2019-04-16 北京斯利安药业有限公司 Moisturizing is crease-resistant, the composition for improving skin elasticity and its preparation method and application
CN109619358A (en) * 2018-12-12 2019-04-16 中慈保健品科技开发有限公司 A kind of solid drinks and preparation method thereof based on soybean peptide albumen powder
CN110140844A (en) * 2019-06-16 2019-08-20 济南怡能食品科技有限公司 A kind of beautifying and youth-keeping beverage and its preparation method and application
CN111110833A (en) * 2019-12-23 2020-05-08 西安大重澳生物科技有限公司 A skin caring composition for oral administration and topical application, and its preparation method

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109043548A (en) * 2018-08-21 2018-12-21 广州能靓生物技术有限公司 A kind of composition, beautifying face and moistering lotion, the product of anti-aging and application
CN109156829A (en) * 2018-09-12 2019-01-08 广州市顺芝堂生物科技有限公司 A kind of Isin glue collagen composition and its preparation method and application
CN109105690A (en) * 2018-09-18 2019-01-01 广州市爱百伊生物技术有限公司 A kind of fruity beverage and its processing method containing collagen peptide
CN109619578A (en) * 2018-11-15 2019-04-16 北京斯利安药业有限公司 Moisturizing is crease-resistant, the composition for improving skin elasticity and its preparation method and application
CN109619358A (en) * 2018-12-12 2019-04-16 中慈保健品科技开发有限公司 A kind of solid drinks and preparation method thereof based on soybean peptide albumen powder
CN110140844A (en) * 2019-06-16 2019-08-20 济南怡能食品科技有限公司 A kind of beautifying and youth-keeping beverage and its preparation method and application
CN111110833A (en) * 2019-12-23 2020-05-08 西安大重澳生物科技有限公司 A skin caring composition for oral administration and topical application, and its preparation method

Similar Documents

Publication Publication Date Title
US5925348A (en) Methods utilizing compositions containing sacred lotus (methyltransferase) to treat aging skin
CN101116506B (en) Health products having functions of improving skin moisture
US20090257965A1 (en) Abnormal protein removing composition
US20080206175A1 (en) Composition for Skin Whitening and Wrinkle Improvement Comprising Vaccinium Uliginosum Extract and Method for Preparation Thereof
CN108271982A (en) A kind of Isin glue collagen peptide vegetable solid beverage and the preparation method and application thereof
KR102358623B1 (en) Food composition for improving skin condition comprising collagen peptide
KR101066676B1 (en) A oral composition for improving beauty of skin
KR101295368B1 (en) Composition for skin wrinkle improvement comprising extracts of honeybush extract or its fermentation solution as an active ingredient
JP2006219432A (en) Composition having rough skin-preventing activity, cosmetic and beverage
CN102973937A (en) Composition with skin beauty effect and oral administration cosmetic containing composition
WO2015015816A1 (en) Fibroblast activator
CN112674334A (en) Whitening, beautifying and anti-saccharification blueberry powder compound solid preparation as well as preparation method and application thereof
KR20120131065A (en) The composition comprising the extract or fraction of Pleurotus eryngii var. ferulae for prevention of anti aging as an active ingredient
JP2011055837A (en) Food and drink for beautification
CN111529474A (en) Multi-effect composition for moisturizing, whitening and antioxidant repair and preparation method and application thereof
KR20080090808A (en) Composition of healthy food for a skin
CN115486541B (en) Herbal probiotic composition with whitening effect and preparation method thereof
JPH09118626A (en) Medicine containing 'tencha' extract as active ingredient and food product and cosmetic containing the same
KR101738339B1 (en) Composition for improving skin aging and wrinkle comprising herbal medicine mixed extract as effective component
KR20080087941A (en) A composition containing the low molecular weight hyaluronic acid for improving skin wrinkles and skin peeling
CN111616354A (en) An oral composition with skin caring effect, and its preparation method
CN114128893A (en) Composition containing nicotinamide and glutathione and application thereof
JP2012067082A (en) Oral composition
JP2021187787A (en) Exosome secretagogue, exosome uptake promoter, exosome secretion-promoting beauty composition, and exosome secretion promoting method
CN111700818A (en) Wrinkle-removing and anti-aging ginseng polypeptide toning lotion and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination