CN1106412A - 1-(2-氟环丙基)喹诺酮甲酸和1-(2-氟环丙基)二氮杂萘酮甲酸的衍生物 - Google Patents

1-(2-氟环丙基)喹诺酮甲酸和1-(2-氟环丙基)二氮杂萘酮甲酸的衍生物 Download PDF

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Publication number
CN1106412A
CN1106412A CN94118475A CN94118475A CN1106412A CN 1106412 A CN1106412 A CN 1106412A CN 94118475 A CN94118475 A CN 94118475A CN 94118475 A CN94118475 A CN 94118475A CN 1106412 A CN1106412 A CN 1106412A
Authority
CN
China
Prior art keywords
dihydro
acid
compound
oxygen
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN94118475A
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English (en)
Chinese (zh)
Inventor
U·彼得森
T·申克
S·博姆
R·格罗泽
K·D·布伦姆
R·恩达曼
K·G·梅茨格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of CN1106412A publication Critical patent/CN1106412A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN94118475A 1993-11-16 1994-11-16 1-(2-氟环丙基)喹诺酮甲酸和1-(2-氟环丙基)二氮杂萘酮甲酸的衍生物 Pending CN1106412A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4339134A DE4339134A1 (de) 1993-11-16 1993-11-16 1-(2-Fluorcyclopropyl)-chinolon- und -naphthyridoncarbonsäure-Derivate
DEP4339134.6 1993-11-16

Publications (1)

Publication Number Publication Date
CN1106412A true CN1106412A (zh) 1995-08-09

Family

ID=6502741

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94118475A Pending CN1106412A (zh) 1993-11-16 1994-11-16 1-(2-氟环丙基)喹诺酮甲酸和1-(2-氟环丙基)二氮杂萘酮甲酸的衍生物

Country Status (27)

Country Link
US (1) US5545642A (enExample)
EP (1) EP0653425A1 (enExample)
JP (1) JPH07188230A (enExample)
KR (1) KR950014114A (enExample)
CN (1) CN1106412A (enExample)
AU (2) AU681703B2 (enExample)
BG (1) BG62003B1 (enExample)
CA (1) CA2135548A1 (enExample)
CO (1) CO4180605A1 (enExample)
CZ (1) CZ280594A3 (enExample)
DE (1) DE4339134A1 (enExample)
EE (1) EE9400240A (enExample)
FI (1) FI945360L (enExample)
HR (1) HRP940833A2 (enExample)
HU (1) HUT70175A (enExample)
IL (1) IL111624A0 (enExample)
LV (1) LV11328B (enExample)
NO (1) NO302367B1 (enExample)
NZ (1) NZ264905A (enExample)
PE (1) PE32395A1 (enExample)
PL (1) PL305862A1 (enExample)
RU (1) RU94040885A (enExample)
SK (1) SK137194A3 (enExample)
SV (1) SV1994000064A (enExample)
TW (1) TW273547B (enExample)
YU (1) YU65494A (enExample)
ZA (1) ZA949052B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100236852B1 (ko) * 1992-10-09 2000-03-02 나가야마 오사무 플루오로 퀴놀린 유도체
JP3468244B2 (ja) * 1995-12-22 2003-11-17 ナガセケムテックス株式会社 抗ヘリコバクターピロリ剤
WO1998058928A1 (fr) * 1997-06-23 1998-12-30 Yoshitomi Pharmaceutical Industries, Ltd. Agent prophylactique ou therapeutique contre des maladies attribuables a une infection par des helicobacters
DE10108750A1 (de) 2001-02-23 2002-09-05 Bayer Ag Verbessertes Verfahren zur Herstellung von Fluorchinoloncarbonsäuren
US7915418B2 (en) * 2003-06-06 2011-03-29 Daiichi Pharmaceutical Co., Ltd. Intermediates and process for the production of optically active quinolonecarboxylic acid derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5274167A (en) * 1989-01-26 1993-12-28 Bayer Aktiengesellschaft Polymeriable optically active (meth) acrylic acid derivatives
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
KR910009331B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 디아자비시클로아민 화합물과 그의 제조방법
KR910009330B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
KR910009333B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
DE69231422T2 (de) * 1991-05-28 2001-03-29 Daiichi Pharmaceutical Co., Ltd. Pyridoncarbonsäurederivate
DE4121214A1 (de) * 1991-06-27 1993-01-14 Bayer Ag 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
EP0550016A1 (en) * 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and processes for preparing same
WO1994025464A1 (en) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same

Also Published As

Publication number Publication date
YU65494A (sh) 1997-09-30
AU681703B2 (en) 1997-09-04
BG62003B1 (bg) 1998-12-30
NO944365D0 (no) 1994-11-15
FI945360A7 (fi) 1995-05-17
FI945360L (fi) 1995-05-17
EE9400240A (et) 1996-02-15
NO944365L (no) 1995-05-18
TW273547B (enExample) 1996-04-01
CA2135548A1 (en) 1995-05-17
LV11328A (lv) 1996-06-20
HRP940833A2 (en) 1996-12-31
SK137194A3 (en) 1995-06-07
NZ264905A (en) 1995-11-27
AU7773094A (en) 1995-05-25
NO302367B1 (no) 1998-02-23
PE32395A1 (es) 1995-12-15
DE4339134A1 (de) 1995-05-18
CZ280594A3 (en) 1995-08-16
US5545642A (en) 1996-08-13
AU2559997A (en) 1997-09-04
JPH07188230A (ja) 1995-07-25
CO4180605A1 (es) 1995-06-07
EP0653425A1 (de) 1995-05-17
HUT70175A (en) 1995-09-28
HU9403288D0 (en) 1995-01-30
RU94040885A (ru) 1996-11-20
SV1994000064A (es) 1995-05-25
LV11328B (en) 1996-12-20
PL305862A1 (en) 1995-05-29
ZA949052B (en) 1995-07-19
BG99179A (en) 1995-07-28
IL111624A0 (en) 1995-01-24
KR950014114A (ko) 1995-06-15
FI945360A0 (fi) 1994-11-14

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