CN110709063A - 具有与吸入器一起使用的颗粒的容器 - Google Patents

具有与吸入器一起使用的颗粒的容器 Download PDF

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Publication number
CN110709063A
CN110709063A CN201880037255.1A CN201880037255A CN110709063A CN 110709063 A CN110709063 A CN 110709063A CN 201880037255 A CN201880037255 A CN 201880037255A CN 110709063 A CN110709063 A CN 110709063A
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CN
China
Prior art keywords
container
particles
capsule
nicotine
microns
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201880037255.1A
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English (en)
Chinese (zh)
Inventor
G·聚贝
J·沃勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Philip Morris Products SA
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Philip Morris Products SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products SA filed Critical Philip Morris Products SA
Priority to CN202410125766.6A priority Critical patent/CN117958505A/zh
Publication of CN110709063A publication Critical patent/CN110709063A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/305—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances of undetermined constitution characterised by their preparation
    • A24B15/306—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances of undetermined constitution characterised by their preparation one reactant being an amino acid or a protein, e.g. Maillard's reaction
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/34—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a carbocyclic ring other than a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/36—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring
    • A24B15/40—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms
    • A24B15/403—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms having only oxygen as hetero atoms
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/42—Cartridges or containers for inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
    • A24F42/20—Devices without heating means
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
    • A24F42/60—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Otolaryngology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CN201880037255.1A 2017-06-28 2018-06-26 具有与吸入器一起使用的颗粒的容器 Pending CN110709063A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202410125766.6A CN117958505A (zh) 2017-06-28 2018-06-26 包含粉末系统的用在吸入器中的容器以及系统

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17178416.8 2017-06-28
EP17178416 2017-06-28
PCT/IB2018/054720 WO2019003118A1 (en) 2017-06-28 2018-06-26 CONTAINER WITH PARTICLES FOR USE WITH INHALER

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202410125766.6A Division CN117958505A (zh) 2017-06-28 2018-06-26 包含粉末系统的用在吸入器中的容器以及系统

Publications (1)

Publication Number Publication Date
CN110709063A true CN110709063A (zh) 2020-01-17

Family

ID=59253389

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201880037255.1A Pending CN110709063A (zh) 2017-06-28 2018-06-26 具有与吸入器一起使用的颗粒的容器
CN202410125766.6A Pending CN117958505A (zh) 2017-06-28 2018-06-26 包含粉末系统的用在吸入器中的容器以及系统

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202410125766.6A Pending CN117958505A (zh) 2017-06-28 2018-06-26 包含粉末系统的用在吸入器中的容器以及系统

Country Status (15)

Country Link
US (1) US12263242B2 (https=)
EP (1) EP3644962A1 (https=)
JP (2) JP2020527377A (https=)
KR (2) KR20240119177A (https=)
CN (2) CN110709063A (https=)
AU (1) AU2018292732B2 (https=)
BR (1) BR112019025635A2 (https=)
CA (1) CA3061895A1 (https=)
IL (1) IL269275B2 (https=)
MX (1) MX2019014671A (https=)
MY (1) MY200258A (https=)
PH (1) PH12019502100A1 (https=)
UA (1) UA126238C2 (https=)
WO (1) WO2019003118A1 (https=)
ZA (1) ZA201905999B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220132939A1 (en) * 2020-11-04 2022-05-05 Anthony Hamilton E-Cigarette Vaporizer Cartridge Filling Device
CN116096253A (zh) * 2020-09-03 2023-05-09 菲利普莫里斯生产公司 低吸湿性活性粉末组合物

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KR102523677B1 (ko) * 2016-06-30 2023-04-20 필립모리스 프로덕츠 에스.에이. 니코틴 입자 및 조성물
CA3125779A1 (en) * 2019-01-07 2020-07-16 Fritz Schmitt Process for producing a gaseous active ingredient or a gaseous active ingredient mixture, kit for use therein and gaseous composition
KR20210129152A (ko) * 2019-03-19 2021-10-27 아쿠아 뱅크 주식회사 서플리먼트 흡인 겸 수소 흡인 장치
EP3794996A1 (en) * 2019-09-20 2021-03-24 Nerudia Limited Smoking substitute apparatus
JP7641272B2 (ja) * 2019-09-26 2025-03-06 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム ねじれた遠位端要素を備えた吸入器物品
ES2965397T3 (es) 2019-11-14 2024-04-15 Philip Morris Products Sa Formulación mejorada de polvo seco con sabor a tabaco
EP4185354B1 (en) * 2020-07-24 2024-05-01 Philip Morris Products S.A. Inhaler article
JP2023552275A (ja) * 2020-12-11 2023-12-15 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 単一平面穿孔要素を備える吸入器システム
US20240024592A1 (en) * 2020-12-18 2024-01-25 Philip Morris Products, S.A. Inhaler article and capsule for use with the same
CN117794397A (zh) * 2021-08-19 2024-03-29 菲利普莫里斯生产公司 由两种颗粒材料形成的呈固体单一体形式的气溶胶形成基质
WO2023178643A1 (zh) * 2022-03-25 2023-09-28 云南中烟工业有限责任公司 一种不使用多通孔固件段的颗粒型气溶胶生成制品
WO2024090892A1 (ko) * 2022-10-27 2024-05-02 주식회사 케이티앤지 흡입용 니코틴 건조 분말의 제조 방법
CN120500327A (zh) * 2022-10-27 2025-08-15 韩国烟草人参公社 用于吸入的低剂量尼古丁干粉组合物
WO2025213000A1 (en) * 2024-04-05 2025-10-09 ODS Products, LLC Pouches comprising active ingredients

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US3634582A (en) * 1967-08-08 1972-01-11 Fisons Pharmaceuticals Ltd Pharmaceutical compositions
US6234169B1 (en) * 1998-08-14 2001-05-22 Arthur Slutsky Inhaler
CN1741789A (zh) * 2002-12-31 2006-03-01 尼克塔治疗公司 具有不溶解的活性物质的药物制剂
US20060254583A1 (en) * 2003-03-20 2006-11-16 Arthur Deboeck Dry powder inhaler system
US20110277752A1 (en) * 2007-12-05 2011-11-17 Novartis Ag Receptacle for an aerosolizable pharmaceutical formulation
EP2614848A1 (de) * 2012-01-13 2013-07-17 Boehringer Ingelheim International GmbH Inhalator und Kapsel für einen Inhalator
CN104981264A (zh) * 2012-12-04 2015-10-14 塞维塔斯治疗股份有限公司 用于刺穿胶囊以从胶囊释放粉状药物的装置和方法
CN105828819A (zh) * 2014-04-08 2016-08-03 桑萨（巴巴多斯）公司 烟碱制剂及其制备方法
WO2015166350A2 (en) * 2014-04-28 2015-11-05 Philip Morris Products S.A. Flavoured nicotine powder inhaler
US20170071856A1 (en) * 2015-09-16 2017-03-16 Sansa Corporation (Barbados) Inc. Inhalable Nicotine Formulations and Methods of Making and Using the Same
CN106539793A (zh) * 2015-09-16 2017-03-29 桑萨（巴巴多斯）公司 烟碱制剂及其制备和使用方法
US20170172996A1 (en) * 2015-09-16 2017-06-22 Sansa Corporation (Barbados) Inc. Inhalable Nicotine Formulations, and Methods of Making and Using Thereof
WO2017109678A1 (en) * 2015-12-24 2017-06-29 Philip Morris Products S.A. Nicotine particle capsule

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116096253A (zh) * 2020-09-03 2023-05-09 菲利普莫里斯生产公司 低吸湿性活性粉末组合物
US20220132939A1 (en) * 2020-11-04 2022-05-05 Anthony Hamilton E-Cigarette Vaporizer Cartridge Filling Device
US12096803B2 (en) * 2020-11-04 2024-09-24 Anthony Hamilton E-cigarette vaporizer cartridge filling device

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RU2019141658A3 (https=) 2021-10-14
IL269275B (en) 2022-12-01
UA126238C2 (uk) 2022-09-07
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IL269275A (en) 2019-11-28
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MY200258A (en) 2023-12-17
BR112019025635A2 (pt) 2020-06-23
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ZA201905999B (en) 2021-01-27
JP2023078269A (ja) 2023-06-06

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