CN111436434A - Green environment-friendly peroxyacetic acid disinfectant as well as preparation method and application thereof - Google Patents
Green environment-friendly peroxyacetic acid disinfectant as well as preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a green environment-friendly peroxyacetic acid disinfectant as well as a preparation method and application thereof, belonging to the technical field of pharmaceutical chemicals. The invention provides a peroxyacetic acid disinfectant, which comprises the following raw materials: glacial acetic acid, hydrogen peroxide, citric acid, boric acid, sodium citrate and urea; the volume ratio of glacial acetic acid to hydrogen peroxide is 1-2: 1-3; the adding amount of the citric acid is 1-10% of the mass of the glacial acetic acid; the adding amount of the boric acid is 1-10% of the mass of the hydrogen peroxide; the adding amount of the sodium citrate is 0.1-0.3% of the total material mass; the adding amount of the urea is 0.1-0.2% of the total mass of the materials. The peroxyacetic acid disinfectant disclosed by the invention is simple to synthesize and operate, free of environmental pollution and industrial three wastes, has the characteristics of high efficiency and broad spectrum, can quickly kill bacteria, viruses, fungi and spores, and is a green, environment-friendly, nontoxic, harmless and residue-free environment-friendly disinfectant.
Description
Technical Field
The invention belongs to the technical field of pharmaceutical chemicals, and particularly relates to a green environment-friendly peroxyacetic acid disinfectant as well as a preparation method and application thereof.
Background
In the face of the emergent new coronavirus infection pneumonia epidemic situation, most medical material production enterprises can not normally produce during the traditional spring holiday of China, and the market supply is short. Especially for the novel coronavirus which is mainly spread by respiratory droplets, air blocking is an effective disinfection mode, but the high-efficiency air disinfectant has a narrow application range and high price at ordinary times, so that the dosage is increased rapidly under the emergency situation of new coronary pneumonia, and the contradiction between supply and demand of the market is obvious.
Peracetic acid is also called PAA, is an internationally recognized high-efficiency broad-spectrum environment-friendly disinfectant, has the advantages of high efficiency, broad spectrum, quick action, nontoxic decomposition products, no residue and the like, and is widely used for disinfection in the fields of aseptic medical institutions, medical instruments, food processing industry, household vegetable and fruit disinfection, livestock and poultry breeding industry and the like. The peroxyacetic acid is a strong oxidant, can achieve the effect of quickly killing bacteria, viruses, fungi and spores, can be used for air disinfection compared with the traditional chlorine-containing disinfectant and 75% alcohol, and does not have the risks of chlorine poisoning and high-concentration alcohol flammability. According to the scheme of diagnosis and treatment of pneumonia infected by novel coronavirus (trial fourth edition) published by Weijian Commission of China, peracetic acid (PAA) can effectively inactivate coronavirus such as SARS-CoV and MERS-CoV, and is also effective for the novel coronavirus in the whole world at this time.
At present, peroxyacetic acid is generally produced industrially by using hydrogen peroxide and glacial acetic acid as raw materials and concentrated sulfuric acid as a catalyst. However, the method has a serious problem that the use amount of the concentrated sulfuric acid catalyst is large, and the concentrated sulfuric acid catalyst inevitably remains in the product, on one hand, the residual concentrated sulfuric acid can continuously catalyze the synthesis and decomposition of the peroxyacetic acid, so that the product is easy to explode, leak and other accidents in the transportation or storage process, on the other hand, the residual concentrated sulfuric acid has strong corrosivity due to strong acidity, and the application of the disinfectant product in the fields of food processing machinery, medical instruments and the like is limited. Concentrated sulfuric acid is a homogeneous catalyst, has high catalytic efficiency, and is generally kept standing for a long time in actual production to avoid the danger that peroxyacetic acid and hydrogen peroxide are decomposed to cause explosion and the like due to rapid temperature rise caused by excessively high reaction speed; and when the outdoor environment temperature is higher in summer, the reaction is hard to control, the potential safety hazard is increased in the transportation process, and a manufacturer usually stops production. Therefore, the invention provides a new synthesis method, so that the peroxyacetic acid product system does not contain strong acidic substances such as sulfuric acid and the like, and has important practical significance.
CN201410216038.2 discloses a method for continuously synthesizing peroxyacetic acid by using acidic cation exchange resin or perfluorosulfonic acid resin as a catalyst, but the resin is easily deactivated by swelling under the strong oxidizing condition of the synthesis process, resulting in higher production cost.
CN201210132144.3 discloses a peroxyacetic acid solution without additives and a preparation method thereof, which needs to perform complex purification operations on common hydrogen peroxide and common glacial acetic acid to obtain high-purity hydrogen peroxide with the concentration of 30-70 wt% and high-purity glacial acetic acid with the concentration of more than or equal to 99.9%, and controls the concentration of metal ions and corresponding supporting equipment, so that the process operation is complex and is not beneficial to industrial production.
CN201410542587.9 discloses a high-concentration high-stability monoperoxyacetic acid disinfectant, which is composed of the following raw materials in percentage by weight: 71-73% of glacial acetic acid, 1-3% of hydroxyethylidene diphosphonic acid, 17-20% of hydrogen peroxide, 1-3% of sodium glucoheptonate and the balance of water; the preparation method comprises the following steps: adding glacial acetic acid and hydroxyethylidene diphosphonic acid into a reaction kettle, stirring for 5-15min at normal temperature and normal pressure, slowly adding sodium glucoheptonate at the temperature of not higher than 30 ℃, stirring until the solution is clear and transparent, standing for 7-10min, adding hydrogen peroxide, stirring for 10min at normal temperature and normal pressure to prepare a final solution, and curing for 7-10 days at the sealed condition of 27-30 ℃. The method needs to use expensive hydroxyethylidene diphosphonic acid and sodium glucoheptonate, which results in higher cost; in addition, it requires the use of hydrogen peroxide at a concentration greater than 50%, which results in a higher risk in the manufacturing process, and its peracetic acid concentration is high, which greatly increases the risk in transportation and storage.
CN201010158445 discloses a stable peroxyacetic acid disinfectant, which uses 26% -31.5% of hydrogen peroxide and 8% -15% of acetic acid to prepare the peroxyacetic acid disinfectant, and the peroxyacetic acid disinfectant is left for 30 days to obtain a final solution.
Therefore, the prior art has the defects of complex production process, high production cost, long reaction synthesis time, high and unstable peracetic acid concentration, certain food safety due to the added catalyst sulfuric acid and the stabilizer 8-hydroxyquinline, potential safety hazards such as explosion, leakage and the like easily generated in the transportation or storage process, and the adoption of the concentrated sulfuric acid catalyst belongs to a chemical product forcibly controlled by the state and is difficult to prove in production and use. Therefore, the invention provides a new alternative catalytic synthesis method, so that a peroxyacetic acid synthesis system does not contain strong acidic substances such as sulfuric acid and the like, and the production efficiency is improved, thereby having very important practical significance.
Disclosure of Invention
The invention aims to solve the technical problem of improving a high-efficiency, low-cost and environment-friendly process to replace the prior art for producing peroxyacetic acid disinfectant by adopting a concentrated sulfuric acid catalyst or other expensive reagents.
The invention aims to solve the technical problems and firstly provides a green environment-friendly peroxyacetic acid disinfectant, which comprises the following raw materials: glacial acetic acid, hydrogen peroxide, citric acid, boric acid, sodium citrate and urea; wherein, the volume ratio of glacial acetic acid to hydrogen peroxide is 1-2: 1-3; the adding amount of the citric acid is 1-5% of the mass of the glacial acetic acid; the adding amount of the boric acid is 1-5% of the mass of the hydrogen peroxide; the adding amount of the sodium citrate is 0.1-0.3% of the total material mass; the adding amount of the urea is 0.1-0.2% of the total mass of the materials.
In order to further increase the content of peracetic acid in the disinfectant and improve the disinfection and sterilization capacity, preferably, in the green environment-friendly peracetic acid disinfectant, the volume ratio of glacial acetic acid to hydrogen peroxide is 2: 1-3; the adding amount of the citric acid is 3-5% of the mass of the glacial acetic acid; the adding amount of the boric acid is 2-8% of the mass of the hydrogen peroxide.
In the green environment-friendly peroxyacetic acid disinfectant, the mass concentration of the glacial acetic acid is not less than 80%.
In the green environment-friendly peroxyacetic acid disinfectant, the mass concentration of the hydrogen peroxide is 28-37%.
The invention also provides a preparation method of the green environment-friendly peroxyacetic acid disinfectant, which comprises the following steps: taking the raw materials according to the proportion;
a. dissolving glacial acetic acid and citric acid for reaction to obtain a homogeneous phase A;
b. dissolving hydrogen peroxide and boric acid for reaction to obtain a homogeneous phase B;
c. and c, uniformly mixing the homogeneous phase A obtained in the step a and the homogeneous phase B obtained in the step B, adding sodium citrate and urea after reacting at normal temperature, uniformly stirring, and standing at normal temperature for reacting to obtain the peracetic acid disinfectant.
In the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step a, the reaction temperature is normal temperature-60 ℃.
Preferably, in the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step a, the reaction temperature is 40-60 ℃.
In the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step a, the reaction time is 20-30 minutes.
In the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step b, the reaction temperature is normal temperature-60 ℃.
Preferably, in the step b, the reaction temperature of the preparation method of the green environment-friendly peroxyacetic acid disinfectant is 40-60 ℃.
In the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step b, the reaction time is 20-30 minutes.
In the step c, the mode of mixing the homogeneous phase A and the homogeneous phase B is as follows: add homogeneous B to homogeneous a.
In the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step c, the homogeneous phase A and the homogeneous phase B are mixed and stirred for 20-30 minutes to be uniformly mixed.
In the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step c, the reaction time at normal temperature is 2-4 hours.
In the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step c, sodium citrate and urea are added and stirred for 20-30 minutes to be uniformly mixed.
In the preparation method of the green environment-friendly peroxyacetic acid disinfectant, in the step c, standing reaction is carried out for 24-72 hours at normal temperature.
The mass concentration of the peroxyacetic acid in the peroxyacetic acid disinfectant provided by the invention is 3-18%; meanwhile, the process conditions are optimized, and the mass concentration of the peroxyacetic acid in the obtained peroxyacetic acid disinfectant can reach 5-15%.
The invention has the beneficial effects that:
compared with the prior art, the synthesis process of the oxyacetic acid disinfectant has simple operation, no environmental pollution and no industrial three wastes, and belongs to a green environment-friendly disinfectant; avoids the adverse effects of secondary reaction, leakage, explosion, corrosion and the like caused by residual sulfuric acid in the peroxyacetic acid, is convenient for storage and transportation, and solves the technical problem of the traditional production of the peroxyacetic acid.
The peroxyacetic acid disinfectant has high efficiency and broad spectrum, can quickly kill bacteria, viruses, fungi and spores, and is a green, environment-friendly, nontoxic, harmless and residue-free environment-friendly disinfectant; can be widely used and disinfected in large-scale sudden public health events; the disinfection of stations, airports and various vehicles in public places of high-density crowds is conventional; special requirements for disinfection of places such as hospitals and medical waste; disinfecting customs import and export vehicles and the like; sterilizing a drinking water source and a water supply system; sterilizing a household cabinet and a toilet space; sterilizing the cultivation farm; marine product cultivation sterilization; disinfection of sports equipment and other consumer premises; disinfection of office places, cultural entertainment places and the like.
Detailed Description
Specifically, the green environment-friendly peroxyacetic acid disinfectant comprises the following raw materials: glacial acetic acid, hydrogen peroxide, citric acid, boric acid, sodium citrate and urea; wherein, the volume ratio of glacial acetic acid to hydrogen peroxide is 1-2: 1-3; the adding amount of the citric acid is 1-5% of the mass of the glacial acetic acid; the adding amount of the boric acid is 1-5% of the mass of the hydrogen peroxide; the adding amount of the sodium citrate is 0.1-0.3% of the total material mass; the adding amount of the urea is 0.1-0.2% of the total mass of the materials.
In order to further increase the content of peracetic acid in the disinfectant and improve the disinfection and sterilization capacity, preferably, the volume ratio of glacial acetic acid to hydrogen peroxide in the green environment-friendly peracetic acid disinfectant is 2: 1-3; the adding amount of the citric acid is 3-5% of the mass of the glacial acetic acid; the adding amount of the boric acid is 2-8% of the mass of the hydrogen peroxide.
When the green environment-friendly peroxyacetic acid disinfectant is prepared, the mass concentration of the used glacial acetic acid is not less than 80 percent; the mass concentration of the used hydrogen peroxide is 28-37%; citric acid and boric acid are used as catalysts, sodium citrate and urea are used as stabilizing agents, and the purity can be analytically pure or higher; the citric acid and boric acid should be used in amounts based on glacial acetic acid solution and hydrogen peroxide solution, and not on pure CH3COOH and H2O2Is taken as a basis.
The invention also provides a preparation method of the green environment-friendly peroxyacetic acid disinfectant, which comprises the following steps: taking the raw materials according to the proportion;
a. dissolving glacial acetic acid and citric acid for reaction to obtain a homogeneous phase A;
b. dissolving hydrogen peroxide and boric acid for reaction to obtain a homogeneous phase B;
c. and c, uniformly mixing the homogeneous phase A obtained in the step a and the homogeneous phase B obtained in the step B, adding sodium citrate and urea after reacting at normal temperature, uniformly stirring, and standing at normal temperature for reacting to obtain the peracetic acid disinfectant.
In order to solve the technical problem of the traditional peroxyacetic acid synthesis, the invention adopts the physical and chemical technology to select the composite weak acid to replace the concentrated sulfuric acid for catalysis, and the optimal catalytic synthesis technical parameters are explored through repeated tests. In the step a, glacial acetic acid and citric acid react at normal temperature to 60 ℃ to obtain acetic anhydride homogeneous phase A; in the step B, hydrogen peroxide and boric acid react at normal temperature to 60 ℃ to obtain an acidic hydrogen peroxide homogeneous phase B; in order to accelerate the reaction speed, the reaction temperature in the steps a and b is preferably 40-60 ℃, and the reaction is generally carried out for 20-30 min.
According to the physicochemical characteristics of the peroxyacetic acid synthesized by catalysis, citric acid and glacial acetic acid are selected, boric acid and hydrogen peroxide are dissolved in water, the two phases are enhanced, the peroxyacetic acid is rapidly synthesized by catalysis, and the synthesis is carried out by catalytic reaction for 24-72 hours. In order to further solve the problem of stability of the synthetic peroxyacetic acid and reduce corrosivity and irritation, the sodium citrate and the urea are selected and added according to the mass percentage concentration by combining the physical and chemical characteristics of the stabilizer, and the sodium citrate and urea composite stabilizer is superior to other stabilizers after repeated tests.
In step c, the mode of mixing the homogeneous phase A and the homogeneous phase B is as follows: adding the homogeneous phase B into the homogeneous phase A so that the hydrogen peroxide can fully react with the acetic acid and the generation amount of the peroxyacetic acid is increased. And mixing the homogeneous phase A and the homogeneous phase B, stirring for 20-30 minutes to mix uniformly, reacting for 2-4 hours at normal temperature, adding sodium citrate and urea, stirring for 20-30 minutes to mix uniformly, and finally standing for reacting for 24-72 hours at normal temperature to obtain the peroxyacetic acid disinfectant.
The peroxyacetic acid disinfectant provided by the invention has the advantages that the mass concentration of the peroxyacetic acid is 3-18%, preferably 5-15%, the concentration is lower than 20%, the peroxyacetic acid disinfectant is easy to store and transport, the safety performance is high, and the peroxyacetic acid disinfectant can be directly used for disinfection and can also be used after dilution.
The present invention is further illustrated by the following examples, which are not intended to limit the scope of the invention.
Example 1
Adding 99.0 wt% of glacial acetic acid 50m L into a round-bottom flask, adding 1 g of citric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate acetyl homogeneous phase A;
adding 30 wt% of hydrogen peroxide 50m L into a round-bottom flask, adding 1 g of boric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate an acidic hydrogen peroxide homogeneous phase B;
adding the homogeneous phase B into the homogeneous phase A, stirring for 20-30 minutes, and then reacting for 2-4 hours at normal temperature; adding a stabilizer sodium citrate (the addition amount is 0.1 percent of the total material mass) and a stabilizer urea (the addition amount is 0.1 percent of the total material mass), stirring for 20-30 minutes, and then standing and reacting for 24-72 hours at normal temperature to obtain an peracetic acid disinfectant; the mass concentration of the peroxyacetic acid is 5-12% by adopting the experimental technical specification of disinfection technical specification of classical method.
Example 2
Adding 99.0 wt% of glacial acetic acid 50m L into a round-bottom flask, adding 2 g of citric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate acetyl homogeneous phase A;
adding 100m L wt% of hydrogen peroxide into a round-bottom flask, adding 2 g of boric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate an acidic hydrogen peroxide homogeneous phase B;
adding the homogeneous phase B into the homogeneous phase A, stirring for 20-30 minutes, and then reacting for 2-4 hours at normal temperature; adding a stabilizer sodium citrate (the addition amount is 0.1 percent of the total material mass) and a stabilizer urea (the addition amount is 0.2 percent of the total material mass), stirring for 20-30 minutes, and then standing and reacting for 24-72 hours at normal temperature to obtain an peracetic acid disinfectant; the mass concentration of the peroxyacetic acid is 5-10% by adopting the experimental technical specification of disinfection technical specification of classical method.
Example 3
Adding 99.0 wt% of glacial acetic acid 50m L into a round-bottom flask, adding 3 g of citric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate acetyl homogeneous phase A;
adding 150m L wt% of hydrogen peroxide into a round-bottom flask, adding 3 g of boric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate an acidic hydrogen peroxide homogeneous phase B;
adding the homogeneous phase B into the homogeneous phase A, stirring for 20-30 minutes, and then reacting for 2-4 hours at normal temperature; adding a stabilizer sodium citrate (the addition amount is 0.2 percent of the total material mass) and a stabilizer urea (the addition amount is 0.1 percent of the total material mass), stirring for 20-30 minutes, and then standing and reacting for 24-72 hours at normal temperature to obtain an peracetic acid disinfectant; the mass concentration of the peroxyacetic acid is 4-10% by adopting the experimental technical specification of disinfection technical specification of classical method.
Example 4
Adding 99.0 wt% of glacial acetic acid 100m L into a round-bottom flask, adding 4 g of citric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate acetyl homogeneous phase A;
adding 30 wt% of hydrogen peroxide 50m L into a round-bottom flask, adding 4 g of boric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate an acidic hydrogen peroxide homogeneous phase B;
adding the homogeneous phase B into the homogeneous phase A, stirring for 30 minutes, and then reacting for 2-4 hours at normal temperature; adding a stabilizer sodium citrate (the adding amount is 0.2 percent of the total material mass) and a stabilizer urea (the adding amount is 0.2 percent of the total material mass); stirring for 20-30 minutes, and then standing and reacting for 24-72 hours at normal temperature to obtain an peracetic acid disinfectant; the mass concentration of the peroxyacetic acid is 8-14% by adopting the experimental technical specification of disinfection technical specification of classical method.
Example 5
Adding 99.0 wt% of glacial acetic acid 100m L into a round-bottom flask, adding 5 g of citric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate acetyl homogeneous phase A;
adding 150m L wt% of hydrogen peroxide into a round-bottom flask, adding 5 g of boric acid catalyst, heating to 40-60 ℃, stirring for 20-30 minutes, and reacting to generate an acidic hydrogen peroxide homogeneous phase B;
adding the homogeneous phase B into the homogeneous phase A, stirring for 30 minutes, and then reacting for 2-4 hours at normal temperature; adding a stabilizer sodium citrate (the adding amount is 0.3 percent of the total material mass) and a stabilizer urea (the adding amount is 0.2 percent of the total material mass); stirring for 30 minutes, and then standing and reacting for 72 hours at normal temperature to obtain an peracetic acid disinfectant; the mass concentration of the peroxyacetic acid is 6-12% by adopting the experimental technical specification of disinfection technical specification of classical method.
Example 6
1. Peroxyacetic acid content stability detection
The results of stability testing of the peroxyacetic acid disinfectant solutions obtained in examples 1 to 5 are shown in Table 1.
TABLE 1 stability of Peroxyacetic acid content
As can be seen from the data in Table 1, the invention adopts citric acid and boric acid as catalysts and sodium citrate and urea as stabilizers, which can replace the catalysis of sulfuric acid in the prior art to successfully synthesize the peroxyacetic acid disinfectant; in the embodiment, catalysts with different concentration ratios can play a role in catalyzing and synthesizing peroxyacetic acid, and the embodiments 4 and 5 have the best effect; meanwhile, the peroxyacetic acid disinfectant can be stored for a long time.
2. Detection of disinfection and sterilization effect of peracetic acid disinfectant
The peracetic acid disinfectant obtained in example 4 is used for corresponding dilution, and killing organisms such as bacterial propagules, bacterial spores and viruses, and the results are shown in tables 2-5.
TABLE 2 concentration and time of peroxyacetic acid to kill bacterial propagules
TABLE 3 killing effect of peracetic acid solution on spores
TABLE 4 virucidal effect of peracetic acid solution
| Peroxyacetic acid concentration mg/L | Action time/min | Killing virus species |
| 1000 | 120 | Can destroy the antigenicity of hepatitis B virus |
| 2000 | 4-5 | Poliovirus |
| 5000 | 15-30 | Can destroy the antigenicity of hepatitis B virus |
TABLE 5 kill time of different concentrations of peracetic acid solutions against fungi
Experiments show that the peroxyacetic acid disinfectant has strong killing effect on bacteria propagules, bacteria spores, viruses and other organisms, and can kill the bacteria in a short time.
Claims (10)
1. The green environment-friendly peroxyacetic acid disinfectant is characterized in that: comprises the following raw materials: glacial acetic acid, hydrogen peroxide, citric acid, boric acid, sodium citrate and urea; wherein, the volume ratio of glacial acetic acid to hydrogen peroxide is 1-2: 1-3; the adding amount of the citric acid is 1-10% of the mass of the glacial acetic acid; the adding amount of the boric acid is 1-10% of the mass of the hydrogen peroxide; the adding amount of the sodium citrate is 0.1-0.3% of the total material mass; the adding amount of the urea is 0.1-0.2% of the total mass of the materials.
2. The green and environment-friendly peroxyacetic acid disinfectant as claimed in claim 1, wherein: the volume ratio of the glacial acetic acid to the hydrogen peroxide is 2: 1-3; the adding amount of the citric acid is 3-5% of the mass of the glacial acetic acid; the adding amount of the boric acid is 2-8% of the mass of the hydrogen peroxide.
3. The green and environment-friendly peroxyacetic acid disinfectant as claimed in claim 1, wherein: the mass concentration of the glacial acetic acid is not less than 80%.
4. The green and environment-friendly peroxyacetic acid disinfectant as claimed in any one of claims 1 to 3, wherein: the mass concentration of the hydrogen peroxide is 28-37%.
5. The method for preparing the green and environment-friendly peroxyacetic acid disinfectant as claimed in any one of claims 1 to 4, which is characterized in that: the method comprises the following steps: taking the raw materials according to the proportion;
a. mixing glacial acetic acid and citric acid for reaction to obtain a homogeneous phase A;
b. mixing hydrogen peroxide and boric acid for reaction to obtain a homogeneous phase B;
c. and c, uniformly mixing the homogeneous phase A obtained in the step a and the homogeneous phase B obtained in the step B, adding sodium citrate and urea after reacting at normal temperature, uniformly stirring, and standing at normal temperature for reacting to obtain the peracetic acid disinfectant.
6. The method for preparing the environment-friendly peroxyacetic acid disinfectant as claimed in claim 5, wherein: in the step a, the reaction temperature is normal temperature-60 ℃; preferably 40-60 ℃; the reaction time is 20-30 minutes.
7. The method for preparing the environment-friendly peroxyacetic acid disinfectant as claimed in claim 5, wherein: in the step b, the reaction temperature is normal temperature-60 ℃; preferably 40-60 ℃; the reaction time is 20-30 minutes.
8. The method for preparing the environment-friendly peroxyacetic acid disinfectant as claimed in claim 5, wherein: in step c, at least one of the following is satisfied:
the mode of mixing homogeneous phase A and homogeneous phase B is as follows: adding homogeneous phase B to homogeneous phase A;
mixing the homogeneous phase A and the homogeneous phase B, and stirring for 20-30 minutes to mix uniformly;
after the homogeneous phase A and the homogeneous phase B are uniformly mixed, the reaction time at normal temperature is 2-4 hours;
adding sodium citrate and urea, and stirring for 20-30 minutes to mix uniformly;
and adding sodium citrate and urea, uniformly stirring, and standing at normal temperature for 24-72 hours.
9. The preparation method of the green environment-friendly peroxyacetic acid disinfectant as claimed in claims 5 to 8, which is characterized in that: the mass concentration of the peroxyacetic acid in the obtained peroxyacetic acid disinfectant is 3-18%; preferably 5 to 15%.
10. The green and environment-friendly peroxyacetic acid disinfectant as defined in any one of claims 1-4 and the green and environment-friendly peroxyacetic acid disinfectant prepared by any one of claims 5-9 are used for disinfection and sterilization.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113729039A (en) * | 2021-08-27 | 2021-12-03 | 上海罗克环控节能科技股份有限公司 | Green environment-friendly disinfectant and preparation method thereof |
| CN115669662A (en) * | 2022-11-21 | 2023-02-03 | 成都科宏达科技有限公司 | Low-irritation stable monoperoxyacetic acid disinfectant and preparation method thereof |
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| CN115669662A (en) * | 2022-11-21 | 2023-02-03 | 成都科宏达科技有限公司 | Low-irritation stable monoperoxyacetic acid disinfectant and preparation method thereof |
| CN115669662B (en) * | 2022-11-21 | 2024-04-30 | 成都科宏达科技有限公司 | Low-irritation-stability unitary peroxyacetic acid disinfectant and preparation method thereof |
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