CA3061895A1 - Container with particles for use with inhaler - Google Patents

Container with particles for use with inhaler Download PDF

Info

Publication number
CA3061895A1
CA3061895A1 CA3061895A CA3061895A CA3061895A1 CA 3061895 A1 CA3061895 A1 CA 3061895A1 CA 3061895 A CA3061895 A CA 3061895A CA 3061895 A CA3061895 A CA 3061895A CA 3061895 A1 CA3061895 A1 CA 3061895A1
Authority
CA
Canada
Prior art keywords
particles
capsule
container
nicotine
inhaler
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3061895A
Other languages
English (en)
French (fr)
Inventor
Gerard Zuber
Judith Waller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Philip Morris Products SA
Original Assignee
Philip Morris Products SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products SA filed Critical Philip Morris Products SA
Publication of CA3061895A1 publication Critical patent/CA3061895A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/305—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances of undetermined constitution characterised by their preparation
    • A24B15/306—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances of undetermined constitution characterised by their preparation one reactant being an amino acid or a protein, e.g. Maillard's reaction
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/34—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a carbocyclic ring other than a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/36—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring
    • A24B15/40—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms
    • A24B15/403—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms having only oxygen as hetero atoms
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/42—Cartridges or containers for inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
    • A24F42/20—Devices without heating means
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
    • A24F42/60—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Otolaryngology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CA3061895A 2017-06-28 2018-06-26 Container with particles for use with inhaler Pending CA3061895A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17178416.8 2017-06-28
EP17178416 2017-06-28
PCT/IB2018/054720 WO2019003118A1 (en) 2017-06-28 2018-06-26 CONTAINER WITH PARTICLES FOR USE WITH INHALER

Publications (1)

Publication Number Publication Date
CA3061895A1 true CA3061895A1 (en) 2019-01-03

Family

ID=59253389

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3061895A Pending CA3061895A1 (en) 2017-06-28 2018-06-26 Container with particles for use with inhaler

Country Status (15)

Country Link
US (1) US12263242B2 (https=)
EP (1) EP3644962A1 (https=)
JP (2) JP2020527377A (https=)
KR (2) KR20200023285A (https=)
CN (2) CN117958505A (https=)
AU (1) AU2018292732B2 (https=)
BR (1) BR112019025635A2 (https=)
CA (1) CA3061895A1 (https=)
IL (1) IL269275B2 (https=)
MX (1) MX2019014671A (https=)
MY (1) MY200258A (https=)
PH (1) PH12019502100A1 (https=)
UA (1) UA126238C2 (https=)
WO (1) WO2019003118A1 (https=)
ZA (1) ZA201905999B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3055891T3 (en) * 2016-06-30 2026-02-16 Philip Morris Products Sa Nicotine particles and compositions
US12153059B2 (en) 2019-01-07 2024-11-26 Luxcan Innovation S.A. Process for producing a gaseous active ingredient or a gaseous active ingredient mixture, kit for use therein and gaseous composition
WO2020189787A1 (ja) * 2019-03-19 2020-09-24 隆 竹原 サプリメント吸引兼水素吸引装置
EP3794996A1 (en) * 2019-09-20 2021-03-24 Nerudia Limited Smoking substitute apparatus
EP4033926B1 (en) * 2019-09-26 2023-06-28 Philip Morris Products S.A. Inhaler article with a twisted distal end element
UA130281C2 (uk) * 2019-11-14 2026-01-07 Філіп Морріс Продактс С.А. Сухий порошковий склад зі смаком тютюну, спосіб його одержання та порошкова система
CN116137819B (zh) * 2020-07-24 2026-04-21 菲利普莫里斯生产公司 吸入器制品
US12594238B2 (en) * 2020-09-03 2026-04-07 Philip Morris Products S.A. Low hygroscopicity active powder compositions
US12096803B2 (en) * 2020-11-04 2024-09-24 Anthony Hamilton E-cigarette vaporizer cartridge filling device
WO2022123488A1 (en) * 2020-12-11 2022-06-16 Philip Morris Products S.A. Inhaler system with single plane piercing element
WO2022130091A1 (en) * 2020-12-18 2022-06-23 Philip Morris Products S.A. Inhaler article and capsule for use with the same
WO2023021194A1 (en) * 2021-08-19 2023-02-23 Philip Morris Products S.A. Aerosol-forming substrate in the form of solid unitary body from two particulate materials
WO2023178643A1 (zh) * 2022-03-25 2023-09-28 云南中烟工业有限责任公司 一种不使用多通孔固件段的颗粒型气溶胶生成制品
WO2024090890A1 (ko) * 2022-10-27 2024-05-02 주식회사 케이티앤지 흡입용 저용량 니코틴 건조 분말 조성물
JP2026509962A (ja) * 2022-10-27 2026-03-26 ケーティー アンド ジー コーポレイション 吸入用ニコチン乾燥粉末の製造方法
WO2025213000A1 (en) * 2024-04-05 2025-10-09 ODS Products, LLC Pouches comprising active ingredients

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
US6234169B1 (en) 1998-08-14 2001-05-22 Arthur Slutsky Inhaler
US20040156792A1 (en) * 2002-12-31 2004-08-12 Nektar Therapeutics Pharmaceutical formulation with an insoluble active agent
US6766799B2 (en) 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
ES2310722T3 (es) 2003-03-20 2009-01-16 Galephar M/F Sistema inhalador de polvo seco mejorado.
US8037880B2 (en) 2006-04-07 2011-10-18 The University Of Western Ontario Dry powder inhaler
EP2077882A2 (en) 2006-10-25 2009-07-15 Nektar Therapeutics Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
CN101888867B (zh) 2007-12-05 2013-05-15 诺瓦提斯公司 用于可雾化的药物制剂的容器
US8772886B2 (en) 2010-07-26 2014-07-08 Avalanche Technology, Inc. Spin transfer torque magnetic random access memory (STTMRAM) having graded synthetic free layer
EP2714162B1 (de) * 2011-05-27 2020-01-01 Boehringer Ingelheim International GmbH Inhalator und kapsel für einen inhalator
EP2614848B1 (de) * 2012-01-13 2020-07-01 Boehringer Ingelheim International GmbH Inhalator und Kapsel für einen Inhalator
US10786637B2 (en) * 2011-07-13 2020-09-29 Pharmaxis Ltd. Delivery devices
US20140150787A1 (en) * 2012-12-04 2014-06-05 Civitas Therapeutics, Inc. Devices and methods for puncturing a capsule to release a powdered medicament therefrom
CA2944471C (en) * 2014-04-08 2020-03-31 Philip Morris Products S.A. Nicotine formulations and methods of making the same
CA2943746C (en) * 2014-04-28 2023-08-15 Philip Morris Products S.A. Flavoured nicotine powder inhaler
MX2016016518A (es) 2014-06-20 2017-05-01 Philip Morris Products Sa Sistema de siministro de polvo de nicotina con medios para el manejo del flujo de aire.
GB201411526D0 (en) * 2014-06-27 2014-08-13 British American Tobacco Co Powder
US9585835B1 (en) * 2015-09-16 2017-03-07 Sansa Corporation (Barbados) Inc. Inhalable nicotine formulations and methods of making and using the same
US10149844B2 (en) * 2015-09-16 2018-12-11 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
US11224594B2 (en) * 2015-09-16 2022-01-18 Philip Morris Products S.A. Nicotine formulations and methods of making and using the same
CN117695207A (zh) * 2015-12-24 2024-03-15 菲利普莫里斯生产公司 带香味尼古丁粉末
EP3393560B1 (en) 2015-12-24 2020-03-25 Philip Morris Products S.a.s. Nicotine powder delivery system
CA3008996A1 (en) * 2015-12-24 2017-06-29 Philip Morris Products S.A. Nicotine particle capsule
KR102494208B1 (ko) 2016-11-30 2023-02-02 필립모리스 프로덕츠 에스.에이. 소용돌이 단부 플러그를 갖는 흡입기

Also Published As

Publication number Publication date
JP2023078269A (ja) 2023-06-06
JP2020527377A (ja) 2020-09-10
PH12019502100A1 (en) 2020-03-16
US20200196674A1 (en) 2020-06-25
IL269275B (en) 2022-12-01
ZA201905999B (en) 2021-01-27
CN117958505A (zh) 2024-05-03
MX2019014671A (es) 2020-02-07
AU2018292732B2 (en) 2024-07-04
RU2019141658A3 (https=) 2021-10-14
MY200258A (en) 2023-12-17
BR112019025635A2 (pt) 2020-06-23
RU2019141658A (ru) 2021-07-28
IL269275A (en) 2019-11-28
AU2018292732A1 (en) 2019-10-03
CN110709063A (zh) 2020-01-17
KR20200023285A (ko) 2020-03-04
IL269275B2 (en) 2023-04-01
EP3644962A1 (en) 2020-05-06
WO2019003118A1 (en) 2019-01-03
US12263242B2 (en) 2025-04-01
UA126238C2 (uk) 2022-09-07
KR20240119177A (ko) 2024-08-06

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