CN111051332B - 免疫调节剂 - Google Patents

免疫调节剂 Download PDF

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Publication number
CN111051332B
CN111051332B CN201880055279.XA CN201880055279A CN111051332B CN 111051332 B CN111051332 B CN 111051332B CN 201880055279 A CN201880055279 A CN 201880055279A CN 111051332 B CN111051332 B CN 111051332B
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dmf
resin
fmoc
frit
solution
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Chinese (zh)
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CN111051332A (zh
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M·M·米勒
M·P·艾伦
李玲
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201880055279.XA 2017-10-03 2018-10-02 免疫调节剂 Active CN111051332B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762567323P 2017-10-03 2017-10-03
US62/567,323 2017-10-03
PCT/US2018/053871 WO2019070643A1 (en) 2017-10-03 2018-10-02 IMMUNOMODULATORS

Publications (2)

Publication Number Publication Date
CN111051332A CN111051332A (zh) 2020-04-21
CN111051332B true CN111051332B (zh) 2024-09-06

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ID=63998773

Family Applications (1)

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CN201880055279.XA Active CN111051332B (zh) 2017-10-03 2018-10-02 免疫调节剂

Country Status (6)

Country Link
US (1) US11492375B2 (https=)
EP (1) EP3692053A1 (https=)
JP (1) JP7257393B2 (https=)
KR (1) KR20200058506A (https=)
CN (1) CN111051332B (https=)
WO (1) WO2019070643A1 (https=)

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CN111961117B (zh) * 2020-08-19 2022-03-11 中山大学 一种环肽化合物及其应用
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CN117858719A (zh) 2021-03-29 2024-04-09 朱诺治疗学股份有限公司 使用检查点抑制剂疗法和car t细胞疗法的组合进行给药和治疗的方法
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KR20240135661A (ko) 2022-01-26 2024-09-11 브리스톨-마이어스 스큅 컴퍼니 간세포성 암종에 대한 조합 요법
JP7851417B2 (ja) 2022-04-08 2026-04-24 ブリストル－マイヤーズ スクイブ カンパニー 三次リンパ組織様構造の機械学習識別、分類、及び定量化
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Also Published As

Publication number Publication date
CN111051332A (zh) 2020-04-21
WO2019070643A1 (en) 2019-04-11
KR20200058506A (ko) 2020-05-27
US11492375B2 (en) 2022-11-08
JP2020536091A (ja) 2020-12-10
US20200291069A1 (en) 2020-09-17
JP7257393B2 (ja) 2023-04-13
EP3692053A1 (en) 2020-08-12

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