CN110917383A - Deodorizing dressing with high comfort and air permeability and preparation method thereof - Google Patents

Abstract

The invention relates to the field of medical dressings, in particular to a deodorizing dressing with high comfort and air permeability and a preparation method thereof. The main component of the traditional vaseline dressing is vaseline, the melting temperature of the vaseline ranges from 45 ℃ to 60 ℃, if the vaseline is stored or used in a low-temperature environment, the vaseline is massive, hard in texture and low in fitting property, comfort is low after the vaseline is contacted with a wound surface, the vaseline dressing is not suitable for filling of certain cavity wounds, discomfort and pain are caused to patients, the vaseline dressing needs to be heated in advance and then used, healing time of chronic wounds or infected wounds is relatively long, and psychological burden and distress are brought to the wounds due to peculiar smell often emitted by the wounds when the traditional vaseline dressing is used. Aiming at the problems, the deodorant dressing with high comfort and air permeability provided by the invention has good air permeability, lower softening point, no need of preheating during use, good comfort for patients at lower temperature, and good application prospect, and can permanently cover and absorb the unpleasant odor generated in the wound healing process.

Description

Deodorizing dressing with high comfort and air permeability and preparation method thereof

Technical Field

The invention relates to the field of medical dressings, in particular to a deodorizing dressing with high comfort and air permeability and a preparation method thereof.

Background

In clinic, some infectious or chronic wounds can seep, and medical workers usually select vaseline oil gauze dressing to perform seepage drainage and cover nursing, such as burn wounds, anorectal operation wounds, pressure sores and donor skin area wounds. This kind of dressing still has the performance that prevents gauze and wound adhesion, causes secondary damage to the wound when avoiding changing dressings, is favorable to the growth of fresh granulation tissue. However, the healing time of such chronic wounds or infected wounds is usually relatively long, which not only causes physical pain to the patient, but also causes psychological burden and distress to the patient due to the often-emitted bad smell of the wounds, which has not been solved by using the conventional vaseline dressing. Meanwhile, the main component of the traditional vaseline dressing is vaseline, because the melting temperature range of the vaseline is 45-60 ℃, if the vaseline is stored or used in a cold environment, the vaseline is blocky, hard in texture and low in fitting property, is low in comfort after contacting with a wound surface, is not suitable for filling of some cavity wounds to cause discomfort and pain of a patient, and needs to be heated in advance for use, for example, Chinese patent CN 104623718A discloses chitosan vaseline gauze, which is prepared by the following steps: dissolving the chitosan mixture in weak acid solution to prepare chitosan mixed solution; then soaking the medical gauze in the chitosan mixed solution to prepare chitosan gauze, and soaking the chitosan gauze in the melted mixed solution of vaseline and paraffin oil to obtain the chitosan vaseline gauze with the concentration of 1-5%, wherein the chitosan vaseline gauze has the functions of resisting bacteria, preserving moisture, stopping bleeding and promoting wound healing.

Disclosure of Invention

The technical problem to be solved by the invention is as follows: the traditional vaseline dressing is stored or used in a low-temperature environment, is easy to form blocks, has hard texture, low fitting property and low comfort after contacting with a wound surface, causes discomfort and pain of a patient, needs to be heated in advance and then used, has relatively long healing time of a chronic wound or an infected wound, and brings psychological burden and distress to the wound due to the peculiar smell often emitted by the wound when the traditional vaseline dressing is used. In order to solve the problems, the invention provides the deodorant dressing with high comfort and air permeability, which has a lower softening point, does not need preheating in use and has a normal use temperature as low as 5 ℃.

The technical scheme adopted by the invention for solving the technical problems is as follows:

the invention provides a deodorant dressing with high comfort and air permeability, which is characterized in that: the gauze comprises gauze and active ingredients, wherein the active ingredients comprise the following components in parts by weight:

100 portions of component A

0.1-10 parts of bismuth tribromophenate

1-10 parts of cyclodextrin

The component A comprises the following components in parts by weight:

70-90 parts of vaseline

8.9-10 parts of liquid paraffin.

Specifically, the cyclodextrin is α -cyclodextrin, β -cyclodextrin or gamma-cyclodextrin.

Specifically, the gauze is non-woven fabric, warp-knitted fabric, nile gauze or woven tape.

A preparation method of a deodorizing dressing with high comfort and air permeability is prepared according to the following steps:

(1) uniformly mixing the component A with bismuth tribromophenate and cyclodextrin for later use;

(2) coating the mixed solution obtained in the step (1) on gauze, wherein the coating amount of the gauze per square meter is 150-350 g;

(3) after coating, the gauze is folded to obtain the deodorant dressing with high comfort and air permeability.

The invention has the beneficial effects that:

(1) the hemostatic and deodorant dressing prepared by the invention has the advantages that the liquid paraffin is added into the vaseline, the integral softening point of the dressing is reduced, preheating is not needed during use, the normal use temperature is as low as 5 ℃, the hemostatic and deodorant dressing is very soft after being contacted with the skin, and a good comfortable feeling is provided for patients. In addition, the addition of the liquid paraffin also improves the permeability of the gauze in the effective component solution and increases the adhesive force of the vaseline on the gauze.

(2) The hemostatic and deodorant dressing prepared by the invention contains bismuth tribromophenate, which has certain hemostatic function, the bismuth tribromophenate is uniformly dispersed in vaseline and can be used for hemostasis of slight wound surface of nasal cavity, and the bismuth tribromophenate is beneficial to growth of skin; the strong and specific bromine element smell emitted by the bismuth tribromophenate can cover the foul smell emitted by chronic wounds, improve the wound environment, greatly reduce the possibility of secondary infection of wound surfaces and promote wound healing.

(3) The hemostatic and deodorant dressing prepared by the invention contains cyclodextrin, the cyclodextrin is a high molecular porous substance, and the cyclodextrin can absorb bad smell when added into the hemostatic and deodorant dressing, so that the psychological burden and the trouble of injury and patients are relieved.

(4) By adopting the modes of dip-coating and folding, the dressing coating uniformity and the folded attractiveness are ensured, and the production efficiency and the quality of the hemostatic and deodorant dressing are improved.

(5) The invention can ensure that the slurry is uniformly mixed without high-temperature heating and stirring, avoids volatile or toxic substances generated at high temperature, has simple process, reduces labor cost and environmental pollution, and is an economic, environment-friendly and practical medical dressing.

Detailed Description

The present invention will now be described in further detail with reference to examples.

Example 1

(1) 890g of vaseline and 89g of liquid paraffin are uniformly mixed for later use;

(2) taking 100g of the mixed solution obtained in the step (1), adding 1g of bismuth tribromophenate, and uniformly mixing;

(3) adding 10g of α -cyclodextrin into the mixed solution obtained in the step (2) to obtain mixed slurry;

(4) and (4) adding the mixed slurry obtained in the step (3) into a coating machine, impregnating gauze with coating slurry, coating 150g of slurry on each square meter of gauze, and folding after coating is finished to obtain the hemostatic and deodorant dressing.

Example 2

(1) 890g of vaseline and 89g of liquid paraffin are uniformly mixed for later use;

(2) taking 100g of the mixed solution obtained in the step (1), adding 1g of bismuth tribromophenate, and uniformly mixing;

(3) adding 10g of β -cyclodextrin into the mixed solution obtained in the step (2) to obtain mixed slurry;

(4) and (4) adding the mixed slurry obtained in the step (3) into a coating machine, impregnating gauze with coating slurry, coating 150g of slurry on each square meter of gauze, and folding after coating is finished to obtain the hemostatic and deodorant dressing.

Example 3

(1) 890g of vaseline and 89g of liquid paraffin are uniformly mixed for later use;

(2) taking 100g of the mixed solution obtained in the step (1), adding 10g of bismuth tribromophenate, and uniformly mixing;

(3) adding 10g of gamma-cyclodextrin into the mixed solution obtained in the step (2) to obtain mixed slurry;

(4) and (4) adding the mixed slurry obtained in the step (3) into a coating machine, impregnating gauze with coating slurry, coating 150g of slurry on each square meter of gauze, and folding after coating is finished to obtain the hemostatic and deodorant dressing.

Example 4

(1) Uniformly mixing 900g of vaseline and 100g of liquid paraffin;

(2) taking 100g of the mixed solution obtained in the step (1), adding 10g of bismuth tribromophenate, and uniformly mixing;

(3) adding 1g of α -cyclodextrin into the mixed solution obtained in the step (2) to obtain mixed slurry;

(4) and (4) adding the mixed slurry obtained in the step (3) into a coating machine, dipping the gauze by coating slurry, coating 200 g of slurry on each square meter of gauze, and folding after coating is finished to obtain the hemostatic and deodorant dressing.

Example 5

(1) Uniformly mixing 900g of vaseline and 89g of liquid paraffin;

(2) taking 100g of the mixed solution obtained in the step (1), adding 10g of bismuth tribromophenate, and uniformly mixing;

(3) adding 1g of α -cyclodextrin into the mixed solution obtained in the step (2) to obtain mixed slurry;

(4) and (4) adding the mixed slurry obtained in the step (3) into a coating machine, dipping the gauze by coating slurry, coating 250 g of slurry on each square meter of gauze, and folding after coating is finished to obtain the hemostatic and deodorant dressing.

Example 6

(1) Uniformly mixing 700g of vaseline and 89g of liquid paraffin;

(2) taking 100g of the mixed solution obtained in the step (1), adding 10g of bismuth tribromophenate, and uniformly mixing;

(3) adding 10g of α -cyclodextrin into the mixed solution obtained in the step (2) to obtain mixed slurry;

(4) and (4) adding the mixed slurry obtained in the step (3) into a coating machine, dipping the gauze by coating slurry, coating 300 g of slurry on each square meter of gauze, and folding after coating is finished to obtain the hemostatic and deodorant dressing.

Example 7

(1) Uniformly mixing 700g of vaseline and 100g of liquid paraffin;

(2) taking 100g of the mixed solution obtained in the step (1), adding 1g of bismuth tribromophenate, and uniformly mixing;

(3) adding 10g of α -cyclodextrin into the mixed solution obtained in the step (2) to obtain mixed slurry;

(4) and (4) adding the mixed slurry obtained in the step (3) into a coating machine, dipping gauze by coating slurry, coating 350g of slurry on each square meter of gauze, and folding after coating to obtain the hemostatic and deodorant dressing.

Comparative example 1 the same as in example 1 except that α -cyclodextrin was added in an amount of 20g in step (3).

Comparative example 2 differs from example 4 in that: the amount of the liquid paraffin added in step (1) was 150 g. With the increase of the addition amount of the liquid paraffin, the viscosity of the coating slurry is reduced, so that the bismuth tribromophenate and the cyclodextrin form precipitates in a mixed solution of the liquid paraffin and the vaseline, and finally the softness of the dressing is reduced, and specific test results are shown in table 1.

Comparative example 3 is the same as example 1 except that α -cyclodextrin was not added.

And (3) performance testing:

TABLE 1

The test data of comparative example 2 shows that as the amount of liquid paraffin added increases, the softness increases, but the viscosity of the coating slurry decreases, resulting in bismuth tribromophenate, cyclodextrin being prone to precipitate in the mixture of liquid paraffin with petrolatum.

Note: table 1 Water vapor transmission rates were tested according to YY/T0471.2-2004 contact wound dressing test method part 2: 0471; odor removal rate the rate of absorption of diethylamine gas by the dressing was tested according to YY/T0471 contact wound dressing test method part 6 odor control; softness was as per part 2 of the YY/T medical nonwoven compress test method: softness test in finished compress.

In light of the foregoing description of the preferred embodiment of the present invention, many modifications and variations will be apparent to those skilled in the art without departing from the spirit and scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.

Claims (4)

1. The utility model provides a high comfortable, gas permeability deodorization dressing which characterized in that: the gauze comprises gauze and active ingredients, wherein the active ingredients comprise the following components in parts by weight:

100 portions of component A

0.1-10 parts of bismuth tribromophenate

1-10 parts of cyclodextrin

The component A comprises the following components in parts by weight:

70-90 parts of vaseline

8.9-10 parts of liquid paraffin.

2. The deodorant dressing of claim 1, wherein the cyclodextrin is α -cyclodextrin, β -cyclodextrin or γ -cyclodextrin.

3. The highly comfortable, breathable deodorant dressing according to claim 1, wherein: the gauze is non-woven fabric, warp-knitted fabric, nile gauze or woven tape.

4. The preparation method of the deodorizing dressing with high comfort and air permeability is characterized by comprising the following steps:

(1) uniformly mixing the component A with bismuth tribromophenate and cyclodextrin for later use;

(2) coating the mixed solution obtained in the step (1) on gauze, wherein the coating amount of the gauze per square meter is 150-350 g;

(3) after coating, the gauze is folded to obtain the deodorant dressing with high comfort and air permeability.