CN110720476A - Bacteriostatic solid preparation and preparation method thereof - Google Patents

Bacteriostatic solid preparation and preparation method thereof Download PDF

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Publication number
CN110720476A
CN110720476A CN201911049904.2A CN201911049904A CN110720476A CN 110720476 A CN110720476 A CN 110720476A CN 201911049904 A CN201911049904 A CN 201911049904A CN 110720476 A CN110720476 A CN 110720476A
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parts
solid preparation
oil
bacteriostatic
essential oil
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CN201911049904.2A
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Chinese (zh)
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常晓军
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Individual
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/12Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/22Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/24Lauraceae [Laurel family], e.g. laurel, avocado, sassafras, cinnamon or camphor
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40Liliopsida [monocotyledons]
    • A01N65/42Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Agronomy & Crop Science (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Botany (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses an antibacterial solid preparation which comprises the following components in parts by weight: 30-40 parts of honeysuckle, 20-30 parts of houttuynia cordata, 20-30 parts of coptis chinensis, 30-40 parts of dandelion, 20-30 parts of camphor, 20-30 parts of clove oil, 30-40 parts of garlic essential oil, 50-60 parts of peppermint oil, 100-200 parts of deionized water and 100-150 parts of gel auxiliary agent. The invention also discloses a preparation method of the antibacterial solid preparation. The bacteriostatic solid preparation can effectively inhibit bacteria.

Description

Bacteriostatic solid preparation and preparation method thereof
Technical Field
The invention belongs to the technical field of solid preparations, and particularly relates to a bacteriostatic solid preparation and a preparation method thereof.
Background
In daily life, in places such as wardrobes or corners of houses and the like which are not easy to clean, dust is more, a large number of bacteria are easy to breed, mosquitoes are introduced, and health hidden troubles are brought to the life of people. A large number of bacteriostatic solid preparations appear on the market at present, but the bacteriostatic solid preparations contain chemical components harmful to human bodies mostly, or have uneven eliminating effects, so that no satisfactory bacteriostatic agent appears, and the requirements of people cannot be met.
Disclosure of Invention
The invention aims to provide a bacteriostatic solid preparation which can effectively inhibit bacteria.
The invention also aims to provide a preparation method of the antibacterial solid preparation.
The technical scheme adopted by the invention is as follows: the bacteriostatic solid preparation consists of the following components in parts by weight: 30-40 parts of honeysuckle, 20-30 parts of houttuynia cordata, 20-30 parts of coptis chinensis, 30-40 parts of dandelion, 20-30 parts of camphor, 20-30 parts of clove oil, 30-40 parts of garlic essential oil, 50-60 parts of peppermint oil, 100-200 parts of deionized water and 100-150 parts of gel auxiliary agent.
The present invention is also characterized in that,
the bacteriostatic solid preparation consists of the following components in parts by weight: 30 parts of honeysuckle, 20 parts of houttuynia cordata, 20 parts of coptis chinensis, 30 parts of dandelion, 20 parts of camphor, 20 parts of clove oil, 30 parts of garlic essential oil, 50 parts of peppermint oil, 100 parts of deionized water and 100 parts of gel auxiliary agent.
The bacteriostatic solid preparation consists of the following components in parts by weight: 40 parts of honeysuckle, 30 parts of houttuynia cordata, 30 parts of coptis chinensis, 40 parts of dandelion, 30 parts of camphor, 30 parts of clove oil, 40 parts of garlic essential oil, 60 parts of peppermint oil, 200 parts of deionized water and 150 parts of gel auxiliary agent.
A preparation method of an antibacterial solid preparation is specifically implemented according to the following steps:
step 1, extracting each Chinese herbal medicine to obtain an extract;
step 2, stirring and mixing the essential oil and the gel auxiliary agent to obtain a mixture;
and 3, fully stirring the extract obtained in the step 1 and the mixture obtained in the step 2, and freezing to obtain the antibacterial solid preparation.
The step 1 is specifically operated as follows: weighing honeysuckle, houttuynia cordata, coptis chinensis, dandelion and camphor, crushing to powder of 50-60 meshes, adding deionized water into the mixed powder, extracting at 20-50 ℃, centrifuging the extracted extract for 20min in a centrifuge of 10000r/min at 5-8 ℃, and performing rotary evaporation on the obtained supernatant for 20-30 min to obtain the powder extract.
The step 2 specifically comprises the following operations: fully mixing clove oil, garlic essential oil and mint oil, adding a gel auxiliary agent into the mixed essential oil, and placing the mixture in a forming die to obtain a mixture.
The step 3 is specifically operated as follows: and (3) fully stirring the powder extract obtained in the step (1) and the mixture obtained in the step (2), and freezing at the temperature of 0-5 ℃ for 30-40 min to obtain the antibacterial solid preparation.
The invention has the beneficial effects that: according to the antibacterial solid preparation, the celastrus orbiculatus powder, the celastrus angulatus powder, the clove powder, the chrysanthemum powder, the derris powder and the wormwood powder which are natural plant powder are added and experiments prove that the antibacterial solid preparation can effectively remove insects and mosquitoes, in addition, the garlic essential oil is an effective substance for expelling insects, and the substances are prepared into the solid preparation, so that the antibacterial solid preparation is convenient to carry, can be placed in a new house or a new car, is convenient to effectively expel mosquitoes, is low in cost and is easy to popularize.
Detailed Description
The invention provides an antibacterial solid preparation which comprises the following components in parts by weight: the composition comprises the following components in parts by weight: 30-40 parts of honeysuckle, 20-30 parts of houttuynia cordata, 20-30 parts of coptis chinensis, 30-40 parts of dandelion, 20-30 parts of camphor, 20-30 parts of clove oil, 30-40 parts of garlic essential oil, 50-60 parts of peppermint oil, 100-200 parts of deionized water and 100-150 parts of gel auxiliary agent.
Preferably, the bacteriostatic solid preparation consists of the following components in parts by weight: 30 parts of honeysuckle, 20 parts of houttuynia cordata, 20 parts of coptis chinensis, 30 parts of dandelion, 20 parts of camphor, 20 parts of clove oil, 30 parts of garlic essential oil, 50 parts of peppermint oil, 100 parts of deionized water and 100 parts of gel auxiliary agent.
Preferably, the bacteriostatic solid preparation consists of the following components in parts by weight: 40 parts of honeysuckle, 30 parts of houttuynia cordata, 30 parts of coptis chinensis, 40 parts of dandelion, 30 parts of camphor, 30 parts of clove oil, 40 parts of garlic essential oil, 60 parts of peppermint oil, 200 parts of deionized water and 150 parts of gel auxiliary agent.
A preparation method of an antibacterial solid preparation is specifically implemented according to the following steps:
step 1, extracting each Chinese herbal medicine to obtain an extract;
step 2, stirring and mixing the essential oil and the gel auxiliary agent to obtain a mixture;
and 3, fully stirring the extract obtained in the step 1 and the mixture obtained in the step 2, and freezing to obtain the antibacterial solid preparation.
The step 1 is specifically operated as follows: weighing honeysuckle, houttuynia cordata, coptis chinensis, dandelion and camphor, crushing to powder of 50-60 meshes, adding deionized water into the mixed powder, extracting at 20-50 ℃, centrifuging the extracted extract for 20min in a centrifuge of 10000r/min at 5-8 ℃, and performing rotary evaporation on the obtained supernatant for 20-30 min to obtain the powder extract.
The step 2 specifically comprises the following operations: fully mixing clove oil, garlic essential oil and mint oil, adding a gel auxiliary agent into the mixed essential oil, and placing the mixture in a forming die to obtain a mixture.
The step 3 is specifically operated as follows: and (3) fully stirring the powder extract obtained in the step (1) and the mixture obtained in the step (2), and freezing at the temperature of 0-5 ℃ for 30-40 min to obtain the antibacterial solid preparation.
The present invention will be described in detail with reference to the following embodiments.
Example 1
An antibacterial solid preparation is prepared by the following steps: 30 parts of honeysuckle, 20 parts of houttuynia cordata, 20 parts of coptis chinensis, 30 parts of dandelion, 20 parts of camphor, 20 parts of clove oil, 30 parts of garlic essential oil, 50 parts of peppermint oil, 100 parts of deionized water and 100 parts of a gel auxiliary agent; pulverizing weighed flos Lonicerae, herba Houttuyniae, Coptidis rhizoma, herba Taraxaci, and radix Cinnamomi Camphorae to 50 mesh powder, adding deionized water into the mixed powder, extracting at 20 deg.C, centrifuging the extractive solution at 5 deg.C and 10000r/min for 20min, and rotary evaporating the supernatant for 20min to obtain powder extract; fully mixing clove oil, garlic essential oil and mint oil, adding a gel auxiliary agent into the mixed essential oil, and placing the mixture in a forming die to obtain a mixture; and (3) fully stirring the powder extract obtained in the step (1) and the mixture obtained in the step (2), and freezing at 0 ℃ for 30min to obtain the bacteriostatic solid preparation.
Example 2
An antibacterial solid preparation is prepared by the following steps: 40 parts of honeysuckle, 30 parts of houttuynia cordata, 30 parts of coptis chinensis, 40 parts of dandelion, 30 parts of camphor, 30 parts of clove oil, 40 parts of garlic essential oil, 60 parts of peppermint oil, 200 parts of deionized water and 150 parts of gel auxiliary agent; pulverizing weighed flos Lonicerae, herba Houttuyniae, Coptidis rhizoma, herba Taraxaci, and radix Cinnamomi Camphorae to 60 mesh powder, adding deionized water into the mixed powder, extracting at 50 deg.C, centrifuging the extractive solution in centrifuge at 8 deg.C and 10000r/min for 20min, and rotary evaporating the supernatant for 30min to obtain powder extract; fully mixing clove oil, garlic essential oil and mint oil, adding a gel auxiliary agent into the mixed essential oil, and placing the mixture in a forming die to obtain a mixture; and (3) fully stirring the powder extract obtained in the step (1) and the mixture obtained in the step (2), and freezing at 5 ℃ for 40min to obtain the bacteriostatic solid preparation.
Example 3
An antibacterial solid preparation is prepared by the following steps: according to the weight parts, 35 parts of honeysuckle, 25 parts of houttuynia cordata, 25 parts of coptis chinensis, 35 parts of dandelion, 25 parts of camphor, 25 parts of clove oil, 35 parts of garlic essential oil, 55 parts of peppermint oil, 150 parts of deionized water and 110 parts of gel auxiliary agent; pulverizing weighed honeysuckle, houttuynia cordata, coptis chinensis, dandelion and camphor into 55-mesh powder, adding deionized water into the mixed powder, extracting at 35 ℃, centrifuging the extracted extract in a centrifuge at 7 ℃ and 10000r/min for 20min, and performing rotary evaporation on the obtained supernatant for 25min to obtain a powder extract; fully mixing clove oil, garlic essential oil and mint oil, adding a gel auxiliary agent into the mixed essential oil, and placing the mixture in a forming die to obtain a mixture; and (3) fully stirring the powder extract obtained in the step (1) and the mixture obtained in the step (2), and freezing at the temperature of 3 ℃ for 35min to obtain the bacteriostatic solid preparation.
Example 4
An antibacterial solid preparation is prepared by the following steps: 38 parts of honeysuckle, 22 parts of houttuynia cordata, 27 parts of coptis chinensis, 31 parts of dandelion, 20 parts of camphor, 23 parts of clove oil, 30 parts of garlic essential oil, 50 parts of peppermint oil, 170 parts of deionized water and 115 parts of a gel auxiliary agent; pulverizing weighed honeysuckle, houttuynia cordata, coptis chinensis, dandelion and camphor into 56-mesh powder, adding deionized water into the mixed powder, extracting at 38 ℃, centrifuging the extracted extract in a centrifuge at 6 ℃ and 10000r/min for 20min, and performing rotary evaporation on the obtained supernatant for 23min to obtain a powder extract; fully mixing clove oil, garlic essential oil and mint oil, adding a gel auxiliary agent into the mixed essential oil, and placing the mixture in a forming die to obtain a mixture; and (3) fully stirring the powder extract obtained in the step (1) and the mixture obtained in the step (2), and freezing at 4 ℃ for 35min to obtain the bacteriostatic solid preparation.
Example 5
An antibacterial solid preparation is prepared by the following steps: 32 parts of honeysuckle, 26 parts of houttuynia cordata, 21 parts of coptis chinensis, 35 parts of dandelion, 25 parts of cinnamomum camphora, 25 parts of clove oil, 36 parts of garlic essential oil, 55 parts of peppermint oil, 180 parts of deionized water and 116 parts of a gel auxiliary agent; pulverizing weighed honeysuckle, houttuynia cordata, coptis chinensis, dandelion and camphor into powder of 58 meshes, adding deionized water into the mixed powder, extracting at 40 ℃, centrifuging the extracted extract in a centrifuge of 10000r/min at 7 ℃ for 20min, and performing rotary evaporation on the obtained supernatant for 25min to obtain a powder extract; fully mixing clove oil, garlic essential oil and mint oil, adding a gel auxiliary agent into the mixed essential oil, and placing the mixture in a forming die to obtain a mixture; and (3) fully stirring the powder extract obtained in the step (1) and the mixture obtained in the step (2), and freezing at 4 ℃ for 37min to obtain the bacteriostatic solid preparation.

Claims (7)

1. The bacteriostatic solid preparation is characterized by comprising the following components in parts by weight: 30-40 parts of honeysuckle, 20-30 parts of houttuynia cordata, 20-30 parts of coptis chinensis, 30-40 parts of dandelion, 20-30 parts of camphor, 20-30 parts of clove oil, 30-40 parts of garlic essential oil, 50-60 parts of peppermint oil, 100-200 parts of deionized water and 100-150 parts of gel auxiliary agent.
2. The bacteriostatic solid preparation according to claim 1, which is characterized by comprising the following components in parts by weight: 30 parts of honeysuckle, 20 parts of houttuynia cordata, 20 parts of coptis chinensis, 30 parts of dandelion, 20 parts of camphor, 20 parts of clove oil, 30 parts of garlic essential oil, 50 parts of peppermint oil, 100 parts of deionized water and 100 parts of gel auxiliary agent.
3. The bacteriostatic solid preparation according to claim 1, which is characterized by comprising the following components in parts by weight: 40 parts of honeysuckle, 30 parts of houttuynia cordata, 30 parts of coptis chinensis, 40 parts of dandelion, 30 parts of camphor, 30 parts of clove oil, 40 parts of garlic essential oil, 60 parts of peppermint oil, 200 parts of deionized water and 150 parts of gel auxiliary agent.
4. The preparation method of the antibacterial solid preparation is characterized by comprising the following steps:
step 1, extracting each Chinese herbal medicine to obtain an extract;
step 2, stirring and mixing the essential oil and the gel auxiliary agent to obtain a mixture;
and 3, fully stirring the extract obtained in the step 1 and the mixture obtained in the step 2, and freezing to obtain the antibacterial solid preparation.
5. The method for preparing a bacteriostatic solid preparation according to claim 4, wherein the step 1 is specifically operated as follows: weighing honeysuckle, houttuynia cordata, coptis chinensis, dandelion and camphor, crushing to powder of 50-60 meshes, adding deionized water into the mixed powder, extracting at 20-50 ℃, centrifuging the extracted extract for 20min in a centrifuge of 10000r/min at 5-8 ℃, and performing rotary evaporation on the obtained supernatant for 20-30 min to obtain the powder extract.
6. The method for preparing a bacteriostatic solid preparation according to claim 4, wherein the step 2 is specifically operated as follows: fully mixing clove oil, garlic essential oil and mint oil, adding a gel auxiliary agent into the mixed essential oil, and placing the mixture in a forming die to obtain a mixture.
7. The method for preparing a bacteriostatic solid preparation according to claim 4, wherein the step 3 is specifically operated as follows: and (3) fully stirring the powder extract obtained in the step (1) and the mixture obtained in the step (2), and freezing at the temperature of 0-5 ℃ for 30-40 min to obtain the antibacterial solid preparation.
CN201911049904.2A 2019-10-31 2019-10-31 Bacteriostatic solid preparation and preparation method thereof Pending CN110720476A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104255835A (en) * 2014-08-29 2015-01-07 成都顺发消洗科技有限公司 Indoor disinfectant and preparation method thereof
CN104606700A (en) * 2015-01-07 2015-05-13 房静怡 Solid air freshening agent and preparation method thereof
CN105536017A (en) * 2015-12-21 2016-05-04 青岛拓联信息技术有限公司 Solid air freshener
CN107308480A (en) * 2017-06-10 2017-11-03 张志杰 The air freshener of environment friendly bacteriostatic

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104255835A (en) * 2014-08-29 2015-01-07 成都顺发消洗科技有限公司 Indoor disinfectant and preparation method thereof
CN104606700A (en) * 2015-01-07 2015-05-13 房静怡 Solid air freshening agent and preparation method thereof
CN105536017A (en) * 2015-12-21 2016-05-04 青岛拓联信息技术有限公司 Solid air freshener
CN107308480A (en) * 2017-06-10 2017-11-03 张志杰 The air freshener of environment friendly bacteriostatic

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
薛广波: "《现代消毒学》", 31 July 2002, 人民军医出版社 *

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Application publication date: 20200124