CN110628822A - 重配btv和ahsv疫苗 - Google Patents

重配btv和ahsv疫苗 Download PDF

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Publication number
CN110628822A
CN110628822A CN201910804847.8A CN201910804847A CN110628822A CN 110628822 A CN110628822 A CN 110628822A CN 201910804847 A CN201910804847 A CN 201910804847A CN 110628822 A CN110628822 A CN 110628822A
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China
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leu
glu
ile
arg
ala
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CN201910804847.8A
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English (en)
Chinese (zh)
Inventor
M·帕尔马里尼
P·于代莱
J-C·奥多内
S·F·努涅斯
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Glasgow Administration, University of
Merial Ltd
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Glasgow Administration, University of
Merial Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12121Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12171Demonstrated in vivo effect

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201910804847.8A 2012-06-13 2013-06-13 重配btv和ahsv疫苗 Pending CN110628822A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261659198P 2012-06-13 2012-06-13
US61/659,198 2012-06-13
CN201380038286.6A CN104582724A (zh) 2012-06-13 2013-06-13 重配btv和ahsv疫苗

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201380038286.6A Division CN104582724A (zh) 2012-06-13 2013-06-13 重配btv和ahsv疫苗

Publications (1)

Publication Number Publication Date
CN110628822A true CN110628822A (zh) 2019-12-31

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN201910804847.8A Pending CN110628822A (zh) 2012-06-13 2013-06-13 重配btv和ahsv疫苗
CN201380038286.6A Pending CN104582724A (zh) 2012-06-13 2013-06-13 重配btv和ahsv疫苗

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201380038286.6A Pending CN104582724A (zh) 2012-06-13 2013-06-13 重配btv和ahsv疫苗

Country Status (17)

Country Link
US (1) US10801039B2 (https=)
EP (1) EP2861248B1 (https=)
JP (1) JP6347257B2 (https=)
KR (1) KR102136437B1 (https=)
CN (2) CN110628822A (https=)
AU (2) AU2013274191B2 (https=)
BR (1) BR112014031133B1 (https=)
CA (1) CA2876196C (https=)
ES (1) ES2664069T3 (https=)
IL (1) IL236148B (https=)
MA (1) MA37749B1 (https=)
MX (1) MX364875B (https=)
NZ (1) NZ703297A (https=)
RU (1) RU2656187C2 (https=)
TN (1) TN2014000518A1 (https=)
WO (1) WO2013188673A2 (https=)
ZA (1) ZA201409124B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
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CN112375848A (zh) * 2020-12-11 2021-02-19 云南省畜牧兽医科学院 一种蓝舌病病毒血清型鉴定的RT-qPCR检测试剂盒和方法

Families Citing this family (8)

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US11053509B2 (en) 2016-04-19 2021-07-06 Csir Plant-produced chimaeric Orbivirus VLPs
AU2017256071B2 (en) * 2016-04-26 2022-11-17 London School Of Hygiene & Tropical Medicine Reoviridae vaccine
WO2018103038A1 (zh) * 2016-12-08 2018-06-14 拜西欧斯(北京)生物技术有限公司 一种缀合物及其应用
CN109897092B (zh) * 2019-04-02 2019-11-19 深圳海关动植物检验检疫技术中心 一种蓝舌病病毒非结构蛋白ns3的可溶制备方法
CN110016466B (zh) * 2019-05-21 2022-09-13 云南省畜牧兽医科学院 特异性检测蓝舌病病毒的单抗及其杂交瘤细胞株和应用
CN110257560B (zh) * 2019-07-23 2023-06-27 深圳海关动植物检验检疫技术中心 一种用于蓝舌病病毒8型检测的试剂、检测方法及应用
CN116024183B (zh) * 2023-02-15 2023-10-31 中国农业科学院兰州兽医研究所 一种用于荧光染色的重组蓝舌病毒及其构建方法
CN120271699B (zh) * 2025-04-10 2026-03-31 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一株特异识别蓝舌病毒vp5蛋白的单克隆抗体

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112375848A (zh) * 2020-12-11 2021-02-19 云南省畜牧兽医科学院 一种蓝舌病病毒血清型鉴定的RT-qPCR检测试剂盒和方法

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Publication number Publication date
JP2015525076A (ja) 2015-09-03
US20130337010A1 (en) 2013-12-19
BR112014031133A2 (https=) 2017-08-15
WO2013188673A3 (en) 2014-03-27
MX364875B (es) 2019-05-09
ZA201409124B (en) 2017-05-31
KR102136437B1 (ko) 2020-07-21
IL236148A0 (en) 2015-01-29
MA37749B1 (fr) 2017-05-31
WO2013188673A2 (en) 2013-12-19
MA37749A1 (fr) 2016-08-31
MX2014015311A (es) 2016-04-04
US10801039B2 (en) 2020-10-13
HK1209326A1 (en) 2016-04-01
BR112014031133B1 (pt) 2023-02-07
TN2014000518A1 (en) 2016-03-30
IL236148B (en) 2019-05-30
JP6347257B2 (ja) 2018-06-27
RU2656187C2 (ru) 2018-05-31
AU2016235036A1 (en) 2016-10-27
KR20150036057A (ko) 2015-04-07
RU2015100269A (ru) 2016-08-10
AU2013274191A1 (en) 2015-01-22
CA2876196C (en) 2021-09-21
EP2861248B1 (en) 2017-11-15
AU2013274191B2 (en) 2016-09-22
EP2861248A2 (en) 2015-04-22
NZ703297A (en) 2016-04-29
CA2876196A1 (en) 2013-12-19
CN104582724A (zh) 2015-04-29
ES2664069T3 (es) 2018-04-18

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