JP7680824B2 - 新規ペプチド及びその新規ペプチドを活性成分として含む眼疾患の治療のための医薬組成物 - Google Patents

新規ペプチド及びその新規ペプチドを活性成分として含む眼疾患の治療のための医薬組成物 Download PDF

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JP7680824B2
JP7680824B2 JP2019563617A JP2019563617A JP7680824B2 JP 7680824 B2 JP7680824 B2 JP 7680824B2 JP 2019563617 A JP2019563617 A JP 2019563617A JP 2019563617 A JP2019563617 A JP 2019563617A JP 7680824 B2 JP7680824 B2 JP 7680824B2
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JP2020520372A (ja
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ベク,テゴン
キム,テク-ス
リム,デ-ソン
グ,ドゥク-ヨン
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ユーユー ファーマ,インコーポレーテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02Linear peptides containing at least one abnormal peptide link
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2019563617A 2017-05-17 2018-05-17 新規ペプチド及びその新規ペプチドを活性成分として含む眼疾患の治療のための医薬組成物 Active JP7680824B2 (ja)

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JP2023061251A JP7775250B2 (ja) 2017-05-17 2023-04-05 新規ペプチド及びその新規ペプチドを活性成分として含む眼疾患の治療のための医薬組成物

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KR20170061250 2017-05-17
KR10-2017-0061250 2017-05-17
PCT/KR2018/005673 WO2018225961A1 (ko) 2017-05-17 2018-05-17 신규한 펩타이드 및 이를 유효성분으로 포함하는 안구질환 치료용 약학 조성물

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JP2020520372A5 JP2020520372A5 (https=) 2021-07-26
JP7680824B2 true JP7680824B2 (ja) 2025-05-21

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JP2023061251A Active JP7775250B2 (ja) 2017-05-17 2023-04-05 新規ペプチド及びその新規ペプチドを活性成分として含む眼疾患の治療のための医薬組成物

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US (1) US12037415B2 (https=)
EP (1) EP3643723B1 (https=)
JP (2) JP7680824B2 (https=)
KR (2) KR102287226B1 (https=)
CN (1) CN110945012A (https=)
AU (1) AU2018281617B2 (https=)
BR (1) BR112019024040A2 (https=)
CA (1) CA3063842A1 (https=)
ES (1) ES2982308T3 (https=)
MX (1) MX2019013799A (https=)
RU (1) RU2766160C2 (https=)
SG (1) SG11201912110YA (https=)
WO (1) WO2018225961A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102287226B1 (ko) 2017-05-17 2021-08-11 주식회사 유유제약 신규한 펩타이드 및 이를 유효성분으로 포함하는 안구질환 치료용 약학 조성물
US11613558B2 (en) 2018-11-14 2023-03-28 Yuyu Pharma, Inc. Peptides and pharmaceutical compositions for treating eye diseases
TWI865470B (zh) * 2018-11-14 2024-12-11 南韓商柳柳製藥股份有限公司 治療眼睛疾病之肽及醫藥組合物
JP7576048B2 (ja) * 2019-05-21 2024-10-30 アイバイオ コリア 新規なペプチド化合物またはその薬学的に許容される塩
KR20210104460A (ko) * 2020-02-17 2021-08-25 주식회사 아이바이오코리아 고체상 합성법을 이용한 펩타이드의 제조 방법
EP4114430A4 (en) * 2020-03-05 2025-05-14 YUYU Pharma, Inc. TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS
KR102593936B1 (ko) * 2021-12-13 2023-10-27 주식회사 아이바이오코리아 신규한 펩타이드를 포함하는 황반변성의 치료용 조성물
AU2022412618B2 (en) * 2021-12-13 2026-02-19 Eyebiokorea, Inc. Composition for treating macular degeneration comprising novel peptide
KR102587729B1 (ko) * 2023-02-27 2023-10-12 주식회사 아이바이오코리아 펩타이드를 포함하는 당뇨망막병증의 치료용 조성물
KR102673860B1 (ko) * 2023-08-10 2024-06-12 (주)케어젠 안구 건조증의 개선 활성을 갖는 펩타이드 및 이의 용도

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101795653B1 (ko) 2016-05-19 2017-11-09 인제대학교 산학협력단 콜라겐 타입 ii 펩타이드-아플리버셉트의 키메라 단백질을 유효성분으로 함유하는 혈관신생 억제용 조성물
JP2019519597A (ja) 2016-04-08 2019-07-11 アイバイオ コリアEyebio Korea 軟骨細胞の細胞外基質由来ペプチド

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
WO2007117444A2 (en) * 2006-03-31 2007-10-18 Yinghe Hu Protein detection by aptamers
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
US20090131303A1 (en) * 2007-11-16 2009-05-21 Bor-Shyue Hong Methods and compositions for treating dry eye
JP4490498B2 (ja) 2008-09-30 2010-06-23 新田ゼラチン株式会社 疾病抑制剤
CA2836946C (en) * 2011-05-27 2017-08-01 Allergan, Inc. A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof
MX2014006399A (es) * 2011-11-30 2015-04-10 Xigen Inflammation Ltd Uso de inhibidores de peptidos con celulas permeables de la via para transduccion de señal de jnk para el tratamiento de la queratoconjuntivitis seca.
KR101438744B1 (ko) * 2012-08-02 2014-09-15 전남대학교산학협력단 아디포넥틴을 유효성분으로 포함하는 안구건조증 또는 염증성 안구표면 질환의 예방 또는 치료용 조성물
KR101555296B1 (ko) 2013-12-10 2015-09-23 인제대학교 산학협력단 연골세포 유래 세포외 기질을 유효성분으로 함유하는 건성안 예방 또는 치료용 약학조성물
KR101948156B1 (ko) 2013-12-10 2019-02-14 인제대학교 산학협력단 알칼리 화상을 이용한 각막 혼탁증 동물모델 및 각막 혼탁증 예방 또는 치료용 약학조성물
KR101721059B1 (ko) 2014-12-26 2017-03-30 주식회사 아이바이오코리아 안구 표면 질환 예방 또는 치료용 약학조성물
KR101690539B1 (ko) 2015-07-30 2016-12-29 주식회사 아이바이오코리아 건성안 예방 또는 치료용 약학조성물
TWI675851B (zh) 2015-12-14 2019-11-01 台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 短合成胜肽及其用途
KR101798183B1 (ko) * 2016-04-08 2017-11-15 주식회사 아이바이오코리아 건성안 예방 또는 치료용 약학조성물
KR20180074928A (ko) 2016-12-26 2018-07-04 주식회사 아이바이오코리아 건성안 예방 또는 치료용 동물 의약품 조성물
KR102287226B1 (ko) 2017-05-17 2021-08-11 주식회사 유유제약 신규한 펩타이드 및 이를 유효성분으로 포함하는 안구질환 치료용 약학 조성물
TWI865470B (zh) * 2018-11-14 2024-12-11 南韓商柳柳製藥股份有限公司 治療眼睛疾病之肽及醫藥組合物
US11613558B2 (en) 2018-11-14 2023-03-28 Yuyu Pharma, Inc. Peptides and pharmaceutical compositions for treating eye diseases
EP4114430A4 (en) * 2020-03-05 2025-05-14 YUYU Pharma, Inc. TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019519597A (ja) 2016-04-08 2019-07-11 アイバイオ コリアEyebio Korea 軟骨細胞の細胞外基質由来ペプチド
KR101795653B1 (ko) 2016-05-19 2017-11-09 인제대학교 산학협력단 콜라겐 타입 ii 펩타이드-아플리버셉트의 키메라 단백질을 유효성분으로 함유하는 혈관신생 억제용 조성물

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AU2018281617B2 (en) 2022-06-30
SG11201912110YA (en) 2020-01-30
EP3643723B1 (en) 2024-05-15
RU2019141646A3 (https=) 2021-07-28
ES2982308T3 (es) 2024-10-15
JP2023098936A (ja) 2023-07-11
RU2019141646A (ru) 2021-06-17
JP2020520372A (ja) 2020-07-09
CN110945012A (zh) 2020-03-31
US12037415B2 (en) 2024-07-16
BR112019024040A2 (pt) 2020-09-24
US20210024577A1 (en) 2021-01-28
RU2766160C2 (ru) 2022-02-08
EP3643723C0 (en) 2024-05-15
MX2019013799A (es) 2020-08-13
KR102498428B1 (ko) 2023-02-20
EP3643723A1 (en) 2020-04-29
CA3063842A1 (en) 2019-12-09
AU2018281617A1 (en) 2019-12-05
KR20210097670A (ko) 2021-08-09
EP3643723A4 (en) 2021-03-31
WO2018225961A1 (ko) 2018-12-13
KR102287226B1 (ko) 2021-08-11
KR20180126406A (ko) 2018-11-27
JP7775250B2 (ja) 2025-11-25

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