CN115364006A - Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product - Google Patents

Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product Download PDF

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Publication number
CN115364006A
CN115364006A CN202111641670.8A CN202111641670A CN115364006A CN 115364006 A CN115364006 A CN 115364006A CN 202111641670 A CN202111641670 A CN 202111641670A CN 115364006 A CN115364006 A CN 115364006A
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aging
component
rhythm
repair
aging barrier
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CN115364006B (en
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潘武
黄全胜
黄丽琼
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Haoyu Guangzhou Cosmetics Manufacturing Co ltd
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Haoyu Guangzhou Cosmetics Manufacturing Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • A61K8/355Quinones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention relates to the field of A61K8/18, in particular to an anti-aging barrier repairing composition and an anti-aging barrier repairing skin care product. The anti-aging barrier repair composition provided by the invention has the advantages that 10-65 parts of active conditioning component and 5-35 parts of rhythm repair component are adopted, the anti-aging barrier repair composition is high in stability, good in comprehensive anti-aging effect and easy to store, all active components in the system play a synergistic effect to the greatest extent, the generation amount of key factors of physiological rhythm is rebalanced, clock muscle factors are adjusted, anti-inflammation and dermal matrix repair are ensured, metabolism is obviously improved, an interesting nerve beautifying effect is further shown, and the user experience is improved. Meanwhile, the skin aging process is slowed down by reconstructing a fragile mastoid dermis network, the skin photoaging is reduced, the skin compactness is increased, and the skin aging process is slowed down.

Description

Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product
Technical Field
The invention relates to the field of A61K8/18, in particular to an anti-aging barrier repairing composition and an anti-aging barrier repairing skin care product.
Background
Aging is a natural irreversible process, and the appearance of the skin is manifested by skin relaxation, pigmentation, large pores, wrinkle appearance and deepening, and the skin has oxidation resistance, melanin accumulation level, collagen glycosylation level, moisture retention barrier strength and weakness, cell regeneration capacity and collagen aging degree which can represent the aging degree of the skin to a certain extent. With the development of economic society and the improvement of living standard of people, modern people living in the environment of digital electronic products, including adults, young people and even teenagers, generally have the phenomenon of staying up all night, which accelerates the process of skin aging, and causes skin aging problems of dark complexion, color spots, pigmentation, skin relaxation and the like.
Aging is currently dealt with or delayed by mainly enhancing the proliferative metabolic capacity of the skin, reconstructing the extracellular matrix of the skin, resisting ultraviolet radiation, oxidation, glycation, crosslinking, degradation, allergic inflammation, and the like. Therefore, in the prior art, or active ingredients such as nicotinamide, sodium hyaluronate and schizosaccharomyces cerevisiae fermentation product lysate are added to supplement water and oil to maintain water and oil balance, promote cells to newly inhibit tyrosinase activity and melanin generation and repair skin barriers, but the addition of the active ingredients accelerates the growth of bacteria and microorganisms to a certain extent and is easy to form malignant circulation. Or the skin aging is delayed by adding a retinol substance to stimulate the synthesis of collagen, but the retinol compound is easy to decompose and lose efficacy when exposed to light, has low utilization rate, is difficult to store and single in function, and can not effectively solve the skin aging problems such as wrinkles, dark skin color, skin relaxation and the like. At present, the youthfulness, multiple effects and safety of the anti-aging products are new requirements of consumers on the anti-aging products, and are an important guide for the future development of the anti-aging products.
Therefore, the barrier repairing composition which is high in stability, good in comprehensive anti-aging effect and easy to store is provided, the composition is good in matching compatibility, and can be added to prepare anti-aging barrier repairing water, milk, cream, essence, facial masks and other skin care products according to actual requirements, so that the barrier repairing composition has a very high actual application value.
Disclosure of Invention
In order to solve the above problems, in one aspect, the present invention provides an anti-aging barrier repairing composition, which is prepared from at least: 10-65 parts of active conditioning component and 5-35 parts of rhythm repairing component.
As a preferred embodiment, the active conditioning component comprises active conditioning component a, active conditioning component B; the mass ratio of the active conditioning component A to the active conditioning component B is (6-35): (4-30).
As a preferable technical scheme, the active conditioning component A at least comprises 77.5-87.4 percent of safflower seed oil, 6-10 percent of jambu extract, 6-10 percent of astragalus membranaceus root extract, 0.5-2 percent of ubiquinone and 0.1-0.5 percent of tocopherol by weight percentage.
As a preferred technical scheme, the active conditioning component A is prepared by adopting a dynamic cold-warm extraction technology; the active conditioning component A is prepared by adopting a dynamic cold-temperature extraction technology, and the specific method comprises the following steps: grinding safflower seed oil, herba Psychotriae Latifoliae extract, radix astragali extract, ubiquinone and tocopherol at-75-85 deg.C into powder, placing in oxygen-free high pressure environment, and treating with electromagnetic wave and low frequency ultrasonic flow for 10-20 min.
The safflower (Carthamus TINCTORIUS) seed oil, spissus Acmella (Spilanthes Acmella) extract, astragalus MEMBRANACEUS (Astragalus MEMBRANACEUS) root extract, ubiquinone, and tocopherol are derived from Hallstar.
The active conditioning component A comprising safflower seed oil, a jambu extract, an astragalus membranaceus root extract, ubiquinone and tocopherol is prepared by adopting a dynamic cold-warm extraction technology, so that the plant cell membrane is promoted to split, and various rare active molecules which cannot be obtained by the traditional method are released; the release of the most precious and rare high-efficiency active factors from the most core of plant cells is promoted, the efficacy of active substances is remarkably improved, the provided anti-aging barrier repairing composition has the effects of multiple lifting and tightening, muscles are quickly relaxed, the contraction of the skin is inhibited, and the generation of expression lines and wrinkles is reduced.
As a preferable technical scheme, the active conditioning component B at least comprises 15 to 25 percent of alpine edelweiss callus extract, 0.1 to 0.5 percent of xanthan gum and the balance of glycerol in percentage by weight. The preparation method of the active conditioning component B comprises the following steps: adding the extract of the callus of the alpine edelweiss into a container containing glycerol according to the weight percentage, stirring and dispersing for 5-10min, then controlling the temperature to be 40-60 ℃, adding xanthan gum and stirring for 10-15min to obtain the product.
The extract of callus of Leontopodium ALPINUM (Leontopodium ALPINUM) is extracted from Leontopodium ALPINUM, is rich in rare components such as minerals and edetic acid, also called edelweiss, is a herbal plant of Compositae, naturally grows in Belgium, alps and Himalayas, has unique star-shaped flower shape, is very rare, has high self-defense ability, can resist severe weather and other growth environments, has the reputation of "after mountain peak", and is a strictly protected plant.
In the application, the anti-aging barrier repairing composition provided by adding the alpine edelweiss callus extract to the active conditioning component B, and matching with the safflower seed oil, the jambu extract, the astragalus membranaceus root extract and the rosemary leaf extract has the outstanding effects of relaxing skin, repairing dermal matrix and repairing blue light damage, effectively stretching relaxing neck skin and lacrimal duct areas on the upper parts of cheeks, and fading fishtail lines and expression lines.
The glycerol, alpine edelweiss callus extract and xanthan gum are derived from Sederma.
As a preferred technical scheme, the rhythm repairing component comprises a rhythm repairing component A and a rhythm repairing component B; the mass ratio of the rhythm repairing component A to the rhythm repairing component B is (5-32): (0.1-3).
As a preferred technical scheme, the rhythm repairing component a at least comprises the following components in percentage by weight: 20-30%, butanediol: 18-25%, carbomer: 0.1-2%, polysorbate-20: 0.01-1%, palmitoyl tripeptide-1: 0.05-0.2%, palmitoyl tetrapeptide-7: 0.001-0.1% and glycerol as the rest. The preparation method of the rhythm repairing component A comprises the following steps: dispersing butanediol and water into glycerol, adding palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, stirring for 5-10min, controlling temperature at 40-60 deg.C, adding carbomer and polysorbate-20, and stirring for 15-30 min.
The joint regulation repairing component A in the anti-aging barrier repairing composition provided by the application promotes the generation of collagen, glycosaminoglycan and hyaluronic acid, activates the mitochondrial network and promotes the self-repair of skin by introducing palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, and is helpful for reducing the photoaging of skin, increasing the firmness of skin and slowing down the aging process of skin by reconstructing a fragile papillary dermal network.
The glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7 are derived from Sederma.
As a preferred technical scheme, the rhythm repairing component B at least comprises the following solubilizing agents in percentage by weight: 1-5%, plant extract: 0.01-0.5%, rhythmic peptide: 0.01-1%, flavonoid compound: 0.001-0.5% and solvent for the rest. The preparation method of the rhythm repairing component B comprises the following steps: dispersing solubilizer in solvent, adding plant extract, rhythm peptide and flavonoid, and stirring for 15-30 min.
As a preferred technical scheme, the rhythm peptide is selected from at least one of palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-3 and palmitoyl oligopeptide; preferably, the rhythmic peptide is palmitoyl tetrapeptide-7;
as a preferable technical scheme, the flavonoid compound is 5, 7-dihydroxyflavone;
the rhythm repair component B in the anti-aging barrier repair composition rebalances the production amount of key factors (opsin 5, rhythmin 2 and melatonin) of circadian rhythms by adopting palmitoyl tetrapeptide-7 matched with 5,7 dihydroxyflavone and plant extracts, adjusts clock muscle factors, restores the normal metabolism of skin cells, and ensures the law of wakefulness and deep sleep, thereby ensuring the anti-inflammation and the repair of dermal matrixes and obviously improving the metabolism, further showing the interesting nerve beautifying effect and improving the user experience.
As a preferred technical scheme, the plant extract is at least one selected from centella asiatica extract, rosemary leaf extract and glycyrrhiza glabra extract; preferably, the plant extract is rosemary leaf extract (Rosmarinus officinalis); a large number of exploratory tests prove that when the plant extract in the rhythm restoration component B is rosemary leaf extract, the plant extract can play a synergistic effect with safflower seed oil, jambu extract, astragalus membranaceus root extract and alpine edelweiss callus extract in a system to the greatest extent, so that the provided anti-aging barrier repair composition has an outstanding skin relaxation lifting effect, a dermal matrix repair effect and a blue light injury repair effect, the stability of polypeptides such as palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1 and flavonoid active ingredients is remarkably improved, the utilization rate of the active ingredients is improved, the provided anti-aging barrier repair composition has excellent matching compatibility, and anti-aging barrier repair water, milk, cream, essence, facial mask and other skin care products can be added and prepared according to actual requirements, so that the anti-aging barrier repair water, milk, cream, essence, facial mask and other skin care products have good practical application values.
As a preferred technical scheme, the solubilizer is selected from at least one of glycerol, pentanediol and butanediol; preferably, the solubilizer is pentanediol; the solvent is at least one of glycerol and deionized water; preferably, the solvent is glycerol. According to the application, the glycerol is adopted as a solvent to be matched with the pentanediol for solubilization, so that the solubility and the dispersibility of the plant extract, the rhythm peptide and the flavonoid compound are improved, the compatibility and the matching performance of the rhythm repairing component B, the rhythm repairing component A and the active conditioning component are improved, and the stability and the product quality of the anti-aging barrier repairing skin care product are further ensured.
The glycerol, pentanediol, rosemary leaf extract, palmitoyl tetrapeptide-7, 5,7 dihydroxyflavone are derived from Sederma.
As a preferred technical solution, the preparation method of the anti-aging barrier repair composition comprises the following steps: mixing the active conditioning component and rhythm repairing component at 25-35 deg.C for 15-30 min.
The second aspect of the invention provides an anti-aging barrier repairing skin care product containing the anti-aging barrier repairing composition, wherein the anti-aging barrier repairing skin care product is any one of anti-aging barrier repairing water, anti-aging barrier repairing emulsion, anti-aging barrier repairing cream, anti-aging barrier repairing essence and anti-aging barrier repairing mask, and the content of the anti-aging barrier repairing composition in the anti-aging barrier repairing skin care product is 0.1-15wt%.
Has the advantages that:
1. the anti-aging barrier repairing composition provided by the invention has the advantages of high stability, good comprehensive anti-aging effect and easiness in storage, is good in matching compatibility, can be added to prepare anti-aging barrier repairing water, milk, cream, essence, facial mask and other skin care products according to actual requirements, and has extremely high practical application value.
2. The active conditioning component A comprising safflower seed oil, a jambu extract, an astragalus membranaceus root extract, ubiquinone and tocopherol is prepared by adopting a dynamic cold-warm extraction technology, so that the cell membrane of the plant is promoted to split, and various rare active molecules which cannot be obtained by the traditional method are released; the release of the most precious and rare high-efficiency active factors from the most core of plant cells is promoted, the efficacy of active substances is remarkably improved, the provided anti-aging barrier repairing composition has the effects of multiple lifting and tightening, muscles are quickly relaxed, the contraction of the skin is inhibited, and the generation of expression lines and wrinkles is reduced.
3. The joint regulation and repair component A in the anti-aging barrier repair composition provided by the application promotes the generation of collagen, glycosaminoglycan and hyaluronic acid by introducing palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, activates the mitochondrial network and promotes the self-repair of skin, and is beneficial to reducing the photoaging of skin, increasing the firmness of skin and slowing down the aging process of skin by reconstructing a fragile papillary dermal network.
4. The rhythm restoration component B in the anti-aging barrier restoration composition rebalances the production amount of key factors (opsin 5, rhythm protein 2 and melatonin) of circadian rhythm by adopting palmitoyl tetrapeptide-7 in cooperation with 5,7 dihydroxyflavone and plant extracts, adjusts clock muscle factors, restores normal metabolism of skin cells, and the wakefulness and deep sleep laws, ensures anti-inflammation and dermal matrix restoration and remarkably improves metabolism, further shows interesting neuro-cosmetic efficacy, and improves user experience.
5. When the plant extract in the rhythm repair component B is the rosemary leaf extract, the plant extract can play a synergistic effect with safflower seed oil, jambu extract, astragalus membranaceus root extract and alpine edelweiss callus extract in a system to the greatest extent, so that the provided anti-aging barrier repair composition has an outstanding skin relaxation lifting effect, a dermal matrix repair effect and a blue light injury repair effect, the stability of polypeptides such as palmitoyl tetrapeptide-7, palmitoyl tripeptide-1 and flavonoid active ingredients is remarkably improved, the utilization rate of the active ingredients is improved, the provided anti-aging barrier repair composition has excellent matching compatibility, and anti-aging barrier repair water, milk, cream, essence, facial mask and other skin care products can be added and prepared according to actual requirements, so that the anti-aging barrier repair water, milk, cream, essence, facial mask and other skin care products have a good actual application value.
Detailed Description
Example 1
In one aspect, embodiment 1 of the present invention provides an anti-aging barrier repairing composition, which is prepared from the following raw materials in parts by weight: 45 parts of active conditioning component and 25 parts of rhythm repairing component.
The active conditioning component comprises an active conditioning component A and an active conditioning component B; the mass ratio of the active conditioning component A to the active conditioning component B is 25:20.
the active conditioning component A comprises 82.8 percent of safflower seed oil, 8 percent of jambu extract, 8 percent of astragalus membranaceus root extract, 1 percent of ubiquinone and 0.2 percent of tocopherol by weight percentage.
The active conditioning component A is prepared by adopting a dynamic cold-temperature extraction technology, and the specific method comprises the following steps: grinding safflower seed oil, radix Psammosilenes extract, radix astragali extract, ubiquinone and tocopherol at-80 deg.C into powder, placing in oxygen-free high-pressure environment, and treating for 15min by electromagnetic wave and low-frequency ultrasonic flow.
The safflower (Carthamus TINCTORIUS) seed oil, spissus Acmella (Spilanthes Acmella) extract, astragalus MEMBRANACEUS (Astragalus MEMBRANACEUS) root extract, ubiquinone, and tocopherol are derived from Hallstar.
The active conditioning component B comprises 20 percent of alpine edelweiss callus extract, 0.3 percent of xanthan gum and the balance of glycerol by weight percentage. The preparation method of the active conditioning component B comprises the following steps: adding the extract of the callus of the alpine edelweiss into a container containing glycerol according to the weight percentage, stirring and dispersing for 8min, then controlling the temperature to be 50 ℃, adding xanthan gum and stirring for 12min to obtain the product.
The glycerol, alpine edelweiss callus extract and xanthan gum are derived from Sederma.
The rhythm repairing component comprises a rhythm repairing component A and a rhythm repairing component B; the mass ratio of the rhythm repairing component A to the rhythm repairing component B is 23:2.
the rhythm restoration component A comprises 25% of water and butanediol by weight percent: 20% of carbomer: 1%, polysorbate-20: 0.5%, palmitoyl tripeptide-1: 0.1%, palmitoyl tetrapeptide-7: 0.05, and glycerol for supplementing the balance. The preparation method of the rhythm restoration component A comprises the following steps: dispersing butanediol and water into glycerol, adding palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, stirring for 8min, controlling temperature at 50 deg.C, adding carbomer and polysorbate-20, and stirring for 20 min.
The glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7 are derived from Sederma.
The rhythm repairing component B comprises the following components in percentage by weight: 3% of plant extract: 0.1%, rhythmic peptide: 0.75%, flavonoid compound: 0.2% and the balance solvent. The preparation method of the rhythm repairing component B comprises the following steps: dispersing solubilizer in solvent, adding plant extract, rhythm peptide and flavonoid, and stirring for 20 min.
The rhythm peptide is palmitoyl tetrapeptide-7; the flavonoid compound is 5,7 dihydroxyflavone;
the plant extract is rosemary leaf extract (Rosmarinus officinalis).
The solubilizer is pentanediol; the solvent is glycerol.
The glycerol, pentanediol, rosemary leaf extract, palmitoyl tetrapeptide-7, 5,7 dihydroxyflavone are derived from Sederma.
The preparation method of the anti-aging barrier repairing composition comprises the following steps: stirring and mixing the active conditioning component and the rhythm repairing component for 20min at the temperature of 30 ℃ according to the parts by weight.
In a second aspect, the example 1 of the present invention provides an anti-aging barrier repair skin care product comprising the anti-aging barrier repair composition, wherein the anti-aging barrier repair skin care product is an anti-aging barrier repair cream, and the content of the anti-aging barrier repair composition in the anti-aging barrier repair cream is 15%.
Example 2
In one aspect, embodiment 1 of the present invention provides an anti-aging barrier repairing composition, which is prepared from the following raw materials in parts by weight: 45 parts of active conditioning component and 25 parts of rhythm repairing component.
The active conditioning component comprises an active conditioning component A and an active conditioning component B; the mass ratio of the active conditioning component A to the active conditioning component B is 25:20.
the active conditioning component A comprises, by weight, 85% of safflower seed oil, 10% of jambu extract, 10% of astragalus membranaceus root extract, 1% of ubiquinone and 0.2% of tocopherol.
The active conditioning component A is prepared by adopting a dynamic cold-temperature extraction technology, and the specific method comprises the following steps: grinding the safflower seed oil, the jambu extract, the astragalus membranaceus root extract, the ubiquinone and the tocopherol into powder at the temperature of 80 ℃ below zero, placing the powder in an oxygen-free high-pressure environment, and performing electromagnetic wave and low-frequency ultrasonic wave treatment for 15min to obtain the composition.
The safflower (Carthamus TINCTORIUS) seed oil, spissus Acmella (Spilanthes Acmella) extract, astragalus MEMBRANACEUS (Astragalus MEMBRANACEUS) root extract, ubiquinone, and tocopherol are derived from Hallstar.
The active conditioning component B comprises 20 percent of alpine edelweiss callus extract, 0.3 percent of xanthan gum and the balance of glycerol by weight percentage. The preparation method of the active conditioning component B comprises the following steps: adding the extract of the callus of the alpine edelweiss into a container containing glycerol according to the weight percentage, stirring and dispersing for 8min, then controlling the temperature to be 50 ℃, adding xanthan gum and stirring for 12min to obtain the product.
The glycerol, alpine edelweiss callus extract and xanthan gum are derived from Sederma.
The rhythm repairing component comprises a rhythm repairing component A and a rhythm repairing component B; the mass ratio of the rhythm repairing component A to the rhythm repairing component B is 23:2.
the rhythm repairing component A comprises the following components in percentage by weight: 28% and butanediol: 18%, carbomer: 1%, polysorbate-20: 0.5%, palmitoyl tripeptide-1: 0.1%, palmitoyl tetrapeptide-7: 0.05% and glycerol for the rest. The preparation method of the rhythm repairing component A comprises the following steps: dispersing butanediol and water into glycerol, adding palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, stirring for 8min, controlling temperature at 50 deg.C, adding carbomer and polysorbate-20, and stirring for 20 min.
The glycerol, water, butanediol, carbomer, polysorbate-20, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-7 are derived from Sederma.
The rhythm repairing component B comprises a solubilizer: 3% of plant extract: 0.12%, rhythmic peptide: 0.70%, flavonoids: 0.2% and the balance solvent. The preparation method of the rhythm repairing component B comprises the following steps: dispersing solubilizer into solvent, adding plant extract, rhythm peptide and flavonoid, and stirring for 20 min.
The rhythm peptide is palmitoyl tetrapeptide-7; the flavonoid compound is 5,7 dihydroxyflavone;
the plant extract is rosemary leaf extract (Rosmarinus officinalis).
The solubilizer is pentanediol; the solvent is glycerol.
The glycerol, pentanediol, rosemary leaf extract, palmitoyl tetrapeptide-7, 5,7 dihydroxyflavone are derived from Sederma.
The preparation method of the anti-aging barrier repairing composition comprises the following steps: stirring and mixing the active conditioning component and the rhythm repairing component for 20min at the temperature of 30 ℃ according to the parts by weight.
In the second aspect of the embodiment 2 of the present invention, an anti-aging barrier repairing skin care product containing the anti-aging barrier repairing composition is provided, the anti-aging barrier repairing skin care product is an anti-aging barrier repairing emulsion, and the content of the anti-aging barrier repairing composition in the anti-aging barrier repairing emulsion is 10%.
Comparative example 1
Comparative example 1 of the present invention provides an anti-aging barrier repair composition, which is the same as example 1 except that the active conditioning component a is prepared by ordinary mixing.
Comparative example 2
Comparative example 2 of the present invention provides an anti-aging barrier repair composition, which is embodied in the same manner as in example 1, except that the rhythm repair component does not include the active conditioning component B.
Comparative example 3
Comparative example 3 of the present invention provides an anti-aging barrier repair composition, which is the same as example 1 except that the plant extract of the rhythm repair component B is a centella asiatica extract.
Performance test method
1. Low-temperature stability: the anti-aging barrier repairing compositions prepared in the examples and the comparative examples are placed at 0 ℃ for 48h, the appearance of the anti-aging barrier repairing composition is observed after the anti-aging barrier repairing composition is restored to the room temperature, and if the anti-aging barrier repairing composition does not precipitate or delaminate, the low-temperature stability of the anti-aging barrier repairing composition is marked as qualified; if precipitation or delamination of the anti-aging barrier repair composition occurs, the low temperature stability of the anti-aging barrier repair composition is recorded as "off-spec".
2. Heat storage stability: the anti-aging barrier repair compositions prepared in the examples and the comparative examples are placed in a thermostat with the temperature of 40 +/-2 ℃ for 48 hours, taken out, placed in a drier, cooled to room temperature, and if the anti-aging barrier repair composition does not have precipitation or layering phenomenon, the heat storage stability of the anti-aging barrier repair composition is marked as qualified; if the anti-aging barrier repair composition precipitates or delaminates, the thermal storage stability of the anti-aging barrier repair composition is recorded as "off-spec".
3. Centrifugal stability: centrifuging the anti-aging barrier repairing compositions prepared in the examples and the comparative examples for 10min at 4000r/min by using a centrifuge, and if the anti-aging barrier repairing compositions are not layered, recording the centrifugal stability of the anti-aging barrier repairing compositions as qualified; if the anti-aging barrier repair composition delaminates, the anti-aging barrier repair composition centrifugal stability is scored as "off-spec".
Test item Stability at Low temperature Stability in Heat storage Centrifugal stability
Example 1 Qualified Qualified Qualified
Example 2 Qualified Qualified Qualified
Comparative example 1 Fail to be qualified Fail to be qualified Fail to be qualified
Comparative example 2 Fail to be qualified Fail to be qualified Fail to be qualified
Comparative example 3 Fail to be qualified Fail to be qualified Fail to be qualified

Claims (10)

1. The anti-aging barrier repairing composition is characterized by comprising the following raw materials in parts by weight: 10-65 parts of active conditioning component and 5-35 parts of rhythm repairing component.
2. The anti-aging barrier repair composition according to claim 1, wherein the active conditioning component comprises active conditioning component a, active conditioning component B; the mass ratio of the active conditioning component A to the active conditioning component B is (6-35): (4-30).
3. The anti-aging barrier repair composition according to claim 2, wherein the active conditioning component a comprises at least 77.5-87.4% by weight of safflower seed oil, 6-10% by weight of jambu extract, 6-10% by weight of astragalus membranaceus root extract, 0.5-2% by weight of ubiquinone, and 0.1-0.5% by weight of tocopherol.
4. The anti-aging barrier repair composition according to claim 2 or 3, wherein the active conditioning component A is prepared by a dynamic cold-warm extraction technology.
5. The anti-aging barrier repairing composition as claimed in claim 2, wherein the active conditioning component B comprises at least 15-25% by weight of edelweiss callus extract, 0.1-0.5% by weight of xanthan gum, and the balance glycerol.
6. The anti-aging barrier repair composition of claim 1 wherein the rhythm repair component comprises a rhythm repair component a, a rhythm repair component B; the mass ratio of the rhythm repairing component A to the rhythm repairing component B is (5-32): (0.1-3).
7. The anti-aging barrier repair composition according to claim 1, wherein the rhythm repair component a comprises at least water: 20-30%, butanediol: 18-25%, carbomer: 0.1-2%, polysorbate-20: 0.01-1%, palmitoyl tripeptide-1: 0.05-0.2%, palmitoyl tetrapeptide-7: 0.001-0.1% and glycerol as the rest.
8. The anti-aging barrier repair composition according to claim 7, wherein the rhythm repair component A is prepared by the following steps: dispersing butanediol and water into glycerol, adding palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, stirring for 5-10min, controlling temperature to 40-60 deg.C, adding carbomer and polysorbate-20, and stirring for 15-30 min.
9. The anti-aging barrier repair composition according to claim 8, wherein the rhythm repair component B comprises at least a solubilizer in percentage by weight: 1-5%, plant extract: 0.01-0.5%, rhythmic peptide: 0.01-1%, flavonoids: 0.001-0.5% and solvent for the rest.
10. An anti-aging barrier repair skin care product comprising the anti-aging barrier repair composition according to any one of claims 1 to 9, wherein the anti-aging barrier repair skin care product is any one of anti-aging barrier repair water, anti-aging barrier repair emulsion, anti-aging barrier repair cream, anti-aging barrier repair essence and anti-aging barrier repair mask, and the content of the anti-aging barrier repair composition in the anti-aging barrier repair skin care product is 0.1 to 15wt%.
CN202111641670.8A 2021-12-29 2021-12-29 Anti-aging barrier repairing composition and anti-aging barrier repairing skin care product Active CN115364006B (en)

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CN111904906A (en) * 2020-08-05 2020-11-10 兰研(上海)生物科技有限公司 Composition for repairing skin barrier and improving skin resistance and preparation method thereof
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EP2228052A1 (en) * 2009-03-09 2010-09-15 Coty Deutschland GmbH Cosmetic basic composition and use thereof
US20110064832A1 (en) * 2009-08-28 2011-03-17 Mary Kay, Inc. Skin care formulations
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