DK3630967T3 - Protease og bindingspolypeptid for o-glycoproteiner - Google Patents

Protease og bindingspolypeptid for o-glycoproteiner Download PDF

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Publication number
DK3630967T3
DK3630967T3 DK18728576.2T DK18728576T DK3630967T3 DK 3630967 T3 DK3630967 T3 DK 3630967T3 DK 18728576 T DK18728576 T DK 18728576T DK 3630967 T3 DK3630967 T3 DK 3630967T3
Authority
DK
Denmark
Prior art keywords
glycoproteins
protease
binding polypeptide
polypeptide
binding
Prior art date
Application number
DK18728576.2T
Other languages
Danish (da)
English (en)
Inventor
Fredrik Leo
Stephan Bjork
Malin Mejare
Fredrik Olsson
Rolf Lood-Alayón
Original Assignee
Genovis Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1708471.6A external-priority patent/GB201708471D0/en
Priority claimed from GBGB1708476.5A external-priority patent/GB201708476D0/en
Priority claimed from GBGB1806655.5A external-priority patent/GB201806655D0/en
Application filed by Genovis Ab filed Critical Genovis Ab
Application granted granted Critical
Publication of DK3630967T3 publication Critical patent/DK3630967T3/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24057—O-Sialoglycoprotein endopeptidase (3.4.24.57), i.e. glycoprotease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/952—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from bacteria

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
DK18728576.2T 2017-05-26 2018-05-25 Protease og bindingspolypeptid for o-glycoproteiner DK3630967T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1708471.6A GB201708471D0 (en) 2017-05-26 2017-05-26 Polypeptide
GBGB1708476.5A GB201708476D0 (en) 2017-05-26 2017-05-26 Tools for glycan analysis
GBGB1806655.5A GB201806655D0 (en) 2018-04-24 2018-04-24 Polypeptide
PCT/EP2018/063832 WO2018215656A1 (en) 2017-05-26 2018-05-25 Protease and binding polypeptide for o-glycoproteins

Publications (1)

Publication Number Publication Date
DK3630967T3 true DK3630967T3 (da) 2024-08-19

Family

ID=62492612

Family Applications (2)

Application Number Title Priority Date Filing Date
DK18728576.2T DK3630967T3 (da) 2017-05-26 2018-05-25 Protease og bindingspolypeptid for o-glycoproteiner
DK18728577.0T DK3630968T3 (da) 2017-05-26 2018-05-25 Enzymer til glycananalyse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK18728577.0T DK3630968T3 (da) 2017-05-26 2018-05-25 Enzymer til glycananalyse

Country Status (14)

Country Link
US (3) US11584922B2 (enExample)
EP (2) EP3630968B8 (enExample)
JP (3) JP7195008B2 (enExample)
KR (2) KR102609790B1 (enExample)
CN (2) CN111183220B (enExample)
AU (2) AU2018272400B2 (enExample)
CA (2) CA3063815A1 (enExample)
DK (2) DK3630967T3 (enExample)
ES (2) ES2986910T3 (enExample)
FI (2) FI3630967T3 (enExample)
IL (2) IL270950B2 (enExample)
PL (2) PL3630968T3 (enExample)
PT (2) PT3630968T (enExample)
WO (2) WO2018215657A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3630968B8 (en) 2017-05-26 2024-07-03 Genovis AB Enzymes for glycan analysis
JP7462560B2 (ja) 2018-01-03 2024-04-05 パレオン ファーマシューティカルズ インコーポレイテッド 組換えヒトシアリダーゼ、シアリダーゼ融合タンパク質およびそれらの使用方法
AU2020301037B2 (en) * 2019-07-03 2026-08-06 Palleon Pharmaceuticals Inc. Recombinant human sialidases, sialidase fusion proteins, and methods of using the same
CN112795583A (zh) * 2020-11-16 2021-05-14 上海大学 重组唾液酸外切酶的制备方法、表达基因、重组表达载体及构建方法
EP4448782A1 (en) * 2021-12-15 2024-10-23 Danisco US Inc. Compositions and methods involving proteases specific for mannose-modified proteins
KR20250115409A (ko) * 2022-11-28 2025-07-30 암젠 인크 에타너셉트를 프로세싱하는 방법
US20260092921A1 (en) 2024-09-27 2026-04-02 Roche Diagnostics Gmbh Mutated neuroaminidase

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720165B2 (en) 2001-06-14 2004-04-13 Zyomix, Inc. Methods for making antibody fragments and compositions resulting therefrom
US7807174B2 (en) * 2002-11-22 2010-10-05 Nexbio, Inc. Class of therapeutic protein based molecules
GB0624874D0 (en) 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
WO2009129086A2 (en) 2008-04-18 2009-10-22 New England Biolabs, Inc. Endoglycosidases that cleave o-linked glycans
EP2166085A1 (en) 2008-07-16 2010-03-24 Suomen Punainen Risti Veripalvelu Divalent modified cells
WO2010111674A2 (en) * 2009-03-27 2010-09-30 Life Technologies Corporation Methods and apparatus for single molecule sequencing using energy transfer detection
GB201115841D0 (en) 2011-09-13 2011-10-26 Genovis Ab Protein and method
GB201316744D0 (en) 2013-09-20 2013-11-06 Genovis Ab Method
WO2016003795A1 (en) 2014-07-02 2016-01-07 New England Biolabs, Inc. Universal n-glycan binding reagent
WO2017052433A1 (en) 2015-09-24 2017-03-30 Saab Ab A modular fluid actuator system
AU2017214441B2 (en) 2016-02-04 2021-08-19 Genovis Ab New Streptococcal proteases
EP3630968B8 (en) * 2017-05-26 2024-07-03 Genovis AB Enzymes for glycan analysis

Also Published As

Publication number Publication date
EP3630968A1 (en) 2020-04-08
WO2018215657A1 (en) 2018-11-29
CN111183220B (zh) 2024-03-22
US11584922B2 (en) 2023-02-21
US12448614B2 (en) 2025-10-21
AU2018272400A1 (en) 2019-12-05
WO2018215657A9 (en) 2019-03-14
US20200087643A1 (en) 2020-03-19
WO2018215656A9 (en) 2019-03-14
JP2023103233A (ja) 2023-07-26
AU2018272400B2 (en) 2024-06-13
KR102608876B1 (ko) 2023-11-30
EP3630968B8 (en) 2024-07-03
IL270949B1 (en) 2025-02-01
US20200172889A1 (en) 2020-06-04
FI3630968T3 (fi) 2024-07-24
CN111183221B (zh) 2024-04-09
IL270950A (en) 2020-01-30
EP3630967A1 (en) 2020-04-08
ES2986557T3 (es) 2024-11-11
DK3630968T3 (da) 2024-07-29
AU2018272984B2 (en) 2024-05-23
EP3630968B1 (en) 2024-05-29
IL270950B2 (en) 2025-06-01
KR20200010322A (ko) 2020-01-30
CA3063815A1 (en) 2018-11-29
KR102609790B1 (ko) 2023-12-04
EP3630967B8 (en) 2024-07-17
IL270949A (en) 2020-01-30
IL270950B1 (en) 2025-02-01
US12529044B2 (en) 2026-01-20
JP2020521460A (ja) 2020-07-27
US20230212543A1 (en) 2023-07-06
JP7195008B2 (ja) 2022-12-23
PL3630968T3 (pl) 2024-10-07
KR20200011955A (ko) 2020-02-04
WO2018215656A1 (en) 2018-11-29
ES2986910T3 (es) 2024-11-13
PL3630967T3 (pl) 2024-11-18
PT3630968T (pt) 2024-07-30
CA3063828A1 (en) 2018-11-29
FI3630967T3 (fi) 2024-08-12
IL270949B2 (en) 2025-06-01
PT3630967T (pt) 2024-08-21
JP2020522242A (ja) 2020-07-30
CN111183221A (zh) 2020-05-19
AU2018272984A1 (en) 2019-12-05
CN111183220A (zh) 2020-05-19
EP3630967B1 (en) 2024-06-12
JP7557896B2 (ja) 2024-09-30

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