CN110891617A - 抗微生物或伤口护理材料、装置和用途 - Google Patents
抗微生物或伤口护理材料、装置和用途 Download PDFInfo
- Publication number
- CN110891617A CN110891617A CN201880046565.XA CN201880046565A CN110891617A CN 110891617 A CN110891617 A CN 110891617A CN 201880046565 A CN201880046565 A CN 201880046565A CN 110891617 A CN110891617 A CN 110891617A
- Authority
- CN
- China
- Prior art keywords
- wound
- layer
- powder charge
- matrix
- silver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000463 material Substances 0.000 title claims abstract description 320
- 230000000845 anti-microbial effect Effects 0.000 title claims abstract description 158
- 239000000843 powder Substances 0.000 claims abstract description 342
- 239000011159 matrix material Substances 0.000 claims abstract description 301
- 239000000654 additive Substances 0.000 claims abstract description 232
- 239000006260 foam Substances 0.000 claims abstract description 173
- 238000000034 method Methods 0.000 claims abstract description 166
- 230000000996 additive effect Effects 0.000 claims abstract description 151
- 239000000758 substrate Substances 0.000 claims abstract description 123
- 239000011148 porous material Substances 0.000 claims abstract description 78
- 239000004599 antimicrobial Substances 0.000 claims abstract description 51
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 46
- 239000002131 composite material Substances 0.000 claims abstract description 32
- 239000011230 binding agent Substances 0.000 claims abstract description 29
- 230000002441 reversible effect Effects 0.000 claims abstract description 27
- 238000004519 manufacturing process Methods 0.000 claims abstract description 23
- 239000000203 mixture Substances 0.000 claims abstract description 20
- 239000004067 bulking agent Substances 0.000 claims abstract description 6
- 239000002250 absorbent Substances 0.000 claims description 246
- 230000002745 absorbent Effects 0.000 claims description 244
- 239000012530 fluid Substances 0.000 claims description 150
- 239000002245 particle Substances 0.000 claims description 95
- 210000000416 exudates and transudate Anatomy 0.000 claims description 81
- 239000000835 fiber Substances 0.000 claims description 81
- 229910052709 silver Inorganic materials 0.000 claims description 70
- 239000004332 silver Substances 0.000 claims description 70
- YPNVIBVEFVRZPJ-UHFFFAOYSA-L silver sulfate Chemical compound [Ag+].[Ag+].[O-]S([O-])(=O)=O YPNVIBVEFVRZPJ-UHFFFAOYSA-L 0.000 claims description 68
- 229910000367 silver sulfate Inorganic materials 0.000 claims description 68
- 239000000126 substance Substances 0.000 claims description 51
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 47
- 239000000853 adhesive Substances 0.000 claims description 40
- 230000001070 adhesive effect Effects 0.000 claims description 40
- 230000000873 masking effect Effects 0.000 claims description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 36
- 229920005830 Polyurethane Foam Polymers 0.000 claims description 35
- -1 structural proppants Substances 0.000 claims description 34
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 30
- 150000003378 silver Chemical class 0.000 claims description 30
- 239000004606 Fillers/Extenders Substances 0.000 claims description 29
- 230000008569 process Effects 0.000 claims description 28
- 239000004814 polyurethane Substances 0.000 claims description 23
- 229920000642 polymer Polymers 0.000 claims description 22
- 229920000247 superabsorbent polymer Polymers 0.000 claims description 20
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 18
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 claims description 18
- 239000012736 aqueous medium Substances 0.000 claims description 17
- 229920001477 hydrophilic polymer Polymers 0.000 claims description 15
- 229920002635 polyurethane Polymers 0.000 claims description 15
- 230000036961 partial effect Effects 0.000 claims description 14
- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 claims description 14
- 230000001954 sterilising effect Effects 0.000 claims description 14
- 238000004659 sterilization and disinfection Methods 0.000 claims description 14
- 230000006870 function Effects 0.000 claims description 13
- 238000005507 spraying Methods 0.000 claims description 13
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 12
- 229920000297 Rayon Polymers 0.000 claims description 12
- 239000003610 charcoal Substances 0.000 claims description 12
- 229910052740 iodine Inorganic materials 0.000 claims description 12
- 239000011630 iodine Substances 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 12
- 239000000377 silicon dioxide Substances 0.000 claims description 12
- 239000004583 superabsorbent polymers (SAPs) Substances 0.000 claims description 12
- 230000007423 decrease Effects 0.000 claims description 11
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims description 10
- 244000005700 microbiome Species 0.000 claims description 10
- 229920001223 polyethylene glycol Polymers 0.000 claims description 10
- 239000007787 solid Substances 0.000 claims description 10
- 229920000573 polyethylene Polymers 0.000 claims description 9
- 229910001961 silver nitrate Inorganic materials 0.000 claims description 9
- 229960003600 silver sulfadiazine Drugs 0.000 claims description 9
- UEJSSZHHYBHCEL-UHFFFAOYSA-N silver(1+) sulfadiazinate Chemical compound [Ag+].C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1 UEJSSZHHYBHCEL-UHFFFAOYSA-N 0.000 claims description 9
- 230000001580 bacterial effect Effects 0.000 claims description 8
- 230000004888 barrier function Effects 0.000 claims description 8
- 229920002678 cellulose Polymers 0.000 claims description 8
- 239000001913 cellulose Substances 0.000 claims description 8
- ZXSQEZNORDWBGZ-UHFFFAOYSA-N 1,3-dihydropyrrolo[2,3-b]pyridin-2-one Chemical compound C1=CN=C2NC(=O)CC2=C1 ZXSQEZNORDWBGZ-UHFFFAOYSA-N 0.000 claims description 7
- 229910021607 Silver chloride Inorganic materials 0.000 claims description 7
- 229910021536 Zeolite Inorganic materials 0.000 claims description 7
- 239000003086 colorant Substances 0.000 claims description 7
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 7
- 238000007726 management method Methods 0.000 claims description 7
- 239000002609 medium Substances 0.000 claims description 7
- 238000004806 packaging method and process Methods 0.000 claims description 7
- 238000005096 rolling process Methods 0.000 claims description 7
- CQLFBEKRDQMJLZ-UHFFFAOYSA-M silver acetate Chemical compound [Ag+].CC([O-])=O CQLFBEKRDQMJLZ-UHFFFAOYSA-M 0.000 claims description 7
- 229940071536 silver acetate Drugs 0.000 claims description 7
- 229910001958 silver carbonate Inorganic materials 0.000 claims description 7
- LKZMBDSASOBTPN-UHFFFAOYSA-L silver carbonate Substances [Ag].[O-]C([O-])=O LKZMBDSASOBTPN-UHFFFAOYSA-L 0.000 claims description 7
- 229940071575 silver citrate Drugs 0.000 claims description 7
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 claims description 7
- 229910001923 silver oxide Inorganic materials 0.000 claims description 7
- LMEWRZSPCQHBOB-UHFFFAOYSA-M silver;2-hydroxypropanoate Chemical compound [Ag+].CC(O)C([O-])=O LMEWRZSPCQHBOB-UHFFFAOYSA-M 0.000 claims description 7
- 241000894007 species Species 0.000 claims description 7
- QUTYHQJYVDNJJA-UHFFFAOYSA-K trisilver;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Ag+].[Ag+].[Ag+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QUTYHQJYVDNJJA-UHFFFAOYSA-K 0.000 claims description 7
- 239000010457 zeolite Substances 0.000 claims description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 6
- 239000004927 clay Substances 0.000 claims description 6
- 235000013305 food Nutrition 0.000 claims description 6
- 239000010439 graphite Substances 0.000 claims description 6
- 229910002804 graphite Inorganic materials 0.000 claims description 6
- 230000036541 health Effects 0.000 claims description 6
- 230000000813 microbial effect Effects 0.000 claims description 6
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 6
- FJOLTQXXWSRAIX-UHFFFAOYSA-K silver phosphate Chemical compound [Ag+].[Ag+].[Ag+].[O-]P([O-])([O-])=O FJOLTQXXWSRAIX-UHFFFAOYSA-K 0.000 claims description 6
- 229910000161 silver phosphate Inorganic materials 0.000 claims description 6
- 229940019931 silver phosphate Drugs 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 5
- 230000003247 decreasing effect Effects 0.000 claims description 5
- 238000009792 diffusion process Methods 0.000 claims description 5
- 230000005686 electrostatic field Effects 0.000 claims description 5
- 208000015181 infectious disease Diseases 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 239000004800 polyvinyl chloride Substances 0.000 claims description 5
- 229920000915 polyvinyl chloride Polymers 0.000 claims description 5
- 230000000717 retained effect Effects 0.000 claims description 5
- 238000013268 sustained release Methods 0.000 claims description 5
- 239000012730 sustained-release form Substances 0.000 claims description 5
- 238000009423 ventilation Methods 0.000 claims description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 4
- 239000000022 bacteriostatic agent Substances 0.000 claims description 4
- 229920001971 elastomer Polymers 0.000 claims description 4
- 230000005684 electric field Effects 0.000 claims description 4
- 239000000499 gel Substances 0.000 claims description 4
- 230000003020 moisturizing effect Effects 0.000 claims description 4
- 238000010951 particle size reduction Methods 0.000 claims description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 4
- 230000000153 supplemental effect Effects 0.000 claims description 4
- 239000000440 bentonite Substances 0.000 claims description 3
- 229910000278 bentonite Inorganic materials 0.000 claims description 3
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims description 3
- 229920001577 copolymer Polymers 0.000 claims description 3
- 230000005484 gravity Effects 0.000 claims description 3
- 230000003287 optical effect Effects 0.000 claims description 3
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 3
- 229920006254 polymer film Polymers 0.000 claims description 3
- 239000002964 rayon Substances 0.000 claims description 3
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical group [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 3
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims description 2
- 229920002101 Chitin Polymers 0.000 claims description 2
- 229920001661 Chitosan Polymers 0.000 claims description 2
- 229920002785 Croscarmellose sodium Polymers 0.000 claims description 2
- 239000004793 Polystyrene Substances 0.000 claims description 2
- 238000001467 acupuncture Methods 0.000 claims description 2
- 229940072056 alginate Drugs 0.000 claims description 2
- 229920000615 alginic acid Polymers 0.000 claims description 2
- 235000010443 alginic acid Nutrition 0.000 claims description 2
- 239000003963 antioxidant agent Substances 0.000 claims description 2
- 239000006258 conductive agent Substances 0.000 claims description 2
- 239000002537 cosmetic Substances 0.000 claims description 2
- 229920003020 cross-linked polyethylene Polymers 0.000 claims description 2
- 239000004703 cross-linked polyethylene Substances 0.000 claims description 2
- 239000003398 denaturant Substances 0.000 claims description 2
- 239000000806 elastomer Substances 0.000 claims description 2
- 239000003063 flame retardant Substances 0.000 claims description 2
- 239000012628 flowing agent Substances 0.000 claims description 2
- 229920005615 natural polymer Polymers 0.000 claims description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 2
- 229920000098 polyolefin Polymers 0.000 claims description 2
- 229920002223 polystyrene Polymers 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 claims description 2
- 108090000623 proteins and genes Proteins 0.000 claims description 2
- 238000000926 separation method Methods 0.000 claims description 2
- 238000007873 sieving Methods 0.000 claims description 2
- 229920001059 synthetic polymer Polymers 0.000 claims description 2
- 229920001169 thermoplastic Polymers 0.000 claims description 2
- 238000004383 yellowing Methods 0.000 claims description 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- 229960001631 carbomer Drugs 0.000 claims 2
- 229940098458 powder spray Drugs 0.000 claims 2
- SYWDWCWQXBUCOP-UHFFFAOYSA-N benzene;ethene Chemical group C=C.C1=CC=CC=C1 SYWDWCWQXBUCOP-UHFFFAOYSA-N 0.000 claims 1
- 230000021523 carboxylation Effects 0.000 claims 1
- 238000006473 carboxylation reaction Methods 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- NDYNABNWLRVCDO-UHFFFAOYSA-N phosphoric acid silver Chemical compound [Ag].P(O)(O)(O)=O NDYNABNWLRVCDO-UHFFFAOYSA-N 0.000 claims 1
- 238000006277 sulfonation reaction Methods 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 238000009826 distribution Methods 0.000 abstract description 25
- 230000001413 cellular effect Effects 0.000 abstract description 6
- 239000010410 layer Substances 0.000 description 988
- 206010052428 Wound Diseases 0.000 description 706
- 208000027418 Wounds and injury Diseases 0.000 description 705
- 210000004027 cell Anatomy 0.000 description 173
- 230000005540 biological transmission Effects 0.000 description 85
- 239000007788 liquid Substances 0.000 description 48
- 238000011068 loading method Methods 0.000 description 42
- 239000012790 adhesive layer Substances 0.000 description 24
- 239000007789 gas Substances 0.000 description 24
- 239000011496 polyurethane foam Substances 0.000 description 23
- 239000012528 membrane Substances 0.000 description 22
- 239000006096 absorbing agent Substances 0.000 description 17
- 238000010521 absorption reaction Methods 0.000 description 17
- 238000009581 negative-pressure wound therapy Methods 0.000 description 17
- 125000006850 spacer group Chemical group 0.000 description 16
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 12
- 229920000728 polyester Polymers 0.000 description 12
- 230000002829 reductive effect Effects 0.000 description 11
- 210000001519 tissue Anatomy 0.000 description 11
- 239000004744 fabric Substances 0.000 description 10
- 230000035699 permeability Effects 0.000 description 10
- 229920006264 polyurethane film Polymers 0.000 description 10
- 230000005284 excitation Effects 0.000 description 9
- 239000011164 primary particle Substances 0.000 description 9
- 238000012545 processing Methods 0.000 description 9
- 238000012546 transfer Methods 0.000 description 9
- 239000004698 Polyethylene Substances 0.000 description 8
- 238000004891 communication Methods 0.000 description 8
- 238000003475 lamination Methods 0.000 description 8
- 239000000243 solution Substances 0.000 description 8
- 239000013589 supplement Substances 0.000 description 8
- 230000009471 action Effects 0.000 description 7
- 238000005266 casting Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 230000008018 melting Effects 0.000 description 7
- 238000002844 melting Methods 0.000 description 7
- 229920001296 polysiloxane Polymers 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 238000001035 drying Methods 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 150000003839 salts Chemical class 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 239000004831 Hot glue Substances 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 239000007900 aqueous suspension Substances 0.000 description 5
- 230000000903 blocking effect Effects 0.000 description 5
- 230000001684 chronic effect Effects 0.000 description 5
- 238000011109 contamination Methods 0.000 description 5
- 238000000227 grinding Methods 0.000 description 5
- 238000005470 impregnation Methods 0.000 description 5
- 239000004745 nonwoven fabric Substances 0.000 description 5
- 239000012071 phase Substances 0.000 description 5
- 238000006116 polymerization reaction Methods 0.000 description 5
- 238000001878 scanning electron micrograph Methods 0.000 description 5
- 239000011163 secondary particle Substances 0.000 description 5
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical class [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 description 5
- 229920002994 synthetic fiber Polymers 0.000 description 5
- 238000013519 translation Methods 0.000 description 5
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 4
- 208000004210 Pressure Ulcer Diseases 0.000 description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 4
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- JKNZUZCGFROMAZ-UHFFFAOYSA-L [Ag+2].[O-]S([O-])(=O)=O Chemical compound [Ag+2].[O-]S([O-])(=O)=O JKNZUZCGFROMAZ-UHFFFAOYSA-L 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 238000000151 deposition Methods 0.000 description 4
- 238000005243 fluidization Methods 0.000 description 4
- 230000035876 healing Effects 0.000 description 4
- 230000002209 hydrophobic effect Effects 0.000 description 4
- 230000014759 maintenance of location Effects 0.000 description 4
- 239000011325 microbead Substances 0.000 description 4
- 235000019645 odor Nutrition 0.000 description 4
- 230000004224 protection Effects 0.000 description 4
- 239000011780 sodium chloride Substances 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 229910052721 tungsten Inorganic materials 0.000 description 4
- 230000029663 wound healing Effects 0.000 description 4
- 229920006347 Elastollan Polymers 0.000 description 3
- 241000233866 Fungi Species 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 239000003522 acrylic cement Substances 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 230000003385 bacteriostatic effect Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 238000002591 computed tomography Methods 0.000 description 3
- 238000010924 continuous production Methods 0.000 description 3
- 239000000975 dye Substances 0.000 description 3
- 239000002657 fibrous material Substances 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
- 229910021485 fumed silica Inorganic materials 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 230000002147 killing effect Effects 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 239000007791 liquid phase Substances 0.000 description 3
- 238000012423 maintenance Methods 0.000 description 3
- 238000003801 milling Methods 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 238000011002 quantification Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 229910002027 silica gel Inorganic materials 0.000 description 3
- 239000000741 silica gel Substances 0.000 description 3
- 230000000087 stabilizing effect Effects 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000007794 visualization technique Methods 0.000 description 3
- 238000003466 welding Methods 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 102000029816 Collagenase Human genes 0.000 description 2
- 108060005980 Collagenase Proteins 0.000 description 2
- 208000034656 Contusions Diseases 0.000 description 2
- 229920001651 Cyanoacrylate Polymers 0.000 description 2
- 241000192700 Cyanobacteria Species 0.000 description 2
- 206010056340 Diabetic ulcer Diseases 0.000 description 2
- 239000004593 Epoxy Substances 0.000 description 2
- 241000192125 Firmicutes Species 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 229940124761 MMP inhibitor Drugs 0.000 description 2
- MWCLLHOVUTZFKS-UHFFFAOYSA-N Methyl cyanoacrylate Chemical compound COC(=O)C(=C)C#N MWCLLHOVUTZFKS-UHFFFAOYSA-N 0.000 description 2
- 241000191992 Peptostreptococcus Species 0.000 description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 208000002847 Surgical Wound Diseases 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 208000000558 Varicose Ulcer Diseases 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 2
- 230000000843 anti-fungal effect Effects 0.000 description 2
- 229940121375 antifungal agent Drugs 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 210000002421 cell wall Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 229960002424 collagenase Drugs 0.000 description 2
- 230000009519 contusion Effects 0.000 description 2
- 230000001186 cumulative effect Effects 0.000 description 2
- 238000001804 debridement Methods 0.000 description 2
- 239000010432 diamond Substances 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000010894 electron beam technology Methods 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 230000036074 healthy skin Effects 0.000 description 2
- 230000036571 hydration Effects 0.000 description 2
- 238000006703 hydration reaction Methods 0.000 description 2
- 238000010191 image analysis Methods 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 239000012948 isocyanate Substances 0.000 description 2
- 150000002513 isocyanates Chemical class 0.000 description 2
- 238000010902 jet-milling Methods 0.000 description 2
- 239000000155 melt Substances 0.000 description 2
- 239000013618 particulate matter Substances 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 238000007639 printing Methods 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 229920006395 saturated elastomer Polymers 0.000 description 2
- 230000011218 segmentation Effects 0.000 description 2
- 239000007790 solid phase Substances 0.000 description 2
- 239000012209 synthetic fiber Substances 0.000 description 2
- 238000009823 thermal lamination Methods 0.000 description 2
- 238000012876 topography Methods 0.000 description 2
- 230000005068 transpiration Effects 0.000 description 2
- 230000008733 trauma Effects 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 238000012800 visualization Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- JKXYOQDLERSFPT-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-octadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO JKXYOQDLERSFPT-UHFFFAOYSA-N 0.000 description 1
- KUDUQBURMYMBIJ-UHFFFAOYSA-N 2-prop-2-enoyloxyethyl prop-2-enoate Chemical compound C=CC(=O)OCCOC(=O)C=C KUDUQBURMYMBIJ-UHFFFAOYSA-N 0.000 description 1
- 241000589291 Acinetobacter Species 0.000 description 1
- 241000186046 Actinomyces Species 0.000 description 1
- 244000034356 Aframomum angustifolium Species 0.000 description 1
- 241000606125 Bacteroides Species 0.000 description 1
- 241000606124 Bacteroides fragilis Species 0.000 description 1
- 241000186000 Bifidobacterium Species 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 206010006797 Burns first degree Diseases 0.000 description 1
- 206010006802 Burns second degree Diseases 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 229920003043 Cellulose fiber Polymers 0.000 description 1
- 241000284156 Clerodendrum quadriloculare Species 0.000 description 1
- 241000193163 Clostridioides difficile Species 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 241000186216 Corynebacterium Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 208000008960 Diabetic foot Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000588921 Enterobacteriaceae Species 0.000 description 1
- 241000194033 Enterococcus Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 208000035874 Excoriation Diseases 0.000 description 1
- 206010016717 Fistula Diseases 0.000 description 1
- 241000605909 Fusobacterium Species 0.000 description 1
- 241000588748 Klebsiella Species 0.000 description 1
- 208000034693 Laceration Diseases 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- 208000005230 Leg Ulcer Diseases 0.000 description 1
- 241000589248 Legionella Species 0.000 description 1
- 208000007764 Legionnaires' Disease Diseases 0.000 description 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 description 1
- 208000004221 Multiple Trauma Diseases 0.000 description 1
- 241000588653 Neisseria Species 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 229920002562 Polyethylene Glycol 3350 Polymers 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920002413 Polyhexanide Polymers 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 241000605894 Porphyromonas Species 0.000 description 1
- 241000605861 Prevotella Species 0.000 description 1
- 241000186429 Propionibacterium Species 0.000 description 1
- 241000192142 Proteobacteria Species 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 238000001530 Raman microscopy Methods 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 241000607768 Shigella Species 0.000 description 1
- 241001180364 Spirochaetes Species 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000004433 Thermoplastic polyurethane Substances 0.000 description 1
- 206010044546 Traumatic ulcer Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 241001148470 aerobic bacillus Species 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 239000005030 aluminium foil Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000656 anti-yeast Effects 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000010923 batch production Methods 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229960005376 cadexomer iodine Drugs 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 229960003333 chlorhexidine gluconate Drugs 0.000 description 1
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000011538 cleaning material Substances 0.000 description 1
- 230000008045 co-localization Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 150000001879 copper Chemical class 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 238000004042 decolorization Methods 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000023753 dehiscence Effects 0.000 description 1
- 238000002716 delivery method Methods 0.000 description 1
- 239000005548 dental material Substances 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000003989 dielectric material Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000009837 dry grinding Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 238000011067 equilibration Methods 0.000 description 1
- 239000005038 ethylene vinyl acetate Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 230000003890 fistula Effects 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 230000001408 fungistatic effect Effects 0.000 description 1
- 230000037313 granulation tissue formation Effects 0.000 description 1
- 239000008233 hard water Substances 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 239000012943 hotmelt Substances 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000000976 ink Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000009830 intercalation Methods 0.000 description 1
- 230000002687 intercalation Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 238000000608 laser ablation Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 238000002803 maceration Methods 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 239000008204 material by function Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 229960003085 meticillin Drugs 0.000 description 1
- 239000010445 mica Substances 0.000 description 1
- 229910052618 mica group Inorganic materials 0.000 description 1
- 238000010603 microCT Methods 0.000 description 1
- 238000012009 microbiological test Methods 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229910052901 montmorillonite Inorganic materials 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 238000004091 panning Methods 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011946 reduction process Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 238000004626 scanning electron microscopy Methods 0.000 description 1
- 238000005204 segregation Methods 0.000 description 1
- 239000013464 silicone adhesive Substances 0.000 description 1
- 229940054334 silver cation Drugs 0.000 description 1
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical class [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229920002803 thermoplastic polyurethane Polymers 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 239000004034 viscosity adjusting agent Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 230000010388 wound contraction Effects 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
- 238000004876 x-ray fluorescence Methods 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1711183.2A GB201711183D0 (en) | 2017-07-12 | 2017-07-12 | Antimicrobial or wound care materials, devices and uses |
| GB1711183.2 | 2017-07-12 | ||
| PCT/EP2018/069015 WO2019012069A1 (en) | 2017-07-12 | 2018-07-12 | ANTIMICROBIAL OR WOUND CARE MATERIALS, DEVICES AND USES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110891617A true CN110891617A (zh) | 2020-03-17 |
Family
ID=59676688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880046565.XA Pending CN110891617A (zh) | 2017-07-12 | 2018-07-12 | 抗微生物或伤口护理材料、装置和用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11730852B2 (enExample) |
| EP (2) | EP4353271A1 (enExample) |
| JP (1) | JP7712764B2 (enExample) |
| CN (1) | CN110891617A (enExample) |
| AU (2) | AU2018300759B2 (enExample) |
| CA (1) | CA3069284A1 (enExample) |
| GB (1) | GB201711183D0 (enExample) |
| SG (1) | SG11201912597SA (enExample) |
| WO (1) | WO2019012069A1 (enExample) |
| ZA (1) | ZA201908504B (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111346255A (zh) * | 2020-04-21 | 2020-06-30 | 四川大学 | 兼具抗菌和带菌警示功能的伤口敷料及其制备方法 |
| CN115463270A (zh) * | 2022-09-13 | 2022-12-13 | 湖北世丰新材料有限公司 | 一种负压引流医用海绵及其制备方法 |
| CN115990284A (zh) * | 2023-01-06 | 2023-04-21 | 杭州沸创生命科技股份有限公司 | 一种止血纱布涂布用的浆料及利用其制备的止血纱布 |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| EP4162968A1 (en) | 2010-12-08 | 2023-04-12 | ConvaTec Technologies Inc. | System for removing exudates from a wound site |
| CN103347561B (zh) | 2010-12-08 | 2016-09-07 | 康沃特克科技公司 | 用于评估伤口分泌液的集成系统 |
| JP6151186B2 (ja) | 2010-12-08 | 2017-06-21 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 創傷滲出液システム付属装置 |
| GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
| GB2497406A (en) | 2011-11-29 | 2013-06-12 | Webtec Converting Llc | Dressing with a perforated binder layer |
| CN105008611A (zh) | 2012-12-20 | 2015-10-28 | 康沃特克科技公司 | 化学改性的纤维素纤维的处理 |
| GB2543544A (en) | 2015-10-21 | 2017-04-26 | Brightwake Ltd | Wound dressing |
| CN109310528B (zh) | 2016-03-30 | 2021-07-20 | 康沃特克科技公司 | 检测伤口中的微生物感染 |
| CA3019436A1 (en) | 2016-03-30 | 2017-10-05 | Qualizyme Diagnostics Gmbh & Co Kg | Detecting microbial infection in wounds |
| GB201608099D0 (en) | 2016-05-09 | 2016-06-22 | Convatec Technologies Inc | Negative pressure wound dressing |
| PL3481360T3 (pl) | 2016-07-08 | 2022-05-02 | Convatec Technologies Inc. | Wykrywanie przepływu płynu |
| TW201805034A (zh) | 2016-07-08 | 2018-02-16 | 美商康瓦鐵克科技股份有限公司 | 彈性的負壓系統 |
| US11266774B2 (en) | 2016-07-08 | 2022-03-08 | Convatec Technologies Inc. | Fluid collection apparatus |
| GB201711181D0 (en) | 2017-07-12 | 2017-08-23 | Smith & Nephew | Polymer foam material, device and use |
| GB201711179D0 (en) | 2017-07-12 | 2017-08-23 | Smith & Nephew | Wound care materials, devices and uses |
| GB201711183D0 (en) | 2017-07-12 | 2017-08-23 | Smith & Nephew | Antimicrobial or wound care materials, devices and uses |
| EP3703633B2 (en) | 2017-11-03 | 2024-06-26 | 3M Innovative Properties Company | Extended wear-time dressing |
| US12161792B2 (en) | 2017-11-16 | 2024-12-10 | Convatec Limited | Fluid collection apparatus |
| EP3843678B1 (en) * | 2018-08-28 | 2023-07-26 | KCI Licensing, Inc. | Dressings for reduced tissue ingrowth |
| US12123835B2 (en) * | 2018-11-29 | 2024-10-22 | Basf Se | Prediction of physical properties of superabsorbent polymers |
| JP7511585B2 (ja) | 2019-06-03 | 2024-07-05 | コンバテック リミティド | 病原体を破壊して封じ込めるための方法およびデバイス |
| CN110591531A (zh) * | 2019-09-25 | 2019-12-20 | 马鞍山吉祥光电科技有限公司 | 一种在路灯灯杆表面制备耐腐蚀阻燃涂层的方法 |
| GB2588442A (en) * | 2019-10-24 | 2021-04-28 | Io Cyte Ltd | Antimicrobial material |
| GB201916148D0 (en) * | 2019-11-06 | 2019-12-18 | Smith & Nephew | Wound contact layer testing apparatus and method |
| US11771819B2 (en) | 2019-12-27 | 2023-10-03 | Convatec Limited | Low profile filter devices suitable for use in negative pressure wound therapy systems |
| US11331221B2 (en) | 2019-12-27 | 2022-05-17 | Convatec Limited | Negative pressure wound dressing |
| US20220241455A1 (en) * | 2021-02-04 | 2022-08-04 | Nan Liu Enterprise Co., Ltd. | Wound dressing |
| US12312162B2 (en) * | 2021-05-04 | 2025-05-27 | Munchkin, Inc. | Flexible bag assembly |
| GB202107893D0 (en) * | 2021-06-02 | 2021-07-14 | Medtrade Products Ltd | Antimicrobial wound dressing |
| EP4373539A1 (en) | 2021-07-23 | 2024-05-29 | ConvaTec Limited | A selectively configurable wound dressing |
| US20230133954A1 (en) * | 2021-11-01 | 2023-05-04 | Medtronic, Inc. | Antimicrobial foam articles |
| GB202117252D0 (en) | 2021-11-30 | 2022-01-12 | Convatec Ltd | Method of forming an Ostomy pouch |
| KR102561775B1 (ko) * | 2023-03-31 | 2023-07-28 | 우도연 | 활성탄이 함유된 열가소성 탄성중합체 |
| EP4574114A1 (de) * | 2023-12-20 | 2025-06-25 | Paul Hartmann AG | Inselverband für eine wundbehandlung mit einem acrylatklebstoff im randbereich und einem silikongel im wundkontaktierenden bereich |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101421001A (zh) * | 2006-04-11 | 2009-04-29 | 泰科保健集团有限合伙公司 | 多层创伤敷料 |
| CN101631572A (zh) * | 2007-03-01 | 2010-01-20 | 墨尼克医疗用品有限公司 | 含银泡沫结构 |
| CN102170779A (zh) * | 2008-08-28 | 2011-08-31 | 泰科保健集团有限合伙公司 | 抗微生物泡沫组合物，制品和方法 |
| WO2014074503A1 (en) * | 2012-11-06 | 2014-05-15 | Imbed Biosciences, Inc. | Methods and compositions for wound healing |
| US20140336557A1 (en) * | 2013-05-10 | 2014-11-13 | Biovation Ii, Llc | Biopolymer multi-layer multi-functional medical dressing and method of making same |
| CN105555495A (zh) * | 2013-09-26 | 2016-05-04 | 菲布罗林法国公司 | 通过将粉末转移至多孔基材中进行浸渗的装置和方法 |
| GB2537840A (en) * | 2015-04-27 | 2016-11-02 | Medtrade Products Ltd | Wound dressing |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0011471B1 (en) | 1978-11-17 | 1983-02-09 | SMITH & NEPHEW RESEARCH LIMITED | Adhesive-coated sheet material incorporating anti-bacterial substances |
| NZ199684A (en) | 1981-02-13 | 1985-03-20 | Smith & Nephew Ass | Wound dressing;wound facing layer a conformable elastomeric integral net |
| AU550098B2 (en) | 1981-05-02 | 1986-03-06 | Smith & Nephew Associated Companies Plc | Sterile dressing |
| GR79970B (enExample) | 1983-08-15 | 1984-10-31 | Personal Products Co | |
| US4559050A (en) | 1984-08-17 | 1985-12-17 | Personal Products Company | Thin, soft, absorbent product |
| US4728323A (en) | 1986-07-24 | 1988-03-01 | Minnesota Mining And Manufacturing Company | Antimicrobial wound dressings |
| US5846604A (en) | 1988-03-14 | 1998-12-08 | Nextec Applications, Inc. | Controlling the porosity and permeation of a web |
| US5869172A (en) | 1988-03-14 | 1999-02-09 | Nextec Applications, Inc. | Internally-coated porous webs with controlled positioning of modifiers therein |
| US6488670B1 (en) | 2000-10-27 | 2002-12-03 | Kimberly-Clark Worldwide, Inc. | Corrugated absorbent system for hygienic products |
| US7357949B2 (en) | 2001-12-21 | 2008-04-15 | Agion Technologies Inc. | Encapsulated inorganic antimicrobial additive for controlled release |
| CA2486057A1 (en) | 2002-05-16 | 2003-11-27 | Ferris Pharmaceuticals, Inc. | Hydrophilic foam compositions having antimicrobial properties |
| US20140107555A1 (en) * | 2002-10-23 | 2014-04-17 | Covidien Lp | Antimicrobial multilayer wound dressing |
| US20070237812A1 (en) | 2006-04-11 | 2007-10-11 | Tyco Healthcare Group | Multi-layer wound dressings |
| US6984439B2 (en) | 2002-11-12 | 2006-01-10 | Kimberly-Clark Worldwide, Inc. | Responsive film with corrugated microlayers having improved properties |
| CA2523365C (en) | 2003-04-09 | 2014-06-03 | Beiersdorf Ag | Antimicrobial materials comprising a silver-containing glass composition |
| US7790945B1 (en) * | 2004-04-05 | 2010-09-07 | Kci Licensing, Inc. | Wound dressing with absorption and suction capabilities |
| US7753894B2 (en) | 2004-04-27 | 2010-07-13 | Smith & Nephew Plc | Wound cleansing apparatus with stress |
| GB0508528D0 (en) | 2005-04-27 | 2005-06-01 | Smith & Nephew | SAI with macrostress |
| US20060127437A1 (en) | 2004-12-13 | 2006-06-15 | Misty Anderson Kennedy | Semisolid system and combination semisolid, multiparticulate system for sealing tissues and/or controlling biological fluids |
| WO2006124492A2 (en) | 2005-05-12 | 2006-11-23 | Noble Fiber Technologies, Llc | Bandage with a hydrophilic foam containing silver |
| GB0608437D0 (en) | 2006-04-28 | 2006-06-07 | Adv Med Solutions Ltd | Wound dressings |
| US20100055437A1 (en) | 2008-08-28 | 2010-03-04 | Tyco Healthcare Group Lp | Anti-microbial fibers and related articles and methods |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| US9452247B2 (en) | 2009-12-16 | 2016-09-27 | Paul Hartmann Ag | Device for negative pressure wound therapy |
| GB0922664D0 (en) | 2009-12-24 | 2010-02-10 | Adv Med Solutions Ltd | Chitosan based antimicrobial absorbent material |
| US9061095B2 (en) | 2010-04-27 | 2015-06-23 | Smith & Nephew Plc | Wound dressing and method of use |
| CN101862470A (zh) | 2010-05-28 | 2010-10-20 | 武汉锐尔生物科技有限公司 | 一种抑菌水胶体敷料及其制备方法 |
| US8901188B2 (en) | 2011-06-16 | 2014-12-02 | Kimberly-Clark Worldwide, Inc. | Antimicrobial polyurethane foam and process to make the same |
| ITBS20110095A1 (it) | 2011-06-28 | 2012-12-29 | Copromec S R L | Pistone per una macchina per la pressofusione |
| JP2013012667A (ja) | 2011-06-30 | 2013-01-17 | Sharp Corp | 太陽電池用ウエハ、太陽電池およびその製造方法 |
| EP2731564B1 (en) | 2011-07-14 | 2019-04-24 | Smith & Nephew PLC | Wound dressing and method of treatment |
| ITBO20120185A1 (it) | 2012-04-06 | 2013-10-07 | Emodial S R L | Medicazione antimicrobica, composizione antimicrobica e relativo uso |
| FR2989572B1 (fr) | 2012-04-20 | 2015-05-01 | Henkoscience | Sparadrap et son utilisation |
| ES2673223T3 (es) | 2012-05-23 | 2018-06-20 | Smith & Nephew Plc. | Aparatos para terapia de heridas por presión negativa |
| RU2015106112A (ru) | 2012-08-01 | 2016-09-20 | СМИТ ЭНД НЕФЬЮ ПиЭлСи | Раневая повязка |
| CN103074703A (zh) | 2012-12-03 | 2013-05-01 | 佛山市优特医疗科技有限公司 | 抗菌性含银纤维类伤口敷料及其制备方法 |
| EP2968013B1 (en) | 2013-03-14 | 2017-05-03 | KCI Licensing, Inc. | Absorbent dressing and method of making the same |
| JP6808323B2 (ja) | 2013-03-15 | 2021-01-06 | スミス アンド ネフュー ピーエルシーＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ Ｐｕｂｌｉｃ Ｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ | 創傷被覆シーラントおよびその使用 |
| CN203576752U (zh) | 2013-07-06 | 2014-05-07 | 圣光医用制品有限公司 | 新型海藻酸钙聚维酮碘散水刺无纺布敷料 |
| KR102483333B1 (ko) | 2013-09-13 | 2022-12-29 | 솔리제닉스, 인크. | 경구 점막염 치료에 사용하기 위한 신규한 펩티드 및 유사체 |
| US9839715B2 (en) | 2014-08-13 | 2017-12-12 | Porex Technologies Corporation | Anti-microbial foams containing polymer-stabilized silver nanoparticles |
| AU2016256204C1 (en) | 2015-04-27 | 2022-03-31 | Smith & Nephew Plc | Reduced pressure apparatuses |
| US10076594B2 (en) | 2015-05-18 | 2018-09-18 | Smith & Nephew Plc | Fluidic connector for negative pressure wound therapy |
| EP3328460B1 (en) | 2015-07-28 | 2024-11-13 | NewMedical Technology, Inc. | Systems and methods for making hydrophilic foams |
| US20170098818A1 (en) | 2015-10-02 | 2017-04-06 | The University Of Kentucky Research Foundation | Solvent-free dry powder-coating method for electrode fabrication |
| US11364150B2 (en) | 2015-12-30 | 2022-06-21 | Smith & Nephew Plc | Negative pressure wound therapy apparatus |
| DE102016125579A1 (de) | 2016-12-23 | 2018-06-28 | Paul Hartmann Ag | Wasserhaltige Hydrogelzusammensetzung, umfassend elementare Silberpartikel |
| EP3412319A1 (en) | 2017-06-09 | 2018-12-12 | Mölnlycke Health Care AB | Foam in wound treatment |
| GB201711183D0 (en) | 2017-07-12 | 2017-08-23 | Smith & Nephew | Antimicrobial or wound care materials, devices and uses |
| GB201711179D0 (en) * | 2017-07-12 | 2017-08-23 | Smith & Nephew | Wound care materials, devices and uses |
| GB201711181D0 (en) * | 2017-07-12 | 2017-08-23 | Smith & Nephew | Polymer foam material, device and use |
-
2017
- 2017-07-12 GB GBGB1711183.2A patent/GB201711183D0/en not_active Ceased
-
2018
- 2018-07-12 US US16/630,387 patent/US11730852B2/en active Active
- 2018-07-12 CN CN201880046565.XA patent/CN110891617A/zh active Pending
- 2018-07-12 AU AU2018300759A patent/AU2018300759B2/en active Active
- 2018-07-12 CA CA3069284A patent/CA3069284A1/en active Pending
- 2018-07-12 EP EP24154596.1A patent/EP4353271A1/en active Pending
- 2018-07-12 EP EP18740817.4A patent/EP3651815B1/en active Active
- 2018-07-12 WO PCT/EP2018/069015 patent/WO2019012069A1/en not_active Ceased
- 2018-07-12 JP JP2020501264A patent/JP7712764B2/ja active Active
- 2018-07-12 SG SG11201912597SA patent/SG11201912597SA/en unknown
-
2019
- 2019-12-19 ZA ZA2019/08504A patent/ZA201908504B/en unknown
-
2023
- 2023-06-27 US US18/215,019 patent/US12064523B2/en active Active
-
2024
- 2024-07-09 US US18/767,430 patent/US20240358883A1/en active Pending
- 2024-08-07 AU AU2024205594A patent/AU2024205594A1/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101421001A (zh) * | 2006-04-11 | 2009-04-29 | 泰科保健集团有限合伙公司 | 多层创伤敷料 |
| CN101631572A (zh) * | 2007-03-01 | 2010-01-20 | 墨尼克医疗用品有限公司 | 含银泡沫结构 |
| CN102170779A (zh) * | 2008-08-28 | 2011-08-31 | 泰科保健集团有限合伙公司 | 抗微生物泡沫组合物，制品和方法 |
| WO2014074503A1 (en) * | 2012-11-06 | 2014-05-15 | Imbed Biosciences, Inc. | Methods and compositions for wound healing |
| US20140336557A1 (en) * | 2013-05-10 | 2014-11-13 | Biovation Ii, Llc | Biopolymer multi-layer multi-functional medical dressing and method of making same |
| CN105555495A (zh) * | 2013-09-26 | 2016-05-04 | 菲布罗林法国公司 | 通过将粉末转移至多孔基材中进行浸渗的装置和方法 |
| GB2537840A (en) * | 2015-04-27 | 2016-11-02 | Medtrade Products Ltd | Wound dressing |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111346255A (zh) * | 2020-04-21 | 2020-06-30 | 四川大学 | 兼具抗菌和带菌警示功能的伤口敷料及其制备方法 |
| CN111346255B (zh) * | 2020-04-21 | 2022-04-19 | 四川大学 | 兼具抗菌和带菌警示功能的伤口敷料及其制备方法 |
| CN115463270A (zh) * | 2022-09-13 | 2022-12-13 | 湖北世丰新材料有限公司 | 一种负压引流医用海绵及其制备方法 |
| CN115990284A (zh) * | 2023-01-06 | 2023-04-21 | 杭州沸创生命科技股份有限公司 | 一种止血纱布涂布用的浆料及利用其制备的止血纱布 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3651815A1 (en) | 2020-05-20 |
| ZA201908504B (en) | 2022-05-25 |
| US12064523B2 (en) | 2024-08-20 |
| SG11201912597SA (en) | 2020-01-30 |
| AU2024205594A1 (en) | 2024-08-29 |
| GB201711183D0 (en) | 2017-08-23 |
| EP3651815B1 (en) | 2024-03-27 |
| EP4353271A1 (en) | 2024-04-17 |
| US20210085819A1 (en) | 2021-03-25 |
| AU2018300759A1 (en) | 2020-01-16 |
| CA3069284A1 (en) | 2019-01-17 |
| US11730852B2 (en) | 2023-08-22 |
| JP7712764B2 (ja) | 2025-07-24 |
| WO2019012069A1 (en) | 2019-01-17 |
| JP2020526331A (ja) | 2020-08-31 |
| US20240358883A1 (en) | 2024-10-31 |
| AU2018300759B2 (en) | 2024-06-20 |
| US20230414824A1 (en) | 2023-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12064523B2 (en) | Antimicrobial or wound care materials, devices and uses | |
| US20250025595A1 (en) | Wound care materials, devices and uses | |
| US11730854B2 (en) | Polymer foam material, device and use | |
| JP7204685B2 (ja) | 陰圧治療での肉芽形成を促進し浸軟を低減させる複合ドレッシング | |
| JP6867337B2 (ja) | 創傷被覆材 | |
| JP7000419B2 (ja) | 加圧下で使用する医療システムおよびドレッシング | |
| AU2014342903B2 (en) | Dressing with differentially sized perforations | |
| JP6320930B2 (ja) | 剥離可能な医療用ドレープ | |
| AU2009331911B2 (en) | Wound dressing | |
| JP7044705B2 (ja) | 負圧創傷治療装置 | |
| CN103857365B (zh) | 伤口敷料和治疗方法 | |
| JP2022105190A (ja) | 創傷被覆材 | |
| JP2014512919A (ja) | 創傷ケア用品 | |
| KR20230016628A (ko) | 음압 상처 치료(npwt) 드레싱 | |
| US20140228786A1 (en) | Absorbent body for the therapeutic treatment of a wound by means of negative pressure | |
| JP2023527751A (ja) | 陰圧創傷治療（ｎｐｗｔ）被覆材 | |
| US20240024531A1 (en) | Polymer foam material, device & use | |
| EP1653899B1 (en) | Absorbent sheet with leakage barriers for use in wound dressing | |
| CN120435271A (zh) | 伤口敷料 | |
| CN120344219A (zh) | 伤口敷料 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |