CN110742852A - Composition for multi-effect repair of sensitive skin and preparation method and application thereof - Google Patents

Composition for multi-effect repair of sensitive skin and preparation method and application thereof Download PDF

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CN110742852A
CN110742852A CN201911120676.3A CN201911120676A CN110742852A CN 110742852 A CN110742852 A CN 110742852A CN 201911120676 A CN201911120676 A CN 201911120676A CN 110742852 A CN110742852 A CN 110742852A
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phase
percent
composition
mixture
skin
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蒋英华
袁清标
高戎戎
劳敏翔
戴晶
杨暶
袁博
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Shanghai Saier Biotechnology Co Ltd
Shanghai Biohope Chemical Co Ltd
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Shanghai Saier Biotechnology Co Ltd
Shanghai Biohope Chemical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a composition for multi-effect repair of sensitive skin, a preparation method and application thereof. The ceramide comprises any one or a mixture of more of ceramide NP, ceramide AP and ceramide EOP. The composition further comprises hydrogenated polydecene, cetearyl alcohol, tridecyl alcohol trimellitate, polydimethylsiloxane, glycerin, tetrasodium EDTA, phytosphingosine, carbomer, xanthan gum, methylparaben, triethanolamine, etc. The invention also provides a preparation method and application of the composition. The composition is a composition of a skin barrier suitable for multi-effect repair of all skin types, aims at the skin barrier damage and sensitive skin groups caused by different reasons, and can delay senility and resist dry wrinkles, dark pox and the like.

Description

Composition for multi-effect repair of sensitive skin and preparation method and application thereof
Technical Field
The invention relates to a composition for skin care cosmetics, a preparation method and application thereof, in particular to a composition for multi-effect repair of sensitive skin, a preparation method and application thereof.
Background
The skin is our collective protective barrier, being the first line of defense we are against foreign "aggressors", and it comprises the epidermis and the dermis, where the dermis provides the elastic support. The epidermis provides protection and is an important component of the "skin barrier". The epidermal barrier refers to a natural protective membrane of the skin, including the sebaceous membrane: weakly acidic, water-oil ratio 7: 3; horny layer: when the skin barrier is damaged and the stratum corneum can not prevent water loss, a large amount of water in the skin can be lost, pollution and microorganisms can enter hair follicles, sebaceous glands in the hair follicles can be stimulated, excessive sebum secretion can be caused, various skin inflammations can be caused, various skin diseases and skin sensitivity can be caused, even the skin aging is accelerated, and except repairing the barrier, more moisturizing components and nutrient components are useless. For people with sensitive skin, the repair of the skin barrier is particularly important and is a great technical difficulty, the skin barrier of the sensitive skin is very fragile, the skin sensitivity can be accelerated due to improper use of skin care products, the range of the skin care products which can be used by skin sensitive people is suddenly reduced, and a vicious circle is formed.
Disclosure of Invention
The invention aims to provide a skin barrier composition suitable for multi-effect repair of all skin types, a preparation method thereof and application thereof in skin care products, which can solve the existing problems, aim at the skin barrier damage and sensitive skin groups caused by different reasons, delay aging and resist dry wrinkles, dark pox and the like.
In order to achieve the above objects, the present invention provides a composition for pleiotropic repair of sensitive skin, wherein the composition comprises: ceramide, artemia salina extract, fullerene and sodium tocopheryl phosphate.
The composition for pleiotropic repair of sensitive skin comprises one or a mixture of more of ceramide NP, ceramide AP and ceramide EOP.
The composition for pleiotropic repair of sensitive skin as described above, wherein said composition further comprises: hydrogenated polydecene, cetostearyl alcohol, tridecyl alcohol trimellitate, polydimethylsiloxane, glycerin, tetrasodium EDTA, vegetable sphingosine alcohol, carbomer, xanthan gum, methylparaben, triethanolamine, and water.
The composition for pleiotropic repair of sensitive skin as described above, wherein said composition further comprises: any one or mixture of caprylic or capric triglyceride; any one or a mixture of phenoxyethanol and caprylyl glycol; any one or mixture of acrylic acid and esters or C10-30 alkanol acrylate cross-linked polymers; any one or a mixture of more of polyacrylate-13, polyisobutylene and polysorbate-20.
The composition for pleiotropic repair of sensitive skin as described above, wherein said composition further comprises: any one or a mixture of more of glycerol, glycerol acrylate, acrylic acid copolymer, propylene glycol and PVM/MA copolymer.
The composition for multi-effect repair of sensitive skin comprises the following components in percentage by mass: 0.1 to 10 percent of ceramide, 0.05 to 5 percent of artemia salina extract, 0.05 to 5 percent of fullerene, 0.05 to 0.5 percent of sodium tocopheryl phosphate, 3 percent of hydrogenated polydecene, 3 percent of cetearyl alcohol, 2 percent of tridecyl trimellitate, 1.5 percent of polydimethylsiloxane, 5 percent of glycerol, 0.05 percent of tetrasodium EDTA, 0.05 to 5 percent of plant sphingosine, 0.2 percent of carbomer, 0.1 percent of xanthan gum, 0.2 percent of methyl hydroxybenzoate, 0.45 percent of triethanolamine, 5 percent of any one or mixture of caprylic acid or capric triglyceride, 0.4 percent of any one or mixture of phenoxyethanol or capryl glycol, 0.4 percent of any one or mixture of acrylic acid and esters or C10 to 30 alkanol acrylate cross-linked polymers, 1.1 percent of any one or mixture of more of polyacrylate-13, polyisobutylene and polysorbate-20, 3% of any one or a mixture of more of glycerol, glycerol acrylate, acrylic acid copolymer, propylene glycol and PVM/MA copolymer, and the balance of water.
The invention also provides a preparation method of the composition for multi-effect repair of sensitive skin, wherein the method comprises the following steps: step 1, weighing raw materials in proportion, and dividing the raw materials into an A phase, a B phase, a C phase and a D phase; phase A comprises hydrogenated polydecene, cetearyl alcohol, tridecyl alcohol trimellitate, polydimethylsiloxane, any one or mixture of caprylic acid triglyceride and capric acid triglyceride, any one or mixture of acrylic acid and esters or C10-30 alkanol acrylate cross-linked polymer, any one or mixture of polyacrylate-13, polyisobutylene and polysorbate-20, and deionized water; phase B comprises one or more of glycerol, sodium tocopheryl phosphate, ceramide, tetrasodium EDTA, phytosphingosine, carbomer, xanthan gum, methyl hydroxybenzoate, glycerol acrylate, acrylic acid copolymer, propylene glycol, and PVM/MA copolymer; phase C contains triethanolamine; phase D comprises one or more of Haliotis extract, fullerene, phenoxyethanol or octyl glycol; step 2, respectively heating the components of the phase A and the phase B to 75 ℃, and respectively and uniformly mixing the components to form the phase A and the phase B; step 3, adding the phase B into the phase A under the stirring condition, homogenizing, adding the phase C, and homogenizing; and 4, slowly stirring and cooling to 40 ℃, sequentially adding the D-phase components, and fully and uniformly stirring.
In the step 3, the phase B is added into the phase A under the stirring condition, the homogenization is carried out for 2-3min at the rotating speed of 8000 revolutions per minute, then the phase C is added, and the homogenization is carried out for 2-3min at the rotating speed of 8000 revolutions per minute.
The invention also provides the use of the composition prepared by the method, wherein the composition is used for preparing a skin care product.
The composition is used in a skin care product, so that the composition has the function of repairing a sensitive skin barrier in a multiple-effect manner.
The composition for multi-effect repair of sensitive skin, the preparation method and the application provided by the invention have the following advantages:
the invention aims at the crowds with damaged skin barriers and sensitive skin caused by different reasons, and can delay senility and resist wrinkles, dark spots, acnes and the like. The repair barrier composition combines ceramides, fullerene, plankton extracts and tocopherol which have various conformations and are homologous with a human body for the first time, is suitable for people with damaged skin barriers of all skin types, improves the skin types, locks skin moisture, resists sensitivity and delays skin aging while repairing and reinforcing the skin barriers.
Detailed Description
The following further describes embodiments of the present invention.
The invention provides a composition for pleiotropic repair of sensitive skin, which comprises: ceramide, artemia salina extract, fullerene and sodium tocopheryl phosphate.
The ceramide comprises one or more of ceramide NP, ceramide AP and ceramide EOP (namely ceramide NP/ceramide AP/ceramide EOP).
The composition further comprises: hydrogenated polydecene, cetostearyl alcohol, tridecyl alcohol trimellitate, polydimethylsiloxane, glycerin, tetrasodium EDTA, vegetable sphingosine alcohol, Carbomer (polymer of acrylic acid bonded allyl sucrose or pentaerythritol allyl ether), collagen, methylparaben, triethanolamine, and water.
The composition further comprises: either caprylic or capric triglyceride or mixtures thereof (i.e., caprylic/capric triglyceride); phenoxyethanol or caprylyl glycol or a mixture thereof (i.e., phenoxyethanol/caprylyl glycol); any one or mixture of acrylic acid and esters or C10-30 alkanol acrylate cross-linked polymers (i.e. acrylic acid and esters/C10-30 alkanol acrylate cross-linked polymers); one or more of polyacrylate-13, polyisobutylene and polysorbate-20 (i.e. polyacrylate-13/polyisobutylene/polysorbate-20).
The composition further comprises: glycerin, glycerin acrylate, acrylic acid copolymer, propylene glycol, and PVM/MA (Polyvinylmethyl Ether/Maleic Anhydride) copolymer (i.e. glycerin/glycerin acrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer).
Preferably, the composition comprises, in mass percent: 0.1 to 10 percent of ceramide, 0.05 to 5 percent of artemia salina extract, 0.05 to 5 percent of fullerene, 0.05 to 0.5 percent of sodium tocopheryl phosphate, 3 percent of hydrogenated polydecene, 3 percent of cetearyl alcohol, 2 percent of tridecyl trimellitate, 1.5 percent of polydimethylsiloxane, 5 percent of glycerol, 0.05 percent of tetrasodium EDTA, 0.05 to 5 percent of plant sphingosine, 0.2 percent of carbomer, 0.1 percent of xanthan gum, 0.2 percent of methyl hydroxybenzoate, 0.45 percent of triethanolamine, 5 percent of any one or mixture of caprylic acid or capric triglyceride, 0.4 percent of any one or mixture of phenoxyethanol or capryl glycol, 0.4 percent of any one or mixture of acrylic acid and esters or C10 to 30 alkanol acrylate cross-linked polymers, 1.1 percent of any one or mixture of more of polyacrylate-13, polyisobutylene and polysorbate-20, 3% of any one or a mixture of more of glycerol, glycerol acrylate, acrylic acid copolymer, propylene glycol and PVM/MA copolymer, and the balance of water.
The ceramide is a phospholipid taking ceramide as a skeleton, mainly comprises ceramide phosphorylcholine and ceramide phosphorylethanolamine, is a main component of a cell membrane, 40-50% of sebum in a horny layer is composed of ceramide, the ceramide is a main part of an intercellular matrix and plays an important role in keeping moisture balance of the horny layer, and various ceramide compounds and a natural protective barrier of the skin act together to play a synergistic role, so that the water loss of the skin can be prevented, the external influence can be resisted, and the mixture of the natural lipid barrier of the skin is simulated.
Artemia Extract (Artemia Extract) is a nucleotide mixture derived from extremophilic plankton under a pressure environment, and mainly contains Diguanosine Tetraphosphate (guanosine Tetraphosphate, GP 4G). The extract has multiple protection and compression-resistant targets, can effectively resist damage of proteins, RNA, mitochondria and the like caused by UV, infrared, overheating, supercooling and other pressures, can also promote the activity of hair follicle cells and promote hair growth, and simultaneously, the effective component GP4G in the extract can be converted into ATP when needed, participates in tricarboxylic acid cycle to supply energy to the mitochondria, and can be used as natural kinetic energy of skin.
The fullerene has a perfectly symmetrical carbon structure C60, the largest molecule in the space, the world authority determines that the fullerene has the strongest capacity of stably capturing free radicals, and the Nobel prize background can effectively absorb the free radicals generated by laser induction so as to inhibit pigmentation particularly in the process of repairing after laser skin beautifying.
The sodium tocopheryl phosphate is a water-soluble vitamin E derivative in the first world of the cosmetic industry, efficiently permeates into the skin and is converted into tocopherol, has excellent anti-inflammatory and antioxidant effects, can promote the skin to synthesize ceramide, maintain the skin barrier, increase the antioxidant effect of skin cells, maintain and promote the cell function through scientific verification, has a certain anti-aging effect, can improve lipid metabolism, balance oil and achieve high moisturizing effect.
The invention also provides a preparation method of the composition, which comprises the following steps: step 1, weighing raw materials in proportion, and dividing the raw materials into an A phase, a B phase, a C phase and a D phase; phase A comprises hydrogenated polydecene, cetearyl alcohol, tridecyl alcohol trimellitate, polydimethylsiloxane, any one or mixture of caprylic acid triglyceride and capric acid triglyceride, any one or mixture of acrylic acid and esters or C10-30 alkanol acrylate cross-linked polymer, any one or mixture of polyacrylate-13, polyisobutylene and polysorbate-20, and deionized water; phase B comprises one or more of glycerol, sodium tocopheryl phosphate, ceramide, tetrasodium EDTA, phytosphingosine, carbomer, xanthan gum, methyl hydroxybenzoate, glycerol acrylate, acrylic acid copolymer, propylene glycol, and PVM/MA copolymer; phase C contains triethanolamine; phase D comprises one or more of Haliotis extract, fullerene, phenoxyethanol or octyl glycol; step 2, respectively heating the components of the phase A and the phase B to 75 ℃, and respectively and uniformly mixing the components to form the phase A and the phase B; step 3, adding the phase B into the phase A under the stirring condition, homogenizing, adding the phase C, and homogenizing; and 4, slowly stirring and cooling to 40 ℃, sequentially adding the D-phase components, and fully and uniformly stirring.
Preferably, in step 3, adding phase B into phase A under stirring, homogenizing at 8000 rpm for 2-3min, adding phase C, and homogenizing at 8000 rpm for 2-3 min.
The invention also provides the use of the composition prepared by the method, and the composition is used for preparing skin care products. The composition is used in skin care products to provide multiple effects in repairing sensitive skin barrier.
The following will further describe the composition for multi-effect repair of sensitive skin, the preparation method and the use thereof provided by the invention with reference to the examples.
Examples 1 to 3
In each example, a composition was prepared according to the raw material composition ratios shown in table 1 below. All the raw materials respectively accord with the corresponding national standards.
Table 1, composition formulation table (in mass percent).
The invention also provides a preparation method of the composition of each embodiment, and application of the prepared composition of each embodiment.
The method comprises the following steps: step 1, weighing raw materials in proportion, and dividing the raw materials into an A phase, a B phase, a C phase and a D phase; phase A comprises hydrogenated polydecene, cetearyl alcohol, tridecyl alcohol trimellitate, polydimethylsiloxane, any one or mixture of caprylic acid triglyceride and capric acid triglyceride, any one or mixture of acrylic acid and esters or C10-30 alkanol acrylate cross-linked polymer, any one or mixture of polyacrylate-13, polyisobutylene and polysorbate-20, and deionized water; phase B comprises one or more of glycerol, sodium tocopheryl phosphate, ceramide, tetrasodium EDTA, phytosphingosine, carbomer, xanthan gum, methyl hydroxybenzoate, glycerol acrylate, acrylic acid copolymer, propylene glycol, and PVM/MA copolymer; phase C contains triethanolamine; phase D comprises one or more of Haliotis extract, fullerene, phenoxyethanol or octyl glycol; step 2, respectively heating the components of the phase A and the phase B to 75 ℃, and respectively and uniformly mixing the components to form the phase A and the phase B; step 3, adding the phase B into the phase A under the stirring condition, homogenizing at the rotating speed of 8000 revolutions per minute for 2-3min, adding the phase C, and homogenizing at the rotating speed of 8000 revolutions per minute for 2-3 min; and 4, slowly stirring and cooling to 40 ℃, sequentially adding the D-phase components, and fully and uniformly stirring.
The invention also provides the use of the composition prepared by the method, and the composition is used for preparing skin care products. The composition is used in skin care products to provide multiple effects in repairing sensitive skin barrier.
The compositions of the various embodiments of the present invention were tested and evaluated in the following manner.
Grouping experiments: the method comprises the steps of randomly screening 20 crowds with different ages and sexes and sensitive skin by dividing the crowds into a placebo group and an experimental group, wherein the experimental group is smeared with the composition of the invention, and the control group is smeared with common moisturizing liquid as a placebo. The left and right faces of the same test person are respectively a control area and a test area, and the test person evaluates the effect of the test person when the test person is used for one month, two months and three months.
Evaluation criteria:
and (3) curing: the symptoms of desquamation, redness, itching, stabbing pain, acne and color depth of the skin completely disappear.
The method has the following advantages: skin desquamation, redness, itching, pricking pain, acne, and symptoms substantially disappeared with a few pale red pocks.
And (4) invalidation: symptoms of desquamation, redness, itching, stabbing pain, acne and deep color of the skin are not obviously improved.
Side effects: symptoms of desquamation, redness, itching, pricking pain, acne and color depth of skin are aggravated.
Effective rate (cure number + effective number)/observation number × 100%.
The results of the experiment are shown in table 2.
Table 2, statistical table of experimental results (number of examples).
Figure BDA0002275376970000071
Figure BDA0002275376970000081
As can be seen from the results, after 3 months of use, the effective rate of each group was compared, the effective rate of the placebo group was 10%, and the effective rate of the comparative experiment group was 90%, and the results showed that, compared to comparative example 1: 9, on the premise of keeping the moisture retention of the skin to be equivalent, after the composition disclosed by the invention is used, the damaged barrier of the skin can be quickly and effectively improved and repaired, meanwhile, discomfort does not occur after long-time use, and the composition has an ultra-strong effect of repairing the epidermal barrier.
The main components of the composition comprise ceramide, artemia extract, fullerene, sodium tocopheryl phosphate and the like, the composition is a composition of a skin barrier suitable for multi-effect repair of all skin types, and the composition can be used for people with damaged skin barriers and sensitive skin caused by different reasons, and can delay senility and resist wrinkle, dark and acne and the like.
While the present invention has been described in detail with reference to the preferred embodiments, it should be understood that the above description should not be taken as limiting the invention. Various modifications and alterations to this invention will become apparent to those skilled in the art upon reading the foregoing description. Accordingly, the scope of the invention should be determined from the following claims.

Claims (10)

1. A composition for pleiotropic repair of sensitive skin, comprising:
ceramide, artemia salina extract, fullerene and sodium tocopheryl phosphate.
2. The composition for pleiotropic repair of sensitive skin of claim 1, wherein the ceramide comprises any one or a mixture of ceramide NP, ceramide AP, ceramide EOP.
3. The composition for pleiotropic repair of sensitive skin of claim 1, further comprising:
hydrogenated polydecene, cetostearyl alcohol, tridecyl alcohol trimellitate, polydimethylsiloxane, glycerin, tetrasodium EDTA, vegetable sphingosine alcohol, carbomer, xanthan gum, methylparaben, triethanolamine, and water.
4. The composition for pleiotropic repair of sensitive skin of claim 3, further comprising: any one or mixture of caprylic or capric triglyceride; any one or a mixture of phenoxyethanol and caprylyl glycol; any one or mixture of acrylic acid and esters or C10-30 alkanol acrylate cross-linked polymers; any one or a mixture of more of polyacrylate-13, polyisobutylene and polysorbate-20.
5. The composition for pleiotropic repair of sensitive skin of claim 4, further comprising: any one or a mixture of more of glycerol, glycerol acrylate, acrylic acid copolymer, propylene glycol and PVM/MA copolymer.
6. The composition for pleiotropic repair of sensitive skin of claim 5, comprising, in mass percent:
0.1 to 10 percent of ceramide, 0.05 to 5 percent of artemia salina extract, 0.05 to 5 percent of fullerene, 0.05 to 0.5 percent of sodium tocopheryl phosphate, 3 percent of hydrogenated polydecene, 3 percent of cetearyl alcohol, 2 percent of tridecyl trimellitate, 1.5 percent of polydimethylsiloxane, 5 percent of glycerol, 0.05 percent of tetrasodium EDTA, 0.05 to 5 percent of plant sphingosine, 0.2 percent of carbomer, 0.1 percent of xanthan gum, 0.2 percent of methyl hydroxybenzoate, 0.45 percent of triethanolamine, 5 percent of any one or mixture of caprylic acid or capric triglyceride, 0.4 percent of any one or mixture of phenoxyethanol or capryl glycol, 0.4 percent of any one or mixture of acrylic acid and esters or C10 to 30 alkanol acrylate cross-linked polymers, 1.1 percent of any one or mixture of more of polyacrylate-13, polyisobutylene and polysorbate-20, 3% of any one or a mixture of more of glycerol, glycerol acrylate, acrylic acid copolymer, propylene glycol and PVM/MA copolymer, and the balance of water.
7. A method of preparing a composition for pleiotropic skin rejuvenation as claimed in any one of claims 1 to 6, comprising:
step 1, weighing raw materials in proportion, and dividing the raw materials into an A phase, a B phase, a C phase and a D phase;
phase A comprises hydrogenated polydecene, cetearyl alcohol, tridecyl alcohol trimellitate, polydimethylsiloxane, any one or mixture of caprylic acid triglyceride and capric acid triglyceride, any one or mixture of acrylic acid and esters or C10-30 alkanol acrylate cross-linked polymer, any one or mixture of polyacrylate-13, polyisobutylene and polysorbate-20, and deionized water;
phase B comprises one or more of glycerol, sodium tocopheryl phosphate, ceramide, tetrasodium EDTA, phytosphingosine, carbomer, xanthan gum, methyl hydroxybenzoate, glycerol acrylate, acrylic acid copolymer, propylene glycol, and PVM/MA copolymer;
phase C contains triethanolamine;
phase D comprises one or more of Haliotis extract, fullerene, phenoxyethanol or octyl glycol;
step 2, respectively heating the components of the phase A and the phase B to 75 ℃, and respectively and uniformly mixing the components to form the phase A and the phase B;
step 3, adding the phase B into the phase A under the stirring condition, homogenizing, adding the phase C, and homogenizing;
and 4, stirring and cooling to 40 ℃, sequentially adding the D-phase components, and uniformly stirring.
8. The method of claim 7, wherein in step 3, phase B is added to phase A under stirring, followed by homogenization at 8000 rpm for 2-3min, then phase C is added, followed by homogenization at 8000 rpm for 2-3 min.
9. Use of a composition prepared according to the method of claim 7 for the preparation of a skin care product.
10. Use of a composition according to claim 9, wherein the composition is used in a skin care product to provide pleiotropic barrier repair of sensitive skin.
CN201911120676.3A 2019-11-15 2019-11-15 Composition for multi-effect repair of sensitive skin and preparation method and application thereof Pending CN110742852A (en)

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CN112972360A (en) * 2021-03-03 2021-06-18 上海好肌茵生物科技有限公司 Sensitive repairing composition and preparation method and application thereof
CN113476394A (en) * 2021-08-04 2021-10-08 上海梦希生物科技有限公司 Composition for effectively regulating dryness and desquamation of skin and preparation method and application thereof
CN113476391A (en) * 2021-07-28 2021-10-08 上海梦希生物科技有限公司 Composition for rapidly repairing sunburn and preparation method and application thereof
CN113616561A (en) * 2021-09-27 2021-11-09 上海新高姿化妆品有限公司 Composition with moisturizing and repairing effects and cosmetic
CN113662902A (en) * 2021-09-26 2021-11-19 沃淄(上海)生物科技有限公司 Composition for rapidly repairing skin injury caused by hypoxia and preparation method and application thereof
CN114053201A (en) * 2021-11-03 2022-02-18 沃淄(上海)生物科技有限公司 Composition for strongly repairing damaged skin lipid membrane and preparation method and application thereof
CN115364006A (en) * 2021-12-29 2022-11-22 皓雨(广州)化妆品制造有限公司 Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product
CN115844757A (en) * 2022-11-21 2023-03-28 宁波伯通伟达生物医药有限公司 Ceramide face cream and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106420560A (en) * 2016-10-19 2017-02-22 广东丸美生物技术股份有限公司 Skincare matrix with functions of moisturizing and relieving sensitive skin as well as preparation and application thereof
CN108852869A (en) * 2018-09-04 2018-11-23 广东科玮生物技术股份有限公司 The skin care compositions of anti-blue light contamination and its application
CN110101614A (en) * 2019-04-18 2019-08-09 广州科恩生物技术有限公司 A kind of fullerene remediation composition and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106420560A (en) * 2016-10-19 2017-02-22 广东丸美生物技术股份有限公司 Skincare matrix with functions of moisturizing and relieving sensitive skin as well as preparation and application thereof
CN108852869A (en) * 2018-09-04 2018-11-23 广东科玮生物技术股份有限公司 The skin care compositions of anti-blue light contamination and its application
CN110101614A (en) * 2019-04-18 2019-08-09 广州科恩生物技术有限公司 A kind of fullerene remediation composition and preparation method thereof

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112972360A (en) * 2021-03-03 2021-06-18 上海好肌茵生物科技有限公司 Sensitive repairing composition and preparation method and application thereof
CN112972360B (en) * 2021-03-03 2023-04-07 上海好肌茵生物科技有限公司 Sensitive repairing composition and preparation method and application thereof
CN113476391A (en) * 2021-07-28 2021-10-08 上海梦希生物科技有限公司 Composition for rapidly repairing sunburn and preparation method and application thereof
CN113476394A (en) * 2021-08-04 2021-10-08 上海梦希生物科技有限公司 Composition for effectively regulating dryness and desquamation of skin and preparation method and application thereof
CN113662902A (en) * 2021-09-26 2021-11-19 沃淄(上海)生物科技有限公司 Composition for rapidly repairing skin injury caused by hypoxia and preparation method and application thereof
CN113616561A (en) * 2021-09-27 2021-11-09 上海新高姿化妆品有限公司 Composition with moisturizing and repairing effects and cosmetic
CN113616561B (en) * 2021-09-27 2023-02-10 上海新高姿化妆品有限公司 Composition with moisturizing and repairing effects and cosmetic
CN114053201A (en) * 2021-11-03 2022-02-18 沃淄(上海)生物科技有限公司 Composition for strongly repairing damaged skin lipid membrane and preparation method and application thereof
CN115364006A (en) * 2021-12-29 2022-11-22 皓雨(广州)化妆品制造有限公司 Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product
CN115364006B (en) * 2021-12-29 2024-02-09 皓雨(广州)化妆品制造有限公司 Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product
CN115844757A (en) * 2022-11-21 2023-03-28 宁波伯通伟达生物医药有限公司 Ceramide face cream and preparation method thereof

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