CN110945012A - 新型肽和用于治疗眼病的包含所述新型肽作为活性药物成分的药物组合物 - Google Patents

新型肽和用于治疗眼病的包含所述新型肽作为活性药物成分的药物组合物 Download PDF

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Publication number
CN110945012A
CN110945012A CN201880047540.1A CN201880047540A CN110945012A CN 110945012 A CN110945012 A CN 110945012A CN 201880047540 A CN201880047540 A CN 201880047540A CN 110945012 A CN110945012 A CN 110945012A
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yde
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Chinese (zh)
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T.白
T-S.金
D-S.林
D.邱
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Yuyu Pharma Inc
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Yuyu Pharma Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201880047540.1A 2017-05-17 2018-05-17 新型肽和用于治疗眼病的包含所述新型肽作为活性药物成分的药物组合物 Pending CN110945012A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20170061250 2017-05-17
KR10-2017-0061250 2017-05-17
PCT/KR2018/005673 WO2018225961A1 (ko) 2017-05-17 2018-05-17 신규한 펩타이드 및 이를 유효성분으로 포함하는 안구질환 치료용 약학 조성물

Publications (1)

Publication Number Publication Date
CN110945012A true CN110945012A (zh) 2020-03-31

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Family Applications (1)

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CN201880047540.1A Pending CN110945012A (zh) 2017-05-17 2018-05-17 新型肽和用于治疗眼病的包含所述新型肽作为活性药物成分的药物组合物

Country Status (13)

Country Link
US (1) US12037415B2 (https=)
EP (1) EP3643723B1 (https=)
JP (2) JP7680824B2 (https=)
KR (2) KR102287226B1 (https=)
CN (1) CN110945012A (https=)
AU (1) AU2018281617B2 (https=)
BR (1) BR112019024040A2 (https=)
CA (1) CA3063842A1 (https=)
ES (1) ES2982308T3 (https=)
MX (1) MX2019013799A (https=)
RU (1) RU2766160C2 (https=)
SG (1) SG11201912110YA (https=)
WO (1) WO2018225961A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI889483B (zh) * 2023-08-10 2025-07-01 南韓商凱爾格恩有限公司 具有改善乾眼症活性的新型胜肽及包括其之藥物組合物

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102287226B1 (ko) 2017-05-17 2021-08-11 주식회사 유유제약 신규한 펩타이드 및 이를 유효성분으로 포함하는 안구질환 치료용 약학 조성물
US11613558B2 (en) 2018-11-14 2023-03-28 Yuyu Pharma, Inc. Peptides and pharmaceutical compositions for treating eye diseases
TWI865470B (zh) * 2018-11-14 2024-12-11 南韓商柳柳製藥股份有限公司 治療眼睛疾病之肽及醫藥組合物
JP7576048B2 (ja) * 2019-05-21 2024-10-30 アイバイオ コリア 新規なペプチド化合物またはその薬学的に許容される塩
KR20210104460A (ko) * 2020-02-17 2021-08-25 주식회사 아이바이오코리아 고체상 합성법을 이용한 펩타이드의 제조 방법
EP4114430A4 (en) * 2020-03-05 2025-05-14 YUYU Pharma, Inc. TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS
KR102593936B1 (ko) * 2021-12-13 2023-10-27 주식회사 아이바이오코리아 신규한 펩타이드를 포함하는 황반변성의 치료용 조성물
AU2022412618B2 (en) * 2021-12-13 2026-02-19 Eyebiokorea, Inc. Composition for treating macular degeneration comprising novel peptide
KR102587729B1 (ko) * 2023-02-27 2023-10-12 주식회사 아이바이오코리아 펩타이드를 포함하는 당뇨망막병증의 치료용 조성물

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
CN102177173A (zh) * 2008-09-30 2011-09-07 新田明胶株式会社 胶原肽,二肽及疾病抑制剂
WO2017018613A1 (ko) * 2015-07-30 2017-02-02 인제대학교 산학협력단 건성안 예방 또는 치료용 약학조성물

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007117444A2 (en) * 2006-03-31 2007-10-18 Yinghe Hu Protein detection by aptamers
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
US20090131303A1 (en) * 2007-11-16 2009-05-21 Bor-Shyue Hong Methods and compositions for treating dry eye
CA2836946C (en) * 2011-05-27 2017-08-01 Allergan, Inc. A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof
MX2014006399A (es) * 2011-11-30 2015-04-10 Xigen Inflammation Ltd Uso de inhibidores de peptidos con celulas permeables de la via para transduccion de señal de jnk para el tratamiento de la queratoconjuntivitis seca.
KR101438744B1 (ko) * 2012-08-02 2014-09-15 전남대학교산학협력단 아디포넥틴을 유효성분으로 포함하는 안구건조증 또는 염증성 안구표면 질환의 예방 또는 치료용 조성물
KR101555296B1 (ko) 2013-12-10 2015-09-23 인제대학교 산학협력단 연골세포 유래 세포외 기질을 유효성분으로 함유하는 건성안 예방 또는 치료용 약학조성물
KR101948156B1 (ko) 2013-12-10 2019-02-14 인제대학교 산학협력단 알칼리 화상을 이용한 각막 혼탁증 동물모델 및 각막 혼탁증 예방 또는 치료용 약학조성물
KR101721059B1 (ko) 2014-12-26 2017-03-30 주식회사 아이바이오코리아 안구 표면 질환 예방 또는 치료용 약학조성물
TWI675851B (zh) 2015-12-14 2019-11-01 台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 短合成胜肽及其用途
CN109310731B (zh) * 2016-04-08 2022-03-29 韩国视角生物株式会社 软骨细胞的细胞外基质来源的肽
KR101798183B1 (ko) * 2016-04-08 2017-11-15 주식회사 아이바이오코리아 건성안 예방 또는 치료용 약학조성물
KR101795653B1 (ko) 2016-05-19 2017-11-09 인제대학교 산학협력단 콜라겐 타입 ii 펩타이드-아플리버셉트의 키메라 단백질을 유효성분으로 함유하는 혈관신생 억제용 조성물
KR20180074928A (ko) 2016-12-26 2018-07-04 주식회사 아이바이오코리아 건성안 예방 또는 치료용 동물 의약품 조성물
KR102287226B1 (ko) 2017-05-17 2021-08-11 주식회사 유유제약 신규한 펩타이드 및 이를 유효성분으로 포함하는 안구질환 치료용 약학 조성물
TWI865470B (zh) * 2018-11-14 2024-12-11 南韓商柳柳製藥股份有限公司 治療眼睛疾病之肽及醫藥組合物
US11613558B2 (en) 2018-11-14 2023-03-28 Yuyu Pharma, Inc. Peptides and pharmaceutical compositions for treating eye diseases
EP4114430A4 (en) * 2020-03-05 2025-05-14 YUYU Pharma, Inc. TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
CN102177173A (zh) * 2008-09-30 2011-09-07 新田明胶株式会社 胶原肽,二肽及疾病抑制剂
WO2017018613A1 (ko) * 2015-07-30 2017-02-02 인제대학교 산학협력단 건성안 예방 또는 치료용 약학조성물

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HYESOOK LEE 等: ""Anti-infammatory efect of hydroxyproline-GQDGLAGPK in desiccation stress-induced experimental dry eye mouse"" *
姚小琪: ""玻璃酸钠滴眼液与双氯芬酸钠滴眼液治疗干眼症临床观察"" *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI889483B (zh) * 2023-08-10 2025-07-01 南韓商凱爾格恩有限公司 具有改善乾眼症活性的新型胜肽及包括其之藥物組合物

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AU2018281617B2 (en) 2022-06-30
SG11201912110YA (en) 2020-01-30
EP3643723B1 (en) 2024-05-15
RU2019141646A3 (https=) 2021-07-28
ES2982308T3 (es) 2024-10-15
JP2023098936A (ja) 2023-07-11
RU2019141646A (ru) 2021-06-17
JP2020520372A (ja) 2020-07-09
US12037415B2 (en) 2024-07-16
BR112019024040A2 (pt) 2020-09-24
US20210024577A1 (en) 2021-01-28
RU2766160C2 (ru) 2022-02-08
EP3643723C0 (en) 2024-05-15
MX2019013799A (es) 2020-08-13
KR102498428B1 (ko) 2023-02-20
EP3643723A1 (en) 2020-04-29
CA3063842A1 (en) 2019-12-09
AU2018281617A1 (en) 2019-12-05
KR20210097670A (ko) 2021-08-09
EP3643723A4 (en) 2021-03-31
WO2018225961A1 (ko) 2018-12-13
KR102287226B1 (ko) 2021-08-11
KR20180126406A (ko) 2018-11-27
JP7775250B2 (ja) 2025-11-25
JP7680824B2 (ja) 2025-05-21

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