CN105147781B - One kind is with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component and its application - Google Patents

One kind is with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component and its application Download PDF

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CN105147781B
CN105147781B CN201510156338.0A CN201510156338A CN105147781B CN 105147781 B CN105147781 B CN 105147781B CN 201510156338 A CN201510156338 A CN 201510156338A CN 105147781 B CN105147781 B CN 105147781B
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gorgon euryale
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euryale kind
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CN105147781A (en
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蔡梅红
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Jiangsu University
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Abstract

It is of the invention a kind of with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component and its application, belong to technical field of food biotechnology.Low temperature drying, crushing extract it with pure water or different concentration ethanol (10%-95%), and be centrifuged after crossing 40-80 mesh screen after Gorgon euryale kind shell is eluriated.Pure water is added after removing solvent up to Gorgon euryale kind shell water extract mixture in supernatant after taking centrifugation, is centrifuged after completely dissolution, and the supernatant after collecting centrifugation is Gorgon euryale kind shell different concentration ethanol extract solution.Honeycomb crushed material adds water, the centrifugation supernatant after 25 DEG C of -37 DEG C of shaking tables act on, as honeycomb Aqueous extracts.Honeycomb Aqueous extracts, vitamin C, Gorgon euryale kind shell Aqueous extracts or Gorgon euryale kind shell different concentration ethanol extract solution, after these three ingredients mix according to a certain ratio, one kind is obtained with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component, has the function of alleviating scytitis especially allergic dermatitis.

Description

One kind is with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component and its application
Technical field
The invention belongs to biological food technical fields, and in particular to one kind is with the suppression as main component of Gorgon euryale kind shell extract Scorching anti-allergy preparation and application.
Background of invention
Gorgon euryale is also known as chicken head, belongs to Nymphaeceae, annual large size aquatic herbaceous plant, it is distributed widely in China various regions.Mesh Before, with the improvement of Gorgon euryale artificial planting technique, the provinces such as Jiangsu, Anhui, Shandong, the area of artificial growth Gorgon euryale gradually increases.Gorgon euryale Kernel after seed removal kind shell is known as Gorgon fruit, it has invigorating the spleen of drying, nourishing blood and tranquilization, supplementing the kidney to control the nocturnal, antidiarrheal only stagnant, improves the heart Dirty ischemic function improves a variety of trophic functions such as antioxidant ability of organism.Therefore, Gorgon fruit is always one welcome by broad masses Kind food with health care function.
It is well known that the kind shell of Gorgon euryale seed is very rigid, generally it is difficult to obtain complete Gorgon fruit particle, this leads to Gorgon fruit Price is constantly in a high position, and the crowd for consumption Gorgon fruit of having the ability is fewer.The good news is in recent years, with gordon euryale seed sheller It invents and is widely used, so that the industrialization of Gorgon fruit, batch production become to be more easier.This market for not only promoting Gorgon fruit supplies Ying Liang, reduces the production cost of Gorgon fruit, and improves the quantity of Gorgon fruit consumer groups.
Currently, the Suzhou in Jiangsu, Yangzhou, one band of Huaian, a band such as the day in Anhui is long, Huainan, Bo continent, Shandong, south, black dragon The various regions such as river, Jilin, Liaoning, Hebei, Zhejiang, Fujian, Jiangxi Gorgon fruit processing factory is more and more, it is followed by that Gorgon fruit adds The processing problem of a large amount of discarded Gorgon euryale kind shells generated during work.Currently, a large amount of Gorgon euryale kind shell is by the random road Dui Qi roadside, sky On the ground, the pollution of ecological environment and the waste of resource are caused.For current status, the present invention is had studied one kind and is mentioned with Gorgon euryale kind shell Take the scorching anti-allergy preparation of object suppression as main component and application.
The invention is natural using discarded Gorgon euryale kind shell preparation, green suppression is scorching, antiallergic substance method, with potential commodity Change, the prospect of industrialized production and market potential demand, it is contemplated that good social benefit, economic benefit and environmental protection effect can be brought Benefit.
Summary of the invention
(1) the technical problem to be solved in the present invention:
Present invention generally provides one kind with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component and application, specific to wrap It includes (1) different solvents (water, ethyl alcohol) extraction Gorgon euryale kind shell and extracts suppression inflammation, the method for antiallergic substance;(2) suppression of Gorgon euryale kind shell extract it is scorching, The determination of antiallergic effect.
Technical solution of the present invention:
Step 1: taking the Gorgon euryale kind shell of Gorgon fruit processing factory, and after elutriation, 37 DEG C or so sufficiently dry.
Step 2: by the Gorgon euryale kind shell after low temperature drying, 40-80 mesh screen is smashed it through through small drug pulverizer.It took Gorgon euryale kind shell powder after sieve, with pure water or different concentration ethanol (10%-95%), 37 DEG C shake under the conditions of that extraction 1-4 is carried out to it is small When.
Step 3: the mixture after taking pure water or different concentration ethanol (10%-95%) extraction Gorgon euryale kind shell powder, 8000 Under the conditions of rpm-12000 rpm, it is centrifuged 10-5 minutes.
Step 4: in collection step three be centrifuged after supernatant, obtain solution i.e. Gorgon euryale kind shell Aqueous extracts (take water as a solvent, it is molten Matter is mainly Gorgon fruit shell polyphenol) or mixture one (using different concentration ethanol as solvent, solute is mainly Gorgon fruit shell polyphenol).
Step 5: by mixture once vacuum rotary evaporator processing, after removing solvent therein, the bottom of rotary distillation bottle There is one layer of solid fraction mixture two in portion.
Step 6: being added pure water in solid mixt two, after completely dissolution, under the conditions of 8000 rpm-12000 rpm from The heart 10-5 minutes.
Step 7: the supernatant after being centrifuged in collection step six, obtained solution is that Gorgon euryale kind shell different concentration ethanol mentions Take object solution.
Step 8: honeycomb processing is clean, crushes after low temperature drying, and through 80 mesh net filtrations, taking minus sieve powder is to mix Object three
Step 9: being in proportion the condition of 1:5-1:15, after mixture three and pure water are mixed, is put into 25 DEG C -37 DEG C and shakes After bed effect 1-3 hours, it is centrifuged under the conditions of 8000-12000 per minute turns, supernatant is taken to obtain honeycomb Aqueous extracts.
Step 10: it is prepared by consisting of a kind of with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component: honeycomb Aqueous extracts 0.1%-5% of the total volume, Gorgon euryale kind shell Aqueous extracts or Gorgon euryale kind shell different concentration ethanol extract solution account for 90%- 98.9%, vitamin C accounts for 1%-5%.
(2) present invention the beneficial effect is that:
Gorgon euryale kind shell is the waste in a kind of Gorgon fruit manufacturing enterprise processing Gorgon fruit engineering, these discarded Gorgon euryale kind shells do not have at present There is the method rationally utilized, can only arbitrarily be abandoned, cause environmental pollution and the wasting of resources.The present invention develops one kind for the first time With the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component, and the invention also has many beneficial effects.Specific benefit is such as Under:
(1) Business Economic Benefit is improved:
The present invention makes Gorgon fruit processing waste -- and Gorgon euryale kind shell is turned waste into wealth, and is increased the added value of Gorgon fruit, is improved Gorgon fruit The economic benefit of processing enterprise.
(2) it reduces environmental pollution, economizes the land resource:
The present invention makes full use of Gorgon fruit processing waste -- and Gorgon euryale kind shell extracts suppression inflammation, antiallergic substance, this becomes Gorgon euryale kind shell At dotey.Gorgon fruit processing enterprise can be deposited in these Gorgon euryale kind shells to sell in warehouse, without arbitrarily they are regarded Rubbish is arbitrarily stacked outdoors, is allowed to corruption, fermentation.Therefore, The present invention reduces arbitrarily being stacked because of Gorgon euryale kind shell caused by pollute The waste of environment and land resource.
(3) social benefit:
It is over the past thousands of years the favorite food of numerous people that Gorgon fruit, which is a kind of,.The present invention utilizes Gorgon fruit processing waste-Gorgon euryale kind Shell develops the production method of the new green of one kind, scorching, antiallergic substance the method for the suppression of safety, develops novel, ring for next step Allergic dermatitis inhibitor is protected to lay a good foundation.Suppression prepared by the present invention is scorching, antiallergic substance comes from raw-food material, can be used for baby children The crowd of the different age groups such as youngster, has no toxic side effect, it is expected to bring preferable social benefit.
Detailed description of the invention
Fig. 1: a kind of that allergy caused by solar radiation is alleviated with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component The research of property dermatitis symptom (see embodiment 1)
A, allergic dermatitis symptom caused by solar radiation
B, it is a kind of that anaphylaxis caused by solar radiation is embrocated with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component The 48 hours later situations in dermatitis position.
Specific embodiment
Embodiment 1 is a kind of with the scorching anti-allergy preparation Reduce allergy dermatitis symptom of Gorgon euryale kind shell extract suppression as main component Research
The processing of 1 Gorgon euryale kind shell
In the Anhui day long queue hilllock big market of Gorgon fruit, the Gorgon fruit processing waste arbitrarily stacked outdoors is taken -- Gorgon euryale kind shell 30 is public Jin.Firstly, 1 kilogram or so of Gorgon euryale kind shell is taken to be eluriated in clean tap water, remove residual in a little Gorgon fruit process Stay in the broken Gorgon fruit particle in Gorgon euryale kind shell.Then, clean Gorgon euryale kind shell will be eluriated to be put into 37 DEG C of baking ovens, it is small is dried 24 When or so.Then, small drug pulverizer is put by several, the Gorgon euryale kind shell after drying point sufficiently to crush.Finally, by Gorgon euryale kind shell powder It minces and is sieved with 40 mesh sieve, removal crushes incomplete Gorgon euryale kind shell particle, collects the Gorgon euryale kind shell that can pass through 40 mesh sieve Powder is spare.
A kind of preparation with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component
10 grams of Gorgon euryale kind shell powder are weighed, is put into the beaker that capacity is 100 milliliters or so, 10 grams of pure water is added, makes pure Water immersion Gorgon euryale kind shell powder.Beaker is all wrapped up with masking foil, and is tightened beaker mouth with rubber band.Beaker is put into 37 DEG C shaking table shakes 1 hour under the conditions of 120 rpm.
The Gorgon euryale kind shell water extract after shaking 1 hour is taken, is centrifuged 5 minutes under the conditions of 12000 rpm, after collecting centrifugation To get Gorgon euryale kind shell water extract, (solute is mainly Gorgon fruit shell polyphenol to supernatant, and the result of high effective liquid chromatography for measuring obtains after being computed Out, about 1 gram of the content containing polyphenol in 10 grams of Gorgon euryale kind shells).
Honeycomb processing is clean, crushes after low temperature drying, through 80 mesh net filtrations, taking minus sieve powder is mixture three.It presses Ratio is the condition of 1:5, after mixture three and pure water are mixed, after being put into 25 DEG C of shaking tables effects 1 hour, at 8000 turns per minute Under the conditions of be centrifuged, take supernatant to obtain honeycomb Aqueous extracts.
Prepare by consisting of a kind of with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component: honeycomb Aqueous extracts account for The 0.1% of total volume, Gorgon euryale kind shell water extract account for 98.9%, and vitamin C accounts for 1%.
One kind alleviating anaphylaxis skin caused by solar radiation with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component Scorching studies on some in dications of (Fig. 1)
(1) after on the inside of volunteer patients' elbow because of summer sun irradiation, scratchiness is strong, and red and swollen, coarse, skin temperature occurs in part The case where degree increases.Due to, to day photosensitization, causing allergic dermatitis position to there are some cytochromes to lose, out on the inside of patient's elbow The white point to differ in size is showed.
(2) with freshly prepared a kind of with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component, spraying volunteer Allergic inflammation position on the inside of elbow, it is primary every 2 hours, every 24 hours 6-8 times.
After (3) 48 hours, it is found that the symptom of the allergic inflammation on the inside of volunteer's elbow is substantially reduced, shows themselves in that skin is swollen Swollen symptom disappears, and touches dermal sensation smoother.Skin red heat situation is substantially reduced, and patient's scratchiness disappears, and nothing is obvious not Suitable sense.
Embodiment 2 is a kind of to alleviate tetanus antitoxin skin with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component Allergic dermatitis studies on some in dications of caused by trying
The processing of 1 Gorgon euryale kind shell
In the Anhui day long queue hilllock big market of Gorgon fruit, the Gorgon fruit processing waste arbitrarily stacked outdoors is taken -- Gorgon euryale kind shell 30 is public Jin.Firstly, 1 kilogram or so of Gorgon euryale kind shell is taken to be eluriated in clean tap water, remove residual in a little Gorgon fruit process Stay in the broken Gorgon fruit particle in Gorgon euryale kind shell.Then, clean Gorgon euryale kind shell will be eluriated to be put into 37 DEG C of baking ovens, it is small is dried 24 When or so.Then, small drug pulverizer is put by several, the Gorgon euryale kind shell after drying point sufficiently to crush.Finally, by Gorgon euryale kind shell powder It minces and is sieved with 80 mesh sieve, removal crushes incomplete Gorgon euryale kind shell particle, collects the Gorgon euryale kind shell that can pass through 80 mesh sieve Powder is spare.
A kind of preparation with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component
10 grams of Gorgon euryale kind shell powder are weighed, is put into the beaker that capacity is 100 milliliters or so, 10 grams of pure water is added, makes pure Water immersion Gorgon euryale kind shell powder.Beaker is all wrapped up with masking foil, and is tightened beaker mouth with rubber band.Beaker is put into 37 DEG C shaking table shakes 4 hours under the conditions of 120 rpm.
Take 95% alcohol extract of Gorgon euryale kind shell after shaking 4 hours, be centrifuged 10 minutes under the conditions of 8000 rpm, collect from Supernatant after the heart is to get mixture one.
By mixture once vacuum rotary evaporator processing, after removing solvent therein, the bottom of rotary distillation bottle occurs One layer of solid mixt two.Pure water is added in solid mixt two, is substantially dissolved in it in pure water, and in 8000 rpm items It is centrifuged 10 minutes under part.Supernatant after taking centrifugation, obtained solution are that (solute is mainly 95% ethanol extract of Gorgon euryale kind shell Gorgon fruit shell polyphenol, the result of high effective liquid chromatography for measuring obtain after being computed, the content containing polyphenol about 1 in 10 grams of Gorgon euryale kind shells Gram).
Honeycomb processing is clean, crushes after low temperature drying, through 80 mesh net filtrations, taking minus sieve powder is mixture three.It presses Ratio is the condition of 1:8, after mixture three and pure water are mixed, after being put into 30 DEG C of shaking tables effects 2 hours, per minute 10000 It is centrifuged under the conditions of turning, supernatant is taken to obtain honeycomb Aqueous extracts.
Prepare by consisting of a kind of with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component: honeycomb Aqueous extracts account for The 2.5% of total volume, 95% ethanol extract of Gorgon euryale kind shell account for 95%, and vitamin C accounts for 2.5%.
One kind is alleviated caused by tetanus antitoxin skin test with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component Allergic dermatitis studies on some in dications of
(1) it on the inside of volunteer (inventor) forearm for having tetanus antitoxin allergies, is subcutaneously injected containing 15U's Tetanus antitoxin (TAT) solution 0.1ml(TAT skin test).After 0.5 hour, discovery volunteer's forearm skin test injection site has directly The red allergy region (to there is punctation region as allergy erythema region) of about 2.0 cm of diameter, without obvious tumefaction, also without scabies Gargalesthesia.
(2) skin test about 1 hour when, volunteer's skin test site has scratchiness, and after scratching, scratchiness weakens, but skin test Position occur obviously harden, swelling.At this point, it is main for sufficiently picking the Gorgon euryale kind shell extract prepared in the present invention with aseptic cotton carrier The suppression inflammation anti-allergy preparation of ingredient smears skin test site, applies once, 9 times a day within hereafter every 2 hours.
(3) after coating 48 hours, the allergy erythema area of volunteer's skin test site is gradually become smaller, and swelling symptom gradually disappears Lose and alleviate, and volunteer feel skin test site without itch, pain, the senses of discomfort such as hot, swollen.This 95% ethanol extract of explanation is alleviated to broken Allergic symptom caused by cold antitoxin skin test is significantly improved.
Embodiment 3 is a kind of with the research as main component for pressing down scorching anti-allergy preparation and alleviating dermatitis symptom of Gorgon euryale kind shell extract
The processing of 1 Gorgon euryale kind shell
In the Anhui day long queue hilllock big market of Gorgon fruit, the Gorgon fruit processing waste arbitrarily stacked outdoors is taken -- Gorgon euryale kind shell 30 is public Jin.Firstly, 1 kilogram or so of Gorgon euryale kind shell is taken to be eluriated in clean tap water, remove residual in a little Gorgon fruit process Stay in the broken Gorgon fruit particle in Gorgon euryale kind shell.Then, clean Gorgon euryale kind shell will be eluriated to be put into 37 DEG C of baking ovens, it is small is dried 24 When or so.Then, small drug pulverizer is put by several, the Gorgon euryale kind shell after drying point sufficiently to crush.Finally, by Gorgon euryale kind shell powder It minces and is sieved with 80 mesh sieve, removal crushes incomplete Gorgon euryale kind shell particle, collects the Gorgon euryale kind shell that can pass through 80 mesh sieve Powder is spare.
A kind of preparation with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component
10 grams of Gorgon euryale kind shell powder are weighed, is put into the beaker that capacity is 100 milliliters or so, 10 grams of pure water is added, makes pure Water immersion Gorgon euryale kind shell powder.Beaker is all wrapped up with masking foil, and is tightened beaker mouth with rubber band.Beaker is put into 37 DEG C shaking table shakes 4 hours under the conditions of 120 rpm.
Take 10% alcohol extract of Gorgon euryale kind shell after shaking 4 hours, be centrifuged 10 minutes under the conditions of 8000 rpm, collect from Supernatant after the heart is to get mixture one.
By mixture once vacuum rotary evaporator processing, after removing solvent therein, the bottom of rotary distillation bottle occurs One layer of solid mixt two.Pure water is added in solid mixt two, is substantially dissolved in it in pure water, and in 8000 rpm items It is centrifuged 10 minutes under part.Supernatant after taking centrifugation, obtained solution are that (solute is mainly 10% ethanol extract of Gorgon euryale kind shell Gorgon fruit shell polyphenol, the result of high effective liquid chromatography for measuring obtain after being computed, the content containing polyphenol about 1 in 10 grams of Gorgon euryale kind shells Gram).
Honeycomb processing is clean, crushes after low temperature drying, through 80 mesh net filtrations, take minus sieve powder be three, of mixture by Ratio is the condition of 1:15, after mixture three and pure water are mixed, after being put into 37 DEG C of shaking tables effects 3 hours, per minute 12000 It is centrifuged under the conditions of turning, supernatant is taken to obtain honeycomb Aqueous extracts.
Prepare by consisting of a kind of with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component: honeycomb Aqueous extracts account for The 5% of total volume, 10% ethanol extract of Gorgon euryale kind shell account for 90%, and vitamin C accounts for 5%.
A kind of research for alleviating children's dermatitis symptom with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component
(1) 9 week old or so suffers from the child of perianal dermatitis, and apparent redness occurs in dermatitis position, and has small erythema Occur.There are obvious burning heat sensation, pain in patient's readme dermatitis position, and sense of discomfort is strong, influences normal walking;
(2) aseptic cotton carrier is dipped one kind with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component at dermatitis position Gently wipe 2-5 times back and forth.It is primary every wiping in 4 hours;
(3) it embrocates by 3 times with the scorching anti-allergy preparation of Gorgon euryale kind shell extract suppression as main component, the rubescent feelings at dermatitis position Condition and pain, burning heat sensation have and significantly improve, and the erythema at former dermatitis position also becomes smaller.Embrocate the suppression inflammation antiallergic prepared in the present invention After preparation 72 hours, child's perianal area is almost recovered without rubescent, no pain, no erythema symptom, dermatitis symptom.

Claims (1)

1. a kind of preparation method of the scorching anti-allergy preparation of the suppression as the main component with Gorgon euryale kind shell extract, it is characterised in that according to following Step carries out:
The wherein suppression inflammation anti-allergy preparation as the main component with Gorgon euryale kind shell extract,
By following weight fraction at being grouped as:
0.1-5 parts of honeycomb Aqueous extracts,
90-98.9 parts of different concentration ethanol extract solution of Gorgon euryale kind shell Aqueous extracts or Gorgon euryale kind shell,
1-5 parts of vitamin C;
(1): taking the Gorgon euryale kind shell of Gorgon fruit processing factory, after elutriation, 37 DEG C sufficiently dry;
(2): by the Gorgon euryale kind shell after low temperature drying, smashing it through 40-80 mesh screen through small drug pulverizer;Take Gorgon euryale after being sieved Kind of shell powder, with pure water or 10%-95% different concentration ethanol, 37 DEG C shake under the conditions of extraction 1-4 hours is carried out to it;
(3): above-mentioned pure water or 10%-95% different concentration ethanol being taken to extract the mixture after Gorgon euryale kind shell powder, 8000 rpm- Under the conditions of 12000 rpm, it is centrifuged 5-10 minutes;
(4): the supernatant after being centrifuged in collection step three obtains solution i.e. Gorgon euryale kind shell Aqueous extracts or mixture one, described mixed Object one is closed using different concentration ethanol as solvent, solute is mainly Gorgon fruit shell polyphenol;
(5): by mixture once vacuum rotary evaporator processing, after removing solvent therein, the bottom of rotary distillation bottle occurs One layer of solid mixt two;
(6): pure water being added in solid mixt two, after completely dissolution, is centrifuged 5-10 under the conditions of 8000 rpm-12000 rpm Minute;
(7): the supernatant after being centrifuged in collection step six, obtained solution is that Gorgon euryale kind shell different concentration ethanol extract is molten Liquid;
(8): honeycomb processing is clean, crushes after low temperature drying, through 80 mesh net filtrations, taking minus sieve powder is mixture three;
(9): being in proportion the condition of 1:5-1:15, after mixture three and pure water are mixed, be put into 25 DEG C of -37 DEG C of shaking tables effects After 1-3 hours, it is centrifuged under the conditions of 8000-12000 per minute turns, supernatant is taken to obtain honeycomb Aqueous extracts;
(10): preparing a kind of suppression inflammation anti-allergy preparation as the main component with Gorgon euryale kind shell extract: honeycomb Aqueous extracts by consisting of 0.1%-5% of the total volume, Gorgon euryale kind shell Aqueous extracts or Gorgon euryale kind shell different concentration ethanol extract solution account for 90%-98.9%, dimension life Plain C accounts for 1%-5%;
Wherein Gorgon euryale kind shell crushed material obtains Gorgon euryale kind shell powder after the sieving of 20-80 mesh sieve in step 2;
(4) Gorgon euryale kind shell Aqueous extracts take water as a solvent in, and solute is mainly Gorgon fruit shell polyphenol, the knot of high effective liquid chromatography for measuring Fruit obtains after being computed, 1 gram of content in 10 grams of Gorgon euryale kind shells containing polyphenol.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103830331A (en) * 2014-03-17 2014-06-04 江苏大学 Method for preparing dermatitis-inhibiting formulation
CN104027397A (en) * 2014-03-25 2014-09-10 江苏大学 Preparation method and application of anti-allergic agent from both medicinal and edible plant extract

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103830331A (en) * 2014-03-17 2014-06-04 江苏大学 Method for preparing dermatitis-inhibiting formulation
CN104027397A (en) * 2014-03-25 2014-09-10 江苏大学 Preparation method and application of anti-allergic agent from both medicinal and edible plant extract

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
蜜蜂巢脾水提液的抗炎活性;褚亚芳等;《食品与生物技术学报》;20110930;第30卷(第5期);第648-652页 *

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