TN2014000518A1 - Reassortant btv and ahsv vaccines - Google Patents

Reassortant btv and ahsv vaccines

Info

Publication number
TN2014000518A1
TN2014000518A1 TN2014000518A TN2014000518A TN2014000518A1 TN 2014000518 A1 TN2014000518 A1 TN 2014000518A1 TN 2014000518 A TN2014000518 A TN 2014000518A TN 2014000518 A TN2014000518 A TN 2014000518A TN 2014000518 A1 TN2014000518 A1 TN 2014000518A1
Authority
TN
Tunisia
Prior art keywords
vaccines
btv
ahsv
ashv
reassortant
Prior art date
Application number
TN2014000518A
Other languages
English (en)
French (fr)
Inventor
Massimo Palmarini
Pascal Hudelet
Jean-Christophe Audonnet
Sandro Filipe Nunes
Original Assignee
Merial Ltd
Univ Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd, Univ Glasgow filed Critical Merial Ltd
Publication of TN2014000518A1 publication Critical patent/TN2014000518A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12121Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12171Demonstrated in vivo effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
TN2014000518A 2012-06-13 2014-12-12 Reassortant btv and ahsv vaccines TN2014000518A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261659198P 2012-06-13 2012-06-13
PCT/US2013/045667 WO2013188673A2 (en) 2012-06-13 2013-06-13 Reassortant btv and ahsv vaccines

Publications (1)

Publication Number Publication Date
TN2014000518A1 true TN2014000518A1 (en) 2016-03-30

Family

ID=49237584

Family Applications (1)

Application Number Title Priority Date Filing Date
TN2014000518A TN2014000518A1 (en) 2012-06-13 2014-12-12 Reassortant btv and ahsv vaccines

Country Status (17)

Country Link
US (1) US10801039B2 (https=)
EP (1) EP2861248B1 (https=)
JP (1) JP6347257B2 (https=)
KR (1) KR102136437B1 (https=)
CN (2) CN110628822A (https=)
AU (2) AU2013274191B2 (https=)
BR (1) BR112014031133B1 (https=)
CA (1) CA2876196C (https=)
ES (1) ES2664069T3 (https=)
IL (1) IL236148B (https=)
MA (1) MA37749B1 (https=)
MX (1) MX364875B (https=)
NZ (1) NZ703297A (https=)
RU (1) RU2656187C2 (https=)
TN (1) TN2014000518A1 (https=)
WO (1) WO2013188673A2 (https=)
ZA (1) ZA201409124B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11053509B2 (en) 2016-04-19 2021-07-06 Csir Plant-produced chimaeric Orbivirus VLPs
AU2017256071B2 (en) * 2016-04-26 2022-11-17 London School Of Hygiene & Tropical Medicine Reoviridae vaccine
WO2018103038A1 (zh) * 2016-12-08 2018-06-14 拜西欧斯(北京)生物技术有限公司 一种缀合物及其应用
CN109897092B (zh) * 2019-04-02 2019-11-19 深圳海关动植物检验检疫技术中心 一种蓝舌病病毒非结构蛋白ns3的可溶制备方法
CN110016466B (zh) * 2019-05-21 2022-09-13 云南省畜牧兽医科学院 特异性检测蓝舌病病毒的单抗及其杂交瘤细胞株和应用
CN110257560B (zh) * 2019-07-23 2023-06-27 深圳海关动植物检验检疫技术中心 一种用于蓝舌病病毒8型检测的试剂、检测方法及应用
CN112375848A (zh) * 2020-12-11 2021-02-19 云南省畜牧兽医科学院 一种蓝舌病病毒血清型鉴定的RT-qPCR检测试剂盒和方法
CN116024183B (zh) * 2023-02-15 2023-10-31 中国农业科学院兰州兽医研究所 一种用于荧光染色的重组蓝舌病毒及其构建方法
CN120271699B (zh) * 2025-04-10 2026-03-31 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一株特异识别蓝舌病毒vp5蛋白的单克隆抗体

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US5505941A (en) 1981-12-24 1996-04-09 Health Research, Inc. Recombinant avipox virus and method to induce an immune response
CA1247080A (en) 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
EP0173552B1 (en) 1984-08-24 1991-10-09 The Upjohn Company Recombinant dna compounds and the expression of polypeptides such as tpa
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4968615A (en) 1985-12-18 1990-11-06 Ciba-Geigy Corporation Deoxyribonucleic acid segment from a virus
US4963481A (en) 1985-12-18 1990-10-16 Genetics Institute Inc Promoter system
AU613316B2 (en) 1986-09-12 1991-08-01 Genentech Inc. Improved recombinant expression
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
DE3743138A1 (de) 1987-12-18 1989-09-14 Mayr Christian Gmbh & Co Kg Schleifringlose, elektromagnetische ueberlastkupplung
DE69233158T2 (de) 1991-03-07 2004-05-13 Connaught Technology Corp., Greenville Gentechnologisch hergestellter stamm für impfstoffe
JPH11504631A (ja) 1995-04-25 1999-04-27 バイカル インコーポレイテッド Dna/脂質複合体の単一バイアル製剤
US5846946A (en) 1996-06-14 1998-12-08 Pasteur Merieux Serums Et Vaccins Compositions and methods for administering Borrelia DNA
FR2751228B1 (fr) 1996-07-19 1998-11-20 Rhone Merieux Vaccin polynucleotidique bovin pour voie intradermique
FR2751226B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies du cheval
FR2751225B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique aviaire
FR2751224B1 (fr) 1996-07-19 1998-11-20 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
FR2751229B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins
FR2751227B1 (fr) 1996-07-19 1998-11-27 Rhone Merieux Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives
ATE292980T1 (de) 1996-10-11 2005-04-15 Univ California Immunostimulierende oligonucleotidekonjugate
AU8444798A (en) 1997-06-30 1999-01-25 Centre National De La Recherche Scientifique Improved method for transferring nucleic acid into the striped muscle and combination therefor
FR2778858B1 (fr) 1998-05-20 2000-06-16 Oreal Emulsion e/h/e stable et son utilisation comme composition cosmetique et/ou dermatologique
FR2801607B1 (fr) 1999-11-26 2001-12-28 Merial Sas Pneumovirus du canard et vaccins correspondants
US6852705B2 (en) 2000-01-21 2005-02-08 Merial DNA vaccines for farm animals, in particular bovines and porcines
US7371395B2 (en) 2003-07-24 2008-05-13 Merial Limited Vaccine formulations
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
EP2062594A1 (en) * 2007-11-21 2009-05-27 Wyeth Farma, S.A. Bluetongue virus vaccine and immunogenic compositions, methods of use and methods of producing same
JP5619614B2 (ja) * 2007-11-26 2014-11-05 ロンドン スクール オブ ハイジーン アンド トロピカル メディシンLondon School Of Hygiene & Tropical Medicine レオウイルス科のウイルスのワクチン用ウイルス株を製造する方法

Also Published As

Publication number Publication date
JP2015525076A (ja) 2015-09-03
US20130337010A1 (en) 2013-12-19
BR112014031133A2 (https=) 2017-08-15
WO2013188673A3 (en) 2014-03-27
MX364875B (es) 2019-05-09
ZA201409124B (en) 2017-05-31
KR102136437B1 (ko) 2020-07-21
IL236148A0 (en) 2015-01-29
MA37749B1 (fr) 2017-05-31
WO2013188673A2 (en) 2013-12-19
MA37749A1 (fr) 2016-08-31
MX2014015311A (es) 2016-04-04
US10801039B2 (en) 2020-10-13
HK1209326A1 (en) 2016-04-01
BR112014031133B1 (pt) 2023-02-07
IL236148B (en) 2019-05-30
JP6347257B2 (ja) 2018-06-27
CN110628822A (zh) 2019-12-31
RU2656187C2 (ru) 2018-05-31
AU2016235036A1 (en) 2016-10-27
KR20150036057A (ko) 2015-04-07
RU2015100269A (ru) 2016-08-10
AU2013274191A1 (en) 2015-01-22
CA2876196C (en) 2021-09-21
EP2861248B1 (en) 2017-11-15
AU2013274191B2 (en) 2016-09-22
EP2861248A2 (en) 2015-04-22
NZ703297A (en) 2016-04-29
CA2876196A1 (en) 2013-12-19
CN104582724A (zh) 2015-04-29
ES2664069T3 (es) 2018-04-18

Similar Documents

Publication Publication Date Title
TN2014000518A1 (en) Reassortant btv and ahsv vaccines
MX2017001406A (es) Agentes a base de flagelina y usos de los mismos, incluyendo vacunación efectiva.
MY202415A (en) Subcutaneous formulations of anti-cd38 antibodies and their uses
MY181175A (en) Therapeutic hpv16 vaccines
IL257800A (en) Immune compositions with improved stability and immunogenicity
TR201908550T4 (tr) Profilaktik veya terapötik uygulamalar için lipozomal sferik nükleik asitler tarafından immün modülatörlerin çok değerlikli teslimi.
IL248483A0 (en) Different strains of Listeria recombinant vaccines and methods for their production
PT3207053T (pt) Novos péptidos imunogénicos
MX2021001053A (es) Vacunas contra virus de la influenza y sus usos.
MX2018002106A (es) Vacunas terapeuticas contra el hpv18.
SG195114A1 (en) Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use
WO2013106834A3 (en) Immunogenic wt-1 peptides and methods of use thereof
IL251120A0 (en) Immunogenic/therapeutic glycoside preparations and their uses
MY191539A (en) Streptococcal vaccine
ZA201608487B (en) Dual adjuvant vaccine compositions, preparation and uses
IL257194B (en) Targeted delivery of spray-dried formulations to the lungs
IN2013MU00848A (https=)
EP3210621A4 (en) Micellar polypeptide vaccine having pegylated phospholipids as carrier
MX2015015428A (es) Eliminacion de riesgo de narcolepsia en vacunas contra influenza.
SG10201900598TA (en) Factor viii formulation
EP3137111A4 (en) Compositions and methods for intradermal vaccine delivery
ITUB20152497A1 (it) Treno di compressione di gas di carica di etilene
MX2020002793A (es) Composiciones de microesferas de gas encapsulado en lipidos y metodos relacionados.
PL3077512T3 (pl) Immunogenne kompozycje i szczepionki pochodzące od bakteryjnych białek receptora powierzchniowego
NZ721832A (en) Solid forms of tenofovir