CN110799646B - 变态反应的抗原及其表位 - Google Patents

变态反应的抗原及其表位 Download PDF

Info

Publication number
CN110799646B
CN110799646B CN201880043071.6A CN201880043071A CN110799646B CN 110799646 B CN110799646 B CN 110799646B CN 201880043071 A CN201880043071 A CN 201880043071A CN 110799646 B CN110799646 B CN 110799646B
Authority
CN
China
Prior art keywords
amino acid
seq
glu
antigen
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201880043071.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN110799646A (zh
Inventor
松永佳世子
矢上晶子
中村政志
下條尚志
佐藤奈由
青木祐治
酒井智美
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujita Health University
Original Assignee
Fujita Health University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujita Health University filed Critical Fujita Health University
Priority to CN202411414860.XA priority Critical patent/CN119086940A/zh
Publication of CN110799646A publication Critical patent/CN110799646A/zh
Application granted granted Critical
Publication of CN110799646B publication Critical patent/CN110799646B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43508—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from crustaceans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Insects & Arthropods (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
CN201880043071.6A 2017-04-28 2018-05-01 变态反应的抗原及其表位 Active CN110799646B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202411414860.XA CN119086940A (zh) 2017-04-28 2018-05-01 变态反应的抗原及其表位

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2017-090438 2017-04-28
JP2017090438 2017-04-28
PCT/JP2018/017472 WO2018199341A1 (ja) 2017-04-28 2018-05-01 アレルギーの抗原およびそのエピトープ

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202411414860.XA Division CN119086940A (zh) 2017-04-28 2018-05-01 变态反应的抗原及其表位

Publications (2)

Publication Number Publication Date
CN110799646A CN110799646A (zh) 2020-02-14
CN110799646B true CN110799646B (zh) 2024-10-22

Family

ID=63919715

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201880043071.6A Active CN110799646B (zh) 2017-04-28 2018-05-01 变态反应的抗原及其表位
CN202411414860.XA Pending CN119086940A (zh) 2017-04-28 2018-05-01 变态反应的抗原及其表位

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202411414860.XA Pending CN119086940A (zh) 2017-04-28 2018-05-01 变态反应的抗原及其表位

Country Status (6)

Country Link
US (2) US20200188510A1 (https=)
EP (1) EP3617312B1 (https=)
JP (4) JP7184259B2 (https=)
KR (2) KR20260017488A (https=)
CN (2) CN110799646B (https=)
WO (1) WO2018199341A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4004021B1 (en) 2019-07-22 2025-09-03 Oneskin, Inc. Polypeptides having anti-senescent effects and uses thereof
US20230251269A1 (en) * 2020-07-15 2023-08-10 The Johns Hopkins University Comprehensive analysis of anti-allergen antibodies using phage display
CN115974994B (zh) * 2022-10-08 2025-09-05 汕头大学 一种来源于凡纳对虾血蓝蛋白的降低血氨毒性及浓度的降解片段PvHMCs27及其应用
CN115963273B (zh) * 2022-10-09 2024-04-12 中国海洋大学 一种三疣梭子蟹nSCP或rSCP的应用与试剂盒
EP4635973A1 (en) * 2022-12-16 2025-10-22 Toagosei Co., Ltd. Synthetic peptide and construct
KR102803104B1 (ko) * 2023-05-15 2025-05-09 아주대학교산학협력단 새우에 대한 아나필락시스 진단용 바이오마커 조성물 및 이의 용도

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015153151A1 (en) * 2014-04-03 2015-10-08 Genisphere, Llc Peptides, reagents and methods for detecting food allergy
WO2016190376A1 (ja) * 2015-05-25 2016-12-01 ホーユー株式会社 ウズラの卵アレルギーの抗原

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5449669A (en) * 1993-11-10 1995-09-12 The United States Of America As Represented By The Department Of Health And Human Services IgE-binding epitopes of a major heat-stable crustacean allergen derived from shrimp
JP4578709B2 (ja) 2001-03-28 2010-11-10 三菱化学メディエンス株式会社 複数項目同時分析可能なイムノクロマトグラフ法及びイムノクロマトグラフ用ストリップ
JP2006508163A (ja) * 2002-11-27 2006-03-09 アジェンシス， インコーポレイテッド 癌の処置および検出において有用な２４ｐ４ｃ１２と称される、核酸および対応タンパク質
US20060210590A1 (en) * 2005-02-03 2006-09-21 Alk-Abello A/S Minor allergen control to increase safety of immunotherapy
JP4444306B2 (ja) * 2007-04-05 2010-03-31 博 宮澤 エビアレルゲン及び抗エビアレルゲン抗体並びにその利用
WO2011014866A1 (en) * 2009-07-31 2011-02-03 Mount Sinai School Of Medicine Of New York University Materials and methods for diagnosing and treating shellfish allergy
JP5513802B2 (ja) 2009-08-04 2014-06-04 ホーユー株式会社 等電点電気泳動用ゲル及び等電点電気泳動方法
JP5433341B2 (ja) 2009-08-04 2014-03-05 ホーユー株式会社 等電点電気泳動方法及び粗雑物除去の判定方法
JP5190423B2 (ja) 2009-08-04 2013-04-24 ホーユー株式会社 ２次元電気泳動方法
JP5475358B2 (ja) 2009-08-04 2014-04-16 ホーユー株式会社 ２次元電気泳動方法
MX2014009285A (es) * 2012-02-07 2015-02-04 Jolla Inst Allergy Immunolog Alergenos del fleo de los prados y metodos y usos para la modulacion de respuesta inmune.
US11505581B2 (en) * 2015-05-14 2022-11-22 La Jolla Institute For Allergy And Immunology Antigens and T cell epitopes from cockroach and methods of making and using same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015153151A1 (en) * 2014-04-03 2015-10-08 Genisphere, Llc Peptides, reagents and methods for detecting food allergy
WO2016190376A1 (ja) * 2015-05-25 2016-12-01 ホーユー株式会社 ウズラの卵アレルギーの抗原

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Cloning, expression, and localization of two types of fast skeletal myosin heavy chain genes from black tiger and Pacific white shrimps;Koyama H等;《J Exp Zool A Ecol Genet Physiol.》;第317卷(第317期);608-621 *
Identification of a novel allergen from muscle and various organs in banana shrimp (Fenneropenaeus merguiensis);Khanaruksombat S等;《Ann Allergy Asthma Immunol》;第113卷(第113期);301-306 *

Also Published As

Publication number Publication date
JP7184259B2 (ja) 2022-12-06
CN110799646A (zh) 2020-02-14
CN119086940A (zh) 2024-12-06
EP3617312A1 (en) 2020-03-04
KR20260017488A (ko) 2026-02-05
EP3617312C0 (en) 2026-02-18
JPWO2018199341A1 (ja) 2020-03-26
US20200188510A1 (en) 2020-06-18
KR20200002888A (ko) 2020-01-08
EP3617312A4 (en) 2021-04-07
JP2023027061A (ja) 2023-03-01
WO2018199341A1 (ja) 2018-11-01
JP2024026181A (ja) 2024-02-28
JP2025118770A (ja) 2025-08-13
US20240108719A1 (en) 2024-04-04
EP3617312A8 (en) 2020-04-29
EP3617312B1 (en) 2026-02-18

Similar Documents

Publication Publication Date Title
CN110799646B (zh) 变态反应的抗原及其表位
US20230295251A1 (en) Allergy antigen and epitope for same
US20240393292A1 (en) Allergy antigen and epitope thereof
CN111051336B (zh) 变态反应的抗原及其表位
JP2025093999A (ja) 牛乳アレルギーの新規抗原
KR20210095986A (ko) 알레르기 항원 및 그 에피토프

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant