CN105688252A - Medical vaseline ointment gauze and manufacturing method thereof - Google Patents

Medical vaseline ointment gauze and manufacturing method thereof Download PDF

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Publication number
CN105688252A
CN105688252A CN201610156359.7A CN201610156359A CN105688252A CN 105688252 A CN105688252 A CN 105688252A CN 201610156359 A CN201610156359 A CN 201610156359A CN 105688252 A CN105688252 A CN 105688252A
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CN
China
Prior art keywords
ointment
gauze
medical
medical ventolin
manufacture method
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610156359.7A
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Chinese (zh)
Inventor
朱力
易志花
朱元国
俞慧丽
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Suzhou Jianyu Medical Technology Co Ltd
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Suzhou Jianyu Medical Technology Co Ltd
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Priority to CN201610156359.7A priority Critical patent/CN105688252A/en
Publication of CN105688252A publication Critical patent/CN105688252A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents

Abstract

The invention provides medical vaseline ointment gauze. Vaseline ointment is prepared by mixing medical vaseline, light liquid paraffin (white oil), effective components including CMC (sodium carboxymethylcellulose on the medical grade) and plant extract, an acid-base conditioning agent and the like, the vaseline ointment is added onto the gauze in a coating, or dipping or spraying mode to obtain the medical vaseline ointment gauze. The advantages of the effective components (CMC and the plant extract) and traditional Vaseline gauze are combined, and the novel clean and sanitary medical dressing with the functions of adsorption, permeation, preventing adhesion, preserving moisture, resisting bacterium and promoting wound healing is prepared.

Description

Medical ventolin ointment gauze and preparation method thereof
Technical field
The invention belongs to medical dressing field, be specifically related to a kind of medical ventolin ointment gauze and manufacture method。
Background technology
Vaseline gauze for medical use is used for preventing gauze and wound surface adhesion, has the effect of lubrication, viscous wound, promotion granulation growth, promotion wound healing。Be primarily adapted for use in the wrapping of burn property, non-infectious wound sticks wrapping use, and clinical application is very extensive。
Vaseline gauze for medical use in the market mostly is vaseline and paraffin oil makes miscella according to a certain percentage and is then applied to, and does not have anti-inflammation and absorbs effect of sepage。The present invention with the addition of magistery CMC with paraffin oil on the basis that vaseline mixes and plant proposes liquid, and plant extraction liquid is so as to have good antibacterial and anti-inflammation functions, and CMC is so as to have the effect absorbing sepage and moisturizing。
Summary of the invention
It is an object of the invention to provide the gauze of a kind of medical ventolin ointment, be a kind of advantage in conjunction with CMC with tradition kpetrolatum gauze, preparation is provided and is absorbed sepage, prevents adhesion, moisturizing antibacterial and promote the Medical dressing of wound healing function and clean hygiene。
The technical scheme is that and realize with following method:
The manufacture method of a kind of medical ventolin ointment gauze, is realized by following steps:
(1) vaseline ointment is prepared: medical ventolin and white oil are dissolved prior to 60~90 DEG C of heating, insulation;Under stirring, being slowly added to magistery, dispersed with stirring is uniform, it is to avoid caking;Adding pH adjusting agent is faintly acid or neutrality to ointment pH;
(2) vaseline ointment gauze is prepared: quantitatively made an addition on gauze by modes such as coating, dipping or sprays by the plaster prepared;
(3) overlay film cutting: by the kpetrolatum gauze both sides overlay film after cooling, shears, packing processes。
Further, the medical ventolin described in step (1) is mixed homogeneously with white oil, and weight ratio is 10~20:1。
Further, described medical ventolin adopts Yellow Vaselin or white vaseline。
Further, described white oil selects viscosity under 40 DEG C of conditions to be 5~30cp。
Further, the magistery described in step (1) is CMC and plant extract, and it is 0.1%~5% that described magistery CMC accounts for plaster weight percentage ranges, and it is 2%~5% that described magistery plant extract accounts for plaster weight percentage ranges。
Further, described pH adjusting agent is aqueous or oil-soluble organic acid, and described organic acid is the one in phosphoric acid, acetic acid。
Further, the gauze described in step (2), select medical cotton absorbent carbasus, can be 1~2 layer。
Further, described gauze, its ointment is 140~200g/m containing ointment weight range on gauze2
Further, the overlay film described in step (3), its material is any in PE, PP, PET, PU, and grammes per square metre ranges for 35~60g/m2
Present invention have the advantage that 1) CMC is dispersed in vaseline ointment and its performance fully demonstrated;2) with the addition of natural plant extraction liquid and add the effect of anti-inflammation;3) vaseline and white oil itself have moisture-keeping function, are conducive to wound healing;4) premium properties of tradition kpetrolatum gauze is remained: affinity is good, and moistening effect is good, flexible, breathable, and cost is low;5) making material simple, it is not necessary to complicated technology and high-end equipment, technique is simple, and cost is low, it is easy to promote。
Accompanying drawing explanation
Fig. 1 is the preparation technology flow process of product of the present invention。
Fig. 2 is CMC addition and the graph of a relation without expansion absorption amount。
Detailed description of the invention
Below in conjunction with drawings and Examples, the present invention made further elaboration。
Embodiment 1
The making of vaseline ointment gauze
Take medical ventolin and the heating for dissolving at 5g white oil and 60 DEG C of 95g, maintain the temperature at 60 DEG C and be slowly added to 0.5gCMC under stirring, be evenly stirred until dispersion without caking, then add 2g Flos Lonicerae extractive solution, stirring, adding acid-base modifier is 6 to ointment pH。Ointment is spread upon on the monolayer cotton absorbent carbasus of 30*50cm uniformly, after natural cooling, namely obtains the medical ventolin ointment gauze containing 0.5%CMC。
Embodiment 2
The making of vaseline ointment gauze
Taking medical ventolin and the heating for dissolving at 5g white oil and 90 DEG C of 95g, maintain the temperature at 90 DEG C and be slowly added to 1gCMC under stirring, be evenly stirred until dispersion without caking, then add 2g Fructus Canrii Albi extract, stir, adding acid-base modifier is 7.5 to ointment pH。Ointment is spread upon on the monolayer cotton absorbent carbasus of 30*50cm uniformly, after natural cooling, namely obtains the medical ventolin ointment gauze containing 1%CMC。
Embodiment 3
The making of vaseline ointment gauze
Take medical ventolin and the heating for dissolving at 5g white oil and 70 DEG C of 95g, maintain the temperature at 70 DEG C and be slowly added to 1.5gCMC under stirring, be evenly stirred until dispersion without caking, then add 2g Flos Lonicerae extractive solution, stirring, adding acid-base modifier is 4.5 to ointment pH。Ointment is spread upon on the monolayer cotton absorbent carbasus of 30*50cm uniformly, after natural cooling, namely obtains the medical ventolin ointment gauze containing 1.5%CMC。
Embodiment 4
The impact on absorbing sepage of the CMC Different adding amount
Experimental technique
Select containing each one of the medical ventolin sample that CMC is 0,0.5%, 1%, 1.5%, experiment successively through the following steps: the sample of known quality 5CM*5CM is placed in culture vessel, add the experiment liquid being preheated to 37 ± 1 DEG C, its quality is 40 times ± 0.5g of material to be tested, in immigration drying baker, at 37 ± 1 DEG C, keep 30min, clamp sample with tweezers, pendency 30s, weighs。
Experimental result CMC addition and the graph of a relation without expansion absorption amount are referring to Fig. 2
Sample without CMC is 0.5g/g without expansion absorption amount, and the sample containing 0.5%CMC is 1.1g/g without expansion absorption amount, and the sample containing 1%CMC is 1.4g/g without expansion absorption amount, and the sample containing 1.5%CMC is 1.6g/g without expansion absorption amount。
By it is shown that CMC can significantly improve the absorbability of wound exudate, being 0.5g/g without expansion absorption amount when being not added with CMC, during 1% addition, its absorbtivity is 1.4g/g, about 3 times during for being not added with。

Claims (9)

1. the manufacture method of a medical ventolin ointment gauze, it is characterised in that realized by following steps:
(1) vaseline ointment is prepared: medical ventolin and white oil are dissolved prior to 60~90 DEG C of heating, insulation;Under stirring, being slowly added to magistery, dispersed with stirring is uniform, it is to avoid caking;Adding pH adjusting agent is faintly acid or neutrality to ointment pH;
(2) vaseline ointment gauze is prepared: quantitatively made an addition on gauze by modes such as coating, dipping or sprays by the plaster prepared;
(3) overlay film cutting: by the kpetrolatum gauze both sides overlay film after cooling, shears, packing processes。
2. the manufacture method of medical ventolin ointment gauze according to claim 1, it is characterised in that the medical ventolin described in step (1) is mixed homogeneously with white oil, and weight ratio is 10~20:1。
3. the manufacture method of the medical ventolin ointment gauze according to claims 1 or 2, it is characterised in that described medical ventolin adopts Yellow Vaselin or white vaseline。
4. the manufacture method of the medical ventolin ointment gauze according to claims 1 or 2, it is characterised in that described white oil selects viscosity under 40 DEG C of conditions to be 5~30cp。
5. the manufacture method of medical ventolin ointment gauze according to claim 1, it is characterized in that, magistery described in step (1) is CMC and plant extract, it is 0.1%~5% that described magistery CMC accounts for plaster weight percentage ranges, and it is 2%~5% that described magistery plant extract accounts for plaster weight percentage ranges。
6. the manufacture method of medical ventolin ointment gauze according to claim 1, it is characterised in that described pH adjusting agent is aqueous or oil-soluble organic acid, and described organic acid is the one in phosphoric acid, acetic acid。
7. the manufacture method of medical ventolin ointment gauze according to claim 1, it is characterised in that the gauze described in step (2), selects medical cotton absorbent carbasus, can be 1~2 layer。
8. the manufacture method of the medical ventolin ointment gauze according to claim 1 or 7, it is characterised in that described gauze, its ointment is 140~200g/m containing ointment weight range on gauze2
9. the manufacture method of medical ventolin ointment gauze according to claim 1, it is characterised in that the overlay film described in step (3), its material is any in PE, PP, PET, PU, and grammes per square metre ranges for 35~60g/m2
CN201610156359.7A 2016-03-18 2016-03-18 Medical vaseline ointment gauze and manufacturing method thereof Pending CN105688252A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109395143A (en) * 2018-10-16 2019-03-01 广州润虹医药科技股份有限公司 A kind of antiseptic anti-adhesion hydrocolloid oil yarn and preparation method thereof
CN110917383A (en) * 2019-12-31 2020-03-27 泰州市榕兴医疗用品股份有限公司 Deodorizing dressing with high comfort and air permeability and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1686573A (en) * 2005-05-13 2005-10-26 褚省吾 Lipid hydro colloid polymer anti bacterial dressing and its preparation method
CN1947756A (en) * 2005-10-13 2007-04-18 冯耀宗 Formula of seven herbs medicine composition for relieving internal heat and invigorating blood circulation, its prepn. process and use
CN102784411A (en) * 2011-05-19 2012-11-21 L&R国际有限责任及两合公司 Wound dressing
CN103445912A (en) * 2013-05-24 2013-12-18 海安县美佳卫生用品有限公司 Vaseline oil gauze producing method
CN104491918A (en) * 2015-01-07 2015-04-08 何欣 Novel antibacterial hydrocolloid dressing and preparation method thereof
CN105213637A (en) * 2015-10-16 2016-01-06 辛秋莲 A kind of for epidemic victim's wound disinfection nursing powder and preparation method thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1686573A (en) * 2005-05-13 2005-10-26 褚省吾 Lipid hydro colloid polymer anti bacterial dressing and its preparation method
CN1947756A (en) * 2005-10-13 2007-04-18 冯耀宗 Formula of seven herbs medicine composition for relieving internal heat and invigorating blood circulation, its prepn. process and use
CN102784411A (en) * 2011-05-19 2012-11-21 L&R国际有限责任及两合公司 Wound dressing
CN103445912A (en) * 2013-05-24 2013-12-18 海安县美佳卫生用品有限公司 Vaseline oil gauze producing method
CN104491918A (en) * 2015-01-07 2015-04-08 何欣 Novel antibacterial hydrocolloid dressing and preparation method thereof
CN105213637A (en) * 2015-10-16 2016-01-06 辛秋莲 A kind of for epidemic victim's wound disinfection nursing powder and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109395143A (en) * 2018-10-16 2019-03-01 广州润虹医药科技股份有限公司 A kind of antiseptic anti-adhesion hydrocolloid oil yarn and preparation method thereof
CN109395143B (en) * 2018-10-16 2021-06-01 广州润虹医药科技股份有限公司 Antibacterial anti-adhesion hydrocolloid oily yarn and preparation method thereof
CN110917383A (en) * 2019-12-31 2020-03-27 泰州市榕兴医疗用品股份有限公司 Deodorizing dressing with high comfort and air permeability and preparation method thereof

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Application publication date: 20160622

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