CN101116506B - Health products having functions of improving skin moisture - Google Patents

Health products having functions of improving skin moisture Download PDF

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Publication number
CN101116506B
CN101116506B CN200710121206XA CN200710121206A CN101116506B CN 101116506 B CN101116506 B CN 101116506B CN 200710121206X A CN200710121206X A CN 200710121206XA CN 200710121206 A CN200710121206 A CN 200710121206A CN 101116506 B CN101116506 B CN 101116506B
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powder
health products
skin
collagen
moisture
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CN200710121206XA
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CN101116506A (en
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张永丽
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Beijing Baode Runsheng Pharmaceutical Medical Technology Development Co., Ltd.
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Beijing Increase Pharmaceutical Technology Co Ltd
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Abstract

The present invention relates to a health-care product capable of ameliorating water content of skin and the preparation method thereof. The active components contained in the product include pearl powder, collagen protein, extract of grape seed, and vitamin E powder. The present invention is to combine the raw materials as above reasonable and scientifically to produce an orally taken agent, which has convenient taking, and the capability to effectively ameliorate the water content of the skin as proved by the experiments.

Description

A kind of have health products that improve the moisture of skin function
Technical field
The present invention relates to the health food technology field, specifically a kind of health products that are used to improve moisture of skin.
Background technology
Skin is one of organ of human body maximum, 16% of about percentage of liveweight.Skin is divided into epidermis, corium, hypodermis.Epidermis is the of paramount importance part of skin, and the barrier protection effect of skin is mainly realized by epidermis.But its protective inner tissue avoids the infringement of foreign object and bacterium, prevents losing of things such as moisture, electrolyte in the body.Sebum is the main source of skin surface lipid, and it and water form emulsion, and the too fast evaporation of the moisture of prevention is arranged, and makes skin and hair keep soft and moist.Skin just can be kept healthy and beautiful if can keep grease and water balance.With regard to improving moisture of skin, more concern was cosmetics in the past, pursuit to beauty now trends towards " from outside to inside ", people begin to pay attention to inner adjusting, people are to building up health and can keeping the functional food of physiological functions such as beauty more to pay close attention to, and " dietotherapy " pursued by increasing people.
Summary of the invention
The object of the present invention is to provide a kind of moisture of skin of improvement health care foods that has, its preparation method is provided simultaneously.
The present invention is achieved by the following technical solutions:
A kind of have health products that improve the moisture of skin function, and its contained active component comprises: pearl powder, collagen, grape seed extract, vitamin E powder; By weight, the active component of making these health products is: pearl powder 0.5-2.5 part, collagen 10-20 part, grape seed extract 0.5-2.5 part, vitamin E powder 0.5-1.5 part; Preferably, by weight, the active component of making these health products is: pearl powder 1-2 part, collagen 12-18 part, grape seed extract 1-2 part, vitamin E powder 0.8-1.2 part; The active component optimum weight part of making these health products is: pearl powder 1.4-1.6 part, collagen 14-16 part, grape seed extract 1.4-1.6 part, vitamin E powder 0.9-1.1 part.
Preparation of the present invention is an oral formulations; Comprise: hard shell capsules, soft capsule, granule, tablet, milk sheet, sour milk tablet, colostrum sheet, chewable tablets, honeyed bolus, concentrated honeyed bolus, water-honeyed pill, condensed water honeyed bolus, oral liquid, packed medicinal tea, decoction medicinal tea, beverage, pulvis, carbohydrate, vina, preserved fruit.
Described preparation also comprises auxiliary material except that active component; By weight, active component accounts for 60-90 part, and auxiliary material accounts for 10-40 part.
The preparation technology of described health products comprises: get pearl powder, collagen, grape seed extract, vitamin E powder, pulverize, sieve, mix, add auxiliary material, technology is prepared into required oral formulations routinely.
Specifically, the preparation technology of tablet is: get pearl powder, collagen, grape seed extract, vitamin E powder, mix, sieve, add filler, mixing is granulated, and adds lubricant, mixing, and compressing tablet, dressing gets tablet.
Grape seed extract of the present invention can be commercially available or adopt following method to be prepared from: grape pip adds water or Different concentrations of alcohol is extracted, and concentrates drying; Or further adopt alcohol deposition method, water return in molten method, organic solvent extractionprocess, flocculent precipitation, the column chromatography one or more unite use carry out suitably refining after, pulverize, mix, sieve, check, grape seed extract; Wherein press dry product and calculate, the content of OPC must not be lower than 80%.
Among the present invention, pearl has delaying senility function, studies show that, the light base Europe squama amino acid that is contained in the pearl powder is a kind of special moistening composition, skin to the people has compatibility, can make skin recover original moist, can promote the thermal energy oxidation of Skin Cell to supply with, make intracellular movable upsweep, impel skin moistening, fine and smooth; Can repair damaged cell, promote the supply of nutrition, make coarse skin recover gloss, keep moistening; Can increase the skin blood circulation, suppress the growth of lipofuscin in the body, impel cell viability to increase, delaying cell aging promotes the regeneration of epidermal cell, makes the skin softness, and wrinkle, freckle are eliminated; Can regulate physiological function, promote people's bulk-growth, make the cellular-restoring vigor, thereby make skin have gloss.Collagen can be repaired injured tissue rapidly, promotes cell metabolism, increases the skin moisturizing ability, improves moistening effect, makes skin more apparent beautiful; Increase skin compactness and elasticity, less wrinkle produces; The secretion of adjustment skin oil and fat, the protection skin; Can make coarse skin recover level and smooth, increase the raw material supplying of making collagen, can promote the synthetic of collagen, allow skin reply strong hydratability and tension force, promote skin wound healing and surperficial self-sow, make skin recover young vigor.Can to promote that collagen forms appropriately crosslinked for the main active OPC in the grape seed extract, simultaneously as a kind of effective free radical scavenger, can prevent the generation of the unusual physiological situation of skin " excessively crosslinked ", thereby stoped the appearance of wrinkle of skin and vesica, kept the submissive smooth of skin; Vitamin E has stronger beautifying skin and anti-radical action, and OPC and vitamin E can reduce the destruction of radical pair collagen as antioxidant simultaneously, improves collagen in the absorption by human body utilization.
Health products of the present invention are regulated the scientifically assembly rationally of above-mentioned active component body-internal-circulation, thereby are reached the effect that improves skin moisture.
Below situation illustrates beneficial effect of the present invention by experiment:
Carry out human feeding trial, the moisture content of test forehead glabella skin.
Measure environment: spacious, ventilation condition is good, the inspection chamber that space environments such as temperature, humidity are stable carries out.Dip in distilled water with clean cotton balls and clean tested position under rest state, dry back mensuration of carrying out moisture content in 15 minutes, mensuration work is undertaken by same people before and after the test.
Experimenter's age is 30-50 year, skin moisture≤12.
The test-meal group: capsule of the present invention for oral administration, given the test agent gives 30 days time, and the experimenter does not change original eating habit at duration of test, normal diet, and must not take the cosmetics that other keeps the article of skin moisture and influences result's judgement.Test-meal number 50 people.
Control group: take placebo; Test-meal number 50 people.
Effective 45 people of result, invalid 5 people are measured in moisture of skin variation before and after the test-meal.
Result of the test shows that medicine of the present invention has the effect that improves skin moisture.
Concrete embodiment
Embodiment 1:
Pearl powder 37.5g, collagen 375g, grape seed extract 37.5g, vitamin E powder 25g, starch 123.2g, dolomol 1.8g
Pearl powder, collagen, grape seed extract, the vitamin E powder of getting recipe quantity mix, and sieve, and add the starch of recipe quantity, and mixing is granulated, and adds dolomol, and mixing is pressed into 1000, and dressing gets tablet.
Embodiment 2:
Pearl powder 12.5g, collagen 250g, grape seed extract 12.5g, vitamin E powder 12.5g, lactose 80g, microcrystalline cellulose 80g, talcum powder 2.5g
Pearl powder, collagen, grape seed extract, the vitamin E powder of getting recipe quantity mix, and sieve, and add lactose, microcrystalline cellulose, the talcum powder of recipe quantity, and mixing is granulated, and is encapsulated, gets capsule.
Embodiment 3:
Pearl powder 62.5g, collagen 500g, grape seed extract 62.5g, vitamin E powder 37.5g, pregelatinized starch 85g, superfine silica gel powder 2.5g
Get pearl powder, collagen, grape seed extract, the vitamin E powder mixing of recipe quantity, sieve, add the pregelatinized starch of recipe quantity, mixing adds superfine silica gel powder 2.5g, and mixing is granulated, and packing gets granule.
Embodiment 4:
Pearl powder 40g, collagen 400g, grape seed extract 40g, vitamin E powder 27.5g, sweet mellow wine 239.5g, aspartame 1.5g, dolomol 1.5g
Pearl powder, collagen, grape seed extract, the vitamin E powder of getting recipe quantity mix, and sieve, and add sweet mellow wine, aspartame, the dolomol of recipe quantity, and mixing is granulated, and drying is pressed into 1000, gets chewable tablets.
Embodiment 5:
Pearl powder 25g, collagen 300g, grape seed extract 25g, vitamin E powder 20g, calcium monohydrogen phosphate 65g, pregelatinized starch 65g
Pearl powder, collagen, grape seed extract, the vitamin E powder of getting recipe quantity mix, and sieve, and add calcium monohydrogen phosphate, the pregelatinized starch of recipe quantity, pulverize, and mixing, encapsulated, get capsule.
Embodiment 6:
Pearl powder 50g, collagen 450g, grape seed extract 50g, vitamin E powder 30g, xylitol 107g, talcum powder 13g
Pearl powder, collagen, grape seed extract, the vitamin E powder of getting recipe quantity mix, and sieve, and add the xylitol of recipe quantity, and mixing is granulated, and adds talcum powder, mixing, and compressing tablet gets tablet.
Embodiment 7:
Pearl powder 35g, collagen 350g, grape seed extract 35g, vitamin E powder 22.5g, microcrystalline cellulose 150g, stevioside glycosides 5g, talcum powder 2.5g
Pearl powder, collagen, grape seed extract, the vitamin E powder of getting recipe quantity mix, and sieve, and add microcrystalline cellulose, stevioside glycosides, the talcum powder of recipe quantity, pulverize, and mixing, packing gets granule.
Grape seed extract of the present invention is commercially available or adopts following method to prepare: grape pip adds water or Different concentrations of alcohol is extracted, and concentrates drying; Or further adopt alcohol deposition method, water return in molten method, organic solvent extractionprocess, flocculent precipitation, the column chromatography one or more unite use carry out suitably refining after, pulverize, mix, sieve, check, grape seed extract.By dry product, the content of OPC must not be lower than 80%.

Claims (6)

1. one kind has the health products that improve the moisture of skin function, it is characterized in that, calculate by weight, the active component of making these health products is: pearl powder 0.5-2.5 part, collagen 10-20 part, the content that calculates OPC by dry product are not less than grape seed extract 0.5-2.5 part, vitamin E powder 0.5-1.5 part of 80%.
2. a kind of health products that improve the moisture of skin function that have according to claim 1, it is characterized in that, calculate by weight, the active component of making these health products is: pearl powder 1-2 part, collagen 12-18 part, the content that calculates OPC by dry product are not less than grape seed extract 1-2 part, vitamin E powder 0.8-1.2 part of 80%.
3. a kind of health products that improve the moisture of skin function that have according to claim 2, it is characterized in that, calculate by weight, the active component of making these health products is: pearl powder 1.4-1.6 part, collagen 14-16 part, the content that calculates OPC by dry product are not less than grape seed extract 1.4-1.6 part, vitamin E powder 0.9-1.1 part of 80%.
4. according to each described a kind of health products that improve the moisture of skin function that have of claim 1-3, it is characterized in that these health products are made hard shell capsules, soft capsule, granule, tablet, honeyed bolus, oral liquid, packed medicinal tea, decocted the oral formulations of medicinal tea, pulvis, vina.
5. a kind of health products that improve the moisture of skin function that have according to claim 4 is characterized in that, described preparation by weight, active component 60-90 part, auxiliary material 10-40 part.
6. a kind of health products that improve the moisture of skin function that have according to claim 4, it is characterized in that: the preparation method of tablet is: get pearl powder, collagen, grape seed extract, vitamin E powder, mix, sieve, add filler, mixing is granulated, and adds lubricant, mixing, compressing tablet, dressing gets tablet.
CN200710121206XA 2007-08-31 2007-08-31 Health products having functions of improving skin moisture Active CN101116506B (en)

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Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101530608B (en) * 2008-09-04 2012-01-18 厦门金日制药有限公司 Composition with functions of resisting radiation and improving skin moisture
CN101361970B (en) * 2008-09-28 2011-08-24 成都自豪药业有限公司 Composition with beauty effect and health care efficacy and use thereof
CN101524320B (en) * 2009-04-17 2011-02-02 武汉名实生物医药科技有限责任公司 Compound preparation capable of freckle-removing, skin-whitening, moisture preservation and wrinkle-resistance
CN101653256B (en) * 2009-06-09 2012-06-13 厦门市丝浓食品有限公司 Producing method of health product capsule for beautifying face and moistering lotion
CN101861961B (en) * 2010-01-21 2011-12-28 海南京润珍珠生物技术股份有限公司 Pearl bone strengthening health-care product
CN102224870B (en) * 2011-05-12 2013-11-06 周成灿 Collagen smoked plum tea and preparation method thereof
CN103315305B (en) * 2012-03-23 2016-01-20 尹载胜 Rice cake composition containing fish scale collagen and edible plants extract and vermicelli composition
CN102742658B (en) * 2012-07-10 2013-08-28 陕西科技大学 Goat milk tablet for maintaining beauty and keeping young and preparation method of goat milk tablet
CN103005471B (en) * 2013-01-10 2013-12-04 三门峡山水方正生物科技有限公司 Healthcare capsule for improving skin moisture
CN103385844B (en) * 2013-07-24 2015-04-29 青岛蓝莓生物科技有限公司 Blueberry anthocyanin and collagen composition and preparation method thereof
CN104397686A (en) * 2014-11-07 2015-03-11 柳城县天地自然食品有限公司 Skincare health care product with pearls and preparation method thereof
CN105661538A (en) * 2016-01-09 2016-06-15 深圳爱易瑞科技有限公司 Collagen peptide powder and preparation method thereof
CN105852124A (en) * 2016-04-11 2016-08-17 林映津 Preparation method of anthocyanin-containing collagen
CN106174532A (en) * 2016-08-31 2016-12-07 成都润馨堂药业有限公司 A kind of have health-care solid preparation and the preparation method improving skin moisture
CN106490623A (en) * 2016-10-28 2017-03-15 芜湖市诺康生物科技有限公司 A kind of with the compositionss for improving moisture of skin function

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CN1709474A (en) * 2005-07-14 2005-12-21 杜越新 Cosmetic formulation for skin spot-eliminating, whitening and wrinkle-removing, and its preparing method
CN1833722A (en) * 2006-01-10 2006-09-20 张恩及 Health products for face care and body care
CN1965801A (en) * 2006-11-10 2007-05-23 浙江欧诗漫集团有限公司 Skin care product with pearl
CN101026965A (en) * 2004-06-25 2007-08-29 费诺森股份有限公司 Compositions suitable for treating cutaneous signs of aging

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CN101026965A (en) * 2004-06-25 2007-08-29 费诺森股份有限公司 Compositions suitable for treating cutaneous signs of aging
CN1709474A (en) * 2005-07-14 2005-12-21 杜越新 Cosmetic formulation for skin spot-eliminating, whitening and wrinkle-removing, and its preparing method
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CN1965801A (en) * 2006-11-10 2007-05-23 浙江欧诗漫集团有限公司 Skin care product with pearl

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Owner name: BEIJING BAODE RUNSHENG PHARMACEUTICAL MEDICAL TECH

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Free format text: CORRECT: ADDRESS; FROM: 100088 ROOM 3003, TOWER B, TIANCHENG TECHNOLOGY BUILDING, NO. 2, XINFENG STREET, DEWAI, XICHENG DISTRICT, BEIJING TO: 100088 ROOM 4002, TOWER B, TIANCHENG TECHNOLOGY BUILDING, NO. 2, XINFENG STREET, DEWAI, XICHENG DISTRICT, BEIJING

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Address after: 100088 Beijing city Xicheng District, New Street No. 2 Tiancheng Technology building block B room 4002

Patentee after: Beijing Baode Runsheng Pharmaceutical Medical Technology Development Co., Ltd.

Address before: 100088 Beijing city Xicheng District, New Street No. 2 Tiancheng Technology building block B room 3003

Patentee before: Beijing Increase Pharmaceutical Technology Co., Ltd.