CN110832077B - 用于抑制α-ENaC表达的RNAi剂及使用方法 - Google Patents

用于抑制α-ENaC表达的RNAi剂及使用方法 Download PDF

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CN110832077B
CN110832077B CN201880045293.1A CN201880045293A CN110832077B CN 110832077 B CN110832077 B CN 110832077B CN 201880045293 A CN201880045293 A CN 201880045293A CN 110832077 B CN110832077 B CN 110832077B
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rnai agent
enac
nucleotides
seq
sense strand
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CN110832077A (zh
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李珍
朱锐
裴涛
A.尼古拉斯
E.W.布什
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Arrowhead Pharmaceuticals Inc
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US201762529132P 2017-07-06 2017-07-06
US62/529132 2017-07-06
US201862631683P 2018-02-17 2018-02-17
US62/631683 2018-02-17
US201862679549P 2018-06-01 2018-06-01
US62/679549 2018-06-01
PCT/US2018/040874 WO2019010274A1 (en) 2017-07-06 2018-07-05 RNAI AGENTS OF INHIBITION OF ALPHA-ENAC GENE EXPRESSION AND METHODS OF USE

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TW202130809A (zh) * 2019-10-29 2021-08-16 美商愛羅海德製藥公司 用於抑制β-ENaC表現之RNAi藥劑、其組合物及使用方法
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CA3061752A1 (en) 2019-01-10
UY37800A (es) 2019-01-02
CN119662650A (zh) 2025-03-21
IL271843A (en) 2020-02-27
JOP20190263A1 (ar) 2019-11-12
JP2020526192A (ja) 2020-08-31
US20220090077A1 (en) 2022-03-24
EP3649240A4 (en) 2021-07-07
JP2025185070A (ja) 2025-12-18
WO2019010274A1 (en) 2019-01-10
US20190010494A1 (en) 2019-01-10
US10590416B2 (en) 2020-03-17
US20200299691A1 (en) 2020-09-24
JP2023158192A (ja) 2023-10-26
CL2020000019A1 (es) 2020-06-12
CR20190572A (es) 2020-05-23
MX2019014800A (es) 2020-02-10
CN110832077A (zh) 2020-02-21
AU2018297262A1 (en) 2020-02-27
PH12019502660A1 (en) 2020-06-08
ZA202100643B (en) 2023-03-29
TN2019000308A1 (en) 2021-05-07
BR112019023650A2 (pt) 2020-06-02
ECSP20000655A (es) 2020-05-29
CO2019014671A2 (es) 2020-01-17
TW201919654A (zh) 2019-06-01
KR20200024793A (ko) 2020-03-09
EP3649240A1 (en) 2020-05-13
US11214802B2 (en) 2022-01-04
PE20200746A1 (es) 2020-07-24

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