CN111110850A - 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法 - Google Patents

用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法 Download PDF

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Publication number
CN111110850A
CN111110850A CN201910892185.4A CN201910892185A CN111110850A CN 111110850 A CN111110850 A CN 111110850A CN 201910892185 A CN201910892185 A CN 201910892185A CN 111110850 A CN111110850 A CN 111110850A
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kinase
pharmaceutical composition
lung
another embodiment
seq
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Chinese (zh)
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辛西娅.兰德
科琳.布罗菲
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Moerae Matrix Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN201910892185.4A 2011-04-12 2012-04-12 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法 Pending CN111110850A (zh)

Applications Claiming Priority (3)

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US201161474370P 2011-04-12 2011-04-12
US61/474370 2011-04-12
CN201280027012.2A CN104302310A (zh) 2011-04-12 2012-04-12 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病、病状或病程的组合物和方法

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CN201910892185.4A Pending CN111110850A (zh) 2011-04-12 2012-04-12 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法
CN201280027012.2A Pending CN104302310A (zh) 2011-04-12 2012-04-12 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病、病状或病程的组合物和方法
CN201711403446.9A Pending CN108014340A (zh) 2011-04-12 2012-04-12 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法

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CN201280027012.2A Pending CN104302310A (zh) 2011-04-12 2012-04-12 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病、病状或病程的组合物和方法
CN201711403446.9A Pending CN108014340A (zh) 2011-04-12 2012-04-12 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法

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JP (1) JP6031510B2 (cg-RX-API-DMAC7.html)
KR (1) KR101862291B1 (cg-RX-API-DMAC7.html)
CN (3) CN111110850A (cg-RX-API-DMAC7.html)
AU (1) AU2012242768B2 (cg-RX-API-DMAC7.html)
BR (1) BR112013026313A8 (cg-RX-API-DMAC7.html)
CA (2) CA2832910C (cg-RX-API-DMAC7.html)
DK (1) DK2696888T3 (cg-RX-API-DMAC7.html)
ES (1) ES2711670T3 (cg-RX-API-DMAC7.html)
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SG (2) SG194135A1 (cg-RX-API-DMAC7.html)
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US20120263680A1 (en) 2012-10-18
SG10201604560TA (en) 2016-07-28
CA2832910C (en) 2019-07-02
CN108014340A (zh) 2018-05-11
BR112013026313A2 (pt) 2016-12-27
DK2696888T3 (en) 2019-03-25
NZ616672A (en) 2016-04-29
WO2012142320A2 (en) 2012-10-18
SG194135A1 (en) 2013-11-29
CA3042808A1 (en) 2012-10-18
KR101862291B1 (ko) 2018-05-29
EP2696888A2 (en) 2014-02-19
JP2014533235A (ja) 2014-12-11
ES2711670T3 (es) 2019-05-06
EP2696888B1 (en) 2018-12-05
MX2013011771A (es) 2014-07-30
US20190022169A1 (en) 2019-01-24
HK1255005A1 (zh) 2019-08-02
RU2013150249A (ru) 2015-05-20
CA2832910A1 (en) 2012-10-18
AU2012242768A1 (en) 2013-10-24
EP2696888A4 (en) 2016-04-20
RU2620066C2 (ru) 2017-05-22
WO2012142320A8 (en) 2014-02-20
KR20140063517A (ko) 2014-05-27
WO2012142320A3 (en) 2015-06-11
MX359516B (es) 2018-10-01
BR112013026313A8 (pt) 2018-01-30
US9642888B2 (en) 2017-05-09
AU2012242768B2 (en) 2017-10-12
JP6031510B2 (ja) 2016-11-24
CN104302310A (zh) 2015-01-21

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