CN111183220B - 用于聚糖分析的工具 - Google Patents

用于聚糖分析的工具 Download PDF

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Publication number
CN111183220B
CN111183220B CN201880050240.9A CN201880050240A CN111183220B CN 111183220 B CN111183220 B CN 111183220B CN 201880050240 A CN201880050240 A CN 201880050240A CN 111183220 B CN111183220 B CN 111183220B
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Chinese (zh)
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CN111183220A (zh
Inventor
弗雷德里克·里奥
罗尔夫·卢德
史蒂芬·比约克
马林·梅贾尔
弗雷德里克·奥尔森
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Genovis AB
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Genovis AB
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Priority claimed from GBGB1708476.5A external-priority patent/GB201708476D0/en
Priority claimed from GBGB1708471.6A external-priority patent/GB201708471D0/en
Priority claimed from GBGB1806655.5A external-priority patent/GB201806655D0/en
Application filed by Genovis AB filed Critical Genovis AB
Publication of CN111183220A publication Critical patent/CN111183220A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24057—O-Sialoglycoprotein endopeptidase (3.4.24.57), i.e. glycoprotease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/952—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from bacteria

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CN201880050240.9A 2017-05-26 2018-05-25 用于聚糖分析的工具 Active CN111183220B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB1708476.5 2017-05-26
GB1708471.6 2017-05-26
GBGB1708476.5A GB201708476D0 (en) 2017-05-26 2017-05-26 Tools for glycan analysis
GBGB1708471.6A GB201708471D0 (en) 2017-05-26 2017-05-26 Polypeptide
GBGB1806655.5A GB201806655D0 (en) 2018-04-24 2018-04-24 Polypeptide
GB1806655.5 2018-04-24
PCT/EP2018/063833 WO2018215657A1 (en) 2017-05-26 2018-05-25 Enzymes for glycan analysis

Publications (2)

Publication Number Publication Date
CN111183220A CN111183220A (zh) 2020-05-19
CN111183220B true CN111183220B (zh) 2024-03-22

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CN201880050240.9A Active CN111183220B (zh) 2017-05-26 2018-05-25 用于聚糖分析的工具
CN201880050251.7A Active CN111183221B (zh) 2017-05-26 2018-05-25 用于o-糖蛋白的蛋白酶和结合多肽

Family Applications After (1)

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CN201880050251.7A Active CN111183221B (zh) 2017-05-26 2018-05-25 用于o-糖蛋白的蛋白酶和结合多肽

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US (3) US12448614B2 (enExample)
EP (2) EP3630968B8 (enExample)
JP (3) JP2020521460A (enExample)
KR (2) KR102608876B1 (enExample)
CN (2) CN111183220B (enExample)
AU (2) AU2018272984B2 (enExample)
CA (2) CA3063828A1 (enExample)
DK (2) DK3630967T3 (enExample)
ES (2) ES2986557T3 (enExample)
FI (2) FI3630968T3 (enExample)
IL (2) IL270950B2 (enExample)
PL (2) PL3630968T3 (enExample)
PT (2) PT3630968T (enExample)
WO (2) WO2018215657A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL270950B2 (en) * 2017-05-26 2025-06-01 Genovis Ab Tools for glycan analysis
CN114258431A (zh) * 2019-07-03 2022-03-29 帕利昂制药有限公司 重组人唾液酸酶、唾液酸酶融合蛋白及其使用方法
CN112795583A (zh) * 2020-11-16 2021-05-14 上海大学 重组唾液酸外切酶的制备方法、表达基因、重组表达载体及构建方法
AU2022413663A1 (en) * 2021-12-15 2024-06-13 Danisco Us Inc. Compositions and methods involving proteases specific for mannose-modified proteins
KR20250115409A (ko) * 2022-11-28 2025-07-30 암젠 인크 에타너셉트를 프로세싱하는 방법

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101426906A (zh) * 2004-09-10 2009-05-06 房芳 一类新颖的以蛋白质为基础的治疗用分子

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US6720165B2 (en) 2001-06-14 2004-04-13 Zyomix, Inc. Methods for making antibody fragments and compositions resulting therefrom
GB0624874D0 (en) 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
US8969034B2 (en) 2008-04-18 2015-03-03 New England Biolabs, Inc. Endoglycosidases that cleave O-linked glycans
EP2166085A1 (en) 2008-07-16 2010-03-24 Suomen Punainen Risti Veripalvelu Divalent modified cells
WO2010111686A2 (en) * 2009-03-27 2010-09-30 Life Technologies Corp Labeled enzyme compositions, methods & systems
GB201115841D0 (en) 2011-09-13 2011-10-26 Genovis Ab Protein and method
GB201316744D0 (en) 2013-09-20 2013-11-06 Genovis Ab Method
US10080787B2 (en) 2014-07-02 2018-09-25 New England Biolabs, Inc. Universal N-glycan binding reagent
WO2017052433A1 (en) 2015-09-24 2017-03-30 Saab Ab A modular fluid actuator system
US12006530B2 (en) 2016-02-04 2024-06-11 Genovis Ab Streptococcal proteases
IL270950B2 (en) * 2017-05-26 2025-06-01 Genovis Ab Tools for glycan analysis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101426906A (zh) * 2004-09-10 2009-05-06 房芳 一类新颖的以蛋白质为基础的治疗用分子

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Biochemical characterisation of the neuraminidase pool of the human gut symbiont Akkermansia muciniphila;Kun Huang et al.;《Carbohydrate Research》;第415卷;第16页图1 *
Identification and Characterization of Protein Glycosylation using Specific Endo- and Exoglycosidases;Magnelli, P.E et al.;《J. Vis. Exp.》;第58卷;第1页摘要 *
糖蛋白的研究进展;郭慧等;《生物技术通报》(第undefined期);第16-19页 *

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Publication number Publication date
EP3630967A1 (en) 2020-04-08
KR102608876B1 (ko) 2023-11-30
WO2018215656A1 (en) 2018-11-29
IL270950A (en) 2020-01-30
AU2018272400B2 (en) 2024-06-13
JP7195008B2 (ja) 2022-12-23
FI3630967T3 (fi) 2024-08-12
US20200087643A1 (en) 2020-03-19
AU2018272984B2 (en) 2024-05-23
IL270949B2 (en) 2025-06-01
EP3630967B1 (en) 2024-06-12
DK3630968T3 (da) 2024-07-29
PT3630967T (pt) 2024-08-21
IL270949B1 (en) 2025-02-01
KR102609790B1 (ko) 2023-12-04
WO2018215657A1 (en) 2018-11-29
US12448614B2 (en) 2025-10-21
EP3630968B8 (en) 2024-07-03
JP2023103233A (ja) 2023-07-26
JP2020522242A (ja) 2020-07-30
ES2986910T3 (es) 2024-11-13
AU2018272400A1 (en) 2019-12-05
EP3630968A1 (en) 2020-04-08
US11584922B2 (en) 2023-02-21
CA3063828A1 (en) 2018-11-29
FI3630968T3 (fi) 2024-07-24
CN111183221A (zh) 2020-05-19
PT3630968T (pt) 2024-07-30
JP7557896B2 (ja) 2024-09-30
ES2986557T3 (es) 2024-11-11
IL270950B2 (en) 2025-06-01
CA3063815A1 (en) 2018-11-29
IL270949A (en) 2020-01-30
AU2018272984A1 (en) 2019-12-05
EP3630968B1 (en) 2024-05-29
KR20200010322A (ko) 2020-01-30
JP2020521460A (ja) 2020-07-27
DK3630967T3 (da) 2024-08-19
US20230212543A1 (en) 2023-07-06
KR20200011955A (ko) 2020-02-04
PL3630967T3 (pl) 2024-11-18
WO2018215657A9 (en) 2019-03-14
CN111183221B (zh) 2024-04-09
US20200172889A1 (en) 2020-06-04
PL3630968T3 (pl) 2024-10-07
EP3630967B8 (en) 2024-07-17
WO2018215656A9 (en) 2019-03-14
CN111183220A (zh) 2020-05-19
IL270950B1 (en) 2025-02-01

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