CN111466448A - Preparation method of high-water-solubility fructus cannabis extract - Google Patents
Preparation method of high-water-solubility fructus cannabis extract Download PDFInfo
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- CN111466448A CN111466448A CN202010288582.3A CN202010288582A CN111466448A CN 111466448 A CN111466448 A CN 111466448A CN 202010288582 A CN202010288582 A CN 202010288582A CN 111466448 A CN111466448 A CN 111466448A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 14
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- 238000001694 spray drying Methods 0.000 claims abstract description 9
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- 238000010008 shearing Methods 0.000 claims description 37
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- 238000002156 mixing Methods 0.000 claims description 18
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- 239000002994 raw material Substances 0.000 claims description 11
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- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims description 10
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- 238000000265 homogenisation Methods 0.000 claims description 7
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 6
- 229920002774 Maltodextrin Polymers 0.000 claims description 6
- 239000005913 Maltodextrin Substances 0.000 claims description 6
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 6
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 6
- 229940035034 maltodextrin Drugs 0.000 claims description 6
- 235000012239 silicon dioxide Nutrition 0.000 claims description 6
- 239000000377 silicon dioxide Substances 0.000 claims description 6
- 229920002472 Starch Polymers 0.000 claims description 5
- 235000019698 starch Nutrition 0.000 claims description 5
- 239000008107 starch Substances 0.000 claims description 5
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000843 powder Substances 0.000 abstract description 10
- 239000007787 solid Substances 0.000 abstract description 8
- 239000000463 material Substances 0.000 abstract description 4
- 239000003921 oil Substances 0.000 description 11
- 235000019198 oils Nutrition 0.000 description 11
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 10
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 10
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- 238000004806 packaging method and process Methods 0.000 description 3
- 206010003210 Arteriosclerosis Diseases 0.000 description 2
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 2
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 2
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 2
- 208000011775 arteriosclerosis disease Diseases 0.000 description 2
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- 235000020778 linoleic acid Nutrition 0.000 description 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 2
- 229960004488 linolenic acid Drugs 0.000 description 2
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- 239000012265 solid product Substances 0.000 description 2
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- 241000894006 Bacteria Species 0.000 description 1
- 235000008697 Cannabis sativa Nutrition 0.000 description 1
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- 241000196324 Embryophyta Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000218231 Moraceae Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000037208 balanced nutrition Effects 0.000 description 1
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- 235000012000 cholesterol Nutrition 0.000 description 1
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- 239000008199 coating composition Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 235000004626 essential fatty acids Nutrition 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
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- 239000011669 selenium Substances 0.000 description 1
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- 235000013619 trace mineral Nutrition 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings or cooking oils characterised by ingredients other than fatty acid triglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
- A23D9/02—Other edible oils or fats, e.g. shortenings or cooking oils characterised by the production or working-up
- A23D9/04—Working-up
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
- B01J13/043—Drying and spraying
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- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a preparation method of a high water-solubility fructus cannabis extract, which is characterized in that the fructus cannabis oil is encapsulated by corresponding auxiliary materials and a spray drying method to obtain the high water-solubility fructus cannabis extract solid powder, and the high water-solubility fructus cannabis extract solid powder contains a certain fructus cannabis oil component, can ensure that the fructus cannabis oil is not easily oxidized, and improves the stability.
Description
Technical Field
The invention relates to the technical field of vegetable oil extraction and processing, in particular to a preparation method of a high-water-solubility fructus cannabis extract.
Background
The hemp seed is dry mature seed of Cannabis sativa L, a Moraceae plant, is distributed in northeast, North China, east China, south China and the like, has the effect of relaxing bowel, is usually used for blood deficiency and body fluid deficiency, and is rich in nutrition, the value of the hemp seed is mainly reflected in the balanced nutrition structure composition and reasonable component content ratio, the content of fatty acid in the hemp seed is 25% -45%, wherein unsaturated fatty acid accounts for more than 90%, the ratio of linoleic acid to linolenic acid is about 3: 1, the hemp seed oil is determined to have the best balance ratio of omega-3 to omega-6 essential fatty acid by World Health Organization (WHO) and United nationality Food and Agricultural Organization (FAO), the proportion is considered as the best proportion of normal metabolism of a human body, the hemp seed oil also contains a great amount of vitamin E and trace elements such as selenium, zinc, manganese, germanium and the like, and the A L A which is known as a plant brain oil, the hemp seed oil has the effects of preventing arteriosclerosis, preventing, moisturizing blood sugar, nourishing the brain, protecting the blood, reducing blood fat, reducing the heart and reducing the blood pressure of people, and protecting the eyesight, and reducing the blood fat, and reducing the weight.
At present, most of the hemp seed oil sold in the market is prepared by the traditional squeezing method, and the hemp seed oil prepared by the supercritical extraction method is also reported. However, because the hemp seed oil content is high, no matter the hemp seed oil is prepared by pressing or supercritical extraction method of the hemp seed or the hemp seed extract is prepared by the traditional extraction method, the application of the hemp seed oil is limited because the hemp seed oil with high content can not be dried into powder and can not be dissolved in water. Or extracting the residue to obtain fructus Cannabis extract powder, which contains no fructus Cannabis oil.
The hemp seed oil contains nine kinds of saturated fatty acids, including palmitic acid and stearic acid. There are ten unsaturated fatty acids, accounting for 86%. Unsaturated fatty acids are very important to human body, for example, they can reduce cholesterol and triglyceride content, reduce blood viscosity, improve blood microcirculation, and increase brain cell activity. Thus, the content of polyunsaturated fatty acids in edible oils is an important marker for assessing their nutritional levels. Linolenic acid, linoleic acid and the like in the hemp seed oil are important polyunsaturated fatty acids which are necessary for human bodies and cannot be synthesized by the human bodies. Because the hemp seed oil has high unsaturation degree, the problems of oxidation, rancidity and the like are easy to occur, thereby affecting the quality of the hemp seed oil. In general, solids are more stable than liquids, which are more easily oxidized, but hemp seed oil has a low melting point and cannot be dried to solids under normal conditions.
At present, the commercially available fructus cannabis products are mainly fructus cannabis oil, or fructus cannabis dregs after oil extraction are extracted to prepare fructus cannabis extract powder, but the fructus cannabis extract powder does not contain fructus cannabis oil components. Hemp seed oil is an oily component, cannot be dried into powder, and has poor water solubility, so that the application of the hemp seed oil is limited. And the hemp seed oil has high content of unsaturated fatty acid components, so that the problems of oxidation rancidity and the like are easy to occur, and the quality of the hemp seed oil is influenced.
Disclosure of Invention
The invention aims to provide a preparation method of a high-water-solubility fructus cannabis extract, which has the characteristics of environmental friendliness, simple process, convenience in operation, short period, high efficiency and the like.
The technical scheme of the invention is as follows:
a method for preparing a high water-soluble fructus cannabis extract comprises the following steps:
(2) preparing raw materials: the raw material components are as follows
(2) Preheating water to 38-45 ℃, taking part of water to dissolve the modified starch to prepare a modified starch solution, dissolving the rest water with maltodextrin, trehalose, highland barley β -glucan, vitamin C and silicon dioxide, and uniformly mixing the water with the modified starch solution;
(3) preheating the hemp seed oil to 38-45 ℃, and uniformly mixing the hemp seed oil with the vitamin E;
(4) mixing the homogeneous solutions obtained in the step 2 and the step 3, and carrying out high-speed shearing at the shearing speed of 28000rpm for 3 times, each time for 90s, and cooling to below 35 ℃ before each shearing;
(5) 3, homogenizing for 2 times under high pressure after shearing, wherein the pressure is 30MPa, and cooling to below 35 ℃ before high-pressure homogenization for each time;
(6) and 4, carrying out spray drying after homogenizing, and controlling the air inlet temperature to be 110-200 ℃ and the air outlet temperature to be 60-90 ℃ to obtain the high-water-solubility fructus cannabis extract.
Preferably, the modified starch is obtained by gelatinizing and performing enzymolysis on common starch.
Preferably, the raw material components are preferably:
preferably, in the step 6, the inlet air temperature is controlled to be 120 ℃, and the outlet air temperature is controlled to be 65 ℃.
Preferably, the β -glucan content of the highland barley β -glucan is more than 50%.
The invention also discloses the fructus cannabis extract prepared by the method, and the solubility of the fructus cannabis extract in water is more than 120 g/L.
The invention carries out microencapsulation and packaging on the hemp seed oil by a corresponding auxiliary material and a spray drying method to obtain the high water-solubility hemp seed extract solid powder, which not only contains a certain hemp seed oil component, but also can ensure that the hemp seed oil is not easy to be oxidized, and improves the stability, and the invention also contains vitamin C and vitamin E in the packaging formula of the hemp seed oil, thereby further improving the inoxidizability of the product of the invention.
Compared with the prior art, the technical scheme of the invention at least has the following beneficial effects:
firstly, good water solubility: because of the high content of oil in fructus cannabis, the fructus cannabis oil obtained by squeezing or fructus cannabis extract prepared by the traditional extraction method has poor water solubility. The invention uses water-soluble auxiliary materials to carry out microencapsulation and packaging on the fructus cannabis oil, thus obtaining the fructus cannabis extract with high water solubility.
Secondly, the catalyst is not easy to be oxidized and has good stability: the hemp seed oil has high content of unsaturated fatty acid components, and is easy to have the problems of oxidation rancidity and the like, thereby influencing the quality of the hemp seed oil. The hemp seed oil is coated to prepare the hemp seed extract solid powder, so that the hemp seed oil is not easy to oxidize, the stability is improved, and the coating formula of the hemp seed oil contains vitamin C and vitamin E, so that the oxidation resistance of the product is further improved.
The hemp seed oil has multiple effects of delaying arteriosclerosis, preventing cardiovascular and cerebrovascular diseases, preventing cancer, moistening dryness and lubricating intestines, nourishing heart and strengthening brain, reducing blood fat, blood pressure and blood sugar, reducing fat and losing weight, resisting bacteria and diminishing inflammation, protecting eyesight and the like.
Fourthly, the application range of the product is improved: because hemp seed oil is insoluble in water and cannot be dried to a solid, hemp seed oil cannot be used in beverages and solid products. According to the invention, the hemp seed oil is prepared into high-water-solubility solid powder through microencapsulation coating, so that the hemp seed oil can be applied to beverages and solid products.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
(1) The modified starch is obtained by gelatinizing and enzymolysis, the basic chemical structure of the starch is not changed, but the crystallinity of the starch is improved by enzymolysis while the gelatinization can reduce the starch, and the modified starch has the characteristics of strong adsorption capacity, more pores and the like.
(2) The hemp seed oil is preheated to 37 ℃, and is uniformly mixed with the vitamin E, and the content of unsaturated fatty acid in the hemp seed oil is 90.3 percent. Vitamin C and vitamin E are antioxidants, and can prevent two-phase (water phase and oil phase) materials from being oxidized in the processing process.
(3) Adding the homogeneous solution obtained in the step 1 and the step 2 into a shearing tank, mixing, and carrying out high-speed shearing, wherein the shearing speed is 28000rpm, shearing is carried out for 3 times, each time is 90s, and the temperature is cooled to 25 ℃ before each shearing.
(4) And 3, homogenizing for 2 times at a high pressure after shearing, wherein the pressure is 30MPa, and cooling to 25 ℃ before high-pressure homogenization for each time.
(5) And 4, carrying out spray drying after homogenizing, and controlling the air inlet temperature to be 115 ℃ and the air outlet temperature to be 65 ℃ to obtain the fructus cannabis extract with high water solubility, wherein the solubility of the fructus cannabis extract in water reaches 160 g/L.
The preparation raw materials comprise the following components in percentage by weight:
example 2
(1) Preheating water to 38 ℃, taking a proper amount of modified starch to dissolve the modified starch to prepare a modified starch solution, dissolving the rest water with maltodextrin, trehalose, highland barley β -glucan, vitamin C and silicon dioxide, and uniformly mixing the rest water with the modified starch solution.
(2) Preheating the hemp seed oil to 38 ℃, and uniformly mixing the hemp seed oil with the vitamin E, wherein the content of unsaturated fatty acid in the hemp seed oil is 91.6%.
(3) Adding the homogeneous solution obtained in the step 1 and the step 2 into a shearing tank, mixing, and carrying out high-speed shearing, wherein the shearing speed is 28000rpm, shearing is carried out for 3 times, each time is 90s, and the temperature is cooled to 28 ℃ before each shearing.
(4) And 3, homogenizing for 2 times at a high pressure after shearing, wherein the pressure is 30MPa, and cooling to 28 ℃ before high-pressure homogenization for each time.
(5) And 4, carrying out spray drying after homogenizing, and controlling the air inlet temperature to be 130 ℃ and the air outlet temperature to be 70 ℃ to obtain the fructus cannabis extract with high water solubility, wherein the solubility of the fructus cannabis extract in water reaches 165 g/L.
The preparation raw materials comprise the following components in percentage by weight:
example 3
(1) Preheating water to 39 ℃, taking a proper amount of modified starch to dissolve the modified starch to prepare a modified starch solution, dissolving the rest water with maltodextrin, trehalose, highland barley β -glucan, vitamin C and silicon dioxide, and uniformly mixing the water with the modified starch solution.
(2) Preheating the hemp seed oil to 39 ℃, and uniformly mixing the hemp seed oil with the vitamin E, wherein the content of unsaturated fatty acid in the hemp seed oil is 90.5%.
(3) Adding the homogeneous solution obtained in the step 1 and the step 2 into a shearing tank, mixing, and carrying out high-speed shearing at the shearing speed of 28000rpm for 3 times, each time for 90s, and cooling to 30 ℃ before each shearing.
(4) And 3, homogenizing for 2 times at a high pressure after shearing, wherein the pressure is 30MPa, and cooling to 30 ℃ before high-pressure homogenization for each time.
(5) And 4, carrying out spray drying after homogenizing, and controlling the air inlet temperature to be 150 ℃ and the air outlet temperature to be 75 ℃ to obtain the fructus cannabis extract with high water solubility, wherein the solubility of the fructus cannabis extract in water reaches 135 g/L.
The preparation raw materials comprise the following components in percentage by weight:
example 4
(1) Preheating water to 40 ℃, taking a proper amount of modified starch to dissolve the modified starch to prepare a modified starch solution, dissolving the rest water with maltodextrin, trehalose, highland barley β -glucan, vitamin C and silicon dioxide, and uniformly mixing the rest water with the modified starch solution.
(2) The hemp seed oil is preheated to 40 ℃, and is uniformly mixed with the vitamin E, and the content of unsaturated fatty acid in the hemp seed oil is 89.1 percent.
(3) Adding the homogeneous solution obtained in the step 1 and the step 2 into a shearing tank, mixing, and carrying out high-speed shearing, wherein the shearing speed is 28000rpm, shearing is carried out for 3 times, each time is 90s, and the temperature is cooled to 32 ℃ before each shearing.
(4) And 3, homogenizing for 2 times at a high pressure after shearing, wherein the pressure is 30MPa, and cooling to 32 ℃ before high-pressure homogenization for each time.
(5) And 4, carrying out spray drying after homogenizing, and controlling the air inlet temperature to be 180 ℃ and the air outlet temperature to be 80 ℃ to obtain the fructus cannabis extract with high water solubility, wherein the solubility of the fructus cannabis extract in water reaches 120 g/L.
The preparation raw materials comprise the following components in percentage by weight:
example 5
(1) Preheating water to 42 ℃, taking a proper amount of modified starch to dissolve the modified starch to prepare a modified starch solution, dissolving the rest water with maltodextrin, trehalose, highland barley β -glucan, vitamin C and silicon dioxide, and uniformly mixing the rest water with the modified starch solution.
(2) Preheating the hemp seed oil to 42 ℃, and uniformly mixing the hemp seed oil with the vitamin E, wherein the content of unsaturated fatty acid in the hemp seed oil is 92.4%.
(3) Adding the homogeneous solution obtained in the step 1 and the step 2 into a shearing tank, mixing, and carrying out high-speed shearing, wherein the shearing speed is 28000rpm, shearing is carried out for 3 times, each time is 90s, and the temperature is cooled to 35 ℃ before each shearing.
(4) And 3, homogenizing for 2 times at a high pressure after shearing, wherein the pressure is 30MPa, and cooling to 35 ℃ before high-pressure homogenization for each time.
(5) And 4, carrying out spray drying after homogenizing, and controlling the air inlet temperature to be 200 ℃ and the air outlet temperature to be 90 ℃ to obtain the fructus cannabis extract with high water solubility, wherein the solubility of the fructus cannabis extract in water reaches 125 g/L.
The preparation raw materials comprise the following components in percentage by weight:
the highly water-soluble hemp seed extracts prepared in examples 1 to 5 were subjected to various index tests, and the results are shown in Table 1.
Table 1 test results of various indexes
The test results show that the water solubility of the fructus cannabis extracts prepared in the examples 1-5 is very high and reaches more than 100 g/L, which shows that the fructus cannabis extracts prepared by the invention have very high water solubility, the surface oil rate is very low and is lower than 1%, which shows that the microcapsules prepared by the method can completely wrap the fructus cannabis oil, and the wrapping effect is good.
Claims (6)
1. A preparation method of a high water-solubility fructus cannabis extract is characterized by comprising the following steps:
(1) preparing raw materials: the raw material components are as follows
(2) Preheating water to 38-45 ℃, taking part of water to dissolve the modified starch to prepare a modified starch solution, dissolving the rest water with maltodextrin, trehalose, highland barley β -glucan, vitamin C and silicon dioxide, and uniformly mixing the water with the modified starch solution;
(3) preheating the hemp seed oil to 38-45 ℃, and uniformly mixing the hemp seed oil with the vitamin E;
(4) mixing the homogeneous solutions obtained in the step 2 and the step 3, and carrying out high-speed shearing at the shearing speed of 28000rpm for 3 times, each time for 90s, and cooling to below 35 ℃ before each shearing;
(5) 3, homogenizing for 2 times under high pressure after shearing, wherein the pressure is 30MPa, and cooling to below 35 ℃ before high-pressure homogenization for each time;
(6) and 4, carrying out spray drying after homogenizing, and controlling the air inlet temperature to be 110-200 ℃ and the air outlet temperature to be 60-90 ℃ to obtain the high-water-solubility fructus cannabis extract.
2. The preparation method according to claim 1, wherein the modified starch is obtained by gelatinizing and enzymatically hydrolyzing a common starch.
3. The preparation method according to claim 1, wherein the raw material components are preferably:
4. the method according to claim 1, wherein the inlet air temperature is controlled to 120 ℃ and the outlet air temperature is controlled to 65 ℃ in step 6.
5. The preparation method of claim 1, wherein β -glucan content in the highland barley β -glucan is more than 50%.
6. The hemp seed extract produced by the production method according to claims 1 to 5, wherein the solubility of the hemp seed extract in water is 120 g/L or more.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113951486A (en) * | 2021-11-01 | 2022-01-21 | 北京麦克基普健康科技有限公司 | Whole fructus cannabis powder and preparation method and application thereof |
| CN114711427A (en) * | 2020-12-22 | 2022-07-08 | 云南汉盟制药有限公司 | Microcapsule and preparation method and application thereof |
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