KR102609790B1 - O-당단백질에 대한 프로테아제 및 결합 폴리펩티드 - Google Patents

O-당단백질에 대한 프로테아제 및 결합 폴리펩티드 Download PDF

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KR102609790B1
KR102609790B1 KR1020197036837A KR20197036837A KR102609790B1 KR 102609790 B1 KR102609790 B1 KR 102609790B1 KR 1020197036837 A KR1020197036837 A KR 1020197036837A KR 20197036837 A KR20197036837 A KR 20197036837A KR 102609790 B1 KR102609790 B1 KR 102609790B1
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KR20200010322A (ko
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프레드릭 레오
롤프 루드
스티븐 비요크
마린 메야르
프레드릭 올손
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게노비스 에이비
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Priority claimed from GBGB1708476.5A external-priority patent/GB201708476D0/en
Priority claimed from GBGB1708471.6A external-priority patent/GB201708471D0/en
Priority claimed from GBGB1806655.5A external-priority patent/GB201806655D0/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24057—O-Sialoglycoprotein endopeptidase (3.4.24.57), i.e. glycoprotease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/952—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from bacteria

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
KR1020197036837A 2017-05-26 2018-05-25 O-당단백질에 대한 프로테아제 및 결합 폴리펩티드 Active KR102609790B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB1708476.5 2017-05-26
GBGB1708476.5A GB201708476D0 (en) 2017-05-26 2017-05-26 Tools for glycan analysis
GBGB1708471.6A GB201708471D0 (en) 2017-05-26 2017-05-26 Polypeptide
GB1708471.6 2017-05-26
GB1806655.5 2018-04-24
GBGB1806655.5A GB201806655D0 (en) 2018-04-24 2018-04-24 Polypeptide
PCT/EP2018/063832 WO2018215656A1 (en) 2017-05-26 2018-05-25 Protease and binding polypeptide for o-glycoproteins

Publications (2)

Publication Number Publication Date
KR20200010322A KR20200010322A (ko) 2020-01-30
KR102609790B1 true KR102609790B1 (ko) 2023-12-04

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KR1020197036837A Active KR102609790B1 (ko) 2017-05-26 2018-05-25 O-당단백질에 대한 프로테아제 및 결합 폴리펩티드
KR1020197036845A Active KR102608876B1 (ko) 2017-05-26 2018-05-25 글리칸 분석을 위한 효소

Family Applications After (1)

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KR1020197036845A Active KR102608876B1 (ko) 2017-05-26 2018-05-25 글리칸 분석을 위한 효소

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US (3) US12448614B2 (enExample)
EP (2) EP3630968B8 (enExample)
JP (3) JP7195008B2 (enExample)
KR (2) KR102609790B1 (enExample)
CN (2) CN111183220B (enExample)
AU (2) AU2018272984B2 (enExample)
CA (2) CA3063828A1 (enExample)
DK (2) DK3630968T3 (enExample)
ES (2) ES2986557T3 (enExample)
FI (2) FI3630967T3 (enExample)
IL (2) IL270949B2 (enExample)
PL (2) PL3630967T3 (enExample)
PT (2) PT3630968T (enExample)
WO (2) WO2018215657A1 (enExample)

Families Citing this family (5)

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Publication number Priority date Publication date Assignee Title
PT3630968T (pt) * 2017-05-26 2024-07-30 Genovis Ab Enzimas para análise de glicanos
BR112021026789A2 (pt) * 2019-07-03 2022-05-10 Palleon Pharmaceuticals Inc Sialidases humanas recombinantes, proteínas de fusão de sialidase e métodos de uso das mesmas
CN112795583A (zh) * 2020-11-16 2021-05-14 上海大学 重组唾液酸外切酶的制备方法、表达基因、重组表达载体及构建方法
AU2022413663A1 (en) * 2021-12-15 2024-06-13 Danisco Us Inc. Compositions and methods involving proteases specific for mannose-modified proteins
WO2024118481A1 (en) * 2022-11-28 2024-06-06 Amgen Inc. Method of processing etanercept

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Publication number Priority date Publication date Assignee Title
US6720165B2 (en) 2001-06-14 2004-04-13 Zyomix, Inc. Methods for making antibody fragments and compositions resulting therefrom
US7807174B2 (en) * 2002-11-22 2010-10-05 Nexbio, Inc. Class of therapeutic protein based molecules
GB0624874D0 (en) 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
EP2281036B1 (en) 2008-04-18 2013-02-27 New England Biolabs, Inc. Endoglyosidases that cleave o-linked glycans
EP2166085A1 (en) 2008-07-16 2010-03-24 Suomen Punainen Risti Veripalvelu Divalent modified cells
US20100255487A1 (en) * 2009-03-27 2010-10-07 Life Technologies Corporation Methods and apparatus for single molecule sequencing using energy transfer detection
GB201115841D0 (en) 2011-09-13 2011-10-26 Genovis Ab Protein and method
GB201316744D0 (en) 2013-09-20 2013-11-06 Genovis Ab Method
WO2016003795A1 (en) 2014-07-02 2016-01-07 New England Biolabs, Inc. Universal n-glycan binding reagent
WO2017052433A1 (en) 2015-09-24 2017-03-30 Saab Ab A modular fluid actuator system
WO2017134274A1 (en) 2016-02-04 2017-08-10 Ulrich Von Pawel-Rammingen New streptococcal proteases
PT3630968T (pt) * 2017-05-26 2024-07-30 Genovis Ab Enzimas para análise de glicanos

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF VISUALIZED EXPERIMENTS, no. 58, p1-5(2011-12-26)*
NCBI Reference Sequence WP_012420160.1, ‘hypothetical protein [Akkermansia muciniphila]’, 2013.07.12.*

Also Published As

Publication number Publication date
PT3630967T (pt) 2024-08-21
AU2018272400A1 (en) 2019-12-05
ES2986910T3 (es) 2024-11-13
US11584922B2 (en) 2023-02-21
CN111183220A (zh) 2020-05-19
DK3630968T3 (da) 2024-07-29
KR102608876B1 (ko) 2023-11-30
US20200087643A1 (en) 2020-03-19
IL270950B1 (en) 2025-02-01
FI3630968T3 (fi) 2024-07-24
AU2018272984B2 (en) 2024-05-23
CN111183221B (zh) 2024-04-09
CN111183221A (zh) 2020-05-19
KR20200011955A (ko) 2020-02-04
EP3630967A1 (en) 2020-04-08
IL270949B1 (en) 2025-02-01
CA3063815A1 (en) 2018-11-29
EP3630967B8 (en) 2024-07-17
AU2018272400B2 (en) 2024-06-13
IL270950A (en) 2020-01-30
EP3630967B1 (en) 2024-06-12
PT3630968T (pt) 2024-07-30
IL270949A (en) 2020-01-30
JP2020521460A (ja) 2020-07-27
IL270949B2 (en) 2025-06-01
EP3630968A1 (en) 2020-04-08
IL270950B2 (en) 2025-06-01
WO2018215656A9 (en) 2019-03-14
WO2018215657A9 (en) 2019-03-14
PL3630968T3 (pl) 2024-10-07
JP7195008B2 (ja) 2022-12-23
US12448614B2 (en) 2025-10-21
US20200172889A1 (en) 2020-06-04
JP7557896B2 (ja) 2024-09-30
WO2018215656A1 (en) 2018-11-29
US20230212543A1 (en) 2023-07-06
CA3063828A1 (en) 2018-11-29
KR20200010322A (ko) 2020-01-30
CN111183220B (zh) 2024-03-22
JP2023103233A (ja) 2023-07-26
ES2986557T3 (es) 2024-11-11
PL3630967T3 (pl) 2024-11-18
JP2020522242A (ja) 2020-07-30
DK3630967T3 (da) 2024-08-19
WO2018215657A1 (en) 2018-11-29
AU2018272984A1 (en) 2019-12-05
EP3630968B8 (en) 2024-07-03
EP3630968B1 (en) 2024-05-29
FI3630967T3 (fi) 2024-08-12

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