CN111606883B - 基于戊二酰亚胺骨架的含硫化合物及其应用 - Google Patents

基于戊二酰亚胺骨架的含硫化合物及其应用 Download PDF

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CN111606883B
CN111606883B CN202010116398.0A CN202010116398A CN111606883B CN 111606883 B CN111606883 B CN 111606883B CN 202010116398 A CN202010116398 A CN 202010116398A CN 111606883 B CN111606883 B CN 111606883B
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thio
dione
piperidine
oxoisoindolin
amino
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CN111606883A (zh
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杨小宝
姜标
仇星
孙宁
孙仁红
刘林义
任超伟
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ShanghaiTech University
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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CN202010116398.0A 2019-02-25 2020-02-25 基于戊二酰亚胺骨架的含硫化合物及其应用 Active CN111606883B (zh)

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EP3778590A4 (en) * 2018-04-09 2021-12-22 ShanghaiTech University ANTI PROTEIN DEGRADATION COMPOUND, ANTITUMOR APPLICATION, INTERMEDIATE THEREOF, AND INTERMEDIATE USE
EP3820532A4 (en) * 2018-07-11 2022-04-06 H. Lee Moffitt Cancer Center & Research Institute, Inc. DIMERE IMMUNOMODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS
EP3932922A4 (en) 2019-02-25 2022-05-11 ShanghaiTech University SULPHUR-CONTAINING COMPOUND BASED ON A GLUTARIMIDE FRAMEWORK AND ITS USE
CN111747924B (zh) * 2019-03-29 2023-11-10 华东师范大学 一类来那度胺/泊马度胺类似物及其应用
WO2021023233A1 (zh) 2019-08-05 2021-02-11 上海科技大学 Egfr蛋白降解剂及其抗肿瘤应用
AU2021226514B2 (en) * 2020-02-25 2023-10-19 Shanghaitech University Glutarimide skeleton-based compounds and application thereof
CN114456173B (zh) * 2020-11-10 2023-09-19 江苏恒瑞医药股份有限公司 稠环基取代的环己二酰亚胺类衍生物、其制备方法及其在医药上的应用
WO2023025136A1 (zh) * 2021-08-27 2023-03-02 杭州格博生物医药有限公司 异吲哚啉酮化合物及其用途
CN118019736A (zh) * 2022-09-08 2024-05-10 标新生物医药科技(上海)有限公司 基于cereblon蛋白设计的分子胶化合物及其应用
WO2024064358A1 (en) * 2022-09-23 2024-03-28 Ifm Due, Inc. Compounds and compositions for treating conditions associated with sting activity
CN116284195B (zh) * 2023-02-08 2025-07-01 湖南欧亚药业有限公司 一种氟维司群的制备方法
CN117551057B (zh) * 2023-03-24 2026-04-10 浙江海正药业股份有限公司 苯并环类衍生物及其制备方法和用途
EP4722207A1 (en) * 2023-06-01 2026-04-08 Gluetacs Therapeutics (Shanghai) Co., Ltd. Oxoisoindolinyl-substituted tetrahydropyrimidinedione derivative and use thereof
WO2025016351A1 (zh) * 2023-07-14 2025-01-23 标新生物医药科技(上海)有限公司 基于硫代的戊二酰亚胺基异吲哚啉酮骨架的化合物及其应用
CN120787222A (zh) * 2024-02-04 2025-10-14 标新生物医药科技(上海)有限公司 基于取代的异吲哚啉酮新颖骨架化合物、含有其的双功能蛋白降解剂及它们的应用

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