CN108434504A - A kind of preparation method of Lipido-colloid dressing - Google Patents
A kind of preparation method of Lipido-colloid dressing Download PDFInfo
- Publication number
- CN108434504A CN108434504A CN201810393461.8A CN201810393461A CN108434504A CN 108434504 A CN108434504 A CN 108434504A CN 201810393461 A CN201810393461 A CN 201810393461A CN 108434504 A CN108434504 A CN 108434504A
- Authority
- CN
- China
- Prior art keywords
- lipido
- gel
- type vehicle
- preparation
- colloid dressing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of preparation methods of Lipido-colloid dressing, make gel-type vehicle by the low temperature emulsified mode of ultrasonic vacuum, and gel-type vehicle is spread evenly across on base material.The present invention makes gel-type vehicle by the low temperature emulsified mode of ultrasonic vacuum, and emulsifying effectiveness is more stable, extends the term of validity of Lipido-colloid dressing.Through the invention, the emulsifying effectiveness of Lipido-colloid dressing is more stable, and the decline degree of system viscosity is the 30% of prior art after emulsification；The term of validity extends 1 year than prior art.
Description
Technical field
The invention belongs to medical dressing technical fields, and in particular to a kind of preparation method of Lipido-colloid dressing.
Background technology
In medical product, paste and it is gelatinous be a kind of very common shape of product, but this kind of product is logical
The product that the normal term of validity is all not so good as solid state is long, and paste and gelatinous product are over time, it will usually with group
Product is caused to change at the aging of material, wherein a most important variation is exactly viscosity reduction, this problem is
Become a big difficulty of current such product.Lipido-colloid dressing is cured with made of substrate combination by lotion or gel-type vehicle
Product is treated, wherein lotion or gel-type vehicle have the longer term of validity in how realizing, it is that we need what is solved to ask at present
Topic.
Existing Lipido-colloid dressing carries out lotion or solidifying in such a way that use is dispersed with stirring, emulsifies or is stirred under vacuum
The making of gel matrix, stirring, emulsifying manner will produce the shearing force of high speed, which can be by the height in lotion or gel-type vehicle
Chain rupture, which occurs, for molecular material becomes small molecule, causes system viscosity to decline, the lotion after emulsification is unstable.
Invention content
The present invention provides a kind of preparation method of Lipido-colloid dressing, avoid lipid glue lotion or gel-type vehicle in breast
Viscosity is caused to decline due to by high shear during change.
In order to solve the above technical problems, the present invention adopts the following technical scheme that：A kind of preparation method of Lipido-colloid dressing,
Gel-type vehicle is made by the low temperature emulsified mode of ultrasonic vacuum, and gel-type vehicle is spread evenly across on base material.
Further, the low temperature emulsified ultrasonic power of the ultrasonic vacuum is 50-600W, and ultrasonic frequency is
10-40kHz, vacuum degree are -10-0.3MPa, and temperature is 0-25 DEG C.
Further, the gel-type vehicle is fine by vaseline, atoleine, sodium carboxymethylcellulose, cross-linked carboxymethyl
The plain sodium of dimension, JHA-21 emulsifiers composition；The weight percent of each component is in gel-type vehicle：Vaseline 75%-90%, atoleine
1%-8%, sodium carboxymethylcellulose 0.1%-5, croscarmellose sodium 0.1-2%, JHA-21 emulsifier 0.1%-5%.
Further, the base material includes following material：Polyurethane foam, PVA foams, cotton gauze, polyester gauze, alcohol
Sour fiber gauze, non-woven viscose fabric.
Beneficial effects of the present invention：The present invention makes gel-type vehicle by the low temperature emulsified mode of ultrasonic vacuum, emulsification
Effect is more stable, extends the term of validity of Lipido-colloid dressing.
Specific implementation mode
Technical scheme of the present invention will be clearly and completely described by specific implementation mode below.
Embodiment 1
Weigh 90g vaseline, 5g liquid paraffins, 2g sodium carboxymethylcelluloses, 2g croscarmellose sodiums, 1gJHA-21 breasts
Agent is placed in the low temperature emulsified equipment of ultrasonic vacuum, and setting ultrasonic frequency is 20kHz, vacuum degree is -1MPa, temperature 15
DEG C, gel-type vehicle is taken out in emulsification after sixty minutes, is coated on polyester gauze, cuts packaging sterilizing after the size of Cheng Suoxu.
Embodiment 2
Weigh 86g vaseline, 5g liquid paraffins, 5g sodium carboxymethylcelluloses, 2g croscarmellose sodiums, 2gJHA-21 breasts
Agent is placed in the low temperature emulsified equipment of ultrasonic vacuum, and setting ultrasonic frequency is 15kHz, vacuum degree is -0.5MPa, and temperature is
10 DEG C, gel-type vehicle is taken out in emulsification after sixty minutes, is coated on polyester gauze, cuts packaging sterilizing after the size of Cheng Suoxu.
Embodiment 3
Weigh 90g vaseline, 2g liquid paraffins, 3g sodium carboxymethylcelluloses, 1g croscarmellose sodiums, 2gJHA-21 breasts
Agent is placed in the low temperature emulsified equipment of ultrasonic vacuum, and setting ultrasonic frequency is 40kHz, vacuum degree 0.3MPa, and temperature is
20 DEG C, gel-type vehicle is taken out in emulsification after sixty minutes, is coated on polyester gauze, cuts packaging sterilizing after the size of Cheng Suoxu.
Embodiment described above is only that the preferred embodiment of the present invention is described, not to the design of the present invention
It is defined with range, under the premise of not departing from design concept of the present invention, ordinary engineering and technical personnel is to this hair in this field
The all variations and modifications that bright technical solution is made should all fall into protection scope of the present invention, claimed skill of the invention
Art content is all documented in technology claim.
Claims (4)
1. a kind of preparation method of Lipido-colloid dressing, it is characterised in that：It is made by the low temperature emulsified mode of ultrasonic vacuum
Gel-type vehicle, and gel-type vehicle is spread evenly across on base material.
2. a kind of preparation method of Lipido-colloid dressing according to claim, it is characterised in that：The ultrasonic wave is true
Empty low temperature emulsified ultrasonic power is 50-600W, and ultrasonic frequency 10-40kHz, vacuum degree is -10-0.3MPa, temperature
It is 0-25 DEG C.
3. a kind of preparation method of Lipido-colloid dressing according to claim 1, it is characterised in that：The gel-type vehicle
It is made of vaseline, atoleine, sodium carboxymethylcellulose, croscarmellose sodium, JHA-21 emulsifiers；Gel-type vehicle
The weight percent of middle each component is：Vaseline 75%-90%, atoleine 1%-8%, sodium carboxymethylcellulose 0.1%-5, crosslinking
Sodium carboxymethylcellulose 0.1-2%, JHA-21 emulsifier 0.1%-5%.
4. a kind of preparation method of Lipido-colloid dressing according to claim 1, it is characterised in that：The base material includes
One kind of following material：Polyurethane foam, PVA foams, cotton gauze, polyester gauze, alkyd fiber gauze, non-woven viscose fabric.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810393461.8A CN108434504A (en) | 2018-04-27 | 2018-04-27 | A kind of preparation method of Lipido-colloid dressing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810393461.8A CN108434504A (en) | 2018-04-27 | 2018-04-27 | A kind of preparation method of Lipido-colloid dressing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108434504A true CN108434504A (en) | 2018-08-24 |
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ID=63201855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810393461.8A Pending CN108434504A (en) | 2018-04-27 | 2018-04-27 | A kind of preparation method of Lipido-colloid dressing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108434504A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110917383A (en) * | 2019-12-31 | 2020-03-27 | 泰州市榕兴医疗用品股份有限公司 | Deodorizing dressing with high comfort and air permeability and preparation method thereof |
-
2018
- 2018-04-27 CN CN201810393461.8A patent/CN108434504A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110917383A (en) * | 2019-12-31 | 2020-03-27 | 泰州市榕兴医疗用品股份有限公司 | Deodorizing dressing with high comfort and air permeability and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180824 |