CN111569021A - A topical medicinal liquid for treating acne, and its preparation method - Google Patents

A topical medicinal liquid for treating acne, and its preparation method Download PDF

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Publication number
CN111569021A
CN111569021A CN202010439387.6A CN202010439387A CN111569021A CN 111569021 A CN111569021 A CN 111569021A CN 202010439387 A CN202010439387 A CN 202010439387A CN 111569021 A CN111569021 A CN 111569021A
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parts
liquid medicine
root
treating acne
decocting
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贾晋科
贾一凡
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483—Gleditsia (locust)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external liquid medicine for treating acne and a preparation method thereof. Is prepared from rhubarb horsetails, mirabilite, Chinese honeylocust spine, red peony root, safflower, dandelion, baikal skullcap root, corktree bark, goldthread root, honeysuckle flower, flavescent sophora root, poria cocos, atractylodes rhizome and licorice root. The preparation method comprises placing the above raw materials in weight parts in casserole, adding 500ml of water, soaking for 1 hr, decocting with strong fire until water is boiling, decocting with slow fire until 100ml of medicinal liquid is obtained, and filtering to obtain topical medicinal liquid. The invention has the advantages of difficult relapse after treatment, obvious treatment effect, no injury to the body during treatment and no side effect.

Description

A topical medicinal liquid for treating acne, and its preparation method
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external liquid medicine for treating acne and a preparation method thereof.
Background
Acne is also called whelk, facial acne is whelk growing on the face, which is a common dermatosis and is commonly seen in teenagers, and the facial acne has no age limit.
Facial acne is of many types, and polymorphic skin lesions such as facial comedones, papules, pustules, nodules and the like are the main. The clinical manifestations are characterized by the polymorphous lesions of the face, such as acne, pimple, pustule, and nodule. Acne occurs in close relation to factors such as hyperseborrhea, blockage of pilosebaceous ducts, bacterial infection and inflammation. Acne is easy to occur, and because areas such as the face and the neck are very easy to contact bacteria in life and bacterial infection is not easy to stop, the acne is not easy to cure and long in course of disease, facial acne of people is easy to be frequently generated for a long time, and severe acne can be suppurative, so that the facial acne needs to be treated in time. It is particularly noted that skin care products are only an adjunct to acne. Common western medicine methods for treating acne include: sulfur, local hormone injection, vitamin acid, benzene peroxide and the like, but generally only treat the symptoms and the root causes, and once the medicine is stopped, the medicine is easy to repeat, has certain side effects, and cannot radically treat acne, whelk and the like.
Disclosure of Invention
Based on the above problems, the present invention aims to provide a liquid medicine for external use for treating acne. The invention also provides a preparation method of the external liquid medicine.
The technical scheme adopted by the invention for treating acne and whelk is as follows: an external liquid medicine for treating acne comprises the following components in parts by weight:
10-20 parts of rheum officinale, 30-50 parts of mirabilite, 20-30 parts of spina gleditsiae, 20-25 parts of red peony root, 15-25 parts of safflower, 20-30 parts of dandelion, 10-20 parts of scutellaria baicalensis, 15-25 parts of golden cypress, 10-20 parts of coptis chinensis, 20-30 parts of honeysuckle, 45-60 parts of sophora flavescens, 45-60 parts of rhizoma smilacis glabrae, 15-30 parts of rhizoma atractylodis and 20-25 parts of liquorice.
Preferably, the external liquid medicine for treating acne comprises the following components in parts by weight:
20 parts of rhubarb, 50 parts of mirabilite, 30 parts of spina gleditsiae, 20 parts of red peony root, 25 parts of safflower, 30 parts of dandelion, 20 parts of scutellaria baicalensis, 25 parts of golden cypress, 20 parts of coptis chinensis, 30 parts of honeysuckle, 50 parts of radix sophorae flavescentis, 60 parts of rhizoma smilacis glabrae, 25 parts of rhizoma atractylodis and 20 parts of liquorice.
The preparation method of the external liquid medicine for treating acne comprises the following steps: putting the raw materials in parts by weight into a marmite, adding 500ml of water, soaking for 1 hour, decocting with strong fire until the water is boiled, slowly decocting with slow fire until the liquid medicine is 100ml, and filtering to obtain the external liquid medicine.
The application method of the external liquid medicine for treating acne comprises the following steps: the external liquid medicine is soaked and applied by a medical cotton gauze piece, the skin is cleaned and then the liquid medicine is applied to an affected part twice a day, half an hour to one hour each time, one month is a treatment course, and one to three treatment courses are continuously used.
The pharmacological and medicinal properties of the components in the external liquid medicine are explained as follows:
rhubarb: bitter and cold, entering spleen, stomach, large intestine, liver and heart meridians, purging pathogenic accumulation, clearing heat and purging fire, removing toxic substance, resolving carbuncle, promoting blood circulation, and dispelling blood stasis, and can be used for treating heat-toxin and pyocutaneous disease.
Mirabilite: has effects in clearing away heat, relieving constipation, preventing and treating calculus, relieving swelling and pain, and relieving inflammation.
Spina gleditsiae: pungent and warm herbs enter liver and stomach, and have the actions of dispersing swelling and draining pus, so they are indicated for abscess, sores, ringworm and leprosy.
Red peony: clearing heat and cooling blood, and removing blood stasis and relieving pain.
Safflower: promoting blood circulation, dredging channels, removing blood stasis and relieving pain.
Dandelion: bitter, sweet and cold herbs enter liver and stomach meridians, and have the effects of clearing away heat and toxic materials and treating heat-toxin, swelling and sore and ulcer.
Scutellaria baicalensis: clearing away heat and toxic material, and eliminating dampness.
Phellodendron bark: unprocessed with the actions of purging fire, removing toxicity, clearing heat and drying dampness.
Coptis chinensis: clear heat and dry dampness, purge fire and remove toxicity.
Honeysuckle flower: clearing away heat and toxic material.
Flavescent sophora root: bitter and cold, entering heart, liver, kidney, large intestine and bladder meridians, and has the effects of clearing heat and drying dampness.
Glabrous greenbrier rhizome: detoxicating, removing dampness, and relaxing joints.
Rhizoma atractylodis: dry dampness and strengthen spleen, dispel wind and dispel cold.
Licorice root: ganping, which enters heart, lung, spleen and stomach meridians, is indicated for abscess, deep-rooted carbuncle and sore and has the action of removing toxicity. It also has the action of moderating the action of herbs and harmonizing all herbs. Sweet and cold in property, entering lung, stomach and large intestine meridians, and has the actions of clearing heat and removing toxicity.
The above medicines together have the effects of clearing heat, relieving exterior syndrome, promoting blood circulation, removing blood stasis, dredging meridian passage, and coordinating yin and yang. Thereby playing a good role in treating acne.
The invention has the advantages of difficult relapse after treatment, obvious treatment effect, no injury to the body during treatment and no side effect.
Detailed Description
Example 1
The external liquid medicine for treating acne comprises the following components in parts by weight:
20 parts of rhubarb, 50 parts of mirabilite, 30 parts of spina gleditsiae, 20 parts of red peony root, 25 parts of safflower, 30 parts of dandelion, 20 parts of scutellaria baicalensis, 25 parts of golden cypress, 20 parts of coptis chinensis, 30 parts of honeysuckle, 50 parts of radix sophorae flavescentis, 60 parts of rhizoma smilacis glabrae, 25 parts of rhizoma atractylodis and 20 parts of liquorice.
The preparation method of the external liquid medicine for treating acne comprises the following steps: putting the raw materials in parts by weight into a marmite, adding 500ml of water, soaking for 1 hour, decocting with strong fire until the water is boiled, slowly decocting with slow fire until the liquid medicine is 100ml, and filtering to obtain the external liquid medicine.
The application method of the external liquid medicine for treating acne comprises the following steps: the external liquid medicine is soaked and applied by a medical cotton gauze piece, the skin is cleaned and then the liquid medicine is applied to an affected part twice a day, half an hour to one hour each time, one month is a treatment course, and one to three treatment courses are continuously used.
Example 2
The external liquid medicine for treating acne comprises the following components in parts by weight:
10 parts of rhubarb, 30 parts of mirabilite, 20 parts of spina gleditsiae, 20 parts of red peony root, 15 parts of safflower, 20 parts of dandelion, 10 parts of scutellaria baicalensis, 15 parts of golden cypress, 10 parts of coptis chinensis, 20 parts of honeysuckle, 45 parts of radix sophorae flavescentis, 45 parts of rhizoma smilacis glabrae, 15 parts of rhizoma atractylodis and 20 parts of liquorice.
The preparation method of the external liquid medicine for treating acne comprises the following steps: putting the raw materials in parts by weight into a marmite, adding 500ml of water, soaking for 1 hour, decocting with strong fire until the water is boiled, slowly decocting with slow fire until the liquid medicine is 100ml, and filtering to obtain the external liquid medicine.
The procedure was as in example 1.
Example 3
The external liquid medicine for treating acne comprises the following components in parts by weight:
20 parts of rhubarb, 50 parts of mirabilite, 30 parts of spina gleditsiae, 25 parts of red peony root, 25 parts of safflower, 30 parts of dandelion, 20 parts of scutellaria baicalensis, 25 parts of golden cypress, 20 parts of coptis chinensis, 30 parts of honeysuckle, 60 parts of radix sophorae flavescentis, 60 parts of rhizoma smilacis glabrae, 30 parts of rhizoma atractylodis and 25 parts of liquorice.
The preparation method of the external liquid medicine for treating acne comprises the following steps: putting the raw materials in parts by weight into a marmite, adding 500ml of water, soaking for 1 hour, decocting with strong fire until the water is boiled, slowly decocting with slow fire until the liquid medicine is 100ml, and filtering to obtain the external liquid medicine.
The procedure was as in example 1.
Example 4
The external liquid medicine for treating acne comprises the following components in parts by weight:
15 parts of rhubarb, 40 parts of mirabilite, 25 parts of spina gleditsiae, 23 parts of red peony root, 20 parts of safflower, 25 parts of dandelion, 15 parts of scutellaria baicalensis, 20 parts of golden cypress, 15 parts of coptis chinensis, 25 parts of honeysuckle, 55 parts of radix sophorae flavescentis, 55 parts of rhizoma smilacis glabrae, 25 parts of rhizoma atractylodis and 22 parts of liquorice.
The preparation method of the external liquid medicine for treating acne comprises the following steps: putting the raw materials in parts by weight into a marmite, adding 500ml of water, soaking for 1 hour, decocting with strong fire until the water is boiled, slowly decocting with slow fire until the liquid medicine is 100ml, and filtering to obtain the external liquid medicine.
The procedure was as in example 1.
Description of the cases:
1. a certain amount of plum is 28 years old for a woman, Shanxi province and county people, diagnosis is carried out in 2019 within 04 months, the symptoms are seen as facial scattered papules, the forehead and lower lip parts are more, part of cysts have pus spots, and the pulse is slippery and rapid.
2. Certain populus, 25 years old female, huguan county, and 6-day-4-2019, the symptoms are that papules are covered on the face, the papules are red, most of the papules are blackheads, most of the papules have small pus spots on the tops and nodular cysts, the symptoms are not good because the acnes are serious and are afraid of the people who see the faces, the treatment is sought for many times, the effect is not good, so the diagnosis and treatment are performed at the position of the people, the pulse is smooth and rapid, the symptoms are caused by heat-toxicity stagnation, qi stagnation and blood stasis, rhubarb is reused, the firewood is drawn at the bottom of the kettle, the toxicity is directly discharged, the symptoms after five doses are reduced, and the disease is cured by decocting and.
3. Some certain cow, 24 years old, Changzhi city, Tun Xiu county, diagnosed in 2018 in 12 months and 31 days, has symptoms of cystic swelling and papules on the face, most of the diseases with pus spots, slippery and rapid pulse and surging, and the symptoms of dampness-heat in upper jiao, and can be cured after the recipe is used for more than one month.
The above are only 3 of hundreds of patients treated by the prescription. The proportion of patients treated by the prescription in clinic is large, after the patients use the prescription, the advantages of face acne disappearance, face smoothness, endocrine conditioning and the like of the patients are obtained according to sex, age, severity of symptoms and the like, the effective rate is more than eighty percent, improvement is more than eighty percent, and the cure rate is more than ninety percent.

Claims (3)

1. The external liquid medicine for treating acne is characterized by comprising the following components in parts by weight:
10-20 parts of rheum officinale, 30-50 parts of mirabilite, 20-30 parts of spina gleditsiae, 20-25 parts of red peony root, 15-25 parts of safflower, 20-30 parts of dandelion, 10-20 parts of scutellaria baicalensis, 15-25 parts of golden cypress, 10-20 parts of coptis chinensis, 20-30 parts of honeysuckle, 45-60 parts of sophora flavescens, 45-60 parts of rhizoma smilacis glabrae, 15-30 parts of rhizoma atractylodis and 20-25 parts of liquorice.
2. The external liquid medicine for treating acne according to claim 1, characterized by comprising the following components in parts by weight:
20 parts of rhubarb, 50 parts of mirabilite, 30 parts of spina gleditsiae, 20 parts of red peony root, 25 parts of safflower, 30 parts of dandelion, 20 parts of scutellaria baicalensis, 25 parts of golden cypress, 20 parts of coptis chinensis, 30 parts of honeysuckle, 50 parts of radix sophorae flavescentis, 60 parts of rhizoma smilacis glabrae, 25 parts of rhizoma atractylodis and 20 parts of liquorice.
3. The method for preparing a liquid medicine for external use for treating acne according to claim 1 or 2, characterized by comprising the steps of: putting the raw materials in parts by weight into a marmite, adding 500ml of water, soaking for 1 hour, decocting with strong fire until the water is boiled, slowly decocting with slow fire until the liquid medicine is 100ml, and filtering to obtain the external liquid medicine.
CN202010439387.6A 2020-05-22 2020-05-22 A topical medicinal liquid for treating acne, and its preparation method Pending CN111569021A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102657732A (en) * 2012-04-26 2012-09-12 王炳云 Soup containing rhubarb, skullcap, phellodendron, coptis root, wild chrysanthemum, dandelion and mirabilite for acne vulgaris
CN106237035A (en) * 2016-08-31 2016-12-21 洪雅县瓦屋山药业有限公司 A kind of Chinese medicine formula utilizing refined even treatment acne

Patent Citations (2)

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