CN111135132A - Composition for regulating skin heat dissipation and cosmetic - Google Patents
Composition for regulating skin heat dissipation and cosmetic Download PDFInfo
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- CN111135132A CN111135132A CN202010067855.1A CN202010067855A CN111135132A CN 111135132 A CN111135132 A CN 111135132A CN 202010067855 A CN202010067855 A CN 202010067855A CN 111135132 A CN111135132 A CN 111135132A
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- extract
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- heat dissipation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Dermatology (AREA)
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- Alternative & Traditional Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Organic Chemistry (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a composition for regulating skin heat dissipation, which comprises a reed extract and a dogwood extract. The composition for regulating the skin heat dissipation can regulate the heat dissipation capacity of the skin, and can slow down the rise amplitude of the skin temperature when the outside is at high temperature; and when the outside air temperature is lower, the speed of reducing the skin temperature can be slowed down. The invention also discloses a cosmetic and a skin external medicine containing the composition for regulating the skin heat dissipation.
Description
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to a composition for regulating skin heat dissipation and a cosmetic.
Background
When the skin is exposed to high temperature, the infrared dose to the skin is increased, which increases the expression of MMP-1, MMP-3, etc., thereby decreasing the synthesis of collagen and elastin in the skin, resulting in decreased elasticity of the skin and wrinkles.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide a composition for regulating skin heat dissipation and a cosmetic.
In order to achieve the purpose, the invention adopts the technical scheme that: a composition for regulating skin heat dissipation comprises Phragmites communis extract and Corni fructus extract.
The reed extract and the dogwood extract contain polysaccharide components, the gel structure of the reed extract and the dogwood extract is easy to change under the influence of external temperature, and when the reed extract and the dogwood extract absorb heat emitted by skin, the gel is changed into solution so as to absorb the heat emitted by the skin; and when the temperature is reduced, the gel can be recovered, so that the heat dissipation of the skin is reduced. The inventor finds that the heat dissipation capacity of the skin can be adjusted by matching the two components, and the rising amplitude of the skin temperature can be slowed down when the outside is high in temperature; and when the outside air temperature is lower, the speed of reducing the skin temperature can be slowed down.
Preferably, the weight ratio of the reed extract to the dogwood extract is as follows: reed extract: the ratio of the dogwood extract to the dogwood extract is 1-4: 1-4. When the reed extract and the dogwood extract are mixed according to the proportion, the cooling or heating speed of the skin can be effectively adjusted. More preferably, the weight ratio of the reed extract to the dogwood extract is: reed extract: the ratio of the dogwood extract to the dogwood extract is 2-3: 2-3. Most preferably, the weight ratio of the reed extract to the dogwood extract is: reed extract: the dogwood extract is 1: 1.
Preferably, the composition further comprises ginger root extract. The addition of the ginger root extract can be matched with the reed extract and the dogwood extract, and the outer wall of the skin is cooled or the cooling speed is reduced through heat dissipation of the surface of the skin.
Preferably, the ratio of the weight of the ginger root extract to the sum of the weight of the reed extract and the weight of the dogwood extract is as follows: ginger root extract: the sum of the reed extract and the dogwood extract is 1: 4-6. When the ginger root extract, the reed extract and the dogwood extract are mixed according to the proportion, the skin cooling speed is low.
The invention also aims to provide a cosmetic which contains the composition for regulating the heat dissipation of the skin.
Preferably, the composition for regulating the skin heat dissipation accounts for 0.1-50% of the weight of the cosmetic.
Preferably, the composition for regulating the skin heat dissipation accounts for 0.5-5 wt% of the cosmetic.
Preferably, the cosmetic is a water, an emulsion or an ointment.
The invention also aims to provide a skin external medicament, which comprises the composition for regulating the skin heat dissipation.
The invention has the beneficial effects that: the invention provides a composition for regulating skin heat dissipation. The composition for regulating the skin heat dissipation can regulate the heat dissipation capacity of the skin, and can slow down the rise amplitude of the skin temperature when the outside is at high temperature; and when the outside air temperature is lower, the speed of reducing the skin temperature can be slowed down. The invention also provides a cosmetic and a skin external medicine containing the composition for regulating the skin heat dissipation.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
Example 1
The preparation method of the reed extract and the dogwood extract comprises the following steps: cutting the whole reed and dogwood respectively, placing the cut whole reed and dogwood into pure water for ultrasonic extraction to obtain reed and dogwood extracting solutions, decoloring the extracting solutions through D101 macroporous resin, desalting the extracting solutions through Sephadex G-15 column chromatography, distilling the obtained extracting solutions to obtain extractum, treating the extractum with 95% ethanol in a ratio of 1:5, centrifuging the extractum, taking insoluble substances on the lower layer, preparing the lower layer into 10% aqueous solution with purified water, and filtering the aqueous solution with 200 meshes to obtain the reed extract and the dogwood extract.
The viscosities of the Phragmites communis extract and the dogwood extract were measured at different ratios at different temperatures using a Brookfield DV2T type viscometer (spindle # 1, 12 rpm), and the results are shown in Table 1.
TABLE 1
The more obvious the change of the viscosity of the composition along with the temperature is, the more easy the heat energy is converted into the change of the molecular weight in the gel of the composition, the heat energy is stored in the gel, and the composition is applied to the skin, so that the change amplitude of the skin along with the temperature change can be reduced, and the damage of the skin to the difference of the temperature change of the environment can be reduced.
As can be seen from table 1, when the reed extract and the dogwood extract are compounded, the viscosity fluctuates with temperature more obviously than that of the single reed extract or the dogwood extract, wherein when the mass ratio of the reed extract to the dogwood extract is 1:1, the difference of the viscosity with temperature fluctuation is the largest.
Example 2
The emulsion was prepared according to the formulation in table 2, the preparation method being: adding butanediol, carbomer, p-hydroxyacetophenone, and hexanediol under stirring, heating to 80 deg.C, holding for 20 min, homogenizing at high speed for two minutes, cooling to 45 deg.C, adding arginine, rhizoma Zingiberis recens extract, rhizoma Phragmitis extract, and Corni fructus extract, stirring, and filtering with 200 mesh double-layer filter cloth.
TABLE 2
| Component (%) | Test group 1 | Test group 2 | Test group 3 | Test group 4 | Control group 1 | Control group 2 |
| Water (W) | Balance of | Balance of | Balance of | Balance of | Balance of | Balance of |
| Butanediol | 8 | 8 | 8 | 8 | 8 | 8 |
| Carbomer | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| Arginine | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| P-hydroxyacetophenone | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 |
| Hexanediol | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| Ginger root extract | 1 | 1 | 1 | 0 | 1 | 1 |
| Phragmites communis extract | 2.5 | 2 | 3 | 2.5 | 5 | 0 |
| Extract of cornus officinalis | 2.5 | 3 | 2 | 2.5 | 0 | 5 |
Testing an instrument: the skin temperature test probe is used for testing by adopting an MPA 580 skin tester of CK company and matching with an ST500 skin temperature test probe.
Test samples: the health condition of 30 tested volunteers and 5 tested volunteers was normal skin.
The test method comprises the following steps: about 60-70 cm to the outer side of the forearm of the hand of the volunteer2The area was coated with 2g of the emulsions of test groups 1 to 4 and control groups 1 and 2, respectively, and the skin temperature was measured after increasing the ambient temperature from 10 ℃ to 15 ℃, 25 ℃, 30 ℃ and 35 ℃ in sequence, and maintaining each temperature for 30 min.
1. Skin heat dissipation experiment at low temperature
Calculating average temperature value of skin tested in environment of 10 deg.C, 15 deg.C and 25 deg.C, and calculating temperature difference T between 10 deg.C and 25 deg.C1。
2. Skin heat dissipation experiment at high temperature
Calculating average temperature value of skin tested in environment of 25 deg.C, 30 deg.C and 35 deg.C, and calculating temperature difference T between 25 deg.C and 35 deg.C2。
3. Skin elasticity test: the skin elasticity is tested after the emulsions of test groups 1-4 and control groups 1 and 2 are used for four weeks, wherein the skin elasticity is expressed as: the skin elasticity change rate (%) was calculated as skin elasticity change rate (skin elasticity after 4 weeks use-skin elasticity before use)/skin elasticity before use 100%.
The test results are shown in Table 3.
TABLE 3
As can be seen from the results in table 3, when compared with the case of adding the reed extract or the dogwood extract alone, the reed extract and the dogwood extract can better control the body temperature and have a certain effect of improving the skin elasticity, and especially when the weight ratio of the reed extract to the dogwood extract is 1:1, the body temperature control effect is the best, and the skin elasticity is greatly improved. As can be seen from the comparison between the test group 1 and the test group 4, the addition of the ginger root extract has a certain effect of alleviating the skin heat dissipation.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (10)
1. A composition for regulating skin heat dissipation is characterized by comprising a reed extract and a dogwood extract.
2. The composition for regulating skin heat dissipation of claim 1, wherein the weight ratio of the reed extract to the dogwood extract is: reed extract: the ratio of the dogwood extract to the dogwood extract is 1-4: 1-4.
3. The composition for regulating skin heat dissipation of claim 1, wherein the weight ratio of the reed extract to the dogwood extract is: reed extract: the ratio of the dogwood extract to the dogwood extract is 2-3: 2-3.
4. The composition for regulating skin heat dissipation of claim 1, wherein the weight ratio of the reed extract to the dogwood extract is: reed extract: the dogwood extract is 1: 1.
5. The composition for regulating skin heat dissipation of claim 1, wherein the composition further comprises ginger root extract.
6. The composition for regulating skin heat dissipation of claim 5, wherein the ratio of the weight of the ginger root extract to the sum of the weight of the reed extract and the dogwood extract is: ginger root extract: the sum of the reed extract and the dogwood extract is 1: 4-6.
7. A cosmetic comprising the composition for regulating skin heat dissipation according to any one of claims 1 to 6.
8. The cosmetic of claim 7, wherein the composition for regulating skin heat dissipation comprises 0.1 to 50% by weight of the cosmetic; preferably, the composition for regulating the skin heat dissipation accounts for 0.5-5 wt% of the cosmetic.
9. The cosmetic of claim 7, wherein the cosmetic is a water, an emulsion or an ointment.
10. A skin external medicine comprising the composition for regulating skin heat dissipation according to any one of claims 1 to 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010067855.1A CN111135132A (en) | 2020-01-19 | 2020-01-19 | Composition for regulating skin heat dissipation and cosmetic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010067855.1A CN111135132A (en) | 2020-01-19 | 2020-01-19 | Composition for regulating skin heat dissipation and cosmetic |
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| Publication Number | Publication Date |
|---|---|
| CN111135132A true CN111135132A (en) | 2020-05-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010067855.1A Pending CN111135132A (en) | 2020-01-19 | 2020-01-19 | Composition for regulating skin heat dissipation and cosmetic |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130114502A (en) * | 2012-04-09 | 2013-10-17 | 주식회사 엔에스텍 | Cosmetic compositions comprising the extract of cornus officinalis as an active ingredient |
| CN104337738A (en) * | 2014-11-14 | 2015-02-11 | 刘芳 | Composition of dogwood extracts for skin wrinkle resisting and preparation method thereof |
| CN106880561A (en) * | 2015-12-11 | 2017-06-23 | 高丽雅娜化妆品股份有限公司 | The cosmetic composition containing black bamboo extract for adjusting skin temperature |
| KR20170101342A (en) * | 2016-02-26 | 2017-09-06 | 정의수 | Natural plant mixed extracts that regulate heat of the skin and a cosmetic composition for skin heat anti-aging that containing the same |
| KR20170137546A (en) * | 2016-06-03 | 2017-12-13 | 주식회사 엘지생활건강 | Composition for improving skin condition comprising herb extracts mixture |
| CN107890561A (en) * | 2018-01-04 | 2018-04-10 | 邹大鹏 | A kind of Linimentum of Chinese herbal medicine for being used to treat nettle rash |
| CN109793693A (en) * | 2019-03-12 | 2019-05-24 | 广州科恩生物技术有限公司 | A kind of moist toner and preparation method thereof of staying up late of plant |
-
2020
- 2020-01-19 CN CN202010067855.1A patent/CN111135132A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130114502A (en) * | 2012-04-09 | 2013-10-17 | 주식회사 엔에스텍 | Cosmetic compositions comprising the extract of cornus officinalis as an active ingredient |
| CN104337738A (en) * | 2014-11-14 | 2015-02-11 | 刘芳 | Composition of dogwood extracts for skin wrinkle resisting and preparation method thereof |
| CN106880561A (en) * | 2015-12-11 | 2017-06-23 | 高丽雅娜化妆品股份有限公司 | The cosmetic composition containing black bamboo extract for adjusting skin temperature |
| KR20170101342A (en) * | 2016-02-26 | 2017-09-06 | 정의수 | Natural plant mixed extracts that regulate heat of the skin and a cosmetic composition for skin heat anti-aging that containing the same |
| KR20170137546A (en) * | 2016-06-03 | 2017-12-13 | 주식회사 엘지생활건강 | Composition for improving skin condition comprising herb extracts mixture |
| CN107890561A (en) * | 2018-01-04 | 2018-04-10 | 邹大鹏 | A kind of Linimentum of Chinese herbal medicine for being used to treat nettle rash |
| CN109793693A (en) * | 2019-03-12 | 2019-05-24 | 广州科恩生物技术有限公司 | A kind of moist toner and preparation method thereof of staying up late of plant |
Non-Patent Citations (6)
| Title |
|---|
| FERNANDO, PDSM 等: ""xtract of Cornus officinalis Protects Keratinocytes from Particulate Matter-induced Oxidative Stress"", 《INTERNATIONAL JOURNAL OF MEDICAL SCIENCES》 * |
| 孙海峰: "《中药化妆品开发与应用》", 30 June 2017, 人民卫生出版社 * |
| 张学伟: "《中国居民膳食指南》", 31 July 2015, 中医古籍出版社 * |
| 李文海 等: ""皮肤老化的新形势-热老化"", 《临床皮肤科杂志》 * |
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| 陈高敏 等: ""中药植物多糖抗皮肤光老化的研究进展"", 《南京中医药大学学报》 * |
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Application publication date: 20200512 |